-
1
-
-
0032843811
-
Estimates of the worldwide mortality from 25 cancers in 1990
-
Pisani P, Parkin DM, Bray F and Ferlay J: Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 83: 18-29, 1999.
-
(1999)
Int J Cancer
, vol.83
, pp. 18-29
-
-
Pisani, P.1
Parkin, D.M.2
Bray, F.3
Ferlay, J.4
-
2
-
-
70349087668
-
-
Cancer Facts & Figures 2008. American Cancer Society, 2008.
-
Cancer Facts & Figures 2008. American Cancer Society, 2008.
-
-
-
-
3
-
-
0029950535
-
United States lung carcinoma incidence trends: Declining for most histologic types among males, increasing among females
-
Travis WD, Lubin J, Ries L and Devesa S: United States lung carcinoma incidence trends: declining for most histologic types among males, increasing among females. Cancer 77: 2464-2470, 1996.
-
(1996)
Cancer
, vol.77
, pp. 2464-2470
-
-
Travis, W.D.1
Lubin, J.2
Ries, L.3
Devesa, S.4
-
4
-
-
0345872083
-
Multidisciplinary management of lung cancer
-
Spira A and Ettinger DS: Multidisciplinary management of lung cancer. N Engl J Med 350: 379-392, 2004.
-
(2004)
N Engl J Med
, vol.350
, pp. 379-392
-
-
Spira, A.1
Ettinger, D.S.2
-
5
-
-
0030772117
-
Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival
-
Younes M, Brown RW, Stephenson M, Gondo M and Cagle PT: Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival. Cancer 80: 1046-1051, 1997.
-
(1997)
Cancer
, vol.80
, pp. 1046-1051
-
-
Younes, M.1
Brown, R.W.2
Stephenson, M.3
Gondo, M.4
Cagle, P.T.5
-
6
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O: On the origin of cancer cells. Science 123: 309-314, 1956.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
7
-
-
0017580461
-
Enzymology of cancer cells (second of two parts)
-
Weber G: Enzymology of cancer cells (second of two parts). N Engl J Med 296: 541-551, 1977.
-
(1977)
N Engl J Med
, vol.296
, pp. 541-551
-
-
Weber, G.1
-
9
-
-
44449147036
-
Tumor cell metabolism: Cancer's Achilles' heel
-
Kroemer G and Pouyssegur J: Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 13: 472-482, 2008.
-
(2008)
Cancer Cell
, vol.13
, pp. 472-482
-
-
Kroemer, G.1
Pouyssegur, J.2
-
10
-
-
3242753586
-
The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis
-
Cuezva JM, Chen G, Alonso AM, et al: The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis. Carcinogenesis 25: 1157-1163, 2004.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1157-1163
-
-
Cuezva, J.M.1
Chen, G.2
Alonso, A.M.3
-
11
-
-
35148889082
-
Loss of the mitochondrial bioenergetic capacity underlies the glucose avidity of carcinomas
-
Lopez-Rios F, Sanchez-Arago M, Garcia-Garcia E, et al: Loss of the mitochondrial bioenergetic capacity underlies the glucose avidity of carcinomas. Cancer Res 67: 9013-9017, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 9013-9017
-
-
Lopez-Rios, F.1
Sanchez-Arago, M.2
Garcia-Garcia, E.3
-
12
-
-
33750713059
-
Effect of 2-deoxy-D-glucose on various malignant cell lines in vitro
-
Zhang XD, Deslandes E, Villedieu M, et al: Effect of 2-deoxy-D-glucose on various malignant cell lines in vitro. Anticancer Res 26: 3561-3566, 2006.
-
(2006)
Anticancer Res
, vol.26
, pp. 3561-3566
-
-
Zhang, X.D.1
Deslandes, E.2
Villedieu, M.3
-
13
-
-
0037163688
-
Evaluation of 2-deoxy-Dglucose as a chemotherapeutic agent: Mechanism of cell death
-
Aft RL, Zhang FW and Gius D: Evaluation of 2-deoxy-Dglucose as a chemotherapeutic agent: mechanism of cell death. Br J Cancer 87: 805-812, 2002.
-
(2002)
Br J Cancer
, vol.87
, pp. 805-812
-
-
Aft, R.L.1
Zhang, F.W.2
Gius, D.3
-
14
-
-
0018601843
-
Optimization of cancer therapy: Part III - effects of combining 2-deoxy-D-glucose treatment with gamma-irradiation on normal mice
-
Jain VK, Kalia VK, Gopinath PM, Naqvi S and Kucheria K: Optimization of cancer therapy: Part III - effects of combining 2-deoxy-D-glucose treatment with gamma-irradiation on normal mice. Indian J Exp Biol 17: 1320-1325, 1979.
-
(1979)
Indian J Exp Biol
, vol.17
, pp. 1320-1325
-
-
Jain, V.K.1
Kalia, V.K.2
Gopinath, P.M.3
Naqvi, S.4
Kucheria, K.5
-
15
-
-
0020314762
-
Optimization of cancer therapy: Part IV - effects of 2-deoxy-D-glucose on radiation induced chromosomal damage in PHA-stimulated peripheral human leukocytes
-
Kalia VK, Jain VK and Otto FJ: Optimization of cancer therapy: Part IV - effects of 2-deoxy-D-glucose on radiation induced chromosomal damage in PHA-stimulated peripheral human leukocytes. Indian J Exp Biol 20: 884-888, 1982.
-
(1982)
Indian J Exp Biol
, vol.20
, pp. 884-888
-
-
Kalia, V.K.1
Jain, V.K.2
Otto, F.J.3
-
16
-
-
0025065024
-
Effects of 5-bromo-2-deoxyuridine and 2-deoxy-D-glucose on radiation-induced micronuclei in mouse bone marrow
-
Singh SP, Singh S and Jain V: Effects of 5-bromo-2-deoxyuridine and 2-deoxy-D-glucose on radiation-induced micronuclei in mouse bone marrow. Int J Radiat Biol 58: 791-797, 1990.
-
(1990)
Int J Radiat Biol
, vol.58
, pp. 791-797
-
-
Singh, S.P.1
Singh, S.2
Jain, V.3
-
17
-
-
23044487054
-
Glycolytic inhibitor, 2-deoxy-D-glucose, does not enhance radiation-induced apoptosis in mouse thymocytes and splenocytes in vitro
-
Swamy RK, Manickam J, Adhikari JS and Dwarakanath BS: Glycolytic inhibitor, 2-deoxy-D-glucose, does not enhance radiation-induced apoptosis in mouse thymocytes and splenocytes in vitro. Indian J Exp Biol 43: 686-692, 2005.
-
(2005)
Indian J Exp Biol
, vol.43
, pp. 686-692
-
-
Swamy, R.K.1
Manickam, J.2
Adhikari, J.S.3
Dwarakanath, B.S.4
-
18
-
-
0035826677
-
Hypersensitization of tumor cells to glycolytic inhibitors
-
Liu H, Hu YP, Savaraj N, Priebe W and Lampidis TJ: Hypersensitization of tumor cells to glycolytic inhibitors. Biochemistry 40: 5542-5547, 2001.
-
(2001)
Biochemistry
, vol.40
, pp. 5542-5547
-
-
Liu, H.1
Hu, Y.P.2
Savaraj, N.3
Priebe, W.4
Lampidis, T.J.5
-
19
-
-
0037114462
-
Hypoxia increases tumor cell sensitivity to glycolytic inhibitors: A strategy for solid tumor therapy (Model C)
-
Liu H, Savaraj N, Priebe W and Lampidis TJ: Hypoxia increases tumor cell sensitivity to glycolytic inhibitors: a strategy for solid tumor therapy (Model C). Biochem Pharmacol 64: 1745-1751, 2002.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 1745-1751
-
-
Liu, H.1
Savaraj, N.2
Priebe, W.3
Lampidis, T.J.4
-
20
-
-
0442313668
-
Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions
-
Maher JC, Krishan A and Lampidis TJ: Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions. Cancer Chemother Pharmacol 53: 116-122, 2004.
-
(2004)
Cancer Chemother Pharmacol
, vol.53
, pp. 116-122
-
-
Maher, J.C.1
Krishan, A.2
Lampidis, T.J.3
-
21
-
-
0030152958
-
The interaction among glucose transport, hexokinase, and glucose-6-phosphatase with respect to 3H-2-deoxyglucose retention in murine tumor models
-
Nelson CA, Wang JQ, Leav I and Crane PD: The interaction among glucose transport, hexokinase, and glucose-6-phosphatase with respect to 3H-2-deoxyglucose retention in murine tumor models. Nucl Med Biol 23: 533-541, 1996.
-
(1996)
Nucl Med Biol
, vol.23
, pp. 533-541
-
-
Nelson, C.A.1
Wang, J.Q.2
Leav, I.3
Crane, P.D.4
-
22
-
-
33751173430
-
Altered gene expression induced by ionizing radiation and glycolytic inhibitor 2-deoxy-glucose in a human glioma cell line: Implications for radio sensitization
-
Heminger K, Jain V, Kadakia M, Dwarakanath B and Berberich SJ: Altered gene expression induced by ionizing radiation and glycolytic inhibitor 2-deoxy-glucose in a human glioma cell line: implications for radio sensitization. Cancer Biol Ther 5: 815-823, 2006.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 815-823
-
-
Heminger, K.1
Jain, V.2
Kadakia, M.3
Dwarakanath, B.4
Berberich, S.J.5
-
23
-
-
0030603101
-
2+ and reactive oxygen intermediates as messengers
-
2+ and reactive oxygen intermediates as messengers. FEBS Lett 392: 129-136, 1996.
-
(1996)
FEBS Lett
, vol.392
, pp. 129-136
-
-
Pahl, H.L.1
Baeuerle, P.A.2
-
24
-
-
0038407274
-
2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism
-
Lin X, Zhang F, Bradbury CM, et al: 2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism. Cancer Res 63: 3413-3417, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 3413-3417
-
-
Lin, X.1
Zhang, F.2
Bradbury, C.M.3
-
25
-
-
38149063508
-
2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer
-
Coleman MC, Asbury CR, Daniels D, et al: 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer. Free Radic Biol Med 44: 322-331, 2008.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 322-331
-
-
Coleman, M.C.1
Asbury, C.R.2
Daniels, D.3
-
26
-
-
34248142302
-
2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells
-
Simons AL, Ahmad IM, Mattson DM, Dornfeld KJ and Spitz DR: 2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells. Cancer Res 67: 3364-3370, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 3364-3370
-
-
Simons, A.L.1
Ahmad, I.M.2
Mattson, D.M.3
Dornfeld, K.J.4
Spitz, D.R.5
-
27
-
-
1642494855
-
2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo
-
Maschek G, Savaraj N, Priebe W, et al: 2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo. Cancer Res 64: 31-34, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 31-34
-
-
Maschek, G.1
Savaraj, N.2
Priebe, W.3
-
28
-
-
0035879414
-
Heterogeneity in 2-deoxy-D-glucose-induced modifications in energetics and radiation responses of human tumor cell lines
-
Dwarkanath BS, Zolzer F, Chandana S, et al: Heterogeneity in 2-deoxy-D-glucose-induced modifications in energetics and radiation responses of human tumor cell lines. Int J Radiat Oncol Biol Phys 50: 1051-1061, 2001.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.50
, pp. 1051-1061
-
-
Dwarkanath, B.S.1
Zolzer, F.2
Chandana, S.3
-
29
-
-
0027476668
-
Reversibility of inhibition of DNA double strand break repair by 2-deoxy-D-glucose in Ehrlich ascites tumour cells
-
Jha B and Pohlit W: Reversibility of inhibition of DNA double strand break repair by 2-deoxy-D-glucose in Ehrlich ascites tumour cells. Int J Radiat Biol 63: 459-467, 1993.
-
(1993)
Int J Radiat Biol
, vol.63
, pp. 459-467
-
-
Jha, B.1
Pohlit, W.2
-
30
-
-
0030009250
-
Improving cancer radiotherapy with 2-deoxy-D-glucose: Phase I/II clinical trials on human cerebral gliomas
-
Mohanti BK, Rath GK, Anantha N, et al: Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trials on human cerebral gliomas. Int J Radiat Oncol Biol Phys 35: 103-111, 1996.
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.35
, pp. 103-111
-
-
Mohanti, B.K.1
Rath, G.K.2
Anantha, N.3
-
31
-
-
34249681337
-
-
Bensaad K and Vousden KH: p53: new roles in metabolism. Trends Cell Biol 17: 286-291, 2007.
-
Bensaad K and Vousden KH: p53: new roles in metabolism. Trends Cell Biol 17: 286-291, 2007.
-
-
-
-
32
-
-
20844449238
-
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
-
Jones RG, Plas DR, Kubek S, et al: AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 18: 283-293, 2005.
-
(2005)
Mol Cell
, vol.18
, pp. 283-293
-
-
Jones, R.G.1
Plas, D.R.2
Kubek, S.3
-
33
-
-
33745149291
-
p53 regulates mitochondrial respiration
-
Matoba S, Kang JG, Patino WD, et al: p53 regulates mitochondrial respiration. Science 312: 1650-1653, 2006.
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
-
34
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
Kondoh H, Lleonart ME, Gil J, et al: Glycolytic enzymes can modulate cellular life span. Cancer Res 65: 177-185, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
-
35
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
Bensaad K, Tsuruta A, Selak MA, et al: TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126: 107-120, 2006.
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
-
36
-
-
39149111234
-
2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress
-
Ahmad IM, Abdalla MY, Aykin-Burns N, et al: 2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress. Free Radic Biol Med 44: 826-834, 2008.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 826-834
-
-
Ahmad, I.M.1
Abdalla, M.Y.2
Aykin-Burns, N.3
-
37
-
-
43049139541
-
p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation
-
Kawauchi K, Araki K, Tobiume K and Tanaka N: p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation. Nat Cell Biol 10: 611-618, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 611-618
-
-
Kawauchi, K.1
Araki, K.2
Tobiume, K.3
Tanaka, N.4
-
38
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor
-
Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE and Chumakov PM: The antioxidant function of the p53 tumor suppressor. Nat Med 11: 1306-1313, 2005.
-
(2005)
Nat Med
, vol.11
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
40
-
-
35449002129
-
Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging
-
Simons AL, Fath MA, Mattson DM, et al: Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging. Int J Radiat Oncol Biol Phys 69: 1222-1230, 2007.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.69
, pp. 1222-1230
-
-
Simons, A.L.1
Fath, M.A.2
Mattson, D.M.3
|