TPCK-induced apoptosis and labelling of the largest subunit of RNA polymerase II in Jurkat cells

Apoptosis

Volumn 14, Issue 10, 2009, Pages 1154-1164

  Fabian, Z ^a,b   O'Brien, P ^a   Pajecka K ^c   Fearnhead, H O ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b UNIVERSITY OF PÉCS   (Hungary)

^c SCIENCE FOUNDATION IRELAND   (Ireland)

Author keywords

Anti tosyl antibody; DFF35 45; DFF40; RNA polymerase II; RPB1; TPCK

Indexed keywords

DOXYCYCLINE; ETOPOSIDE; POLYCLONAL ANTIBODY; RNA POLYMERASE II; STAUROSPORINE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

AFFINITY LABELING; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA BINDING; ENZYME SUBUNIT; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

EID: 69949145561     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-009-0386-y     Document Type: Article

References (44)

1. QH Yang R Church-Hajduk J Ren ML Newton C Du 2003 Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis Genes Dev 17 1487 1496
2. L Vande Walle M Lamkanfi P Vandenabeele 2008 The mitochondrial serine protease HtrA2/Omi: an overview Cell Death Differ 15 453 460
3. D Chowdhury J Lieberman 2008 Death by a thousand cuts: granzyme pathways of programmed cell death Annu Rev Immunol 26 389 420
4. SC Wright QS Wei J Zhong H Zheng DH Kinder JW Larrick 1994 Purification of a 24-kD protease from apoptotic tumor cells that activates DNA fragmentation J Exp Med 180 2113 2123
5. S Bruno G Del Bino P Lassota W Giaretti Z Darzynkiewicz 1992 Inhibitors of proteases prevent endonucleolysis accompanying apoptotic death of HL-60 leukemic cells and normal thymocytes Leukemia 6 1113 1120
6. HO Fearnhead AJ Rivett D Dinsdale GM Cohen 1995 A pre-existing protease is a common effector of thymocyte apoptosis mediated by diverse stimuli FEBS Lett 357 242 246
7. FM Hughes Jr RB Evans-Storms JA Cidlowski 1998 Evidence that non-caspase proteases are required for chromatin degradation during apoptosis Cell Death Differ 5 1017 1027
8. J Murn U Urleb I Mlinaric-Rascan 2004 Internucleosomal DNA cleavage in apoptotic WEHI 231 cells is mediated by a chymotrypsin-like protease Genes Cells 9 1103 1111
9. G Schoellmann E Shaw 1962 A new method for labelling the active center of chymotrypsin Biochem Biophys Res Commun 7 36 40
10. H Zhu D Dinsdale ES Alnemri GM Cohen 1997 Apoptosis in human monocytic THP.1 cells involves several distinct targets of N-tosyl-l-phenylalanyl chloromethyl ketone (TPCK) Cell Death Differ 4 590 599
11. Y Huang MS Sheikh AJ Fornace Jr NJ Holbrook 1999 Serine protease inhibitor TPCK prevents Taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells Oncogene 18 3431 3439
12. OW Rokhlin NV Guseva AF Taghiyev RA Glover MB Cohen 2004 Multiple effects of N-alpha-tosyl-l-phenylalanyl chloromethyl ketone (TPCK) on apoptotic pathways in human prostatic carcinoma cell lines Cancer Biol Ther 3 761 768
13. K Kim KH Choi YM Fu GG Meadows CO Joe 2003 Dephosphorylation of p53 during cell death by N-alpha-tosyl-l-phenylalanyl chloromethyl ketone Biochem Biophys Res Commun 306 954 958
14. BA Ballif A Shimamura E Pae J Blenis 2001 Disruption of 3-phosphoinositide-dependent kinase 1 (PDK1) signaling by the anti-tumorigenic and anti-proliferative agent n-alpha-tosyl-l-phenylalanyl chloromethyl ketone J Biol Chem 276 12466 12475
15. JA Cromlish RG Roeder 1989 Human transcription factor IIIC (TFIIIC). Purification, polypeptide structure, and the involvement of thiol groups in specific DNA binding J Biol Chem 264 18100 18109
16. T Henkel T Machleidt I Alkalay M Kronke Y Ben-Neriah PA Baeuerle 1993 Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B Nature 365 182 185
17. TC Grammer J Blenis 1996 The serine protease inhibitors, tosylphenylalanine chloromethyl ketone and tosyllysine chloromethyl ketone, potently inhibit pp70s6 k activation J Biol Chem 271 23650 23652
18. Y Chen 1999 Selective inhibition of ras-transformed cell growth by a novel fatty acid-based chloromethyl ketone designed to target Ras endoprotease Ann N Y Acad Sci 886 103 108
19. MS Pasternack MV Sitkovsky HN Eisen 1983 The site of action of N-alpha-tosyl-l-lysyl-chloromethyl-ketone (TLCK) on cloned cytotoxic T lymphocytes J Immunol 131 2477 2483
20. Harlow E, Lane D (1988) Antibodies: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp 100-120
21. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254
22. KM Ryan KH Vousden 1998 Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest Mol Cell Biol 18 3692 3698
23. LW Fung C Ho EF Roth Jr RL Nagel 1975 The alkylation of hemoglobin S by nitrogen mustard. High resolution proton nuclear magnetic resonance studies J Biol Chem 250 4786 4789
24. CC Price GM Gaucher P Koneru R Shibakawa JR Sowa M Yamaguchi 1968 Relative reactivities for monofunctional nitrogen mustard alkylation of nucleic acid components Biochim Biophys Acta 166 327 359
25. U Bhatia K Danishefsky F Traganos Z Darzynkiewicz 1995 Induction of apoptosis and cell cycle-specific change in expression of p53 in normal lymphocytes and MOLT-4 leukemic cells by nitrogen mustard Clin Cancer Res 1 873 880
26. PM O'Connor K Wassermann M Sarang I Magrath VA Bohr KW Kohn 1991 Relationship between DNA cross-links, cell cycle, and apoptosis in Burkitt's lymphoma cell lines differing in sensitivity to nitrogen mustard Cancer Res 51 6550 6557
27. BB Wolf M Schuler F Echeverri DR Green 1999 Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation J Biol Chem 274 30651 30656
28. JY Jeong KU Kim DM Jue 1997 Tosylphenylalanine chloromethyl ketone inhibits TNF-alpha mRNA synthesis in the presence of activated NF-kappa B in RAW 264.7 macrophages Immunology 92 267 273
29. M Mbikay MD Garrick 1981 Inhibition of initiation of protein synthesis by tosyl-l-lysyl chloromethyl ketone Can J Biochem 59 321 327 (Pubitemid 11057920)
30. G Vidali J Karn VG Allfrey 1975 Selective effects of inhibitors of protein synthesis on metabolism of nuclear and cytoplasmic proteins: evidence for coordinate synthesis of non-histone chromosomal proteins Proc Natl Acad Sci USA 72 4450 4454
31. SJ Martin SV Lennon AM Bonham TG Cotter 1990 Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis J Immunol 145 1859 1867
32. FS Young FC Neidhardt 1978 Effect of inhibitors of elongation factor Tu on the metabolic regulation of protein synthesis in Escherichia coli J Bacteriol 135 675 686
33. RD Chapman M Heidemann TK Albert, et al. 2007 Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7 Science 318 1780 1782
34. BW Matthews PB Sigler R Henderson DM Blow 1967 Three-dimensional structure of tosyl-alpha-chymotrypsin Nature 214 652 656
35. S Hara HD Halicka S Bruno J Gong F Traganos Z Darzynkiewicz 1996 Effect of protease inhibitors on early events of apoptosis Exp Cell Res 223 372 384
36. J Jonak I Rychlik 1973 Study of conditions for the inhibitory effect of N-tosyl-l-phenylalanylchloromethane on protein synthesis and the possibility of existence of different forms of the elongation factor S3 in Bacillus stearothermophilus Biochim Biophys Acta 324 554 562
37. ME Peter J Brockmoller J Jonak M Sprinzl 1989 Identification of the N-tosyl-l-phenylalanyl chloromethylketone modification site in Thermus thermophilus elongation factor Tu FEBS Lett 257 219 222
38. HP Phatnani AL Greenleaf 2006 Phosphorylation and functions of the RNA polymerase II CTD Genes Dev 20 2922 2936
39. MK Kim VM Nikodem 1999 hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation Mol Cell Biol 19 6833 6844
40. L Du SL Warren 1997 A functional interaction between the carboxy-terminal domain of RNA polymerase II and pre-mRNA splicing J Cell Biol 136 5 18 (Pubitemid 27044800)
41. S [tmp] McCracken N Fong E Rosonina, et al. 1997 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II Genes Dev 11 3306 3318
42. A Meinhart P Cramer 2004 Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors Nature 430 223 226
43. N Custodio M Vivo M Antoniou M Carmo-Fonseca 2007 Splicing- and cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site J Cell Biol 179 199 207
44. SJ Jeong HJ Kim YJ Yang, et al. 2005 Role of RNA polymerase II carboxy terminal domain phosphorylation in DNA damage response J Microbiol 43 516 522