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Volumn 11, Issue 10, 2009, Pages 976-986

Hypoxia-induced decrease in p53 protein level and increase in c-jun DNA binding activity results in cancer cell resistance to etoposide

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; ETOPOSIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; MYC PROTEIN; PROTEIN C JUN; PROTEIN P53; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1;

EID: 70149113948     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.09632     Document Type: Article
Times cited : (41)

References (38)
  • 2
    • 55249109006 scopus 로고    scopus 로고
    • Tumour hypoxia affects the responsiveness of cancer cells to chemotherapy and promotes cancer progression
    • Cosse JP and Michiels C (2008). Tumour hypoxia affects the responsiveness of cancer cells to chemotherapy and promotes cancer progression. Anticancer Agents Med Chem 8, 790-797.
    • (2008) Anticancer Agents Med Chem , vol.8 , pp. 790-797
    • Cosse, J.P.1    Michiels, C.2
  • 3
    • 25644446823 scopus 로고    scopus 로고
    • Hypoxia-responsive transcription factors
    • Cummins EP and Taylor CT (2005). Hypoxia-responsive transcription factors. Pflugers Arch 450, 363-371.
    • (2005) Pflugers Arch , vol.450 , pp. 363-371
    • Cummins, E.P.1    Taylor, C.T.2
  • 4
    • 40949108800 scopus 로고    scopus 로고
    • Carrot and stick: HIF-α engages c-Myc in hypoxic adaptation
    • Huang LE (2008). Carrot and stick: HIF-α engages c-Myc in hypoxic adaptation. Cell Death Differ 15, 672-677.
    • (2008) Cell Death Differ , vol.15 , pp. 672-677
    • Huang, L.E.1
  • 6
    • 0032979438 scopus 로고    scopus 로고
    • Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
    • DOI 10.1038/6854
    • Behrens A, Sibilia M, and Wagner EF (1999). Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat Genet 21, 326-329. (Pubitemid 29124945)
    • (1999) Nature Genetics , vol.21 , Issue.3 , pp. 326-329
    • Behrens, A.1    Sibilia, M.2    Wagner, E.F.3
  • 7
    • 0035958870 scopus 로고    scopus 로고
    • Protective Role for c-Jun in the Cellular Response to DNA Damage
    • DOI 10.1074/jbc.M102075200
    • Potapova O, Basu S, Mercola D, and Holbrook NJ (2001). Protective role for c-Jun in the cellular response to DNA damage. J Biol Chem 276, 28546-28553. (Pubitemid 37391569)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.30 , pp. 28546-28553
    • Potapova, O.1    Basu, S.2    Mercola, D.3    Holbrook, N.J.4
  • 8
    • 36849046868 scopus 로고    scopus 로고
    • Differential effects of hypoxia on etoposide-induced apoptosis according to the cancer cell lines
    • DOI 10.1186/1476-4598-6-61
    • Cosse JP, Sermeus A, Vannuvel K, Ninane N, Raes M, and Michiels C (2007). Differential effects of hypoxia on etoposide-induced apoptosis according to the cancer cell lines. Mol Cancer 6, 61. (Pubitemid 350226877)
    • (2007) Molecular Cancer , vol.6 , pp. 61
    • Cosse, J.-P.1    Sermeus, A.2    Vannuvel, K.3    Ninane, N.4    Raes, M.5    Michiels, C.6
  • 9
    • 33747376305 scopus 로고    scopus 로고
    • Hypoxia protects HepG2 cells against etoposide-induced apoptosis VIA a HIF-1-independent pathway
    • DOI 10.1016/j.yexcr.2006.05.018, PII S0014482706002060
    • Piret JP, Cosse JP, Ninane N, Raes M, and Michiels C (2006). Hypoxia protects HepG2 cells against etoposide-induced apoptosis via a HIF-1-independent pathway. Exp Cell Res 312, 2908-2920. (Pubitemid 44246949)
    • (2006) Experimental Cell Research , vol.312 , Issue.15 , pp. 2908-2920
    • Piret, J.-P.1    Cosse, J.-P.2    Ninane, N.3    Raes, M.4    Michiels, C.5
  • 10
    • 42649106141 scopus 로고    scopus 로고
    • Hypoxia induces protection against etoposide-induced apoptosis: Molecular profiling of changes in gene expression and transcription factor activity
    • DOI 10.1186/1476-4598-7-27
    • Sermeus A, Cosse JP, Crespin M, Mainfroid V, de Longueville F, Ninane N, Raes M, Remacle J, and Michiels C (2008). Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity. Mol Cancer 7, 27. (Pubitemid 351594154)
    • (2008) Molecular Cancer , vol.7 , pp. 27
    • Sermeus, A.1    Cosse, J.-P.2    Crespin, M.3    Mainfroid, V.4    De Longueville, F.5    Ninane, N.6    Raes, M.7    Remacle, J.8    Michiels, C.9
  • 14
    • 4944255743 scopus 로고    scopus 로고
    • Post-translational modification of p53 in tumorigenesis
    • Bode AM and Dong Z (2004). Post-translational modification of p53 in tumorigenesis. Nat Rev Cancer 4, 793-805.
    • (2004) Nat Rev Cancer , vol.4 , pp. 793-805
    • Bode, A.M.1    Dong, Z.2
  • 15
    • 0346655211 scopus 로고    scopus 로고
    • BH3-only Protein Noxa Is a Mediator of Hypoxic Cell Death Induced by Hypoxia-inducible Factor 1α
    • DOI 10.1084/jem.20030613
    • Kim JY, Ahn HJ, Ryu JH, Suk K, and Park JH (2004). BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1α. J Exp Med 199, 113-124. (Pubitemid 38076483)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.1 , pp. 113-123
    • Kim, J.-Y.1    Ahn, H.-J.2    Ryu, J.-H.3    Suk, K.4    Park, J.-H.5
  • 16
    • 0027244853 scopus 로고
    • The p53-mdm-2 autoregulatory feedback loop
    • Wu X, Bayle JH, Olson D, and Levine AJ (1993). The p53-mdm-2 autoregulatory feedback loop. Genes Dev 7, 1126-1132.
    • (1993) Genes Dev , vol.7 , pp. 1126-1132
    • Wu, X.1    Bayle, J.H.2    Olson, D.3    Levine, A.J.4
  • 17
    • 0033584842 scopus 로고    scopus 로고
    • One mechanism for cell type-specific regulation of the bax promoter by the tumor suppressor p53 is dictated by the p53 response element
    • Thornborrow EC and Manfredi JJ (1999). One mechanism for cell type-specific regulation of the bax promoter by the tumor suppressor p53 is dictated by the p53 response element. J Biol Chem 274, 33747-33756.
    • (1999) J Biol Chem , vol.274 , pp. 33747-33756
    • Thornborrow, E.C.1    Manfredi, J.J.2
  • 19
    • 33751084057 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling
    • Grimberg A,ColemanCM, ShiZ, BurnsTF,MacLachlanTK,WangW, and El-Deiry WS (2006). Insulin-like growth factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling. Cancer Biol Ther 5, 1408-1414.
    • (2006) Cancer Biol Ther , vol.5 , pp. 1408-1414
    • Grimberg, A.1    Coleman, C.M.2    Shi, Z.3    Burns, T.F.4    MacLachlan, T.K.5    Wang, W.6    El-Deiry, W.S.7
  • 20
    • 0033597221 scopus 로고    scopus 로고
    • Transcriptional activation of the human glutathione peroxidase promoter by p53
    • Tan M, Li S, SwaroopM, Guan K, Oberley LW, and Sun Y (1999). Transcriptional activation of the human glutathione peroxidase promoter by p53. J BiolChem274, 12061-12066. (Pubitemid 129518469)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.17 , pp. 12061-12066
    • Tan, M.1    Li, S.2    Swaroop, M.3    Guan, K.4    Oberley, L.W.5    Sun, Y.6
  • 21
    • 33645222782 scopus 로고    scopus 로고
    • α-Tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: Implication for sensitisation of resistant cancer cells to TRAIL apoptosis
    • Tomasetti M, Andera L, Alleva R, Borghi B, Neuzil J, and Procopio A (2006). α-Tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: implication for sensitisation of resistant cancer cells to TRAIL apoptosis. FEBS Lett 580, 1925-1931.
    • (2006) FEBS Lett , vol.580 , pp. 1925-1931
    • Tomasetti, M.1    Andera, L.2    Alleva, R.3    Borghi, B.4    Neuzil, J.5    Procopio, A.6
  • 22
    • 0031946364 scopus 로고    scopus 로고
    • Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding
    • Zhan Q, Chen IT, Antinore MJ, and Fornace AJ Jr (1998). Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding. Mol Cell Biol 18, 2768-2778. (Pubitemid 28183446)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.5 , pp. 2768-2778
    • Zhan, Q.1    Chen, I.-T.2    Antinore, M.J.3    Fornace Jr., A.J.4
  • 23
    • 0027257482 scopus 로고
    • Induction and nuclear accumulation of Fos and Jun proto-oncogenes in hypoxic cardiac myocytes
    • Webster KA, Discher DJ, and Bishopric NH (1993). Induction and nuclear accumulation of fos and jun proto-oncogenes in hypoxic cardiac myocytes. J Biol Chem 268, 16852-16858. (Pubitemid 23230004)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.22 , pp. 16852-16858
    • Webster, K.A.1    Discher, D.J.2    Bishopric, N.H.3
  • 25
    • 0037462454 scopus 로고    scopus 로고
    • Liver tumor development: C-Jun antagonizes the proapoptotic activity of p53
    • DOI 10.1016/S0092-8674(03)00042-4
    • Eferl R, Ricci R, Kenner L, Zenz R, David JP, Rath M, and Wagner EF (2003). Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell 112, 181-192. (Pubitemid 36144108)
    • (2003) Cell , vol.112 , Issue.2 , pp. 181-192
    • Eferl, R.1    Ricci, R.2    Kenner, L.3    Zenz, R.4    David, J.-P.5    Rath, M.6    Wagner, E.F.7
  • 27
    • 12144287046 scopus 로고    scopus 로고
    • Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance
    • DOI 10.1128/MCB.24.7.2875-2889.2004
    • Erler JT, Cawthorne CJ, Williams KJ, Koritzinsky M, Wouters BG, Wilson C, Miller C, Demonacos C, Stratford IJ, and Dive C (2004). Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance. Mol Cell Biol 24, 2875-2889. (Pubitemid 38381277)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.7 , pp. 2875-2889
    • Erler, J.T.1    Cawthorne, C.J.2    Williams, K.J.3    Koritzinsky, M.4    Wouters, B.G.5    Wilson, C.6    Miller, C.7    Demonacos, C.8    Stratford, I.J.9    Dive, C.10
  • 28
    • 22744447648 scopus 로고    scopus 로고
    • HIF-1α and p53: The ODD couple?
    • Fels DR and Koumenis C (2005). HIF-1α and p53: the ODD couple? Trends Biochem Sci 30, 426-429.
    • (2005) Trends Biochem Sci , vol.30 , pp. 426-429
    • Fels, D.R.1    Koumenis, C.2
  • 29
    • 15744369062 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis
    • DOI 10.1074/jbc.M411858200
    • Piret JP, Minet E, Cosse JP, Ninane N, Debacq C, Raes M, and Michiels C (2005). Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis. J Biol Chem 280, 9336-9344. (Pubitemid 40409627)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.10 , pp. 9336-9344
    • Piret, J.-P.1    Minet, E.2    Cosse, J.-P.3    Ninane, N.4    Debacq, C.5    Raes, M.6    Michiels, C.7
  • 30
    • 0042845994 scopus 로고    scopus 로고
    • Apoptosis-resistance of hypoxic cells: Multiple factors involved and a role for IAP-2
    • Dong Z, Wang JZ, Yu F, and Venkatachalam MA (2003). Apoptosis-resistance of hypoxic cells: multiple factors involved and a role for IAP-2. Am J Pathol 163, 663-671. (Pubitemid 36909427)
    • (2003) American Journal of Pathology , vol.163 , Issue.2 , pp. 663-671
    • Dong, Z.1    Wang, J.Z.2    Yu, F.3    Venkatachalam, M.A.4
  • 31
    • 34047105144 scopus 로고    scopus 로고
    • Role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance
    • DOI 10.1038/sj.onc.1210008, PII 1210008
    • Kilic M, Kasperczyk H, Fulda S, and Debatin KM (2007). Role of hypoxia inducible factor-1 α in modulation of apoptosis resistance. Oncogene 26, 2027-2038. (Pubitemid 46514744)
    • (2007) Oncogene , vol.26 , Issue.14 , pp. 2027-2038
    • Kilic, M.1    Kasperczyk, H.2    Fulda, S.3    Debatin, K.-M.4
  • 32
    • 0033569422 scopus 로고    scopus 로고
    • Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
    • Eischen CM,Weber JD, Roussel MF, Sherr CJ, and Cleveland JL (1999). Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Genes Dev 13, 2658-2669.
    • (1999) Genes Dev , vol.13 , pp. 2658-2669
    • Eischen, C.M.1    Weber, J.D.2    Roussel, M.F.3    Sherr, C.J.4    Cleveland, J.L.5
  • 36
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh Y (2003). ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 3, 155-168.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 37
    • 33748767112 scopus 로고    scopus 로고
    • Casein kinase 2 inhibition decreases hypoxia-inducible factor-1 activity under hypoxia through elevated p53 protein level
    • DOI 10.1242/jcs.03069
    • Hubert A, Paris S, Piret JP, Ninane N, Raes M, and Michiels C (2006). Casein kinase 2 inhibition decreases hypoxia-inducible factor-1 activity under hypoxia through elevated p53 protein level. J Cell Sci 119, 3351-3362. (Pubitemid 44405220)
    • (2006) Journal of Cell Science , vol.119 , Issue.16 , pp. 3351-3362
    • Hubert, A.1    Paris, S.2    Piret, J.-P.3    Ninane, N.4    Raes, M.5    Michiels, C.6


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