Engraftment of syngeneic and allogeneic endothelial cells, hepatocytes and cholangiocytes into partially hepatectomized rats previously treated with mitomycin c

Transplantation

Volumn 88, Issue 4, 2009, Pages 486-495

  Brilliant, Kate E ^a,b   Mills, David R ^a,b   Callanan, Helen M ^a,b   Hixson, Douglas C ^a,b  

^a RHODE ISLAND HOSPITAL   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Mitomycin C, Partial hepatectomy, Rat, Dipeptidyl peptidase IV, Histochemical stain

Indexed keywords

BIOCHEMICAL MARKER; CD3 ANTIBODY; CELL MEMBRANE PROTEIN; CYTOSOL AMINOPEPTIDASE; DIPEPTIDYL PEPTIDASE IV; GENTAMICIN; MITOMYCIN C; RECA 1 PROTEIN; RETRORSINE; UNCLASSIFIED DRUG;

AGE DISTRIBUTION; ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CHOLANGIOCYTE; COLONY FORMATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; FETUS; HEPATOCYTE TRANSPLANTATION; IMMUNOSUPPRESSIVE TREATMENT; ISOLATED LIVER; LIVER CELL; LIVER CELL CULTURE; LIVER REGENERATION; LIVER SINUSOID; MORTALITY; NEWBORN; NONHUMAN; PARTIAL HEPATECTOMY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SURVIVAL; WEIGHT GAIN;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD26; BILE DUCTS; CELL DIFFERENTIATION; CELL PROLIFERATION; ENDOTHELIAL CELLS; FEMALE; GRAFT ENHANCEMENT, IMMUNOLOGIC; HEPATECTOMY; HEPATOCYTES; LIVER REGENERATION; MITOMYCIN; PREGNANCY; PYRROLIZIDINE ALKALOIDS; RATS; RATS, INBRED ACI; RATS, INBRED F344; RATS, MUTANT STRAINS; TRANSPLANTATION, HOMOLOGOUS; TRANSPLANTATION, ISOGENEIC;

EID: 70349133552     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3181b0b98a     Document Type: Article

References (60)

1. Thompson NL, Hixson DC, Callanan H, et al. A Fischer rat substrain deficient in dipeptidyl peptidase IV activity makes normal steady-state RNA levels and an altered protein. Use as a liver-cell transplantation model. Biochem J 1991; 273 (Pt 3): 497.
2. Sigal SH, Rajvanshi P, Reid LM, et al. Demonstration of differentiation in hepatocyte progenitor cells using dipeptidyl peptidase IV deficient mutant rats. Cell Mol Biol Res 1995; 41: 39.
3. Coleman WB, McCullough KD, Esch GL, et al. Evaluation of the differentiation potential of WB-F344 rat liver epithelial stem-like cells in vivo. Differentiation to hepatocytes after transplantation into dipeptidylpeptidase-IV-deficient rat liver. Am J Pathol 1997; 151: 353.
4. Hixson DC. Animal models for assessing the contribution of stem cells to liver development. In: Sell S, ed. Stem cell handbook. Towanda, NJ, Humana Press 2003, p 353.
5. Laconi S, Curreli F, Diana S, et al. Liver regeneration in response to partial hepatectomy in rats treated with retrorsine: A kinetic study. J Hepatol 1999; 31: 1069.
6. Simper-Ronan R, Brilliant K, Flanagan D, et al. Cholangiocyte marker-positive and -negative fetal liver cells differ significantly in their ability to regenerate the livers of adult rats exposed to retrorsine. Development 2006; 133: 4269.
7. Fu PP, Xia Q, Lin G, et al. Pyrrolizidine alkaloids-Genotoxicity, metabolism enzymes, metabolic activation, and mechanisms. Drug Metab Rev 2004; 36: 1.
8. Yang L, Faris RA, Hixson DC. Long-term culture and characteristics of normal rat liver bile duct epithelial cells. Gastroenterology 1993; 104: 840.
9. Higgins GM, Anderson RM. Experimental pathology of the liver. I. Restoration of the liver of the white rat following surgical removal. Arch Pathol 1931; 12: 186.
10. Piazza GA, Callanan HM, Mowery J, et al. Evidence for a role of dipep-tidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix. Biochem J 1989; 262: 327.
11. Erickson BM, Thompson NL, Hixson DC. Tightly regulated induction of the adhesion molecule necl-5/CD155 during rat liver regeneration and acute liver injury. Hepatology 2006; 43: 325.
12. Comegys MM, Carreiro MP, Brown JF, et al. C-CAM1 expression: Differential effects on morphology, differentiation state and suppression of human PC-3 prostate carcinoma cells. Oncogene 1999; 18: 3261.
13. Hixson DC, Brown J, McBride AC, et al. Differentiation status of rat ductal cells and ethionine-induced hepatic carcinomas defined with surface-reactive monoclonal antibodies. Exp Mol Pathol 2000; 68: 152.
14. Mowery J, Hixson DC. Detection of cell-CAM 105 in the pericanalicu-lar domain of the rat hepatocyte plasma membrane. Hepatology 1991; 13: 47.
15. Gordon GJ, Coleman WB, Grisham JW. Induction of cytochrome P450 enzymes in the livers of rats treated with the pyrrolizidine alkaloid retrorsine. Exp Mol Pathol 2000; 69: 17.
16. Britt DE, Yang DF, Yang DQ, et al. Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells. Exp Cell Res 2004; 300: 134.
17. Faris RA, McEntire KD, Thompson NL, et al. Identification and characterization of a rat hepatic oncofetal membrane glycoprotein. Cancer Res 1990; 50: 4755.
18. Duijvestijn AM, van Goor H, Klatter F, et al. Antibodies defining rat endothelial cells: RECA-1, a pan-endothelial cell-specific monoclonal antibody. Lab Invest 1992; 66: 459.
19. Hendzel MJ, Wei Y, Mancini MA, et al. Mitosis-specific phosphoryla-tion of histone H3 initiates primarily within pericentromeric hetero-chromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma 1997; 106: 348.
20. Molyneux G, Gibson FM, Gordon-Smith EC, et al. The haemotoxicity of mitomycin in a repeat dose study in the female CD-1 mouse. Int J Exp Pathol 2005; 86: 415.
21. Matsumoto K, Furuya T, Tobe M. Effect of mitomycin C on bone marrow cells in mice. J Toxicol Sci 1984; 9: 51.
22. Futamura Y, Matsumoto K. Characteristics of peripheral blood mono-cytes and bone marrow macrophages from rats treated with mitomycin C, 5-fluorouracil or phenylhydrazine. J Toxicol Sci 1995; 20: 1.
23. Cassell GH, Davis JK, Lindsey JR. Control of Mycoplasma pulmonis infection in rats and mice: Detection and elimination vs. vaccination. Isr J Med Sci 1981; 17: 674.
24. Baker DG. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev 1998; 11: 231.
25. Rottem S. Interaction of mycoplasmas with host cells. Physiol Rev 2003; 83: 417.
26. Karen GRC. A layman's guide to the health and nursing care of rats. Westminister, CA, RMCA 2000. Available at: http://ratguide.com/ health/. Accessed June 30, 2009.
27. Gupta S, Rajvanshi P, Malhi H, et al. Cell transplantation causes loss of gap junctions and activates GGT expression permanently in host liver. Am J Physiol Gastrointest Liver Physiol 2000; 279: G815.
28. Hanigan MH, Frierson HF Jr. Immunohistochemical detection of gamma-glutamyl transpeptidase in normal human tissue. J Histochem Cytochem 1996; 44: 1101.
29. Gordon GJ, Coleman WB, Hixson DC, et al. Liver regeneration in rats with retrorsine-induced hepatocellular injury proceeds through a novel cellular response. Am J Pathol 2000; 156: 607.
30. Gordon GJ, Butz GM, Grisham JW, et al. Isolation, short-term culture, and transplantation of small hepatocyte-like progenitor cells from retrorsine-exposed rats. Transplantation 2002; 73: 1236.
31. Cole MS, Stellrecht KE, Shi JD, et al. HuM291, a humanized anti-CD3 antibody, is immunosuppressive to T cells while exhibiting reduced mitogenicity in vitro. Transplantation 1999; 68: 563.
32. Chatenoud L, Thervet E, Primo J, et al. Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc Natl Acad Sci USA 1994; 91: 123.
33. Woodle ES, Hussein S, Bluestone JA. In vivo administration of anti-murine CD3 monoclonal antibody induces selective, long-term anergy in CD8- T cells. Transplantation 1996; 61: 798.
34. Suzuki H, Li XH, Miyamoto M, et al. Induction of transplantation tolerance in adult rats by vascularized spleen transplantation. Transplantation 1997; 64: 650.
35. Inbred and genetically defined strains of laboratory animals. Part 1: Mouse and rat. Bethesda, MD, Federation of American Societies for Experimental Biology 1979, p 418.
36. Wang JJ, Hendrich KS, Jackson EK, et al. Perfusion quantitation in transplanted rat kidney by MRI with arterial spin labeling. Kidney Int 1998; 53: 1783.
37. Foster RD, Pham S, Li S, et al. Long-term acceptance of composite tissue allografts through mixed chimerism and CD28 blockade. Transplantation 2003; 76: 988.
38. Sandhu JS, Petkov PM, Dabeva MD, et al. Stem cell properties and repopulation of the rat liver by fetal liver epithelial progenitor cells. Am J Pathol 2001; 159: 1323.
39. McLean EK. The toxic actions of pyrrolizidine (senecio) alkaloids. Pharmacol Rev 1970; 22: 429.
40. Shah M, Patel K, Sehgal PB. Monocrotaline pyrrole-induced endothe-lial cell megalocytosis involves a Golgi blockade mechanism. Am J Physiol Cell Physiol 2005; 288: C850.
41. MatsumotoK,YoshitomiH,RossantJ,et al.Liverorganogenesispromotedby endothelial cells prior to vascular function. Science 2001; 294: 559.
42. LeCouter J, Moritz DR, Li B, et al. Angiogenesis-independent endothe-lial protection of liver: Role of VEGFR-1. Science 2003; 299: 890.
43. Witek RP, Fisher SH, Petersen BE. Monocrotaline, an alternative to retrorsine-based hepatocyte transplantation in rodents. Cell Transplant 2005; 14: 41.
44. Schultze AE, Roth RA. Chronic pulmonary hypertension-The mono-crotaline model and involvement of the hemostatic system. J Toxicol Environ Health B Crit Rev 1998; 1: 271.
45. Lalich JJ, Merkow L. Pulmonary arteritis produced in rat by feeding Crotalaria spectabilis. Lab Invest 1961; 10: 744.
46. Joseph B, Kumaran V, Berishvili E, et al. Monocrotaline promotes transplanted cell engraftment and advances liver repopulation in rats via liver conditioning. Hepatology 2006; 44: 1411.
47. Lenci G, Muller-Quernheim J, Lorenz J, et al. [Toxic lung damage caused by mitomycin C]. Pneumologie 1994; 48: 197.
48. Cheirsilpa A, Leelasethakul S, Auethaveekiat V, et al. High-dose mito-mycin C: Activity in hepatocellular carcinoma. Cancer Chemother Pharmacol 1989; 24: 50.
49. Okuno SH, Frytak S. Mitomycin lung toxicity. Acute and chronic phases. Am J Clin Oncol 1997; 20: 282.
50. Buzdar AU, Legha SS, Luna MA, et al. Pulmonary toxicity of mitomy-cin. Cancer 1980; 45: 236.
51. Verweij J, Kerpel-Fronius S, Stuurman M, et al. Mitomycin C-induced organ toxicity in Wistar rats: A study with special focus on the kidney. J Cancer Res Clin Oncol 1988; 114: 137.
52. Yan Y, Shastry S, Richards C, et al. Posttransplant administration of donor leukocytes induces long-term acceptance of kidney or liver transplants by an activation-associated immune mechanism. J Immu-nol 2001; 166: 5258.
53. Isaacs JD. T cell immunomodulation-The Holy Grail of therapeutic tolerance. Curr Opin Pharmacol 2007; 7: 418.
54. Rifle G, Mousson C, Herve P. Endothelial cells in organ transplantation: Friends or foes? Transplantation 2006; 82(1 suppl.): S4.
55. Cortesini R, Suciu-Foca N. ILT3-ILT4-tolerogenic endothelial cells in transplantation. Transplantation 2006; 82(1 suppl.): S30.
56. Koopmans M, Kremer HIC, Baelde HJ, et al. Endothelial chimerism in transplantation: Looking for needles in a haystack. Transplantation 2006; 82(1 suppl.): S25.
57. Peichev M, Naiyer AJ, Pereira D, et al. Expression of VEGFR-2 and AC133 by circulating human CD34(-) cells identifies a population of functional endothelial precursors. Blood 2000; 95: 952.
58. Burlingham WJ, Grailer AP, Heisey DM, et al. The effect of tolerance to noninherited maternal HLA antigens on the survival of renal transplants from sibling donors. N Engl J Med 1998; 339: 1657.
59. Aird WC. Endothelium and allotransplantation. Transplantation 2006; 82(1 suppl.): S6.
60. Lagaaij EL, Cramer-Knijnenburg GF, van Kemenade FJ, et al. Endothe-lial cell chimerism after renal transplantation and vascular rejection. Lancet 2001; 357: 33.