Partial volume rat lung irradiation; Assessment of early DNA damage in different lung regions and effect of radical scavengers

Radiotherapy and Oncology

Volumn 66, Issue 1, 2003, Pages 95-102

  Khan, Mohammed A ^a,b   Van Dyk, Jake ^c,d   Yeung, Ivan W T ^a   Hill, Richard P ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c LONDON REGIONAL CANCER PROGRAM   (Canada)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

DNA effects; Micronucleus assay; Nitro L arginine methyl ester; Partial volume effects; Radiation induced lung damage; Rat lung cells; Superoxide dismutase

Indexed keywords

COBALT 60; CYTOKINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COBALT THERAPY; CONTROLLED STUDY; DNA DAMAGE; FEMALE; FIBROBLAST; IRRADIATION; LUNG; LUNG VOLUME; MICRONUCLEUS TEST; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION PROTECTION; RAT;

EID: 12244289275     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-8140(02)00325-0     Document Type: Article

References (52)

1. Anscher M.S., Kong F.M., Marks L.B., Bentel G.C., Jirtle R.L. Changes in plasma transforming growth factor beta during radiotherapy and the risk of symptomatic radiation-induced pneumonitis. Int J Radiat Oncol Biol Phys. 37:1997;253-258.
2. Bao S., Harwood P.W., Wood B.H., Chrisler W.B., Groch K.M., Brooks A.L. Comparative clastogenic sensitivity of respiratory tract cells to gamma rays. Radiat Res. 148:1997;90-97.
3. Baumann M., Appold S., Geyer P., Knorr A., Voigtmann L., Herrmann T. Lack of effect of small high-dose volumes on the dose-response relationship for the development of fibrosis in distant parts of the ipsilateral lung in mini pigs. Int J Radiat Biol. 76:2000;477-486.
4. Breuer R., Tochner Z., Conner M.W., et al. Superoxide dismutase inhibits radiation-induced lung injury in hamsters. Lung. 170:1992;19-29.
5. Dileto C.L., Travis E.L. Fibroblast radiosensitivity in vitro and lung fibrosis in vivo: comparison between a fibrosis-prone and fibrosis-resistant mouse strain. Radiat Res. 146:1996;61-67.
6. Emami B., Lyman J.T., Brown A., et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys. 21:1991;109-122.
7. Emerit I., Khan S.H., Cerutti P. Treatment of lymphocyte cultures with a hypoxanthine oxidase system induces the formation of transferable clastogenic material. Free Radic Biol Med. 1:1985;51-57.
8. Emerit I., Levy A., Pagano G., Pinto L., Calzone R., Zatterale A. Transferable clastogenic activity in plasma from patients with Fanconi anemia. Hum Genet. 96:1995;14-20.
9. Epperly E.W., Bray J.A., Krager S., et al. Intratracheal injection of adenovirus containing the human MnSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis. Int J Radiat Oncol Biol Phys. 43:1999;169-181.
10. Epperly M.W., Epstein C.J., Travis E.L., Greenberger J.S. Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnSOD)-deficient mice is corrected by human manganese superoxide dismutase-plasmodia/liposome (SOD2-PL) intratracheal gene therapy. Radiat Res. 154:2000;365-374.
11. Epperly M.W., Travis E.L., Whitsett J.A., Raineri I., Epstein C.J., Greenberger J.S. Overexpression of manganese superoxide dismutase (MnSOD) in whole lung or alveolar type II cells of MnSOD transgenic mice does not provide intrinsic lung irradiation protection. Int J Cancer. 96:2001;11-21.
12. Felley-Bosco E. Role of nitric oxide in genotoxicity: implication for carcinogenesis. Cancer Metastasis Rev. 17:1998;25-37.
13. Franko A.J., Sharplin J., Gahary A., Barcellos-Hoff M.H. Immunohistochemical localization of transforming growth factor beta and tumor necrosis factor alpha in the lungs of fibrosis-prone and 'non-fibrosing' mice during the latent period and early phase after irradiation. Radiat Res. 147:1997;245-256.
14. Franko A.J., Sharplin J., Ward W.F., Hinz J.M. The genetic basis of strain-dependent differences in the early phase of radiation injury in mouse lung. Radiat Res. 126:1991;349-356.
15. Fuks Z., Persaud R.S., Alfieri A., et al. Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo. Cancer Res. 54:1994;2582-2590.
16. Hallahan D.E., Spriggs D.R., Beckett M.A., Kufe D.W., Weichselbaum R.R. Increased tumor necrosis factor after exposure to ionizing radiation. Proc Natl Acad Sci USA. 86:1989;10104-10107.
17. Hallahan D.E., Virudachalam S. Intercellular adhesion molecule 1 knockout abrogates radiation-induced pulmonary inflammation. Proc Natl Acad Sci USA. 94:1997;6432-6437.
18. Haston C.K., Travis E.L. Murine susceptibility to radiation-induced pulmonary fibrosis is induced by a genetic factor implicated in susceptibility to bleomycin-induced pulmonary fibrosis. Cancer Res. 57:1997;5286-5291.
19. Hill R.P., Rodemann H., Hendry J.H., Roberts S.A., Anscher M.S. Normal tissue radiobiology: from the laboratory to the clinic. Int J Radiat Oncol Biol Phys. 49:2001;353-365.
20. Hong J.H., Chiang C.S., Tsao C.Y., Lin P.Y., McBride W.H., Wu C.J. Rapid induction of cytokine gene expression in the lung after single and fractionated doses of radiation. Int J Radiat Biol. 75:1999;1421-1427.
21. Johnston C.J., Piedboeuf B., Rubin P., Williams J.P., Baggs R., Finkelstein J.N. Early and persistent alterations in the expression of interleukin-1 alpha, Interleukin-1 beta and tumour necrosis factor- alpha mRNA levels in fibrosis-resistant and sensitive mice after thoracic irradiation. Radiat Res. 145:1996;762-767.
22. Johnston C.J., Wright T.W., Rubin P., Finkelstein J.N. Alterations in the expression of chemokine mRNA levels in fibrosis-resistant and -sensitive mice after thoracic irradiation. Exp Lung Res. 24:1998;321-337.
23. Kallman P., Lind B.K., Brahme A. An algorithm for maximizing the probability of complication-free tumour control in radiation therapy. Phys Med Biol. 37:1992;871-890.
24. Khan M.A., Cross F.T., Jostes R., Hui E., Morris J.E., Brooks A.L. Micronuclei induced by radon and its progeny in deep-lung fibroblasts of rats in vivo and in vitro. Radiat Res. 139:1994;53-59.
25. Khan M.A., Heddle J.A. Chemical induction of somatic gene mutation and chromosomal aberrations in rats. Mutat Res. 263:1991;257-262.
26. Khan M.A., Hill R.P., Van Dyk J. Partial volume rat lung irradiation: an evaluation of early DNA damage. Int J Radiat Oncol Biol Phys. 40:1998;467-476.
27. Liao Z.X., Travis E.L., Tucker S.L. Damage and morbidity from pneumonitis after irradiation of partial volumes of mouse lung. Int J Radiat Oncol Biol Phys. 32:1995;1359-1370.
28. Lyman J.T., Wolbarst A.B. Optimization of radiation therapy, III: a method of assessing complication probability from dose-volume histograms. Int J Radiat Oncol Biol Phys. 13:1987;103-109.
29. Mah K., Van Dyk J., Keane T.J., Poon P.Y. Acute radiation-induced pulmonary damage: a clinical study on the response to fractionated radiation therapy. Int J Radiat Oncol Biol Phys. 13:1987;179-188.
30. Milligan J.R., Ng J.Y., Wu C.C., et al. Methylperoxyl radicals as intermediates in the damage to DNA irradiated in aqueous dimethyl sulfoxide with gamma rays. Radiat Res. 146:1996;436-443.
31. Moiseenko V.V., Battista J.J., Hill R.P., Travis E.L., Van Dyk J. In-field and out-of-field effects in partial volume lung irradiation in rodents: Possible correlation between early DNA damage and functional endpoints. Int J Radiat Oncol Biol Phys. 48:2000;1539-1543.
32. Morgan G.W., Breit S.N. Radiation and the lung: a re-evaluation of the mechanisms mediating pulmonary injury. Int J Radiat Oncol Biol Phys. 31:1995;361-369.
33. Nakayama Y., Makino S., Fakuda Y., Min K.Y., Shimizu A., Ohsawa N. Activation of lavage lymphocytes in lung injuries caused by radiotherapy for lung cancer. Int J Radiat Oncol Biol Phys. 34:1996;459-467.
34. Niemierko A., Goitein M. Modeling of normal tissue response to radiation: the critical volume model. Int J Radiat Oncol Biol Phys. 25:1992;135-145.
35. Nozaki Y., Hasegawa Y., Takeuchi A., et al. Nitric oxide as an inflammatory mediator of radiation pneumonitis in rats. Am J Physiol. 272:1997;L651-L658.
36. Parizada B., Weber M.M., Nimrod A. Protective effect of human recombinant MnSOD in adjuvant arthritis and bleomycin-induced lung fibrosis. Free Radic Res Comms. 15:1991;297-301.
37. Phillips T.L., Wara M.D., Margolis L.W. Modification of radiation injury to normal tissue by chemotherapeutic agents. Cancer. 35:1975;1678-1684.
38. Rubin P. Late effects of chemotherapy and radiation therapy: a new hypothesis. Int J Radiat Oncol Biol Phys. 10:1984;5-34.
39. Rubin P., Johnston C.J., Williams J.P., McDonald S., Finkelstein J.N. A perpetual cascade of cytokines post-irradiation leads to pulmonary fibrosis. Int J Radiat Oncol Biol Phys. 33:1995;99-109.
40. Shaw R.J., Benedict S.H., Clark R.A.F., et al. Pathogenesis of pulmonary fibrosis in interstitial lung disease - Alveolar macrophage PDGF(B) gene activation and upregulation by interferon gamma. Am Rev Respir Dis. 143:1991;167-173.
41. Shepherd V.L. Cytokine receptors of the lung. Am J Respir Cell Mol Biol. 5:1991;403-410.
42. Siemann D.W., Hill R.P., Penney D.P. Early and late pulmonary toxicity in mice evaluated 180 and 420 days following localized lung irradiation. Radiat Res. 89:1982;396-407.
43. Tamir S., de Rojas-Walker T., Wishnok J.S., Tannenbaum S.R. DNA damage and genotoxicity by nitric oxide. Methods Enzymol. 269:1996;230-243.
44. Tee P.G., Travis E.L. Basic fibroblast growth factor does not protect against classical radiation pneumonitis in two strains of mice. Cancer Res. 55:1995;298-302.
45. Travis E.L. Organizational response of normal tissues to irradiation. Semin Radiat Oncol. 11:2001;184-196.
46. Travis E.L., Down J.D., Holmes S.J., Hobson B. Radiation pneumonitis and fibrosis in mouse lung assayed by respiratory frequency and histology. Radiat Res. 84:1980;133-143.
47. Travis E.L., Liao Z.X., Tucker S.L. Spatial heterogeneity of the volume effect for radiation pneumonitis in mouse lung. Int J Radiat Oncol Biol Phys. 38:1997;1045-1054.
48. Travis E.L., Tucker S.L. The relationship between functional assays of radiation response in the lung and target cell depletion. Br J Cancer. (Suppl VII):1986;304-319.
49. Trott K.-R., Kamprad F. Radiobiological mechanisms of anti-inflammatory radiotherapy. Radiother Oncol. 51:1999;197-203.
50. Tucker S.L., Liao Z.X., Travis E.L. Estimation of the spatial distribution of target cells for radiation pneumonitis in mouse lung. Int J Radiat Oncol Biol Phys. 38:1997;1055-1066.
51. Van Dyk J., Keane T.J., Kan S., Rider W.D., Fryer C.J. Radiation pneumonitis following large single dose irradiation: a re-evaluation based on absolute dose to lung. Int J Radiat Oncol Biol Phys. 7:1981;461-467.
52. Withers H.R., Taylor J.M.G., Maciejewski B. Treatment volume and tissue tolerance. Int J Radiat Oncol Biol Phys. 14:1988;751-759.