Deceleration of senescence in normal human fibroblasts by withanone extracted from Ashwagandha leaves

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 64, Issue 10, 2009, Pages 1031-1038

  Widodo, Nashi ^a,b   Shah, Navjot ^a,c   Priyandoko, Didik ^a,c   Ishii, Tetsuro ^a,c   Kaul, Sunil C ^a   Wadhwa, Renu ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b BRAWIJAYA UNIVERSITY   (Indonesia)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Ashwagandha; Extract; Human fibroblasts; Oxidative damage; Proteasomal activity; Senescence

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; PLANT MEDICINAL PRODUCT; PROTEASOME; WITHAFERIN A; WITHANIA SOMNIFERA EXTRACT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DIVISION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; SENESCENCE; WITHANIA SOMNIFERA;

APOPTOSIS REGULATORY PROTEINS; BETA-GALACTOSIDASE; CELL AGING; CELL CULTURE TECHNIQUES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FIBROBLASTS; HUMANS; OXIDATIVE STRESS; PLANT EXTRACTS; PLANT LEAVES; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA-BINDING PROTEINS; WITHANIA; WITHANOLIDES;

WITHANIA SOMNIFERA;

EID: 69949094416     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/glp088     Document Type: Article

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