W7FW14F apomyoglobin amyloid aggregates-mediated apoptosis is due to oxidative stress and Akt inactivation caused by Ras and Rac

Journal of Cellular Physiology

Volumn 221, Issue 2, 2009, Pages 412-423

  Sirangelo, Ivana ^a,b   Iannuzzi, Clara ^a,b   Vilasi, Silvia ^a,b   Irace, Gaetano ^a,b   Giuberti, Gaia ^a   Misso, Gabriella ^a   D'Alessandro, Annamaria ^a   Abbruzzese, Alberto ^a,b   Caraglia, Michele ^a,b  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b NATIONAL INSTITUTE OF BIOSTRUCTURES AND BIOSYSTEMS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLCYSTEINE; APOMYOGLOBIN; CASPASE 3; CASPASE 9; GGTI 298; HEAT SHOCK PROTEIN 70; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; RAC PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; TIPIFARNIB; UNCLASSIFIED DRUG; W7FWI4F APOMYOGLOBIN; AMYLOID; APOPROTEIN; BENZAMIDE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; MYOGLOBIN; QUINOLONE DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BASAL CELL; CANCER CELL CULTURE; CELL AGGREGATION; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; FIBER; FIBROBLAST; HUMAN; HUMAN CELL; MITOCHONDRION; NEUROBLASTOMA CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SURVIVAL; TIME; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; FLUORESCENCE MICROSCOPY; METABOLISM; MOUSE; PROTEIN QUATERNARY STRUCTURE;

AMYLOID; ANIMALS; APOPROTEINS; APOPTOSIS; BENZAMIDES; CELL LINE; CELL SURVIVAL; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MICE; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MODELS, BIOLOGICAL; MUTANT PROTEINS; MYOGLOBIN; OXIDATIVE STRESS; PROTEIN STRUCTURE, QUATERNARY; PROTO-ONCOGENE PROTEINS C-AKT; QUINOLONES; RAC GTP-BINDING PROTEINS; RAS PROTEINS;

EID: 70149122185     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21871     Document Type: Article

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