-
1
-
-
33645296475
-
Analgesic-antipyretic and anti-inflammatory agents and drugs employed in the treatment of gout
-
Brunton L.L. (Ed), McGraw-Hill, New York, NY, USA
-
Burke A., Smyth E., and FitzGerald G.A. Analgesic-antipyretic and anti-inflammatory agents and drugs employed in the treatment of gout. In: Brunton L.L. (Ed). Goodman & Gilman's the pharmacological basis of therapeutics, (2006), McGraw-Hill, New York, NY, USA 673-715
-
(2006)
Goodman & Gilman's the pharmacological basis of therapeutics
, pp. 673-715
-
-
Burke, A.1
Smyth, E.2
FitzGerald, G.A.3
-
3
-
-
33847051340
-
Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population
-
García Rodríguez L.A., and Barreales Tolosa L. Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population. Gastroenterology 132 (2007) 498-506
-
(2007)
Gastroenterology
, vol.132
, pp. 498-506
-
-
García Rodríguez, L.A.1
Barreales Tolosa, L.2
-
4
-
-
0035833502
-
The coxibs, selective inhibitors of cyclooxygenase-2
-
FitzGerald G.A., and Patrono C. The coxibs, selective inhibitors of cyclooxygenase-2. N Engl J Med 345 (2001) 433-442
-
(2001)
N Engl J Med
, vol.345
, pp. 433-442
-
-
FitzGerald, G.A.1
Patrono, C.2
-
5
-
-
0033933177
-
Differential effects of aspirin and non-aspirin nonsteroidal antiinflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women
-
García Rodríguez L.A., Varas C., and Patrono C. Differential effects of aspirin and non-aspirin nonsteroidal antiinflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women. Epidemiology 11 (2000) 382-387
-
(2000)
Epidemiology
, vol.11
, pp. 382-387
-
-
García Rodríguez, L.A.1
Varas, C.2
Patrono, C.3
-
6
-
-
0034707105
-
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
-
Bombardier C., Laine L., Reicin A., Shapiro D., Burgos-Vargas R., Davis B., et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. N Engl J Med 343 (2000) 1520-1528
-
(2000)
N Engl J Med
, vol.343
, pp. 1520-1528
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
Shapiro, D.4
Burgos-Vargas, R.5
Davis, B.6
-
7
-
-
0034644396
-
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis. The CLASS study: a randomized controlled trial
-
Silverstein F.E., Faich G., Goldstein J.L., Simon L.S., Pincus T., Whelton A., et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis. The CLASS study: a randomized controlled trial. JAMA 284 (2000) 1247-1255
-
(2000)
JAMA
, vol.284
, pp. 1247-1255
-
-
Silverstein, F.E.1
Faich, G.2
Goldstein, J.L.3
Simon, L.S.4
Pincus, T.5
Whelton, A.6
-
8
-
-
4344661128
-
Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial
-
Schnitzer T.J., Burmester G.R., Mysler E., Hochberg M.C., Doherty M., Ehrsam E., et al. Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial. Lancet 364 (2004) 665-675
-
(2004)
Lancet
, vol.364
, pp. 665-675
-
-
Schnitzer, T.J.1
Burmester, G.R.2
Mysler, E.3
Hochberg, M.C.4
Doherty, M.5
Ehrsam, E.6
-
9
-
-
0021022903
-
Arachidonate metabolism in vascular disorders
-
Majerus P.W. Arachidonate metabolism in vascular disorders. J Clin Invest 72 (1983) 1521-1525
-
(1983)
J Clin Invest
, vol.72
, pp. 1521-1525
-
-
Majerus, P.W.1
-
10
-
-
0029790770
-
Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress
-
Topper J.N., Cai J., Falb D., and Gimbrone Jr. M.A. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci USA 93 (1996) 10417-10422
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10417-10422
-
-
Topper, J.N.1
Cai, J.2
Falb, D.3
Gimbrone Jr., M.A.4
-
12
-
-
0033524421
-
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2
-
McAdam B.F., Catella-Lawson F., Mardini I.A., Kapoor S., Lawson J.A., and FitzGerald G.A. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proc Natl Acad Sci USA 96 (1999) 272-277
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 272-277
-
-
McAdam, B.F.1
Catella-Lawson, F.2
Mardini, I.A.3
Kapoor, S.4
Lawson, J.A.5
FitzGerald, G.A.6
-
13
-
-
0037138743
-
Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues
-
Thun M.J., Henley S.J., and Patrono C. Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues. J Natl Cancer Inst 94 (2002) 252-266
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 252-266
-
-
Thun, M.J.1
Henley, S.J.2
Patrono, C.3
-
14
-
-
63649121667
-
Cardiovascular effects of low-dose aspirin, traditional nonsteroidal antiinflammatory drugs and coxibs
-
in press
-
Patrono C, Baigent C. Cardiovascular effects of low-dose aspirin, traditional nonsteroidal antiinflammatory drugs and coxibs. Mol Interv; in press.
-
Mol Interv
-
-
Patrono, C.1
Baigent, C.2
-
15
-
-
33744976771
-
Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials
-
Kearney P.M., Baigent C., Godwin J., Halls H., Emberson J.R., and Patrono C. Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. BMJ 332 (2006) 1302-1308
-
(2006)
BMJ
, vol.332
, pp. 1302-1308
-
-
Kearney, P.M.1
Baigent, C.2
Godwin, J.3
Halls, H.4
Emberson, J.R.5
Patrono, C.6
-
16
-
-
12144290072
-
Clinical pharmacology of platelet, monocyte and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects
-
Capone M.L., Tacconelli S., Sciulli M.G., Grana M., Ricciotti E., Minuz P., et al. Clinical pharmacology of platelet, monocyte and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. Circulation 109 (2004) 1468-1477
-
(2004)
Circulation
, vol.109
, pp. 1468-1477
-
-
Capone, M.L.1
Tacconelli, S.2
Sciulli, M.G.3
Grana, M.4
Ricciotti, E.5
Minuz, P.6
-
17
-
-
34547137897
-
Human pharmacology of naproxen sodium
-
Capone M.L., Tacconelli S., Sciulli M.G., Anzellotti P., Di Francesco L., Merciaro G., et al. Human pharmacology of naproxen sodium. J Pharmacol Exp Ther 322 (2007) 453-460
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 453-460
-
-
Capone, M.L.1
Tacconelli, S.2
Sciulli, M.G.3
Anzellotti, P.4
Di Francesco, L.5
Merciaro, G.6
-
18
-
-
33750944984
-
For the MEDAL Steering Committee, cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison
-
Cannon C.P., Curtis S.P., FitzGerald G.A., Krum H., Kaur A., Bolognese J.A., et al. For the MEDAL Steering Committee, cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Lancet 368 (2006) 1771-1781
-
(2006)
Lancet
, vol.368
, pp. 1771-1781
-
-
Cannon, C.P.1
Curtis, S.P.2
FitzGerald, G.A.3
Krum, H.4
Kaur, A.5
Bolognese, J.A.6
-
19
-
-
37349123992
-
Are COX-2 inhibitors preferable to non-selective non-steroidal anti-inflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin?
-
Strand V. Are COX-2 inhibitors preferable to non-selective non-steroidal anti-inflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin?. Lancet 370 (2007) 2138-2151
-
(2007)
Lancet
, vol.370
, pp. 2138-2151
-
-
Strand, V.1
-
20
-
-
34247464709
-
Use of nonsteroidal antiinflammatory drugs: an update for clinicians: a scientific statement from the American Heart Association
-
Antman E.M., Bennett J.S., Daugherty A., Furberg C., Roberts H., and Taubert K.A. Use of nonsteroidal antiinflammatory drugs: an update for clinicians: a scientific statement from the American Heart Association. Circulation 115 (2007) 1634-1642
-
(2007)
Circulation
, vol.115
, pp. 1634-1642
-
-
Antman, E.M.1
Bennett, J.S.2
Daugherty, A.3
Furberg, C.4
Roberts, H.5
Taubert, K.A.6
-
21
-
-
49549125649
-
-
American College of Rheumatology ad hoc group on use of selective and nonselective nonsteroidal antiinflammatory drugs. Recommendations for use of selective and nonselective nonsteroidal anti-inflammatory drugs: an American College of Rheumatology white paper. Arthritis Rheum 2008;59: 1058-73
-
American College of Rheumatology ad hoc group on use of selective and nonselective nonsteroidal antiinflammatory drugs. Recommendations for use of selective and nonselective nonsteroidal anti-inflammatory drugs: an American College of Rheumatology white paper. Arthritis Rheum 2008;59: 1058-73.
-
-
-
-
22
-
-
55349127823
-
First International Working Party on Gastrointestinal and Cardiovascular Effects of Nonsteroidal Anti-inflammatory Drugs and Anti-platelet Agents. Management of patients on nonsteroidal anti-inflammatory drugs: a clinical practice recommendation from the First International Working Party on Gastrointestinal and Cardiovascular Effects of Nonsteroidal Anti-inflammatory Drugs and Anti-platelet Agents
-
Chan F.K., Abraham N.S., Scheiman J.M., and Laine L. First International Working Party on Gastrointestinal and Cardiovascular Effects of Nonsteroidal Anti-inflammatory Drugs and Anti-platelet Agents. Management of patients on nonsteroidal anti-inflammatory drugs: a clinical practice recommendation from the First International Working Party on Gastrointestinal and Cardiovascular Effects of Nonsteroidal Anti-inflammatory Drugs and Anti-platelet Agents. Am J Gastroenterol 103 (2008) 2908-2918
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 2908-2918
-
-
Chan, F.K.1
Abraham, N.S.2
Scheiman, J.M.3
Laine, L.4
-
23
-
-
42449142348
-
Prescribing pattern of drugs in the treatment of osteoarthritis in italian general practice: the effect of rofecoxib withdrawal
-
Alacqua M., Trifirò G., Cavagna L., Caporali R., Montecucco C.M., Moretti S., et al. Prescribing pattern of drugs in the treatment of osteoarthritis in italian general practice: the effect of rofecoxib withdrawal. Arthritis Rheum 59 (2008) 568-574
-
(2008)
Arthritis Rheum
, vol.59
, pp. 568-574
-
-
Alacqua, M.1
Trifirò, G.2
Cavagna, L.3
Caporali, R.4
Montecucco, C.M.5
Moretti, S.6
-
25
-
-
55049100980
-
Role of dose-potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population
-
García Rodríguez L.A., Tacconelli S., and Patrignani P. Role of dose-potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population. J Am Coll Cardiol 52 (2008) 1628-1636
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 1628-1636
-
-
García Rodríguez, L.A.1
Tacconelli, S.2
Patrignani, P.3
-
26
-
-
55749105531
-
Cardiovascular events associated with rofecoxib: final analysis of the APPROVe trial
-
Baron J.A., Sandler R.S., Bresalier R.S., Lanas A., Morton D.G., Riddell R., et al. Cardiovascular events associated with rofecoxib: final analysis of the APPROVe trial. Lancet 372 (2008) 1756-1764
-
(2008)
Lancet
, vol.372
, pp. 1756-1764
-
-
Baron, J.A.1
Sandler, R.S.2
Bresalier, R.S.3
Lanas, A.4
Morton, D.G.5
Riddell, R.6
-
27
-
-
42449093389
-
For the Cross Trial Safety Assessment Group. Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis
-
Solomon S.D., Wittes J., Finn P.V., Fowler R., Viner J., Bertagnolli M.M., et al. For the Cross Trial Safety Assessment Group. Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis. Circulation 117 (2008) 2104-2113
-
(2008)
Circulation
, vol.117
, pp. 2104-2113
-
-
Solomon, S.D.1
Wittes, J.2
Finn, P.V.3
Fowler, R.4
Viner, J.5
Bertagnolli, M.M.6
-
28
-
-
63649099861
-
Cyclooxygenase-inhibiting nitric oxide donators (CINODs) for osteoarthritis
-
in press
-
Wallace JL, Viappiani S, Bolla M. Cyclooxygenase-inhibiting nitric oxide donators (CINODs) for osteoarthritis. TiPS; in press.
-
TiPS
-
-
Wallace, J.L.1
Viappiani, S.2
Bolla, M.3
-
29
-
-
34748817976
-
Membrane prostaglandin E synthase-1: a novel therapeutic target
-
Samuelsson B., Morgenstern R., and Jakobsson P.-J. Membrane prostaglandin E synthase-1: a novel therapeutic target. Pharmacol Rev 59 (2007) 207-224
-
(2007)
Pharmacol Rev
, vol.59
, pp. 207-224
-
-
Samuelsson, B.1
Morgenstern, R.2
Jakobsson, P.-J.3
-
30
-
-
53849098967
-
MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation
-
Xu D., Rowland S.E., Clark P., Giroux A., Côté B., Guiral S., et al. MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation. J Pharmacol Exp Ther 326 (2008) 754-763
-
(2008)
J Pharmacol Exp Ther
, vol.326
, pp. 754-763
-
-
Xu, D.1
Rowland, S.E.2
Clark, P.3
Giroux, A.4
Côté, B.5
Guiral, S.6
-
31
-
-
33749263692
-
Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis
-
Wang M., Zukas A.M., Hui Y., Ricciotti E., Puré E., and FitzGerald G.A. Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis. Proc Natl Acad Sci USA 103 (2006) 14507-14512
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14507-14512
-
-
Wang, M.1
Zukas, A.M.2
Hui, Y.3
Ricciotti, E.4
Puré, E.5
FitzGerald, G.A.6
-
32
-
-
41649119130
-
Microsomal prostaglandin E2 synthase-1 deletion leads to adverse left ventricular remodeling after myocardial infarction
-
Degousee N., Fazel S., Angoulvant D., Stefanski E., Pawelzik S.C., Korotkova M., et al. Microsomal prostaglandin E2 synthase-1 deletion leads to adverse left ventricular remodeling after myocardial infarction. Circulation 117 (2008) 1701-1710
-
(2008)
Circulation
, vol.117
, pp. 1701-1710
-
-
Degousee, N.1
Fazel, S.2
Angoulvant, D.3
Stefanski, E.4
Pawelzik, S.C.5
Korotkova, M.6
-
33
-
-
34547097777
-
CJ-023,423, a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties
-
Nakao K., Murase A., Ohshiro H., Okumura T., Taniguchi K., Murata Y., et al. CJ-023,423, a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. J Pharmacol Exp Ther 322 (2007) 686-694
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 686-694
-
-
Nakao, K.1
Murase, A.2
Ohshiro, H.3
Okumura, T.4
Taniguchi, K.5
Murata, Y.6
-
34
-
-
42449158937
-
MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3 -methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis
-
Clark P., Rowland S.E., Denis D., Mathieu M.C., Stocco R., Poirier H., et al. MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3 -methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. J Pharmacol Exp Ther 325 (2008) 425-434
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 425-434
-
-
Clark, P.1
Rowland, S.E.2
Denis, D.3
Mathieu, M.C.4
Stocco, R.5
Poirier, H.6
-
35
-
-
37749027812
-
Effect of prostanoid EP4 receptor antagonist, CJ-042,794, in rat models of pain and inflammation
-
Murase A., Okumura T., Sakakibara A., Tonai-Kachi H., Nakao K., and Takada J. Effect of prostanoid EP4 receptor antagonist, CJ-042,794, in rat models of pain and inflammation. Eur J Pharmacol 580 (2008) 116-121
-
(2008)
Eur J Pharmacol
, vol.580
, pp. 116-121
-
-
Murase, A.1
Okumura, T.2
Sakakibara, A.3
Tonai-Kachi, H.4
Nakao, K.5
Takada, J.6
|