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Volumn 30, Issue 10, 2009, Pages 503-508

Precaution, cyclooxygenase inhibition, and cardiovascular risk

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CELECOXIB; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; ETORICOXIB; IBUPROFEN; LUMIRACOXIB; NAPROXEN; PARACETAMOL; PARECOXIB; PLACEBO; ROFECOXIB; THROMBOXANE; VALDECOXIB;

EID: 70349176236     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2009.07.007     Document Type: Article
Times cited : (42)

References (66)
  • 1
    • 12844278633 scopus 로고    scopus 로고
    • Cyclooxygenases, thromboxane, and atherosclerosis: plaque destabilization by cyclooxygenase-2 inhibition combined with thromboxane receptor antagonism
    • Egan K.M., et al. Cyclooxygenases, thromboxane, and atherosclerosis: plaque destabilization by cyclooxygenase-2 inhibition combined with thromboxane receptor antagonism. Circulation 111 (2005) 334-342
    • (2005) Circulation , vol.111 , pp. 334-342
    • Egan, K.M.1
  • 2
    • 9644272529 scopus 로고    scopus 로고
    • Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice
    • Kobayashi T., et al. Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice. J. Clin. Invest. 114 (2004) 784-794
    • (2004) J. Clin. Invest. , vol.114 , pp. 784-794
    • Kobayashi, T.1
  • 3
    • 0021269059 scopus 로고
    • Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation
    • FitzGerald G.A., et al. Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation. N. Engl. J. Med. 310 (1984) 1065-1068
    • (1984) N. Engl. J. Med. , vol.310 , pp. 1065-1068
    • FitzGerald, G.A.1
  • 4
    • 28244459634 scopus 로고    scopus 로고
    • Low-dose aspirin for the prevention of atherothrombosis
    • Patrono C., et al. Low-dose aspirin for the prevention of atherothrombosis. N. Engl. J. Med. 353 (2005) 2373-2383
    • (2005) N. Engl. J. Med. , vol.353 , pp. 2373-2383
    • Patrono, C.1
  • 5
    • 10344267004 scopus 로고    scopus 로고
    • COX-2-derived prostacyclin confers atheroprotection on female mice
    • Egan K.M., et al. COX-2-derived prostacyclin confers atheroprotection on female mice. Science 306 (2004) 1954-1957
    • (2004) Science , vol.306 , pp. 1954-1957
    • Egan, K.M.1
  • 6
    • 0023137593 scopus 로고
    • Inhibition of thromboxane formation in vivo and ex vivo: implications for therapy with platelet-inhibitory drugs
    • Reilly I.A., and FitzGerald G.A. Inhibition of thromboxane formation in vivo and ex vivo: implications for therapy with platelet-inhibitory drugs. Blood 69 (1987) 180-186
    • (1987) Blood , vol.69 , pp. 180-186
    • Reilly, I.A.1    FitzGerald, G.A.2
  • 7
    • 0028120906 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet treatment. I. Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
    • Antiplatelet Trialists' Collaboration
    • Antiplatelet Trialists' Collaboration. Collaborative overview of randomised trials of antiplatelet treatment. I. Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ 308 (1994) 81-106
    • (1994) BMJ , vol.308 , pp. 81-106
  • 8
    • 0033524421 scopus 로고    scopus 로고
    • Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2
    • McAdam B.F., et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 272-277
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 272-277
    • McAdam, B.F.1
  • 9
    • 33847117123 scopus 로고    scopus 로고
    • Balancing prostanoid activity in the human vascular system
    • Flavahan N.A. Balancing prostanoid activity in the human vascular system. Trends Pharmacol. Sci. 28 (2007) 106-110
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 106-110
    • Flavahan, N.A.1
  • 10
    • 0037134011 scopus 로고    scopus 로고
    • 2
    • 2. Science 296 (2002) 539-554
    • (2002) Science , vol.296 , pp. 539-554
    • Cheng, Y.1
  • 11
    • 0034707105 scopus 로고    scopus 로고
    • Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group
    • Bombardier C., et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N. Engl. J. Med. 343 (2000) 1520-1528
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1520-1528
    • Bombardier, C.1
  • 12
    • 14944342151 scopus 로고    scopus 로고
    • COX-2 inhibitors - a lesson in unexpected problems
    • Drazen J.M. COX-2 inhibitors - a lesson in unexpected problems. N. Engl. J. Med. 352 (2005) 1131-1132
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1131-1132
    • Drazen, J.M.1
  • 13
    • 70349183936 scopus 로고    scopus 로고
    • General Product Safety Law
    • Feldschreiber P. (Ed), Oxford University Press
    • Asif J. General Product Safety Law. In: Feldschreiber P. (Ed). The Law and Regulation of Medicines (2008), Oxford University Press 129-164
    • (2008) The Law and Regulation of Medicines , pp. 129-164
    • Asif, J.1
  • 14
    • 33744976771 scopus 로고    scopus 로고
    • Do selective cyclo-oxygenase-2 inhibitors and traditional nonsteroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomized trials
    • Kearney P.M., et al. Do selective cyclo-oxygenase-2 inhibitors and traditional nonsteroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomized trials. BMJ 332 (2006) 1302-1308
    • (2006) BMJ , vol.332 , pp. 1302-1308
    • Kearney, P.M.1
  • 15
    • 33749339372 scopus 로고    scopus 로고
    • Cardiovascular risk and inhibition of cyclo-oxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclo-oxygenase 2
    • McGettigan P., and Henry D. Cardiovascular risk and inhibition of cyclo-oxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclo-oxygenase 2. JAMA 296 (2006) 1633-1644
    • (2006) JAMA , vol.296 , pp. 1633-1644
    • McGettigan, P.1    Henry, D.2
  • 16
    • 29544442045 scopus 로고    scopus 로고
    • Expression of concern
    • Curfman G.D., et al. Expression of concern. N. Engl. J. Med. 353 (2005) 2813-2814
    • (2005) N. Engl. J. Med. , vol.353 , pp. 2813-2814
    • Curfman, G.D.1
  • 17
    • 19744380776 scopus 로고    scopus 로고
    • The Adenomatous Polyp Prevention on Vioxx (APPROVe). Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention Trial
    • Bresalier R.S., et al. The Adenomatous Polyp Prevention on Vioxx (APPROVe). Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention Trial. N. Engl. J. Med. 352 (2005) 1092-1102
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1092-1102
    • Bresalier, R.S.1
  • 18
    • 33745900534 scopus 로고    scopus 로고
    • Adverse effects of rofecoxib
    • Nissen S.E. Adverse effects of rofecoxib. N. Engl. J. Med. 355 (2006) 203-204
    • (2006) N. Engl. J. Med. , vol.355 , pp. 203-204
    • Nissen, S.E.1
  • 19
    • 33745931363 scopus 로고    scopus 로고
    • Adverse effects of rofecoxib
    • Furberg C. Adverse effects of rofecoxib. N. Engl. J. Med. 355 (2006) 204
    • (2006) N. Engl. J. Med. , vol.355 , pp. 204
    • Furberg, C.1
  • 20
    • 13444263619 scopus 로고    scopus 로고
    • Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective anti-inflammatory drugs: nested case control study
    • Graham D.J., et al. Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective anti-inflammatory drugs: nested case control study. Lancet 365 (2005) 475-481
    • (2005) Lancet , vol.365 , pp. 475-481
    • Graham, D.J.1
  • 21
    • 70450241064 scopus 로고    scopus 로고
    • No obvious extra cardiovascular risk associated with low-dose NSAIDs
    • in press
    • Moore, N. (2009) No obvious extra cardiovascular risk associated with low-dose NSAIDs. Clin. Pharm. Therap. (in press)
    • (2009) Clin. Pharm. Therap
    • Moore, N.1
  • 22
    • 55049100980 scopus 로고    scopus 로고
    • Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population
    • Garcia Rodriguez L.A., et al. Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population. J. Am. Coll. Cardiol. 52 (2008) 1628-1636
    • (2008) J. Am. Coll. Cardiol. , vol.52 , pp. 1628-1636
    • Garcia Rodriguez, L.A.1
  • 23
    • 63649148593 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs: past, present and future
    • Patrono C., and Rocca B. Nonsteroidal antiinflammatory drugs: past, present and future. Pharmacological Research 59 (2009) 285-289
    • (2009) Pharmacological Research , vol.59 , pp. 285-289
    • Patrono, C.1    Rocca, B.2
  • 24
    • 70349173439 scopus 로고    scopus 로고
    • The Regulatory Process: pharmacovigilance in practice
    • Feldschreiber P. (Ed), Oxford University Press, Oxford
    • Warren J.B. The Regulatory Process: pharmacovigilance in practice. In: Feldschreiber P. (Ed). The law and Regulation of Medicines (2008), Oxford University Press, Oxford 129-164
    • (2008) The law and Regulation of Medicines , pp. 129-164
    • Warren, J.B.1
  • 25
    • 6044267892 scopus 로고    scopus 로고
    • Failing the public health: rofecoxib, Merck, and the FDA
    • Topol E.J. Failing the public health: rofecoxib, Merck, and the FDA. N. Engl. J. Med. 351 (2004) 1707-1709
    • (2004) N. Engl. J. Med. , vol.351 , pp. 1707-1709
    • Topol, E.J.1
  • 26
    • 33748416499 scopus 로고    scopus 로고
    • Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412
    • Suntharalingam G., et al. Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412. N. Engl. J. Med. 355 (2006) 1018-1028
    • (2006) N. Engl. J. Med. , vol.355 , pp. 1018-1028
    • Suntharalingam, G.1
  • 27
    • 12344259338 scopus 로고    scopus 로고
    • Facile air oxidation of the conjugate base of rofecoxib (Vioxx), a possible contributor to human toxicity
    • Reddy L.R., and Corey E.J. Facile air oxidation of the conjugate base of rofecoxib (Vioxx), a possible contributor to human toxicity. Tetrahedron Lett. 46 (2005) 927-929
    • (2005) Tetrahedron Lett. , vol.46 , pp. 927-929
    • Reddy, L.R.1    Corey, E.J.2
  • 28
    • 55049091594 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and cardiovascular risk: is prostacyclin inhibition the key event?
    • Minuz P. Nonsteroidal anti-inflammatory drugs and cardiovascular risk: is prostacyclin inhibition the key event?. J. Am. Coll. Cardiol. 52 (2008) 1637-1639
    • (2008) J. Am. Coll. Cardiol. , vol.52 , pp. 1637-1639
    • Minuz, P.1
  • 29
    • 0027940487 scopus 로고
    • Biochemical and pharmacological characterization of the cyclo-oxygenase activity of human blood prostaglandin endoperoxide synthases
    • Patrignani P., et al. Biochemical and pharmacological characterization of the cyclo-oxygenase activity of human blood prostaglandin endoperoxide synthases. J. Pharmacol. Exp. Ther. 271 (1994) 1705-1712
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 1705-1712
    • Patrignani, P.1
  • 30
    • 47849098518 scopus 로고    scopus 로고
    • Can drug removals involving cyclooxygenase-2 inhibitors be avoided? A plea for human pharmacology
    • Hinz B., and Burne K. Can drug removals involving cyclooxygenase-2 inhibitors be avoided? A plea for human pharmacology. Trends Pharmacol. Sci. 29 (2008) 391-397
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 391-397
    • Hinz, B.1    Burne, K.2
  • 31
    • 0018830990 scopus 로고
    • Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects
    • Patrono C., et al. Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. Thromb. Res. 17 (1980) 317-327
    • (1980) Thromb. Res. , vol.17 , pp. 317-327
    • Patrono, C.1
  • 32
    • 0030022032 scopus 로고    scopus 로고
    • A human whole blood assay for clinical evaluation of biochemical efficacy of cyclo-oxygenase inhibitors
    • Brideau C., et al. A human whole blood assay for clinical evaluation of biochemical efficacy of cyclo-oxygenase inhibitors. Inflamm. Res. 45 (1996) 68-74
    • (1996) Inflamm. Res. , vol.45 , pp. 68-74
    • Brideau, C.1
  • 33
    • 0020586721 scopus 로고
    • Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease
    • FitzGerald G.A., et al. Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease. Circulation 67 (1983) 1174-1177
    • (1983) Circulation , vol.67 , pp. 1174-1177
    • FitzGerald, G.A.1
  • 34
    • 0019988413 scopus 로고
    • Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects
    • Patrignani P., et al. Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects. Clin. Invest. 69 (1982) 1366-1372
    • (1982) Clin. Invest. , vol.69 , pp. 1366-1372
    • Patrignani, P.1
  • 35
    • 0025925211 scopus 로고
    • Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin
    • Clarke R.J., et al. Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin. N. Engl. J. Med. 325 (1991) 1137-1141
    • (1991) N. Engl. J. Med. , vol.325 , pp. 1137-1141
    • Clarke, R.J.1
  • 36
    • 0023718515 scopus 로고
    • Effects of intermittent treatment with aspirin on thromboxane and prostacyclin formation in patients with acute myocardial infarction
    • Rasmanis G., et al. Effects of intermittent treatment with aspirin on thromboxane and prostacyclin formation in patients with acute myocardial infarction. Lancet 2 (1988) 245-247
    • (1988) Lancet , vol.2 , pp. 245-247
    • Rasmanis, G.1
  • 37
    • 0032948948 scopus 로고    scopus 로고
    • Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids
    • Catella-Lawson F., et al. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. J. Pharmacol. Exp. Ther. 289 (1999) 735-741
    • (1999) J. Pharmacol. Exp. Ther. , vol.289 , pp. 735-741
    • Catella-Lawson, F.1
  • 38
    • 0033673612 scopus 로고    scopus 로고
    • Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers
    • Van Hecken A., et al. Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. J. Clin. Pharmacol. 40 (2000) 1109-1120
    • (2000) J. Clin. Pharmacol. , vol.40 , pp. 1109-1120
    • Van Hecken, A.1
  • 39
    • 0242690224 scopus 로고    scopus 로고
    • Cox-2 and beyond: approaches to prostaglandin inhibition in human disease
    • FitzGerald G.A. Cox-2 and beyond: approaches to prostaglandin inhibition in human disease. Nat. Rev. Drug Discov. 2 (2003) 879-890
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 879-890
    • FitzGerald, G.A.1
  • 40
    • 23844442838 scopus 로고    scopus 로고
    • Contribution of cyclooxygenase-2 to elevated biosynthesis of thromboxane A2 and prostacyclin
    • McAdam B.F., and Byrne D. Contribution of cyclooxygenase-2 to elevated biosynthesis of thromboxane A2 and prostacyclin. Circulation 112 (2005) 1024-1029
    • (2005) Circulation , vol.112 , pp. 1024-1029
    • McAdam, B.F.1    Byrne, D.2
  • 41
    • 44049106055 scopus 로고    scopus 로고
    • Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects
    • Schwartz J.I., et al. Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects. J. Clin. Pharmacol. 48 (2008) 745-754
    • (2008) J. Clin. Pharmacol. , vol.48 , pp. 745-754
    • Schwartz, J.I.1
  • 42
    • 0036966124 scopus 로고    scopus 로고
    • The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity
    • Tacconelli S., et al. The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity. Curr. Med. Res. Opin. 18 (2002) 503-511
    • (2002) Curr. Med. Res. Opin. , vol.18 , pp. 503-511
    • Tacconelli, S.1
  • 43
    • 0037407092 scopus 로고    scopus 로고
    • The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial
    • Leese P.T., et al. The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial. J. Clin. Pharmacol. 43 (2003) 504-513
    • (2003) J. Clin. Pharmacol. , vol.43 , pp. 504-513
    • Leese, P.T.1
  • 44
    • 34250317428 scopus 로고    scopus 로고
    • Effects of parecoxib and dipyrone on platelet aggregation in patients undergoing meniscectomy: A double-blind, randomized, parallel-group study
    • Graff J., et al. Effects of parecoxib and dipyrone on platelet aggregation in patients undergoing meniscectomy: A double-blind, randomized, parallel-group study. Clinical Therapeutics 29 (2007) 438-447
    • (2007) Clinical Therapeutics , vol.29 , pp. 438-447
    • Graff, J.1
  • 45
    • 0037568022 scopus 로고    scopus 로고
    • Characterization of etoricoxib, a novel, selective COX-2 inhibitor
    • Dallob A., et al. Characterization of etoricoxib, a novel, selective COX-2 inhibitor. J. Clin. Pharmacol. 43 (2003) 573-585
    • (2003) J. Clin. Pharmacol. , vol.43 , pp. 573-585
    • Dallob, A.1
  • 46
    • 10744232651 scopus 로고    scopus 로고
    • Pharmacology and gastrointestinal safety of lumiracoxib, a novel cyclooxygenase2 selective inhibitor an integrated study
    • Atherton C.T., et al. Pharmacology and gastrointestinal safety of lumiracoxib, a novel cyclooxygenase2 selective inhibitor an integrated study. Clin. Gastroenterol. Hepatol. 4 (2004) 113-120
    • (2004) Clin. Gastroenterol. Hepatol. , vol.4 , pp. 113-120
    • Atherton, C.T.1
  • 47
    • 70349174859 scopus 로고    scopus 로고
    • Scott, G. et al. (2003) Multiple dose lumiracoxib shows rapid absorption and COX-2 selectivity without accumulation in patients with rheumatoid arthritis. In Tulunay FC, Orme M, eds. European collaboration towards drug development and rational drug therapy. Proceedings of the Sixth Congress of the European Association for Clinical Pharmacology and Therapeutics. Berlin: Springer, 124, p197
    • Scott, G. et al. (2003) Multiple dose lumiracoxib shows rapid absorption and COX-2 selectivity without accumulation in patients with rheumatoid arthritis. In Tulunay FC, Orme M, eds. European collaboration towards drug development and rational drug therapy. Proceedings of the Sixth Congress of the European Association for Clinical Pharmacology and Therapeutics. Berlin: Springer, 124, p197
  • 48
    • 0024846246 scopus 로고
    • Effects of naproxen on the in vivo synthesis of thromboxane and prostacyclin in man
    • Vesterqvist O., and Gréen K. Effects of naproxen on the in vivo synthesis of thromboxane and prostacyclin in man. Eu. J. Clin. Pharmacol. 37 (1989) 563-565
    • (1989) Eu. J. Clin. Pharmacol. , vol.37 , pp. 563-565
    • Vesterqvist, O.1    Gréen, K.2
  • 49
    • 58849095864 scopus 로고    scopus 로고
    • Lumiracoxib inhibits cyclo-oxygenase 2 completely at the 50 mg dose: is liver toxicity avoidable by adequate dosing?
    • Hinz B., et al. Lumiracoxib inhibits cyclo-oxygenase 2 completely at the 50 mg dose: is liver toxicity avoidable by adequate dosing?. Annals of the Rheumatic Diseases 68 (2009) 289-291
    • (2009) Annals of the Rheumatic Diseases , vol.68 , pp. 289-291
    • Hinz, B.1
  • 50
    • 0346784817 scopus 로고    scopus 로고
    • Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans
    • Kirchheiner J., et al. Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans. Br. J. Clin. Pharmacol. 55 (2003) 51-61
    • (2003) Br. J. Clin. Pharmacol. , vol.55 , pp. 51-61
    • Kirchheiner, J.1
  • 51
    • 0001718662 scopus 로고    scopus 로고
    • Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state
    • Tegeder I., et al. Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state. Clin. Pharmacol. Ther. 65 (1999) 533-544
    • (1999) Clin. Pharmacol. Ther. , vol.65 , pp. 533-544
    • Tegeder, I.1
  • 52
    • 14944371100 scopus 로고    scopus 로고
    • Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery
    • Nussmeier N.A., et al. Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery. N. Engl. J. Med. 352 (2005) 1081-1091
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1081-1091
    • Nussmeier, N.A.1
  • 53
    • 44149106595 scopus 로고    scopus 로고
    • Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation
    • Chen Y.F., et al. Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation. Health Technol. Assess. 11 (2008) 1-278
    • (2008) Health Technol. Assess. , vol.11 , pp. 1-278
    • Chen, Y.F.1
  • 54
    • 42449093389 scopus 로고    scopus 로고
    • Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis
    • Solomon S.D., et al. Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis. Circulation 117 (2008) 2104-2113
    • (2008) Circulation , vol.117 , pp. 2104-2113
    • Solomon, S.D.1
  • 55
    • 63749128221 scopus 로고    scopus 로고
    • Low-Dose Aspirin, Coxibs, and other NSAIDS: A Clinical Mosaic Emerges
    • Patrono C., and Baigent C. Low-Dose Aspirin, Coxibs, and other NSAIDS: A Clinical Mosaic Emerges. Mol. Interv. 9 (2009) 31-39
    • (2009) Mol. Interv. , vol.9 , pp. 31-39
    • Patrono, C.1    Baigent, C.2
  • 56
    • 55749112833 scopus 로고    scopus 로고
    • Selective COX-2 inhibitors: where do we go from here?
    • Baigent C., and Patrono C. Selective COX-2 inhibitors: where do we go from here?. Lancet 372 (2008) 1712-1713
    • (2008) Lancet , vol.372 , pp. 1712-1713
    • Baigent, C.1    Patrono, C.2
  • 57
    • 33645748723 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events
    • Chan A.T., et al. Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events. Circulation 113 (2006) 1578-1587
    • (2006) Circulation , vol.113 , pp. 1578-1587
    • Chan, A.T.1
  • 58
    • 58549116775 scopus 로고    scopus 로고
    • Risk of Myocardial Infarction and Death Associated With the Use of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Among Healthy Individuals: A Nationwide Cohort Study
    • Fosbøl E.L., et al. Risk of Myocardial Infarction and Death Associated With the Use of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Among Healthy Individuals: A Nationwide Cohort Study. Clin Pharmaco & Ther 85 (2009) 190-197
    • (2009) Clin Pharmaco & Ther , vol.85 , pp. 190-197
    • Fosbøl, E.L.1
  • 59
    • 58849157666 scopus 로고    scopus 로고
    • Increased mortality and cardiovascular morbidity associated with use of nonsteroidal anti-inflammatory drugs in chronic heart failure
    • Gislason G.H., et al. Increased mortality and cardiovascular morbidity associated with use of nonsteroidal anti-inflammatory drugs in chronic heart failure. Arch. Intern. Med. 169 (2009) 141-149
    • (2009) Arch. Intern. Med. , vol.169 , pp. 141-149
    • Gislason, G.H.1
  • 60
    • 30344456444 scopus 로고    scopus 로고
    • New insights into the mechanism of action of acetaminophen: Its clinical pharmacologic characteristics reflect its inhibition of the two prostaglandin H2 synthases
    • Aronoff D.M., et al. New insights into the mechanism of action of acetaminophen: Its clinical pharmacologic characteristics reflect its inhibition of the two prostaglandin H2 synthases. Clin. Pharmacol. Ther. 79 (2006) 9
    • (2006) Clin. Pharmacol. Ther. , vol.79 , pp. 9
    • Aronoff, D.M.1
  • 61
    • 38949136999 scopus 로고    scopus 로고
    • Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man
    • Hinz B., et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J. 22 (2008) 383-390
    • (2008) FASEB J. , vol.22 , pp. 383-390
    • Hinz, B.1
  • 62
    • 39649118185 scopus 로고    scopus 로고
    • Acetominophen: antipyretic or hypothermic in mice? In either case, PGHS-1b (COX-3) is irrelevant
    • Li S., et al. Acetominophen: antipyretic or hypothermic in mice? In either case, PGHS-1b (COX-3) is irrelevant. Prostaglan Other Lipid Mediat. 85 (2008) 89-99
    • (2008) Prostaglan Other Lipid Mediat. , vol.85 , pp. 89-99
    • Li, S.1
  • 63
    • 0037076347 scopus 로고    scopus 로고
    • Determinants of of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H2) synthases
    • Boutard O., et al. Determinants of of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H2) synthases. Proc. Nat. Acad. Sci. U.S.A 99 (2002) 7130-7135
    • (2002) Proc. Nat. Acad. Sci. U.S.A , vol.99 , pp. 7130-7135
    • Boutard, O.1
  • 64
    • 0024477239 scopus 로고
    • Pronounced reduction of in vivo prostacyclin synthesis in humans by acetaminophen (paracetamol)
    • Green K., et al. Pronounced reduction of in vivo prostacyclin synthesis in humans by acetaminophen (paracetamol). Prostaglandins 37 (1989) 311-315
    • (1989) Prostaglandins , vol.37 , pp. 311-315
    • Green, K.1
  • 65
    • 0026036587 scopus 로고
    • Effects of non-steroidal anti-inflammatory drugs on the in vivo synthesis of thromboxane and prostacyclin in humans
    • Drvota V., et al. Effects of non-steroidal anti-inflammatory drugs on the in vivo synthesis of thromboxane and prostacyclin in humans. Adv. Prostaglandin Thromboxane Leukot. Res. 21A (1991) 153-156
    • (1991) Adv. Prostaglandin Thromboxane Leukot. Res. , vol.21 A , pp. 153-156
    • Drvota, V.1
  • 66
    • 0025961475 scopus 로고
    • An epidemiologic study of abuse of analgesic drugs: effects of phenacetin and salicylate on mortality and cardiovascular morbidity (1968 to 1987)
    • Dubach U.C., et al. An epidemiologic study of abuse of analgesic drugs: effects of phenacetin and salicylate on mortality and cardiovascular morbidity (1968 to 1987). N. Engl. J. Med. 324 (1991) 155-160
    • (1991) N. Engl. J. Med. , vol.324 , pp. 155-160
    • Dubach, U.C.1


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