메뉴 건너뛰기




Volumn 4, Issue 8, 2009, Pages

The induction of APC with a distinct tolerogenic phenotype via contact-dependent STAT3 activation

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN LIKE TRANSCRIPT 3; IMMUNOGLOBULIN LIKE TRANSCRIPT 4; JANUS KINASE; JANUS KINASE INHIBITOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; STAT3 PROTEIN; UNCLASSIFIED DRUG; GAMMA INTERFERON; INTERLEUKIN 10; JAK2 PROTEIN, HUMAN; JANUS KINASE 2; TUMOR NECROSIS FACTOR ALPHA;

EID: 70049107574     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006846     Document Type: Article
Times cited : (16)

References (27)
  • 1
    • 36749003219 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells in health and disease: Friend and foe!
    • Adler HS, Steinbrink K (2007) Tolerogenic dendritic cells in health and disease: friend and foe! Eur J Dermatol 17: 476-491.
    • (2007) Eur J Dermatol , vol.17 , pp. 476-491
    • Adler, H.S.1    Steinbrink, K.2
  • 2
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity?
    • Lutz MB, Schuler G (2002) Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23: 445-449.
    • (2002) Trends Immunol , vol.23 , pp. 445-449
    • Lutz, M.B.1    Schuler, G.2
  • 3
    • 33847368558 scopus 로고    scopus 로고
    • Targeting of Jak/STAT pathway in antigen presenting cells in cancer
    • Nefedova Y, Gabrilovich DI (2007) Targeting of Jak/STAT pathway in antigen presenting cells in cancer. Curr Cancer Drug Targets 7: 71-77.
    • (2007) Curr Cancer Drug Targets , vol.7 , pp. 71-77
    • Nefedova, Y.1    Gabrilovich, D.I.2
  • 4
    • 0034693871 scopus 로고    scopus 로고
    • Janus kinases: Components of multiple signaling pathways
    • Rane SG, Reddy EP (2000) Janus kinases: components of multiple signaling pathways. Oncogene 19: 5662-5679.
    • (2000) Oncogene , vol.19 , pp. 5662-5679
    • Rane, S.G.1    Reddy, E.P.2
  • 6
    • 0141790820 scopus 로고    scopus 로고
    • A critical role for Stat3 signaling in immune tolerance
    • Cheng F, Wang HW, Cuenca A, Huang M, Ghansah T, et al. (2003) A critical role for Stat3 signaling in immune tolerance. Immunity 19: 425-436.
    • (2003) Immunity , vol.19 , pp. 425-436
    • Cheng, F.1    Wang, H.W.2    Cuenca, A.3    Huang, M.4    Ghansah, T.5
  • 7
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
    • Yu H, Kortylewski M, Pardoll D (2007) Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 7: 41-51.
    • (2007) Nat Rev Immunol , vol.7 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 8
    • 11144357779 scopus 로고    scopus 로고
    • Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
    • Wang T, Niu G, Kortylewski M, Burdelya L, Shain K, et al. (2004) Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med 10: 48-54.
    • (2004) Nat Med , vol.10 , pp. 48-54
    • Wang, T.1    Niu, G.2    Kortylewski, M.3    Burdelya, L.4    Shain, K.5
  • 9
    • 33645760428 scopus 로고    scopus 로고
    • Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype
    • Hagemann T, Wilson J, Burke F, Kulbe H, Li NF, et al. (2006) Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype. J Immunol 176: 5023-5032.
    • (2006) J Immunol , vol.176 , pp. 5023-5032
    • Hagemann, T.1    Wilson, J.2    Burke, F.3    Kulbe, H.4    Li, N.F.5
  • 10
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • Gabrilovich D (2004) Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat Rev Immunol 4: 941-952.
    • (2004) Nat Rev Immunol , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 11
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W (2005) Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer 5: 263-274.
    • (2005) Nat Rev Cancer , vol.5 , pp. 263-274
    • Zou, W.1
  • 12
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness
    • Beyth S, Borovsky Z, Mevorach D, Liebergall M, Gazit Z, et al. (2005) Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood 105: 2214-2219.
    • (2005) Blood , vol.105 , pp. 2214-2219
    • Beyth, S.1    Borovsky, Z.2    Mevorach, D.3    Liebergall, M.4    Gazit, Z.5
  • 13
    • 33847039191 scopus 로고    scopus 로고
    • Contact-dependent induction of regulatory antigen-presenting cells by human mesenchymal stem cells is mediated via STAT3 signaling
    • Gur-Wahnon D, Borovsky Z, Beyth S, Liebergall M, Rachmilewitz J (2007) Contact-dependent induction of regulatory antigen-presenting cells by human mesenchymal stem cells is mediated via STAT3 signaling. Exp Hematol 35: 426-433.
    • (2007) Exp Hematol , vol.35 , pp. 426-433
    • Gur-Wahnon, D.1    Borovsky, Z.2    Beyth, S.3    Liebergall, M.4    Rachmilewitz, J.5
  • 14
    • 25444444988 scopus 로고    scopus 로고
    • Activation of dendritic cells via inhibition of Jak2/STAT3 signaling
    • Nefedova Y, Cheng P, Gilkes D, Blaskovich M, Beg AA, et al. (2005) Activation of dendritic cells via inhibition of Jak2/STAT3 signaling. J Immunol 175: 4338-4346.
    • (2005) J Immunol , vol.175 , pp. 4338-4346
    • Nefedova, Y.1    Cheng, P.2    Gilkes, D.3    Blaskovich, M.4    Beg, A.A.5
  • 15
    • 0037444373 scopus 로고    scopus 로고
    • Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice
    • Blaskovich MA, Sun J, Cantor A, Turkson J, Jove R, et al. (2003) Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Cancer Res 63: 1270-1279.
    • (2003) Cancer Res , vol.63 , pp. 1270-1279
    • Blaskovich, M.A.1    Sun, J.2    Cantor, A.3    Turkson, J.4    Jove, R.5
  • 16
    • 43449096613 scopus 로고    scopus 로고
    • Niflumic acid renders dendritic cells tolerogenic and up-regulates inhibitory molecules ILT3 and ILT4
    • Svajger U, Vidmar A, Jeras M (2008) Niflumic acid renders dendritic cells tolerogenic and up-regulates inhibitory molecules ILT3 and ILT4. Int Immunopharmacol 8: 997-1005.
    • (2008) Int Immunopharmacol , vol.8 , pp. 997-1005
    • Svajger, U.1    Vidmar, A.2    Jeras, M.3
  • 17
    • 0036122891 scopus 로고    scopus 로고
    • Tolerization of dendritic cells by T(S) cells: The crucial role of inhibitory receptors ILT3 and ILT4
    • Chang CC, Ciubotariu R, Manavalan JS, Yuan J, Colovai AI, et al. (2002) Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat Immunol 3: 237-243.
    • (2002) Nat Immunol , vol.3 , pp. 237-243
    • Chang, C.C.1    Ciubotariu, R.2    Manavalan, J.S.3    Yuan, J.4    Colovai, A.I.5
  • 18
    • 0242285719 scopus 로고    scopus 로고
    • STAT proteins: From normal control of cellular events to tumorigenesis
    • Calo V, Migliavacca M, Bazan V, Macaluso M, Buscemi M, et al. (2003) STAT proteins: from normal control of cellular events to tumorigenesis. J Cell Physiol 197: 157-168.
    • (2003) J Cell Physiol , vol.197 , pp. 157-168
    • Calo, V.1    Migliavacca, M.2    Bazan, V.3    Macaluso, M.4    Buscemi, M.5
  • 19
    • 0035142665 scopus 로고    scopus 로고
    • Activation of STAT proteins and growth control
    • Bromberg JF (2001) Activation of STAT proteins and growth control. Bioessays 23: 161-169.
    • (2001) Bioessays , vol.23 , pp. 161-169
    • Bromberg, J.F.1
  • 20
    • 2342588122 scopus 로고    scopus 로고
    • Cell-to-cell adhesion modulates Stat3 activity in normal and breast carcinoma cells
    • Vultur A, Cao J, Arulanandam R, Turkson J, Jove R, et al. (2004) Cell-to-cell adhesion modulates Stat3 activity in normal and breast carcinoma cells. Oncogene 23: 2600-2616.
    • (2004) Oncogene , vol.23 , pp. 2600-2616
    • Vultur, A.1    Cao, J.2    Arulanandam, R.3    Turkson, J.4    Jove, R.5
  • 21
    • 0036387071 scopus 로고    scopus 로고
    • Human peripheral blood monocyte-derived interleukin-10-induced semi-mature dendritic cells induce anergic CD4(+) and CD8(+) T cells via presentation of the internalized soluble antigen and cross-presentation of the phagocytosed necrotic cellular fragments
    • Sato K, Yamashita N, Matsuyama T (2002) Human peripheral blood monocyte-derived interleukin-10-induced semi-mature dendritic cells induce anergic CD4(+) and CD8(+) T cells via presentation of the internalized soluble antigen and cross-presentation of the phagocytosed necrotic cellular fragments. Cell Immunol 215: 186-194.
    • (2002) Cell Immunol , vol.215 , pp. 186-194
    • Sato, K.1    Yamashita, N.2    Matsuyama, T.3
  • 22
    • 0012391130 scopus 로고    scopus 로고
    • Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
    • Sato K, Yamashita N, Baba M, Matsuyama T (2003) Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood 101: 3581-3589.
    • (2003) Blood , vol.101 , pp. 3581-3589
    • Sato, K.1    Yamashita, N.2    Baba, M.3    Matsuyama, T.4
  • 24
    • 59449096601 scopus 로고    scopus 로고
    • Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population
    • Zhang B, Liu R, Shi D, Liu X, Chen Y, et al. (2009) Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population. Blood 113: 46-57.
    • (2009) Blood , vol.113 , pp. 46-57
    • Zhang, B.1    Liu, R.2    Shi, D.3    Liu, X.4    Chen, Y.5
  • 25
    • 0032531094 scopus 로고    scopus 로고
    • EBI1/ CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation
    • Yanagihara S, Komura E, Nagafune J, Watarai H, Yamaguchi Y (1998) EBI1/ CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation. J Immunol 161: 3096-3102.
    • (1998) J Immunol , vol.161 , pp. 3096-3102
    • Yanagihara, S.1    Komura, E.2    Nagafune, J.3    Watarai, H.4    Yamaguchi, Y.5
  • 26
    • 0037122009 scopus 로고    scopus 로고
    • Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7
    • Verbovetski I, Bychkov H, Trahtemberg U, Shapira I, Hareuveni M, et al. (2002) Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7. J Exp Med 196: 1553-1561.
    • (2002) J Exp Med , vol.196 , pp. 1553-1561
    • Verbovetski, I.1    Bychkov, H.2    Trahtemberg, U.3    Shapira, I.4    Hareuveni, M.5
  • 27
    • 46949109577 scopus 로고    scopus 로고
    • Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness
    • Willimsky G, Czeh M, Loddenkemper C, Gellermann J, Schmidt K, et al. (2008) Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness. J Exp Med 205: 1687-1700.
    • (2008) J Exp Med , vol.205 , pp. 1687-1700
    • Willimsky, G.1    Czeh, M.2    Loddenkemper, C.3    Gellermann, J.4    Schmidt, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.