A kindred with familial progressive hyperpigmentation-like disorder: Implication of fibroblast-derived growth factors in pigmentation

European Journal of Dermatology

Volumn 19, Issue 5, 2009, Pages 469-473

  Cardinali, Giorgia ^a   Kovacs, Daniela ^a   Del Giglio, Micol ^b   Cota, Carlo ^a   Aspite, Nicaela ^a   Amantea, Ada ^a   Girolomoni, Giampiero ^b   Picardo, Mauro ^a  

^a SAN GALLICANO DERMATOLOGICAL INSTITUTE   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

Fibroblasts; Hyperpigmentation; Melanogenic growth factors

Indexed keywords

KERATINOCYTE GROWTH FACTOR; SCATTER FACTOR; STEM CELL FACTOR;

ADULT; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CAFE AU LAIT SPOT; CASE REPORT; CELL ACTIVATION; FAMILIAL DISEASE; FAMILIAL PROGRESSIVE HYPERPIGMENTATION; FEMALE; HUMAN; HUMAN TISSUE; HYPERPIGMENTATION; HYPOPIGMENTATION; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LENTIGO; MALE; MELANOSOME; PROTEIN EXPRESSION; SKIN BIOPSY; TRANSMISSION ELECTRON MICROSCOPY;

ADULT; FEMALE; FIBROBLAST GROWTH FACTOR 7; FIBROBLASTS; HEPATOCYTE GROWTH FACTOR; HUMANS; HYPERPIGMENTATION; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; STEM CELL FACTOR;

EID: 69849088906     PISSN: 11671122     EISSN: 19524013     Source Type: Journal    
DOI: 10.1684/ejd.2009.0724     Document Type: Article

References (41)

1. Alaluf S, Barrett K, Blount M, Carter N. Ethnic variation in tyrosinase and TYRP1 expression in photoexposed and photoprotected human skin. Pigment Cell Res 2003; 16: 35-42. (Pubitemid 36596692)
2. Thong HY, Jee SH, Sun CC, Boissy RE. The patterns of melanosome distribution in keratinocytes of human skin as one determining factor of skin colour. Br J Dermatol 2003; 149: 498-505.
3. Babiarz-Magee L, Chen N, Seiberg M, Lin C. The expression and activation of protease-activated receptor 2 correlate with skin color. Pigment Cell Res 2004; 17: 241-251 (Pubitemid 38724554)
4. Imokawa G. Autocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders. Pigment Cell Res 2004; 17: 96-110. (Pubitemid 38419636)
5. Cario-André M, Pain C, Gauthier Y, Casoli V, Taïeb A. In vivo and in vitro evidence of dermal fibroblasts influence on human epidermal pigmentation. Pigment Cell Res 2006; 19: 434-442
6. Yada Y, Higuchi K, Imokawa G. Effects of endothelins on signal transduction and proliferation in human melanocytes. J Biol Chem 1991; 266: 18352-18357 (Pubitemid 21908087)
7. Hachiya A, Kobayashi A, Ohuchi A, Takema Y, Imokawa G. The paracrine role of stem cell factor/c-kit signaling in the activation of human melanocytes in ultraviolet B-induced pigmentation. J Invest Dermatol 2001; 116: 578-586 (Pubitemid 32299848)
8. Imokawa G, Yada Y, Rimura M. Signaling mechanisms of endothelin-induced mitogenesis in human melanocytes. Biochem J 1996; 314: 305-312 (Pubitemid 126732862)
9. Imokawa G, Miyagishi M, Yada Y. Endothelin-1 as a new melanogen: coordinated expression of its gene and the tyrosinase gene in UVB-exposed human epidermis. J Invest Dermatol 1995; 105: 32-37
10. Kadono S, Manaka I, Kawashima M, Kobayashi T, Imokawa G. The role of the epidermal endothelin cascade in the hyperpigmentation mechanism of lentigo senilis. J Invest Dermatol 2001; 116: 571-577 (Pubitemid 32299847)
11. Hattori H, Kawashima M, Ichikawa Y, Imokawa G. The epidermal stem cell factor is over-expressed in lentigo senilis: implication for the mechanism of hyperpigmentation. J Invest Dermatol 2004; 122: 1256-1265 (Pubitemid 38651102)
12. Kang HY, Hwang JS, Lee JY, Ahn JH, Kim JY, Lee ES, Kang WH. The dermal stem cell factor and c-Kit are overexpressed in melasma. Br J Dermatol 2006; 154: 1094-1099 (Pubitemid 43727390)
13. Manaka I, Kadono S, Kawashima M, Kobayashi T, Imokawa G. The mechanism of hyperpigmentation in seborrhoeic keratosis involves the high expression of endothelin-converting enzyme-1 and TNF, which stimulate secretion of endothelin-1. Br J Dermatol 2001; 145: 895-903. (Pubitemid 34204463)
14. Shishido E, Kadono S, Manaka I, Kawashima M, Imokawa G. The mechanism of epidermal hyperpimenation in dermatofibroma is associated with stem cell factor and hepatocyte growth factor expression. J Invest Dermatol 2001; 117: 627-633 (Pubitemid 32955590)
15. Picardo M, Briganti S, Cardinali G, Flori E, Maresca V. Tyrosinase and inhibitors of pigmentation. Conjoint Meeting of XXth International Pigment Cell Conference (IPCC) & Vth International Melanoma Research Congress (IMRC), Royton Sapporo, Japan. Pigment Cell Melanoma Res 2008; 21: 265-266
16. Okazaki M, Yoshimura K, Suzuki Y, Uchida G, Kitano Y, Imokawa G. The mechanism of epidermal hyperpigmentation in cafè-au-lait macules of neurofibromatosis type 1 (von Recklinghausen's disease) may be associated with dermal fibroblast-derived stem cell factor and hepatocyte growth factor. Br J Dermatol 2003; 148: 689-697 (Pubitemid 36629746)
17. Chen N, Li WH, Hu Y, Zhang L, Eisinger M, Seiberg M, Lin C. The role of KGF and IL-1 in melanogenesis: a possible molecular mechanism for the initiation of hyperpigmentary lesions. Conjoint Meeting of XXth International Pigment Cell Conference (IPCC) & Vth International Melanoma Research Congress (IMRC), Royton Sapporo, Japan. Pigment Cell Melanoma Res 2008; 21: 266.
18. Kovacs D, Falchi M, Cardinali G, et al. Immunohistochemical analysis of keratinocyte growth factor and fibroblast growth factor 10 expression in psoriasis. Exp Dermatol 2005; 14: 130-137 (Pubitemid 40277580)
19. Kovacs D, Cota C, Cardinali G, et al. Expression of Keratinocyte growth factor and its receptor in Clear Cell acanthoma. Exp Dermatol 2006; 15: 762-768 (Pubitemid 44425727)
20. Palmieri C, Roberts-Clark D, Assadi-Sabet A, et al. Fibroblast growth factor 7, secreted by breast fibroblasts, is an interleukin- 1beta-induced paracrine growth factor for human breast cells. J Endocrinol 2003; 177: 65-81. (Pubitemid 36592588)
21. LaRochelle WJ, Dirsch OR, Finch PW, et al. Specific receptor detection by a functional keratinocyte growth factor-immunoglobulin chimera. J Cell Biol 1995; 129: 357-366
22. Wolf HK, Zarnegar R, Michalopoulos GK. Localization of hepatocyte growth factor in human and rat tissues: an immunohistochemical study. Hepatology 1991; 14: 488-494
23. Lu YP, Nishigai K, Ishiwata T, Asano G. Differential expression of hepatocyte growth factor and its receptor (c-Met) in a rat artificial anus model. Wound Repair Regen 2000; 8: 59-67. (Pubitemid 30140800)
24. Yamaguchi Y, Itami S, Watabe H, et al. Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation. J Cell Biol 2004; 165: 275-285 (Pubitemid 38544530)
25. Yamaguchi Y, Hearing VJ, Itami S, Yoshikawa K, Katayama I. Mesenchymal-epithelial interactions in the skin: aiming for sitespecific tissue regeneration. J Dermatol Sci 2005; 40: 1-9. (Pubitemid 41383892)
26. Miki T, Bottaro DP, Fleming TP, et al. Determination of ligandbinding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci USA 1992; 89: 246-250
27. Marchese C, Maresca V, Cardinali G, et al. UVB-induced activation and internalization of keratinocyte growth factor receptor. Oncogene 2003; 22: 2422-2431 (Pubitemid 36560726)
28. Belleudi F, Leone L, Aimati L, et al. Endocytic pathways and biological effects induced by UVB-dependent or ligand-dependent activation of the keratinocyte growth factor receptor. FASEB J 2006; 20: 395-397 (Pubitemid 46671183)
29. Cardinali G, Ceccarelli S, Kovacs D, et al. Keratinocyte growth factor promotes melanosome transfer to keratinocytes. J Invest Dermatol 2005; 125: 1190-1199
30. Cardinali G, Bolasco G, Aspite N, et al. Melanosome transfer promoted by keratinocyte growth factor in light and dark skin-derived keratinocytes. J Invest Dermatol 2008; 128: 558-567 (Pubitemid 351252665)
31. Xing QH, Wang MT, Chen XD, et al. A gene locus responsible for dyschromatosis symmetrica hereditaria (DSH) maps to chromosome 6q24.2-q25.2. Am J Hum Genet 2003; 73: 377-382
32. Suzuki N, Suzuki T, Inagaki K, Ito S, Kono M, Fukai K, et al. Mutation analysis of the ADAR1 gene in dyschromatosis symmetrica hereditaria and genetic differentiation from both dyschromatosis universalis hereditaria and acropigmentation reticularis. J Invest Dermatol 2005; 124: 1186-1192 (Pubitemid 40847405)
33. Zanardo L, Stolz W, Schmitz G, et al. Progressive hyperpigmentation and generalized lentiginosis without associated systemic symptoms: a rare hereditary pigmentation disorder in south-east Germany. Acta Derm Venereol 2004; 84: 57-60. (Pubitemid 38168365)
34. Betts CM, Bardazzi F, Fanti PA, Tosti A, Varotti C. Progressive hyperpigmentation: case report with a clinical, histological, and ultrastructural investigation. Dermatology 1994; 189: 384-391 (Pubitemid 24357992)
35. Nuber UA, Tinschert S, Mundlos S, Hauber I. Dyschromatosis universalis hereditaria: familial case and ultrastructural skin investigation. Am J Med Genet A 2004; 125: 261-266 (Pubitemid 38294844)
36. Al Hawsawi K, Al Aboud K, Ramesh V, Al Aboud D. Dyschromatosis universalis hereditaria: report of a case and review of the literature. Pediatr Dermatol 2002; 19: 523-526 (Pubitemid 35425154)
37. Sandhu K, Saraswat A, Kanwar AJ. Dowling-Degos disease with dyschcromatosis universalis hereditaria-like pigmentation in a family. J Eur Acad Dermatol Venereol 2004; 18: 702-704 (Pubitemid 39429713)
38. Wu YH, Lin YC. Generalized Dowling-Degos disease. J Am Acad Dermatol 2007; 57: 327-334
39. Aoki H, Moro O, Tagami H, Kishimoto J. Gene expression profiling analysis of solar lentigo in relation to immunohistochemical characteristics. Br J Dermatol 2007; 156: 1214-1223 (Pubitemid 47029803)
40. Unver N, Freyschmidt-Paul P, Hörster S, et al. Alterations in the epidermal-dermal melanin axis and factor XIIIa melanophages in senile lentigo and ageing skin. Br J Dermatol 2006; 155: 119-128 (Pubitemid 43876404)
41. Cario-André M, Lepreux S, Pain C, Nizard C, Noblesse E, Taïeb A. Perilesional vs. lesional skin changes in senile lentigo. J Cutan Phatol 2004; 31: 441-447 (Pubitemid 38845135)