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Volumn 389, Issue 1, 2009, Pages 70-73

The ginsenoside Rg3 has a stimulatory effect on insulin signaling in L6 myotubes

Author keywords

Ginsenoside; Insulin signaling; IRS 1; Rg3

Indexed keywords

ADENYLATE KINASE; GINSAM; GINSENG EXTRACT; GINSENOSIDE RG 3; GLUCOSE TRANSPORTER 4; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 70349093060     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.08.088     Document Type: Article
Times cited : (68)

References (21)
  • 1
    • 0035936763 scopus 로고    scopus 로고
    • New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
    • Saltiel A.R. New perspectives into the molecular pathogenesis and treatment of type 2 diabetes. Cell 104 (2001) 517-529
    • (2001) Cell , vol.104 , pp. 517-529
    • Saltiel, A.R.1
  • 2
    • 0031918624 scopus 로고    scopus 로고
    • The IRS-signalling system: a network of docking proteins that mediate insulin action
    • White M.F. The IRS-signalling system: a network of docking proteins that mediate insulin action. Mol. Cell. Biochem. 182 (1998) 3-11
    • (1998) Mol. Cell. Biochem. , vol.182 , pp. 3-11
    • White, M.F.1
  • 3
    • 0042570843 scopus 로고    scopus 로고
    • Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
    • Virkamaki A., Ueki K., and Kahn C.R. Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. J. Clin. Invest. 103 (1999) 931-943
    • (1999) J. Clin. Invest. , vol.103 , pp. 931-943
    • Virkamaki, A.1    Ueki, K.2    Kahn, C.R.3
  • 4
    • 21444460644 scopus 로고    scopus 로고
    • Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes
    • Huang C., Thirone A.C., Huang X., and Klip A. Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes. J. Biol. Chem. 280 (2005) 19426-19435
    • (2005) J. Biol. Chem. , vol.280 , pp. 19426-19435
    • Huang, C.1    Thirone, A.C.2    Huang, X.3    Klip, A.4
  • 6
    • 0033966768 scopus 로고    scopus 로고
    • Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2
    • Kido Y., Burks D.J., Withers D., Bruning J.C., Kahn C.R., White M.F., and Accili D. Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2. J. Clin. Invest. 105 (2000) 199-205
    • (2000) J. Clin. Invest. , vol.105 , pp. 199-205
    • Kido, Y.1    Burks, D.J.2    Withers, D.3    Bruning, J.C.4    Kahn, C.R.5    White, M.F.6    Accili, D.7
  • 7
    • 0033049422 scopus 로고    scopus 로고
    • Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts
    • Wang Q., Somwar R., Bilan P.J., Liu Z., Jin J., Woodgett J.R., and Klip A. Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts. Mol. Cell. Biol. 19 (1999) 4008-4018
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4008-4018
    • Wang, Q.1    Somwar, R.2    Bilan, P.J.3    Liu, Z.4    Jin, J.5    Woodgett, J.R.6    Klip, A.7
  • 9
    • 0030757369 scopus 로고    scopus 로고
    • Panax ginseng pharmacology: a nitric oxide link?
    • Gillis C.N. Panax ginseng pharmacology: a nitric oxide link?. Biochem. Pharmacol. 54 (1997) 1-8
    • (1997) Biochem. Pharmacol. , vol.54 , pp. 1-8
    • Gillis, C.N.1
  • 10
    • 14644402473 scopus 로고    scopus 로고
    • Effect of crude saponin of Korean red ginseng on high-fat diet-induced obesity in the rat
    • Kim J.H., Hahm D.H., Yang D.C., Lee H.J., and Shim I. Effect of crude saponin of Korean red ginseng on high-fat diet-induced obesity in the rat. J. Pharmacol. Sci. 97 (2005) 124-131
    • (2005) J. Pharmacol. Sci. , vol.97 , pp. 124-131
    • Kim, J.H.1    Hahm, D.H.2    Yang, D.C.3    Lee, H.J.4    Shim, I.5
  • 12
    • 16644380244 scopus 로고    scopus 로고
    • Wild ginseng prevents the onset of high-fat diet induced hyperglycemia and obesity in ICR mice
    • Yun S.N., Moon S.J., Ko S.K., Im B.O., and Chung S.H. Wild ginseng prevents the onset of high-fat diet induced hyperglycemia and obesity in ICR mice. Arch. Pharm. Res. 27 (2004) 790-796
    • (2004) Arch. Pharm. Res. , vol.27 , pp. 790-796
    • Yun, S.N.1    Moon, S.J.2    Ko, S.K.3    Im, B.O.4    Chung, S.H.5
  • 13
    • 51349106992 scopus 로고    scopus 로고
    • Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng C A Meyer
    • Choi K.T. Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng C A Meyer. Acta Pharmacol. Sin. 29 (2008) 1109-1118
    • (2008) Acta Pharmacol. Sin. , vol.29 , pp. 1109-1118
    • Choi, K.T.1
  • 14
    • 57049157743 scopus 로고    scopus 로고
    • Effect of ginsam, a vinegar extract from Panax ginseng, on body weight and glucose homeostasis in an obese insulin-resistant rat model
    • Lim S., Yoon J.W., Choi S.H., Cho B.J., Kim J.T., Chang H.S., Park H.S., Park K.S., Lee H.K., Kim Y.B., and Jang H.C. Effect of ginsam, a vinegar extract from Panax ginseng, on body weight and glucose homeostasis in an obese insulin-resistant rat model. Metabolism 58 (2009) 8-15
    • (2009) Metabolism , vol.58 , pp. 8-15
    • Lim, S.1    Yoon, J.W.2    Choi, S.H.3    Cho, B.J.4    Kim, J.T.5    Chang, H.S.6    Park, H.S.7    Park, K.S.8    Lee, H.K.9    Kim, Y.B.10    Jang, H.C.11
  • 15
    • 59449086814 scopus 로고    scopus 로고
    • Antiobesity effect of ginsenoside Rg3 involves the AMPK and PPAR-gamma signal pathways
    • Hwang J.T., Lee M.S., Kim H.J., Sung M.J., Kim H.Y., Kim M.S., and Kwon D.Y. Antiobesity effect of ginsenoside Rg3 involves the AMPK and PPAR-gamma signal pathways. Phytother. Res. 23 (2009) 262-266
    • (2009) Phytother. Res. , vol.23 , pp. 262-266
    • Hwang, J.T.1    Lee, M.S.2    Kim, H.J.3    Sung, M.J.4    Kim, H.Y.5    Kim, M.S.6    Kwon, D.Y.7
  • 16
    • 0032704115 scopus 로고    scopus 로고
    • Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
    • Holmes B.F., Kurth-Kraczek E.J., and Winder W.W. Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. J. Appl. Physiol. 87 (1999) 1990-1995
    • (1999) J. Appl. Physiol. , vol.87 , pp. 1990-1995
    • Holmes, B.F.1    Kurth-Kraczek, E.J.2    Winder, W.W.3
  • 19
    • 0032848778 scopus 로고    scopus 로고
    • Impaired glucose transport and insulin receptor tyrosine phosphorylation in skeletal muscle from obese women with gestational diabetes
    • Friedman J.E., Ishizuka T., Shao J., Huston L., Highman T., and Catalano P. Impaired glucose transport and insulin receptor tyrosine phosphorylation in skeletal muscle from obese women with gestational diabetes. Diabetes 48 (1999) 1807-1814
    • (1999) Diabetes , vol.48 , pp. 1807-1814
    • Friedman, J.E.1    Ishizuka, T.2    Shao, J.3    Huston, L.4    Highman, T.5    Catalano, P.6
  • 20
    • 0035316142 scopus 로고    scopus 로고
    • Insulin resistance with low cellular IRS-1 expression is also associated with low GLUT4 expression and impaired insulin-stimulated glucose transport
    • Carvalho E., Jansson P.A., Nagaev I., Wenthzel A.M., and Smith U. Insulin resistance with low cellular IRS-1 expression is also associated with low GLUT4 expression and impaired insulin-stimulated glucose transport. FASEB J. 15 (2001) 1101-1103
    • (2001) FASEB J. , vol.15 , pp. 1101-1103
    • Carvalho, E.1    Jansson, P.A.2    Nagaev, I.3    Wenthzel, A.M.4    Smith, U.5
  • 21
    • 0033579515 scopus 로고    scopus 로고
    • Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress. Evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathways
    • Blair A.S., Hajduch E., Litherland G.J., and Hundal H.S. Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress. Evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathways. J. Biol. Chem. 274 (1999) 36293-36299
    • (1999) J. Biol. Chem. , vol.274 , pp. 36293-36299
    • Blair, A.S.1    Hajduch, E.2    Litherland, G.J.3    Hundal, H.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.