Structure-based discovery of low molecular weight compounds that stimulate neurite outgrowth and substitute for nerve growth factor

Journal of Neurochemistry

Volumn 110, Issue 6, 2009, Pages 1876-1884

  Williams, Britney ^a   Dwyer, Donard S ^a,b  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b Louisiana State University Health Sciences Center at Shreveport   (United States)

Author keywords

Neurite outgrowth; Neuroprotection; Olanzapine; Structure based discovery

Indexed keywords

2 ANILINOADENOSINE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; 4',6' DIAMIDINO 2 PHENYLINDOLE; CHLOROPHENYLTHIOADENOSINE 3',5' PHOSPHATE; GLUTAMINE; INDOLE DERIVATIVE; LSU D84; NERVE GROWTH FACTOR; NEUROPROTECTIVE AGENT; OLANZAPINE; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; NERVE FIBER GROWTH; NEUROPROTECTION; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; BENZODIAZEPINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; NERVE GROWTH FACTOR; NEURITES; NEUROPROTECTIVE AGENTS; PC12 CELLS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; SEROTONIN UPTAKE INHIBITORS; TIME FACTORS;

EID: 69949112650     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06291.x     Document Type: Article

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