Oxidative stress as a significant factor for development of an adaptive response in irradiated and nonirradiated human lymphocytes after inducing the bystander effect by low-dose X-radiation

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 669, Issue 1-2, 2009, Pages 155-161

  Ermakov, Aleksei V ^a   Konkova, Marina S ^a   Kostyuk, Svetlana V ^a   Egolina, Natalya A ^a   Efremova, Liudmila V ^a   Veiko, Natalya N ^a  

^a RESEARCH CENTRE FOR MEDICAL GENETICS   (Russian Federation)

Author keywords

Adaptive response; Bystander effect; Extracellular DNA; Human lymphocytes; Low dose X radiation; Oxidative stress

Indexed keywords

CASPASE 3; DNA FRAGMENT; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 9;

APOPTOSIS; ARTICLE; BYSTANDER EFFECT; CONTROLLED STUDY; HUMAN; HUMAN CELL; IONIZING RADIATION; LYMPHOCYTE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN INTERACTION; RADIATION DOSE; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; X IRRADIATION;

APOPTOSIS; BYSTANDER EFFECT; CASPASE 3; CELLS, CULTURED; DNA; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; HYDROGEN PEROXIDE; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOCYTES; OXIDANTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TOLL-LIKE RECEPTOR 9; X-RAYS;

EID: 70349148218     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2009.06.005     Document Type: Article

References (53)

1. Nagasawa H., and Little J.B. Induction of sister chromatid exchanges by extremely low doses of alpha-particles. Cancer Res. 52 (1992) 6394-6396
2. Azzam E.I., de Toledo S.M., and Little J.B. Stress signaling from irradiated to non-irradiated cells. Cur. Cancer Drug Targets 4 (2004) 53-64
3. Bystander effects and the dose response. Belle News-letter. Biological effects of low level exposure. 11 (2003) p. 36.
4. Iyer R., and Lehnert B.E. Low dose, low-LET ionizing radiation-induced radioadaptation and associated early responses in unirradiated cells. Mutat. Res. 503 (2002) 1-9
5. 3H 10T(1/2) cells. Int. J. Radiat. Biol. 80 (2004) 465-472
6. Scott B.R. A biological-based model that links genomic instability, bystander effects, and adaptive response. Mutat. Res. 568 (2004) 129-143
7. Azzam E.I., de Toledo S.M., Gooding T., and Little J.B. Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles. Radiat. Res. 150 (1998) 497-504
8. Wu L.J., Randers-Pehrson G., Xu A., Waldren C.A., Geard C.R., Yu Z., and Hei T.K. Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 4959-4964
9. Shao C., Folkard M., Michael B.D., and Prise K.M. Targeted cytoplasmic irradiation induces bystander responses. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 13495-13500
10. Freeman S.M., Abboud C.N., Whartenby K.A., Packman C.H., Koeplin D.S., Moolten F.L., and Abraham G.N. The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res. 53 (1993) 5274-5283
11. Mothersill C., Stamato T.D., Perez M.L., Cummins R., Mooney R., and Seymour C.B. Involvement of energy metabolism in the production of 'bystander effects' by radiation. Br. J. Cancer 82 (2000) 1740-1746
12. Seymour C.B., Mothersill C., Mooney R., Moriarty M., and Tipton K.F. Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity. Br. J. Cancer 89 (2003) 1979-1986
13. Ermakov A.V., Kostyuk S.V., Konkova M.S., Egolina N.A., Malinovskaya E.M., and Veiko N.N. Factors of stress signaling between X-irradiated and nonirradiated human lymphocytes. Ann. N.Y. Acad. Sci. 1137 (2008) 41-46
14. Wang Z., and Zhou Y. Effects of sodium salicylate on the expression of HSP27 protein during oxidative stress in tissue-cultured human lens epithelial cells. J. Huazhong. Univ. Sci. Technol. Med. Sci. 26 (2006) 753-755
15. Yaung J., Jin M., Barron E., Speed C., Wawrousek E.F., Kannan R., and Hinton D.R. Alpha-crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress. Mol. Vis. 13 (2007) 566-577
16. ApoAlert™CPP32/Caspase 3 Proteas assay Kits. CLONTECHniques XII (1997) pp. 4-6.
17. Casciola-Rosen L.A., Nicholson D.W., Chong T., Rowan K.R., Thornberry N.A., Miller D.K., and Rosen A. Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. J. Exp. Med. 183 (1996) 1957-1964
18. 0-lymphocytes. Radiat. Biol. Radioecol. 44 (2004) 501-508
19. Ji L.L., Gomez-Cabrera M.C., and Vina J. Exercise and hormesis: activation of cellular antioxidant signaling pathway. Ann. N.Y. Acad. Sci. 1067 (2006) 425-435
20. Lehnert B.E., and Iyer R. Exposure to low-level chemicals and ionizing radiation: reactive oxygen species and cellular pathways. Hum. Exp. Toxicol. 21 (2002) 65-69
21. Jeong S.J., Jin Y.H., Moon C.W., Bae H.R., Yoo Y.H., Lee H.S., Lee S.H., Lim Y.J., Lee J.D., and Jeong M.H. Protein tyrosine kinase inhibitors modulate radiosensitivity and radiation-induced apoptosis in K562 cells. Radiat. Res. 156 (2001) 751-760
22. Nakajima T. Signaling cascades in radiation-induced apoptosis: roles of protein kinase C in the apoptosis regulation. Med. Sci. Monit. 12 (2006) 220-224
23. Hallahan D.E., Virudachalam S., Sherman M.L., Huberman E., Kufe D.W., and Weichselbaum R.R. Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation. Cancer Res. 51 (1991) 4565-4569
24. Kuwabara M., Takahashi K., and Inanami O. Induction of apoptosis through the activation of SAPK/JNK followed by the expression of death receptor Fas in X-irradiated cells. J. Radiat. Res. 44 (2003) 203-209
25. Nakano H., and Shinohara K. Time sequence analysis of caspase-3-independent programmed cell death and apoptosis in X-irradiated human leukemic MOLT-4 cells. Cell Tissue Res. 310 (2002) 305-311
26. Haimovitz-Friedman A., Kan C.C., Ehleiter D., Persaud R.S., McLoughlin M., Fuks Z., and Kolesnick R.N. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J. Exp. Med. 180 (1994) 525-535
27. Verheij M., van Blitterswijk W., and Bartelink H. Radiation-induced apoptosis-the ceramide-SAPK signaling pathway and clinical aspects. Acta Oncol. 37 (1998) 575-581
28. Verheij M., Bose R., Lin X.N., Yao B., Jarvis W.D., Grant S., Birrer M.J., Szabo E., Zon L.I., Kyriakis J.M., Haimovitz-Friedman A., Fuks Z., and Kolesnick R.N. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 380 (1996) 75-79
29. Taneja N., Tjalkens R., Philbert M.A., and Rehemtulla A. Irradiation of mitochondria initiates apoptosis in a cell free system. Oncogene 20 (2001) 167-177
30. Hamasu T., Inanami O., Asanuma T., and Kuwabara M. Enhanced induction of apoptosis by combined treatment of human carcinoma cells with X rays and death receptor agonists. J. Radiat. Res. 46 (2005) 103-110
31. Anker P., Strong M., and Maurice P.A. Spontaneous release of DNA by human blood lymphocytes as shown in vitro system. Cancer Res. 35 (1975) 2375-2382
32. 3H]-thymidine incorporation by mouse spleen lymphocytes. Cell Biochem. Funct. 15 (1997) 119-126
33. Miura M., Chen X.D., Allen M.R., Bi Y., Gronthos S., Seo B.M., Lakhani S., Flavell R.A., Feng X.H., Robey P.G., Young M., and Shi S. A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells. J. Clin. Invest. 114 (2004) 1704-1713
34. Lyng F.M., Seymour C.B., and Mothersill C. Early events in the apoptotic cascade initiated in cells treated with medium from the progeny of irradiated cells. Radiat. Prot. Dosim. 99 (2002) 169-172
35. Lehnert B.E., Goodwin E.H., and Deshpande A. Extracellular factor(s) following exposure to alpha particles can cause sister chromatid exchanges in normal human cells. Cancer Res. 57 (1997) 2164-2171
36. Narayanan P.K., Goodwin E.H., and Lehnert B.E. Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells. Cancer Res. 57 (1997) 3963-3971
37. Iyer R., Lehnert B.E., and Svensson R. Factors underlying the cell growth-related bystander responses to alpha particles. Cancer Res. 60 (2000) 1290-1298
38. Lyng F.M., Seymour C.B., and Mothersill C. Initiation of apoptosis in cells exposed to medium from the progeny of irradiated cells: a possible mechanism for bystander-induced genomic instability?. Radiat. Res. 157 (2002) 365-370
39. Khan M.A., van Dyk I., Yeung W., and Hill R.P. Partial volume rat lung irradiation; assessment of early DNA damage in different lung regions and effect of radical scavengers. Radiother. Oncol. 66 (2003) 95-102
40. Dalpke A.H., Schafer M.K., Zimmermann S., Tebbe J., Weihe E., and Heeg K. Immunostimulatory CpG-DNA activates murine microglia. J. Immunol. 168 (2002) 4854-4863
41. Jozsef L., Khreiss T., El Kebir D., and Filep J.G. Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. J. Immunol. 176 (2006) 1195-1202
42. Pedras-Vasconcelos J.A., Goucher D., Puig M., Tonelli L.H., Wang V., Ito S., and Verthelyi D. CpG oligodeoxynucleotides protect newborn mice from a lethal challenge with the neurotropic Tacaribe arenavirus. J. Immunol. 176 (2006) 4940-4949
43. Franchini M., Schweizer M., Mätzener P., Magkouras I., Sauter K.S., Mirkovitch J., Paterhans E., and Jungi T.W. Evidence for dissociation of TLR mRNA expression and TLR agonist-mediated functions in bovine macrophages. Vet. Immunol. Immunopathol. 110 (2006) 37-49
44. Henneke P., Takeuchi O., Malley R., Lien E., Ingalls R.R., Freeman M.W., Mayadas T., Nizet V., Akira S., Kasper D.L., and Golenbock D.T. Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways. J. Immunol. 169 (2002) 3970-3977
45. Adachi Y., Kindzelskii A., Petty A.R., Huang J.B., Maeda N., Yotsumoto S., Aratani Y., Ohno N., and Petty H.R. IFN-gamma primes RAW264 macrophages and human monocytes for enhanced oxidant production in response to CpG DNA via metabolic signaling: roles of TLR9 and myeloperoxidase trafficking. J. Immunol. 176 (2006) 5033-5040
46. Matsumoto H., Hamada N., Takahashi A., Kobayashi Y., and Ohnishi T. Vanguards of paradigm shift in radiation biology: radiation-induced adaptive and bystander responses. J. Radiat. Res. 48 (2007) 97-106
47. Matsumoto H., Takahashi A., and Ohnishi T. Radiation-induced adaptive responses and bystander effects. Biol. Sci. Space 18 (2004) 247-254
48. Yasuda K., Yu P., Kirschning C.J., Schlatter B., Schmitz F., Heat A., Bauer S., Hochrein H., and Wagner H. Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways. J. Immunol. 174 (2005) 6129-6136
49. Wagner H., and Bauer S. All is not Toll: new pathways in DNA recognition. J. Exp. Med. 203 (2006) 265-268
50. Chaudhry M.A. Bystander effect: biological endpoints and microarray analysis. Mutat. Res. 597 (2006) 98-112
51. Veiko N.N., Shubaeva N.O., Ivanova S.M., Speranskii A.I., Lyapunova N.A., and Spitkovskii D.M. Blood serum DNA in patients with rheumatoid arthritis is considerably enriched with fragments of ribosomal repeats containing immunostimulatory CpG-motifs. Bull. Exp. Biol. Med. 142 (2006) 313-316
52. Veiko N.N., Kalashnikova E.A., Kokarovtseva S.N., Kostyuk S.V., Ermakov A.V., Ivanova S.M., Ryazantseva T.A., Egolina N.A., Lyapunova N.A., and Spitkovskii D.M. Stimulatory effect of fragments from transcribed region of ribosomal repeat on human peripheral blood lymphocytes. Bull. Exp. Biol. Med. 142 (2006) 428-432
53. Collins L.V., Hajizaden S., Holme E., Jonsson I.M., and Tarkowski A. Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses. J. Leukoc. Biol. 75 (2004) 995-1000