-
1
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
DOI 10.1016/S0092-8674(00)80901-0
-
Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE (1998) LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92:83-92. (Pubitemid 28053300)
-
(1998)
Cell
, vol.92
, Issue.1
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
2
-
-
0034687873
-
LAT, the linker for activation of T cells: A bridge between T cell-specific and general signaling pathways
-
Wange RL (2000) LAT, the linker for activation of T cells: A bridge between T cell-specific and general signaling pathways. Sci STKE 2000:RE1.
-
(2000)
Sci STKE
, vol.2000
-
-
Wange, R.L.1
-
3
-
-
3543071011
-
Transmembrane adaptor proteins: Organizers of immunoreceptor signalling
-
Horejsi V, Zhang W, Schraven B (2004) Transmembrane adaptor proteins: Organizers of immunoreceptor signalling. Nat Rev Immunol 4:603-616. (Pubitemid 39025046)
-
(2004)
Nature Reviews Immunology
, vol.4
, Issue.8
, pp. 603-616
-
-
Horejsi, V.1
Zhang, W.2
Schraven, B.3
-
4
-
-
0033103833
-
Essential role of LAT in T cell development
-
Zhang W, et al. (1999) Essential role of LAT in T cell development. Immunity 10:323-332. (Pubitemid 29165287)
-
(1999)
Immunity
, vol.10
, Issue.3
, pp. 323-332
-
-
Zhang, W.1
Sommers, C.L.2
Burshtyn, D.N.3
Stebbins, C.C.4
Dejarnette, J.B.5
Trible, R.P.6
Grinberg, A.7
Tsay, H.C.8
Jacobs, H.M.9
Kessler, C.M.10
Long, E.O.11
Love, P.E.12
Samelson, L.E.13
-
5
-
-
0032212728
-
LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway
-
Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A (1998) LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity 9:617-626. (Pubitemid 28557590)
-
(1998)
Immunity
, vol.9
, Issue.5
, pp. 617-626
-
-
Finco, T.S.1
Kadlecek, T.2
Zhang, W.3
Samelson, L.E.4
Weiss, A.5
-
6
-
-
0035898379
-
Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development
-
Sommers CL, et al. (2001) Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development. J Exp Med 194:135-142.
-
(2001)
J Exp Med
, vol.194
, pp. 135-142
-
-
Sommers, C.L.1
-
7
-
-
0345743609
-
LAT: A T lymphocyte adapter protein that couples the antigen receptor to downstream signaling pathways
-
Sommers CL, Samelson LE, Love PE (2004) LAT: A T lymphocyte adapter protein that couples the antigen receptor to downstream signaling pathways. Bioessays 26:61-67.
-
(2004)
Bioessays
, vol.26
, pp. 61-67
-
-
Sommers, C.L.1
Samelson, L.E.2
Love, P.E.3
-
8
-
-
0037076975
-
A LAT mutation that inhibits T-cell development yet induces lymphoproliferation
-
Sommers CL, et al. (2002) A LAT mutation that inhibits T-cell development yet induces lymphoproliferation. Science 296:2040-2043.
-
(2002)
Science
, vol.296
, pp. 2040-2043
-
-
Sommers, C.L.1
-
9
-
-
0037077094
-
Induction of T helper type 2 immunity by a point mutation in the LAT adaptor
-
DOI 10.1126/science.1069057
-
Aguado E, et al. (2002) Induction of T helper type 2 immunity by a point mutation in the LAT adaptor. Science 296:2036-2040. (Pubitemid 34627528)
-
(2002)
Science
, vol.296
, Issue.5575
, pp. 2036-2040
-
-
Aguado, E.1
Richelme, S.2
Nunez-Cruz, S.3
Miazek, A.4
Mura, A.-M.5
Richelme, M.6
Guo, X.-J.7
Sainty, D.8
He, H.-T.9
Malissen, B.10
Malissen, M.11
-
10
-
-
33746872949
-
Y136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity
-
Genton C, et al. (2006) The Th2 lymphoproliferation developing in LatY136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity. J Immunol 177:2285-2293. (Pubitemid 44200988)
-
(2006)
Journal of Immunology
, vol.177
, Issue.4
, pp. 2285-2293
-
-
Genton, C.1
Wang, Y.2
Izui, S.3
Malissen, B.4
Delsol, G.5
Fournie, G.J.6
Malissen, M.7
Acha-Orbea, H.8
-
11
-
-
31344480633
-
LAT-mediated signaling in CD4+CD25+ regulatory T cell development
-
Koonpaew S, Shen S, Flowers L, Zhang W (2006) LAT-mediated signaling in CD4+CD25+ regulatory T cell development. J Exp Med 203:119-129.
-
(2006)
J Exp Med
, vol.203
, pp. 119-129
-
-
Koonpaew, S.1
Shen, S.2
Flowers, L.3
Zhang, W.4
-
12
-
-
40749113582
-
Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells
-
Wang Y, et al. (2008) Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells. J Immunol 180:1565-1575.
-
(2008)
J Immunol
, vol.180
, pp. 1565-1575
-
-
Wang, Y.1
-
13
-
-
34248563290
-
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- To S-phase transition
-
DOI 10.1038/sj.onc.1210414, PII 1210414
-
Meloche S, Pouyssegur J (2007) The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-transition. Oncogene 26:3227-3239. (Pubitemid 46763017)
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3227-3239
-
-
Meloche, S.1
Pouyssegur, J.2
-
14
-
-
0037306522
-
The Ras/MAPK cascade and the control of positive selection
-
DOI 10.1034/j.1600-065X.2003.00012.x
-
Alberola-Ila J, Hernandez-Hoyos G (2003) The Ras/MAPK cascade and the control of positive selection. Immunol Rev 191:79-96. (Pubitemid 36398850)
-
(2003)
Immunological Reviews
, vol.191
, pp. 79-96
-
-
Alberola-Ila, J.1
Hernandez-Hoyos, G.2
-
15
-
-
0034658333
-
RasGRP links T-cell receptor signaling to Ras
-
Ebinu JO, et al. (2000) RasGRP links T-cell receptor signaling to Ras. Blood 95:3199-3203.
-
(2000)
Blood
, vol.95
, pp. 3199-3203
-
-
Ebinu, J.O.1
-
16
-
-
0034303371
-
RasGRP is essential for mouse thymocyte differentiation and TCR signaling
-
Dower NA, et al. (2000) RasGRP is essential for mouse thymocyte differentiation and TCR signaling. Nat Immunol 1:317-321.
-
(2000)
Nat Immunol
, vol.1
, pp. 317-321
-
-
Dower, N.A.1
-
17
-
-
38149085101
-
Regulatory mechanisms of mitogen-activated kinase signaling
-
DOI 10.1007/s00018-007-7012-3
-
Zhang YL, Dong C (2007) Regulatory mechanisms of mitogen-activated kinase signaling. Cell Mol Life Sci 64:2771-2789. (Pubitemid 351152255)
-
(2007)
Cellular and Molecular Life Sciences
, vol.64
, Issue.21
, pp. 2771-2789
-
-
Zhang, Y.1
Dong, C.2
-
18
-
-
33644976705
-
MAP kinases inimmune responses
-
Zhang YL, Dong C (2005) MAP kinases inimmune responses. Cell Mol Immunol 2:20-27.
-
(2005)
Cell Mol Immunol
, vol.2
, pp. 20-27
-
-
Zhang, Y.L.1
Dong, C.2
-
19
-
-
0028227284
-
SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: The guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases
-
Reif K, Buday L, Downward J, Cantrell DA (1994) SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: The guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T-cell antigen receptor-activated tyrosine kinases. J Biol Chem 269:14081-14087. (Pubitemid 24191162)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.19
, pp. 14081-14087
-
-
Reif, K.1
Buday, L.2
Downward, J.3
Cantrell, D.A.4
-
20
-
-
34147203741
-
Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes
-
DOI 10.1128/MCB.01882-06
-
Roose JP, Mollenauer M, Ho M, Kurosaki T, Weiss A (2007) Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes. Mol Cell Biol 27:2732-2745. (Pubitemid 46581361)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.7
, pp. 2732-2745
-
-
Roose, J.P.1
Mollenauer, M.2
Ho, M.3
Kurosaki, T.4
Weiss, A.5
-
21
-
-
58249092059
-
Digital signaling and hysteresis characterize ras activation in lymphoid cells
-
Das J, et al. (2009) Digital signaling and hysteresis characterize ras activation in lymphoid cells. Cell 136:337-351.
-
(2009)
Cell
, vol.136
, pp. 337-351
-
-
Das, J.1
-
22
-
-
58249087468
-
Origin of the sharp boundary that discriminates positive and negative selection of thymocytes
-
Prasad A, et al. (2009) Origin of the sharp boundary that discriminates positive and negative selection of thymocytes. Proc Natl Acad Sci USA 106:528-533.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 528-533
-
-
Prasad, A.1
-
23
-
-
0142250486
-
Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival
-
DOI 10.1016/S1074-7613(03)00275-9
-
Han A, Saijo K, Mecklenbrauker I, Tarakhovsky A, Nussenzweig MC (2003) Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival. Immunity 19:621-632. (Pubitemid 37311442)
-
(2003)
Immunity
, vol.19
, Issue.4
, pp. 621-632
-
-
Han, A.1
Saijo, K.2
Mecklenbrauker, I.3
Tarakhovsky, A.4
Nussenzweig, M.C.5
-
24
-
-
11144274446
-
Role of the adaptor proteins Bam32, TAPP1 and TAPP2 in lymphocyte activation
-
DOI 10.1016/j.imlet.2004.09.019, PII S016524780400272X
-
Allam A, Marshall AJ (2005) Role of the adaptor proteins Bam32, TAPP1 and TAPP2 in lymphocyte activation. Immunol Lett 97:7-17. (Pubitemid 40038850)
-
(2005)
Immunology Letters
, vol.97
, Issue.1
, pp. 7-17
-
-
Allam, A.1
Marshall, A.J.2
-
25
-
-
45749110212
-
Bam32: A novel mediator of Erk activation in T cells
-
Sommers CL, et al. (2008) Bam32: A novel mediator of Erk activation in T cells. Int Immunol 20:811-818.
-
(2008)
Int Immunol
, vol.20
, pp. 811-818
-
-
Sommers, C.L.1
-
28
-
-
0028179931
-
Involvement of p21ras activation in T cell CD69 expression
-
D'Ambrosio D, Cantrell DA, Frati L, Santoni A, Testi R (1994) Involvement of p21ras activation in T cell CD69 expression. Eur J Immunol 24:616-620. (Pubitemid 2043221)
-
(1994)
European Journal of Immunology
, vol.24
, Issue.3
, pp. 616-620
-
-
D'Ambrosio, D.1
Cantrell, D.A.2
Frati, L.3
Santoni, A.4
Testi, R.5
-
29
-
-
0031448222
-
The influence of the MAPK pathway on T cell lineage commitment
-
Sharp LL, Schwarz DA, Bott CM, Marshall CJ, Hedrick SM (1997) The influence of the MAPK pathway on T cell lineage commitment. Immunity 7:609-619.
-
(1997)
Immunity
, vol.7
, pp. 609-619
-
-
Sharp, L.L.1
Schwarz, D.A.2
Bott, C.M.3
Marshall, C.J.4
Hedrick, S.M.5
-
30
-
-
0034651940
-
The balance of protein kinase C and calcium signaling directs T cell subset development
-
Noble A, et al. (2000) The balance of protein kinase C and calcium signaling directs T cell subset development. J Immunol 164:1807-1813. (Pubitemid 30108733)
-
(2000)
Journal of Immunology
, vol.164
, Issue.4
, pp. 1807-1813
-
-
Noble, A.1
Truman, J.P.2
Vyas, B.3
Vukmanovic-Stejic, M.4
Hirst, W.J.5
Kemeny, D.M.6
-
31
-
-
33746342994
-
+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
-
+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 212:8-27.
-
(2006)
Immunol Rev
, vol.212
, pp. 8-27
-
-
Sakaguchi, S.1
-
32
-
-
40949123088
-
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T-cell activation and tolerance
-
Oh-hora M, et al. (2008) Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T-cell activation and tolerance. Nat Immunol 9:432-443.
-
(2008)
Nat Immunol
, vol.9
, pp. 432-443
-
-
Oh-hora, M.1
-
33
-
-
0032212631
-
Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development
-
Ranger AM, Oukka M, Rengarajan J, Glimcher LH (1998) Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. Immunity 9:627-635. (Pubitemid 28557591)
-
(1998)
Immunity
, vol.9
, Issue.5
, pp. 627-635
-
-
Ranger, A.M.1
Oukka, M.2
Rengarajan, J.3
Glimcher, L.H.4
-
34
-
-
4744357460
-
Overview of interleukin-2 function, production and clinical applications
-
DOI 10.1016/j.cyto.2004.06.010, PII S1043466604002200
-
Gaffen SL, Liu KD (2004) Overview of interleukin-2 function, production, and clinical applications. Cytokine 28:109-123. (Pubitemid 39313082)
-
(2004)
Cytokine
, vol.28
, Issue.3
, pp. 109-123
-
-
Gaffen, S.L.1
Liu, K.D.2
|