Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects

Journal of Clinical Pharmacology

Volumn 48, Issue 6, 2008, Pages 745-754

  Schwartz, Jules I ^a   Dallob, Aimee L ^a   Larson, Patrick J ^a   Laterza, Omar F ^a   Miller, Jutta ^a   Royalty, Jane ^b   Snyder, Karen M ^a   Chappell, Derek L ^a   Hilliard, Deborah A ^a   Flynn, Mary E ^a   Cavanaugh Jr , Paul F ^a   Wagner, John A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Covance GFI Research ^*  (United States)

Author keywords

Celecoxib; Cyclooxygenase inhibitor; Diclofenac; Etoricoxib

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DICLOFENAC; ETORICOXIB; PLACEBO; PROSTAGLANDIN E2; THROMBOXANE B2;

ADULT; ARTICLE; BLOOD CLOTTING; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PROSTAGLANDIN SYNTHESIS; SIDE EFFECT; WEIGHT GAIN;

ADULT; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CROSS-OVER STUDIES; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DICLOFENAC; DINOPROSTONE; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; PYRAZOLES; PYRIDINES; SULFONAMIDES; SULFONES; THROMBOXANE B2;

EID: 44049106055     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270008317590     Document Type: Article

References (50)