메뉴 건너뛰기




Volumn 30, Issue 10, 2009, Pages 907-913

Suppression of Protein Phosphatase 2 Differentially Modulates VEGF- and FGF2-Induced Signaling in Ovine Fetoplacental Artery Endothelial Cells

Author keywords

Endothelial cell; Placenta; Signaling transduction

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN PHOSPHATASE 2; PHOSPHOPROTEIN PHOSPHATASE 2A; SMALL INTERFERING RNA; VASCULOTROPIN;

EID: 70149108272     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2009.07.003     Document Type: Article
Times cited : (8)

References (45)
  • 1
    • 0002068708 scopus 로고
    • Birth weight of lambs: influences and consequences
    • Elliott K., and Knight J. (Eds), Elsevier, New York
    • Alexander G. Birth weight of lambs: influences and consequences. In: Elliott K., and Knight J. (Eds). Ciba foundation symposium 27: size at birth (1974), Elsevier, New York 215-245
    • (1974) Ciba foundation symposium 27: size at birth , pp. 215-245
    • Alexander, G.1
  • 3
    • 0029315447 scopus 로고
    • Utero-placental vascular development and placental function
    • Reynolds L.P., and Redmer D.A. Utero-placental vascular development and placental function. J Anim Sci 73 (1995) 1839-1851
    • (1995) J Anim Sci , vol.73 , pp. 1839-1851
    • Reynolds, L.P.1    Redmer, D.A.2
  • 4
    • 0005519961 scopus 로고
    • Observations upon the form and relations of the maternal and fetal vessels in the placenta of the sheep
    • Barcroft J., and Barron D.H. Observations upon the form and relations of the maternal and fetal vessels in the placenta of the sheep. Anat Rec 94 (1946) 569-595
    • (1946) Anat Rec , vol.94 , pp. 569-595
    • Barcroft, J.1    Barron, D.H.2
  • 5
    • 0002739304 scopus 로고    scopus 로고
    • Circulatory changes during gestation
    • Gluckman P.D., and Heymann M.A. (Eds), Edward Arnold Publishers, London
    • Magness R.R., and Zheng J. Circulatory changes during gestation. In: Gluckman P.D., and Heymann M.A. (Eds). Scientific basis of pediatric and perinatal medicine. 2nd edition. (1996), Edward Arnold Publishers, London 762-772
    • (1996) Scientific basis of pediatric and perinatal medicine. 2nd edition. , pp. 762-772
    • Magness, R.R.1    Zheng, J.2
  • 6
    • 0026505773 scopus 로고
    • Molecular and biological properties of the vascular endothelial growth factor family of proteins
    • Ferrara N., Houck K., Jakeman L., and Leung D.W. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr Rev 13 (1992) 18-32
    • (1992) Endocr Rev , vol.13 , pp. 18-32
    • Ferrara, N.1    Houck, K.2    Jakeman, L.3    Leung, D.W.4
  • 8
    • 0034965615 scopus 로고    scopus 로고
    • Developmental expression of vascular endothelial growth factor (VEGF) receptors and VEGF binding in ovine placenta and fetal membranes
    • Bogic L.V., Brace R.A., and Cheung C.Y. Developmental expression of vascular endothelial growth factor (VEGF) receptors and VEGF binding in ovine placenta and fetal membranes. Placenta 22 (2001) 265-275
    • (2001) Placenta , vol.22 , pp. 265-275
    • Bogic, L.V.1    Brace, R.A.2    Cheung, C.Y.3
  • 9
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N., Gerber H.P., and LeCouter J. The biology of VEGF and its receptors. Nat Med 9 (2003) 669-676
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 10
    • 0033783352 scopus 로고    scopus 로고
    • Fibroblast growth factors, their receptors and signaling
    • Powers C.J., McLeskey S.W., and Wellstein A. Fibroblast growth factors, their receptors and signaling. Endocr Relat Cancer 7 (2000) 165-197
    • (2000) Endocr Relat Cancer , vol.7 , pp. 165-197
    • Powers, C.J.1    McLeskey, S.W.2    Wellstein, A.3
  • 14
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley L.C. The phosphoinositide 3-kinase pathway. Science 296 (2002) 1655-1657
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 15
    • 4244078727 scopus 로고    scopus 로고
    • VEGF receptor signal transduction
    • Matsumoto T., and Claesson-Welsh L. VEGF receptor signal transduction. Sci STKE 2001 (2001) RE21
    • (2001) Sci STKE , vol.2001
    • Matsumoto, T.1    Claesson-Welsh, L.2
  • 16
    • 19644367000 scopus 로고    scopus 로고
    • Activation and signaling of the p38 MAP kinase pathway
    • Zarubin T., and Han J. Activation and signaling of the p38 MAP kinase pathway. Cell Res 15 (2005) 11-18
    • (2005) Cell Res , vol.15 , pp. 11-18
    • Zarubin, T.1    Han, J.2
  • 17
    • 0033965158 scopus 로고    scopus 로고
    • The p38 signal transduction pathway activation and function
    • Ono K., and Han J. The p38 signal transduction pathway activation and function. Cell Signal 12 (2000) 1-13
    • (2000) Cell Signal , vol.12 , pp. 1-13
    • Ono, K.1    Han, J.2
  • 18
    • 0032964106 scopus 로고    scopus 로고
    • Activation of the mitogen-activated protein kinase cascade is necessary but not sufficient for basic fibroblast growth factor- and epidermal growth factor-stimulated expression of endothelial nitric oxide synthase in ovine fetoplacental artery endothelial cells
    • Zheng J., Bird I.M., Melsaether A.N., and Magness R.R. Activation of the mitogen-activated protein kinase cascade is necessary but not sufficient for basic fibroblast growth factor- and epidermal growth factor-stimulated expression of endothelial nitric oxide synthase in ovine fetoplacental artery endothelial cells. Endocrinology 140 (1999) 1399-1407
    • (1999) Endocrinology , vol.140 , pp. 1399-1407
    • Zheng, J.1    Bird, I.M.2    Melsaether, A.N.3    Magness, R.R.4
  • 19
    • 0031860103 scopus 로고    scopus 로고
    • The structure and mechanism of protein phosphatases: insights into catalysis and regulation
    • Barford D., Das A.K., and Egloff M.P. The structure and mechanism of protein phosphatases: insights into catalysis and regulation. Annu Rev Biophys Biomol Struct 27 (1998) 133-164
    • (1998) Annu Rev Biophys Biomol Struct , vol.27 , pp. 133-164
    • Barford, D.1    Das, A.K.2    Egloff, M.P.3
  • 20
    • 0033970533 scopus 로고    scopus 로고
    • Dual specificity phosphatases: a gene family for control of MAP kinase function
    • Camps M., Nichols A., and Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 14 (2000) 6-16
    • (2000) FASEB J , vol.14 , pp. 6-16
    • Camps, M.1    Nichols, A.2    Arkinstall, S.3
  • 21
    • 0024792262 scopus 로고
    • Protein phosphatases come of age
    • Cohen P., and Cohen P.T. Protein phosphatases come of age. J Biol Chem 264 (1989) 21435-21438
    • (1989) J Biol Chem , vol.264 , pp. 21435-21438
    • Cohen, P.1    Cohen, P.T.2
  • 22
    • 0035754324 scopus 로고    scopus 로고
    • Protein phosphatase 2A: variety of forms and diversity of functions
    • Lechward K., Awotunde O.S., Swiatek W., and Muszynska G. Protein phosphatase 2A: variety of forms and diversity of functions. Acta Biochim Pol 48 (2001) 921-933
    • (2001) Acta Biochim Pol , vol.48 , pp. 921-933
    • Lechward, K.1    Awotunde, O.S.2    Swiatek, W.3    Muszynska, G.4
  • 23
    • 0027143725 scopus 로고
    • Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth
    • Mumby M.C., and Walter G. Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. Physiol Rev 73 (1993) 673-699
    • (1993) Physiol Rev , vol.73 , pp. 673-699
    • Mumby, M.C.1    Walter, G.2
  • 24
    • 0035100658 scopus 로고    scopus 로고
    • Protein phosphatase 2A: the Trojan Horse of cellular signaling
    • Sontag E. Protein phosphatase 2A: the Trojan Horse of cellular signaling. Cell Signal 13 (2001) 7-16
    • (2001) Cell Signal , vol.13 , pp. 7-16
    • Sontag, E.1
  • 25
    • 0032514680 scopus 로고    scopus 로고
    • Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha
    • Gotz J., Probst A., Ehler E., Hemmings B., and Kues W. Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha. Proc Natl Acad Sci U S A 95 (1998) 12370-12375
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 12370-12375
    • Gotz, J.1    Probst, A.2    Ehler, E.3    Hemmings, B.4    Kues, W.5
  • 26
    • 0029257329 scopus 로고
    • Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines
    • Alessi D.R., Gomez N., Moorhead G., Lewis T., Keyse S.M., and Cohen P. Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines. Curr Biol 5 (1995) 283-295
    • (1995) Curr Biol , vol.5 , pp. 283-295
    • Alessi, D.R.1    Gomez, N.2    Moorhead, G.3    Lewis, T.4    Keyse, S.M.5    Cohen, P.6
  • 27
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
    • Janssens V., and Goris J. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem J 353 (2001) 417-439
    • (2001) Biochem J , vol.353 , pp. 417-439
    • Janssens, V.1    Goris, J.2
  • 28
    • 0037007096 scopus 로고    scopus 로고
    • Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits
    • Silverstein A.M., Barrow C.A., Davis A.J., and Mumby M.C. Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits. Proc Natl Acad Sci U S A 99 (2002) 4221-4226
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4221-4226
    • Silverstein, A.M.1    Barrow, C.A.2    Davis, A.J.3    Mumby, M.C.4
  • 29
    • 27744512550 scopus 로고    scopus 로고
    • Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt
    • Van Kanegan M.J., Adams D.G., Wadzinski B.E., and Strack S. Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt. J Biol Chem 280 (2005) 36029-36036
    • (2005) J Biol Chem , vol.280 , pp. 36029-36036
    • Van Kanegan, M.J.1    Adams, D.G.2    Wadzinski, B.E.3    Strack, S.4
  • 30
    • 4344686261 scopus 로고    scopus 로고
    • A new role of protein phosphatase 2a in adenoviral E1A protein-mediated sensitization to anticancer drug-induced apoptosis in human breast cancer cells
    • Liao Y., and Hung M.C. A new role of protein phosphatase 2a in adenoviral E1A protein-mediated sensitization to anticancer drug-induced apoptosis in human breast cancer cells. Cancer Res 64 (2004) 5938-5942
    • (2004) Cancer Res , vol.64 , pp. 5938-5942
    • Liao, Y.1    Hung, M.C.2
  • 31
    • 0037362372 scopus 로고    scopus 로고
    • Role of PP2A in the regulation of p38 MAPK activation in bovine aortic endothelial cells exposed to cyclic strain
    • Lee T., Kim S.J., and Sumpio B.E. Role of PP2A in the regulation of p38 MAPK activation in bovine aortic endothelial cells exposed to cyclic strain. J Cell Physiol 194 (2003) 349-355
    • (2003) J Cell Physiol , vol.194 , pp. 349-355
    • Lee, T.1    Kim, S.J.2    Sumpio, B.E.3
  • 32
    • 0032857305 scopus 로고    scopus 로고
    • Protein phosphatases 1 and 2A maintain endothelial cells in a resting state, limiting the motility that is needed for the morphogenic process of angiogenesis
    • Gabel S., Benefield J., Meisinger J., Petruzzelli G.J., and Young M. Protein phosphatases 1 and 2A maintain endothelial cells in a resting state, limiting the motility that is needed for the morphogenic process of angiogenesis. Otolaryngol Head Neck Surg 121 (1999) 463-468
    • (1999) Otolaryngol Head Neck Surg , vol.121 , pp. 463-468
    • Gabel, S.1    Benefield, J.2    Meisinger, J.3    Petruzzelli, G.J.4    Young, M.5
  • 33
    • 0037143091 scopus 로고    scopus 로고
    • Protein phosphatase-2A regulates endothelial cell motility and both the phosphorylation and the stability of focal adhesion complexes
    • Young M.R., Kolesiak K., and Meisinger J. Protein phosphatase-2A regulates endothelial cell motility and both the phosphorylation and the stability of focal adhesion complexes. Int J Cancer 100 (2002) 276-282
    • (2002) Int J Cancer , vol.100 , pp. 276-282
    • Young, M.R.1    Kolesiak, K.2    Meisinger, J.3
  • 34
    • 0032992597 scopus 로고    scopus 로고
    • The protein phosphatase inhibitor cantharidin alters vascular endothelial cell permeability
    • Knapp J., Boknik P., Luss I., Huke S., Linck B., Luss H., et al. The protein phosphatase inhibitor cantharidin alters vascular endothelial cell permeability. J Pharmacol Exp Ther 289 (1999) 1480-1486
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 1480-1486
    • Knapp, J.1    Boknik, P.2    Luss, I.3    Huke, S.4    Linck, B.5    Luss, H.6
  • 35
    • 0029805917 scopus 로고    scopus 로고
    • Protein phosphatase 2A in stretch-induced endothelial cell proliferation
    • Murata K., Mills I., and Sumpio B.E. Protein phosphatase 2A in stretch-induced endothelial cell proliferation. J Cell Biochem 63 (1996) 311-319
    • (1996) J Cell Biochem , vol.63 , pp. 311-319
    • Murata, K.1    Mills, I.2    Sumpio, B.E.3
  • 36
    • 33845746208 scopus 로고    scopus 로고
    • Establishment of a functional ovine fetoplacental artery endothelial cell line with a prolonged life span
    • Song Y., and Zheng J. Establishment of a functional ovine fetoplacental artery endothelial cell line with a prolonged life span. Biol Reprod 76 (2007) 29-35
    • (2007) Biol Reprod , vol.76 , pp. 29-35
    • Song, Y.1    Zheng, J.2
  • 37
    • 38149024921 scopus 로고    scopus 로고
    • Activation of multiple signaling pathways is critical for fibroblast growth factor 2- and vascular endothelial growth factor-stimulated ovine fetoplacental endothelial cell proliferation
    • Zheng J., Wen Y., Song Y., Wang K., Chen D.B., and Magness R.R. Activation of multiple signaling pathways is critical for fibroblast growth factor 2- and vascular endothelial growth factor-stimulated ovine fetoplacental endothelial cell proliferation. Biol Reprod 78 (2008) 143-150
    • (2008) Biol Reprod , vol.78 , pp. 143-150
    • Zheng, J.1    Wen, Y.2    Song, Y.3    Wang, K.4    Chen, D.B.5    Magness, R.R.6
  • 38
    • 69449089083 scopus 로고    scopus 로고
    • Compartmentalizing VEGF-induced ERK2/1 signaling in placental artery endothelial cell caveolae: a paradoxical role of caveolin-1 in placental angiogenesis in vitro
    • [Epub ahead of print]
    • Liao W.X., Feng L., Zhang H.H., Zheng J., Moore T.R., and Chen D.B. Compartmentalizing VEGF-induced ERK2/1 signaling in placental artery endothelial cell caveolae: a paradoxical role of caveolin-1 in placental angiogenesis in vitro. Mol Endocrinol (2009; May 28) [Epub ahead of print]
    • (2009) Mol Endocrinol
    • Liao, W.X.1    Feng, L.2    Zhang, H.H.3    Zheng, J.4    Moore, T.R.5    Chen, D.B.6
  • 39
    • 53349176915 scopus 로고    scopus 로고
    • Protein phosphatase 3 differentially modulates vascular endothelial growth factor- and fibroblast growth factor 2-stimulated cell proliferation and signaling in ovine fetoplacental artery endothelial cells
    • Wang K., Song Y., Chen D.B., and Zheng J. Protein phosphatase 3 differentially modulates vascular endothelial growth factor- and fibroblast growth factor 2-stimulated cell proliferation and signaling in ovine fetoplacental artery endothelial cells. Biol Reprod 79 (2008) 704-710
    • (2008) Biol Reprod , vol.79 , pp. 704-710
    • Wang, K.1    Song, Y.2    Chen, D.B.3    Zheng, J.4
  • 40
    • 19444372406 scopus 로고    scopus 로고
    • Angiotensin II regulation of ovine fetoplacental artery endothelial functions: interactions with nitric oxide
    • Zheng J., Bird I.M., Chen D.B., and Magness R.R. Angiotensin II regulation of ovine fetoplacental artery endothelial functions: interactions with nitric oxide. J Physiol 565 (2005) 59-69
    • (2005) J Physiol , vol.565 , pp. 59-69
    • Zheng, J.1    Bird, I.M.2    Chen, D.B.3    Magness, R.R.4
  • 41
    • 33751562062 scopus 로고    scopus 로고
    • Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling
    • Rafiee P., Heidemann J., Ogawa H., Johnson N.A., Fisher P.J., Li M.S., et al. Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling. Cell Commun Signal 2 (2004) 3
    • (2004) Cell Commun Signal , vol.2 , pp. 3
    • Rafiee, P.1    Heidemann, J.2    Ogawa, H.3    Johnson, N.A.4    Fisher, P.J.5    Li, M.S.6
  • 42
    • 0029834655 scopus 로고    scopus 로고
    • The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm
    • McCright B., Rivers A.M., Audlin S., and Virshup D.M. The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm. J Biol Chem 271 (1996) 22081-22089
    • (1996) J Biol Chem , vol.271 , pp. 22081-22089
    • McCright, B.1    Rivers, A.M.2    Audlin, S.3    Virshup, D.M.4
  • 43
    • 0033625680 scopus 로고    scopus 로고
    • The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR
    • Xu Z., and Williams B.R. The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR. Mol Cell Biol 20 (2000) 5285-5299
    • (2000) Mol Cell Biol , vol.20 , pp. 5285-5299
    • Xu, Z.1    Williams, B.R.2
  • 44
    • 49049101857 scopus 로고    scopus 로고
    • Differential activation of multiple signalling pathways dictates eNOS upregulation by FGF2 but not VEGF in placental artery endothelial cells
    • Mata-Greenwood E., Liao W.X., Zheng J., and Chen D.B. Differential activation of multiple signalling pathways dictates eNOS upregulation by FGF2 but not VEGF in placental artery endothelial cells. Placenta 29 (2008) 708-717
    • (2008) Placenta , vol.29 , pp. 708-717
    • Mata-Greenwood, E.1    Liao, W.X.2    Zheng, J.3    Chen, D.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.