메뉴 건너뛰기




Volumn 35, Issue 3, 2009, Pages 609-615

p53 is an important factor for the radiosensitization effect of 2-deoxy-D-glucose

Author keywords

2 deoxy D glucose; Clonogenic survival; Lung cancer; p53; Radiation

Indexed keywords

DEOXYGLUCOSE; PROTEIN P53; SMALL INTERFERING RNA;

EID: 70349153884     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000372     Document Type: Article
Times cited : (14)

References (41)
  • 1
    • 0032843811 scopus 로고    scopus 로고
    • Estimates of the worldwide mortality from 25 cancers in 1990
    • Pisani P, Parkin DM, Bray F and Ferlay J: Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 83: 18-29, 1999.
    • (1999) Int J Cancer , vol.83 , pp. 18-29
    • Pisani, P.1    Parkin, D.M.2    Bray, F.3    Ferlay, J.4
  • 2
    • 70349087668 scopus 로고    scopus 로고
    • Cancer Facts & Figures 2008. American Cancer Society, 2008.
    • Cancer Facts & Figures 2008. American Cancer Society, 2008.
  • 3
    • 0029950535 scopus 로고    scopus 로고
    • United States lung carcinoma incidence trends: Declining for most histologic types among males, increasing among females
    • Travis WD, Lubin J, Ries L and Devesa S: United States lung carcinoma incidence trends: declining for most histologic types among males, increasing among females. Cancer 77: 2464-2470, 1996.
    • (1996) Cancer , vol.77 , pp. 2464-2470
    • Travis, W.D.1    Lubin, J.2    Ries, L.3    Devesa, S.4
  • 4
    • 0345872083 scopus 로고    scopus 로고
    • Multidisciplinary management of lung cancer
    • Spira A and Ettinger DS: Multidisciplinary management of lung cancer. N Engl J Med 350: 379-392, 2004.
    • (2004) N Engl J Med , vol.350 , pp. 379-392
    • Spira, A.1    Ettinger, D.S.2
  • 5
    • 0030772117 scopus 로고    scopus 로고
    • Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival
    • Younes M, Brown RW, Stephenson M, Gondo M and Cagle PT: Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival. Cancer 80: 1046-1051, 1997.
    • (1997) Cancer , vol.80 , pp. 1046-1051
    • Younes, M.1    Brown, R.W.2    Stephenson, M.3    Gondo, M.4    Cagle, P.T.5
  • 6
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O: On the origin of cancer cells. Science 123: 309-314, 1956.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 7
    • 0017580461 scopus 로고
    • Enzymology of cancer cells (second of two parts)
    • Weber G: Enzymology of cancer cells (second of two parts). N Engl J Med 296: 541-551, 1977.
    • (1977) N Engl J Med , vol.296 , pp. 541-551
    • Weber, G.1
  • 9
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: Cancer's Achilles' heel
    • Kroemer G and Pouyssegur J: Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 13: 472-482, 2008.
    • (2008) Cancer Cell , vol.13 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 10
    • 3242753586 scopus 로고    scopus 로고
    • The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis
    • Cuezva JM, Chen G, Alonso AM, et al: The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis. Carcinogenesis 25: 1157-1163, 2004.
    • (2004) Carcinogenesis , vol.25 , pp. 1157-1163
    • Cuezva, J.M.1    Chen, G.2    Alonso, A.M.3
  • 11
    • 35148889082 scopus 로고    scopus 로고
    • Loss of the mitochondrial bioenergetic capacity underlies the glucose avidity of carcinomas
    • Lopez-Rios F, Sanchez-Arago M, Garcia-Garcia E, et al: Loss of the mitochondrial bioenergetic capacity underlies the glucose avidity of carcinomas. Cancer Res 67: 9013-9017, 2007.
    • (2007) Cancer Res , vol.67 , pp. 9013-9017
    • Lopez-Rios, F.1    Sanchez-Arago, M.2    Garcia-Garcia, E.3
  • 12
    • 33750713059 scopus 로고    scopus 로고
    • Effect of 2-deoxy-D-glucose on various malignant cell lines in vitro
    • Zhang XD, Deslandes E, Villedieu M, et al: Effect of 2-deoxy-D-glucose on various malignant cell lines in vitro. Anticancer Res 26: 3561-3566, 2006.
    • (2006) Anticancer Res , vol.26 , pp. 3561-3566
    • Zhang, X.D.1    Deslandes, E.2    Villedieu, M.3
  • 13
    • 0037163688 scopus 로고    scopus 로고
    • Evaluation of 2-deoxy-Dglucose as a chemotherapeutic agent: Mechanism of cell death
    • Aft RL, Zhang FW and Gius D: Evaluation of 2-deoxy-Dglucose as a chemotherapeutic agent: mechanism of cell death. Br J Cancer 87: 805-812, 2002.
    • (2002) Br J Cancer , vol.87 , pp. 805-812
    • Aft, R.L.1    Zhang, F.W.2    Gius, D.3
  • 14
    • 0018601843 scopus 로고
    • Optimization of cancer therapy: Part III - effects of combining 2-deoxy-D-glucose treatment with gamma-irradiation on normal mice
    • Jain VK, Kalia VK, Gopinath PM, Naqvi S and Kucheria K: Optimization of cancer therapy: Part III - effects of combining 2-deoxy-D-glucose treatment with gamma-irradiation on normal mice. Indian J Exp Biol 17: 1320-1325, 1979.
    • (1979) Indian J Exp Biol , vol.17 , pp. 1320-1325
    • Jain, V.K.1    Kalia, V.K.2    Gopinath, P.M.3    Naqvi, S.4    Kucheria, K.5
  • 15
    • 0020314762 scopus 로고
    • Optimization of cancer therapy: Part IV - effects of 2-deoxy-D-glucose on radiation induced chromosomal damage in PHA-stimulated peripheral human leukocytes
    • Kalia VK, Jain VK and Otto FJ: Optimization of cancer therapy: Part IV - effects of 2-deoxy-D-glucose on radiation induced chromosomal damage in PHA-stimulated peripheral human leukocytes. Indian J Exp Biol 20: 884-888, 1982.
    • (1982) Indian J Exp Biol , vol.20 , pp. 884-888
    • Kalia, V.K.1    Jain, V.K.2    Otto, F.J.3
  • 16
    • 0025065024 scopus 로고
    • Effects of 5-bromo-2-deoxyuridine and 2-deoxy-D-glucose on radiation-induced micronuclei in mouse bone marrow
    • Singh SP, Singh S and Jain V: Effects of 5-bromo-2-deoxyuridine and 2-deoxy-D-glucose on radiation-induced micronuclei in mouse bone marrow. Int J Radiat Biol 58: 791-797, 1990.
    • (1990) Int J Radiat Biol , vol.58 , pp. 791-797
    • Singh, S.P.1    Singh, S.2    Jain, V.3
  • 17
    • 23044487054 scopus 로고    scopus 로고
    • Glycolytic inhibitor, 2-deoxy-D-glucose, does not enhance radiation-induced apoptosis in mouse thymocytes and splenocytes in vitro
    • Swamy RK, Manickam J, Adhikari JS and Dwarakanath BS: Glycolytic inhibitor, 2-deoxy-D-glucose, does not enhance radiation-induced apoptosis in mouse thymocytes and splenocytes in vitro. Indian J Exp Biol 43: 686-692, 2005.
    • (2005) Indian J Exp Biol , vol.43 , pp. 686-692
    • Swamy, R.K.1    Manickam, J.2    Adhikari, J.S.3    Dwarakanath, B.S.4
  • 18
    • 0035826677 scopus 로고    scopus 로고
    • Hypersensitization of tumor cells to glycolytic inhibitors
    • Liu H, Hu YP, Savaraj N, Priebe W and Lampidis TJ: Hypersensitization of tumor cells to glycolytic inhibitors. Biochemistry 40: 5542-5547, 2001.
    • (2001) Biochemistry , vol.40 , pp. 5542-5547
    • Liu, H.1    Hu, Y.P.2    Savaraj, N.3    Priebe, W.4    Lampidis, T.J.5
  • 19
    • 0037114462 scopus 로고    scopus 로고
    • Hypoxia increases tumor cell sensitivity to glycolytic inhibitors: A strategy for solid tumor therapy (Model C)
    • Liu H, Savaraj N, Priebe W and Lampidis TJ: Hypoxia increases tumor cell sensitivity to glycolytic inhibitors: a strategy for solid tumor therapy (Model C). Biochem Pharmacol 64: 1745-1751, 2002.
    • (2002) Biochem Pharmacol , vol.64 , pp. 1745-1751
    • Liu, H.1    Savaraj, N.2    Priebe, W.3    Lampidis, T.J.4
  • 20
    • 0442313668 scopus 로고    scopus 로고
    • Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions
    • Maher JC, Krishan A and Lampidis TJ: Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions. Cancer Chemother Pharmacol 53: 116-122, 2004.
    • (2004) Cancer Chemother Pharmacol , vol.53 , pp. 116-122
    • Maher, J.C.1    Krishan, A.2    Lampidis, T.J.3
  • 21
    • 0030152958 scopus 로고    scopus 로고
    • The interaction among glucose transport, hexokinase, and glucose-6-phosphatase with respect to 3H-2-deoxyglucose retention in murine tumor models
    • Nelson CA, Wang JQ, Leav I and Crane PD: The interaction among glucose transport, hexokinase, and glucose-6-phosphatase with respect to 3H-2-deoxyglucose retention in murine tumor models. Nucl Med Biol 23: 533-541, 1996.
    • (1996) Nucl Med Biol , vol.23 , pp. 533-541
    • Nelson, C.A.1    Wang, J.Q.2    Leav, I.3    Crane, P.D.4
  • 22
    • 33751173430 scopus 로고    scopus 로고
    • Altered gene expression induced by ionizing radiation and glycolytic inhibitor 2-deoxy-glucose in a human glioma cell line: Implications for radio sensitization
    • Heminger K, Jain V, Kadakia M, Dwarakanath B and Berberich SJ: Altered gene expression induced by ionizing radiation and glycolytic inhibitor 2-deoxy-glucose in a human glioma cell line: implications for radio sensitization. Cancer Biol Ther 5: 815-823, 2006.
    • (2006) Cancer Biol Ther , vol.5 , pp. 815-823
    • Heminger, K.1    Jain, V.2    Kadakia, M.3    Dwarakanath, B.4    Berberich, S.J.5
  • 23
    • 0030603101 scopus 로고    scopus 로고
    • 2+ and reactive oxygen intermediates as messengers
    • 2+ and reactive oxygen intermediates as messengers. FEBS Lett 392: 129-136, 1996.
    • (1996) FEBS Lett , vol.392 , pp. 129-136
    • Pahl, H.L.1    Baeuerle, P.A.2
  • 24
    • 0038407274 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism
    • Lin X, Zhang F, Bradbury CM, et al: 2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism. Cancer Res 63: 3413-3417, 2003.
    • (2003) Cancer Res , vol.63 , pp. 3413-3417
    • Lin, X.1    Zhang, F.2    Bradbury, C.M.3
  • 25
    • 38149063508 scopus 로고    scopus 로고
    • 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer
    • Coleman MC, Asbury CR, Daniels D, et al: 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer. Free Radic Biol Med 44: 322-331, 2008.
    • (2008) Free Radic Biol Med , vol.44 , pp. 322-331
    • Coleman, M.C.1    Asbury, C.R.2    Daniels, D.3
  • 26
    • 34248142302 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells
    • Simons AL, Ahmad IM, Mattson DM, Dornfeld KJ and Spitz DR: 2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells. Cancer Res 67: 3364-3370, 2007.
    • (2007) Cancer Res , vol.67 , pp. 3364-3370
    • Simons, A.L.1    Ahmad, I.M.2    Mattson, D.M.3    Dornfeld, K.J.4    Spitz, D.R.5
  • 27
    • 1642494855 scopus 로고    scopus 로고
    • 2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo
    • Maschek G, Savaraj N, Priebe W, et al: 2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo. Cancer Res 64: 31-34, 2004.
    • (2004) Cancer Res , vol.64 , pp. 31-34
    • Maschek, G.1    Savaraj, N.2    Priebe, W.3
  • 28
    • 0035879414 scopus 로고    scopus 로고
    • Heterogeneity in 2-deoxy-D-glucose-induced modifications in energetics and radiation responses of human tumor cell lines
    • Dwarkanath BS, Zolzer F, Chandana S, et al: Heterogeneity in 2-deoxy-D-glucose-induced modifications in energetics and radiation responses of human tumor cell lines. Int J Radiat Oncol Biol Phys 50: 1051-1061, 2001.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , pp. 1051-1061
    • Dwarkanath, B.S.1    Zolzer, F.2    Chandana, S.3
  • 29
    • 0027476668 scopus 로고
    • Reversibility of inhibition of DNA double strand break repair by 2-deoxy-D-glucose in Ehrlich ascites tumour cells
    • Jha B and Pohlit W: Reversibility of inhibition of DNA double strand break repair by 2-deoxy-D-glucose in Ehrlich ascites tumour cells. Int J Radiat Biol 63: 459-467, 1993.
    • (1993) Int J Radiat Biol , vol.63 , pp. 459-467
    • Jha, B.1    Pohlit, W.2
  • 30
    • 0030009250 scopus 로고    scopus 로고
    • Improving cancer radiotherapy with 2-deoxy-D-glucose: Phase I/II clinical trials on human cerebral gliomas
    • Mohanti BK, Rath GK, Anantha N, et al: Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trials on human cerebral gliomas. Int J Radiat Oncol Biol Phys 35: 103-111, 1996.
    • (1996) Int J Radiat Oncol Biol Phys , vol.35 , pp. 103-111
    • Mohanti, B.K.1    Rath, G.K.2    Anantha, N.3
  • 31
    • 34249681337 scopus 로고    scopus 로고
    • Bensaad K and Vousden KH: p53: new roles in metabolism. Trends Cell Biol 17: 286-291, 2007.
    • Bensaad K and Vousden KH: p53: new roles in metabolism. Trends Cell Biol 17: 286-291, 2007.
  • 32
    • 20844449238 scopus 로고    scopus 로고
    • AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
    • Jones RG, Plas DR, Kubek S, et al: AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 18: 283-293, 2005.
    • (2005) Mol Cell , vol.18 , pp. 283-293
    • Jones, R.G.1    Plas, D.R.2    Kubek, S.3
  • 33
    • 33745149291 scopus 로고    scopus 로고
    • p53 regulates mitochondrial respiration
    • Matoba S, Kang JG, Patino WD, et al: p53 regulates mitochondrial respiration. Science 312: 1650-1653, 2006.
    • (2006) Science , vol.312 , pp. 1650-1653
    • Matoba, S.1    Kang, J.G.2    Patino, W.D.3
  • 34
    • 11244347171 scopus 로고    scopus 로고
    • Glycolytic enzymes can modulate cellular life span
    • Kondoh H, Lleonart ME, Gil J, et al: Glycolytic enzymes can modulate cellular life span. Cancer Res 65: 177-185, 2005.
    • (2005) Cancer Res , vol.65 , pp. 177-185
    • Kondoh, H.1    Lleonart, M.E.2    Gil, J.3
  • 35
    • 33745918951 scopus 로고    scopus 로고
    • TIGAR, a p53-inducible regulator of glycolysis and apoptosis
    • Bensaad K, Tsuruta A, Selak MA, et al: TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126: 107-120, 2006.
    • (2006) Cell , vol.126 , pp. 107-120
    • Bensaad, K.1    Tsuruta, A.2    Selak, M.A.3
  • 36
    • 39149111234 scopus 로고    scopus 로고
    • 2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress
    • Ahmad IM, Abdalla MY, Aykin-Burns N, et al: 2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress. Free Radic Biol Med 44: 826-834, 2008.
    • (2008) Free Radic Biol Med , vol.44 , pp. 826-834
    • Ahmad, I.M.1    Abdalla, M.Y.2    Aykin-Burns, N.3
  • 37
    • 43049139541 scopus 로고    scopus 로고
    • p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation
    • Kawauchi K, Araki K, Tobiume K and Tanaka N: p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation. Nat Cell Biol 10: 611-618, 2008.
    • (2008) Nat Cell Biol , vol.10 , pp. 611-618
    • Kawauchi, K.1    Araki, K.2    Tobiume, K.3    Tanaka, N.4
  • 40
    • 35449002129 scopus 로고    scopus 로고
    • Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging
    • Simons AL, Fath MA, Mattson DM, et al: Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging. Int J Radiat Oncol Biol Phys 69: 1222-1230, 2007.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 1222-1230
    • Simons, A.L.1    Fath, M.A.2    Mattson, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.