메뉴 건너뛰기




Volumn 8, Issue 17, 2009, Pages 2789-2793

Abnormal activation of the Akt-GSK3β signaling pathway in peripheral blood T cells from patients with systemic lupus erythematosus

Author keywords

Akt; Cell cycle; GSK3 ; Systemic lupus erythematosus (SLE); T lymphocytes

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLYCOGEN SYNTHASE KINASE 3; LITHIUM CHLORIDE; PHYTOHEMAGGLUTININ; PROTEIN GSK3 BETA; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 69749102963     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.17.9446     Document Type: Article
Times cited : (30)

References (23)
  • 1
    • 0029994333 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Kotzin BL. Systemic lupus erythematosus. Cell 1996; 85:303-306
    • (1996) Cell , vol.85 , pp. 303-306
    • Kotzin, B.L.1
  • 2
    • 0033178269 scopus 로고    scopus 로고
    • Anti-DNA autoantibodies: A puzzle of autoimmune phenomena
    • DOI 10.1016/S0167-5699(99)01457-7, PII S0167569999014577
    • Eilat D, Naparstek Y. Anti-DNA autoantibodies: a puzzle of autoimmune phenomena. Immunol Today 1999; 20:339-342 (Pubitemid 29356425)
    • (1999) Immunology Today , vol.20 , Issue.8 , pp. 339-342
    • Eilat, D.1    Naparstek, Y.2
  • 3
    • 0031727164 scopus 로고    scopus 로고
    • Reciprocal T-B determinant spreading develops spontaneously in murine lupus: Implications for pathogenesis
    • Singh RR, Hahn BH. Reciprocal T-B determinant spreading develops spontaneously in murine lupus: implications for pathogenesis. Immunol Rev 1998; 164:201-208
    • (1998) Immunol Rev , vol.164 , pp. 201-208
    • Singh, R.R.1    Hahn, B.H.2
  • 4
    • 0035043299 scopus 로고    scopus 로고
    • Treatment of lupus with corticosteroids
    • Chatham WW, Kimberly RP. Treatment of lupus with corticosteroids. Lupus 2001; 10:140-147
    • (2001) Lupus , vol.10 , pp. 140-147
    • Chatham, W.W.1    Kimberly, R.P.2
  • 6
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ. Cancer cell cycles. Science 1996; 274:1671-1676
    • (1996) Science , vol.274 , pp. 1671-1676
    • Sherr, C.J.1
  • 7
    • 3342890491 scopus 로고    scopus 로고
    • Lupus-like autoimmunity caused by defects in T-cell signal transduction
    • King PD. Lupus-like autoimmunity caused by defects in T-cell signal transduction. Curr Opin Investig Drugs 2004; 5:517-523
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 517-523
    • King, P.D.1
  • 8
    • 0037388451 scopus 로고    scopus 로고
    • Pathogenic T cells in murine lupus exhibit spontaneous signaling activity through phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways
    • DOI 10.1002/art.10900
    • Niculescu F, Nguyen P, Niculescu T, Rus H, Rus V, Via CS. Pathogenic T cells in murine lupus exhibit spontaneous signaling activity through phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways. Arthritis Rheum 2003; 48:1071-1079 (Pubitemid 36418250)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.4 , pp. 1071-1079
    • Niculescu, F.1    Nguyen, P.2    Niculescu, T.3    Rus, H.4    Rus, V.5    Via, C.S.6
  • 10
    • 19544376461 scopus 로고    scopus 로고
    • Review of classification criteria for systemic lupus erythematosus
    • DOI 10.1016/j.rdc.2005.01.009, PII S0889857X05000116, Sytemic Lupus Erythematosus
    • Petri M. Review of classification criteria for systemic lupus erythematosus. Rheum Dis Clin North Am 2005; 31:245-254 (Pubitemid 40732487)
    • (2005) Rheumatic Disease Clinics of North America , vol.31 , Issue.2 , pp. 245-254
    • Petri, M.1
  • 12
    • 0030970643 scopus 로고    scopus 로고
    • Control of cell cycle progression in human natural killer cells through redox regulation of expression and phosphorylation of retinoblastoma gene product protein
    • Yamauchi A, Bloom ET. Control of cell cycle progression in human natural killer cells through redox regulation of expression and phosphorylation of retinoblastoma gene product protein. Blood 1997; 89:4092-4099 (Pubitemid 27220956)
    • (1997) Blood , vol.89 , Issue.11 , pp. 4092-4099
    • Yamauchi, A.1    Bloom, E.T.2
  • 14
    • 0033662144 scopus 로고    scopus 로고
    • Cell cycle regulation in immunity, tolerance and autoimmunity
    • Balomenos D, Martinez-A C. Cell cycle regulation in immunity, tolerance and autoimmunity. Immunol Today 2000; 21:551-555
    • (2000) Immunol Today , vol.21 , pp. 551-555
    • Balomenos, D.1    Martinez-A, C.2
  • 16
    • 0034658320 scopus 로고    scopus 로고
    • Protein kinase B regulates T lymphocyte survival, nuclear factor B activation, and Bcl-X(L) levels in vivo
    • Jones RG, Parsons M, Bonnard M, Chan VS, Yeh WC, Woodgett JR, Ohashi PS. Protein kinase B regulates T lymphocyte survival, nuclear factor B activation, and Bcl-X(L) levels in vivo. J Exp Med 2000; 191:1721-1734
    • (2000) J Exp Med , vol.191 , pp. 1721-1734
    • Jones, R.G.1    Parsons, M.2    Bonnard, M.3    Chan, V.S.4    Yeh, W.C.5    Woodgett, J.R.6    Ohashi, P.S.7
  • 19
    • 4744375264 scopus 로고    scopus 로고
    • GSK-3beta inhibition by lithium confers resistance to chemotherapy-induced apoptosis through the repression of CD95 (Fas/APO-1) expression
    • DOI 10.1016/j.yexcr.2004.08.001, PII S0014482704004409
    • Beurel E, Kornprobst M, Blivet-Van Eggelpoel MJ, Ruiz-Ruiz C, Cadoret A, Capeau J, Desbois-Mouthon C. GSK-3beta inhibition by lithium confers resistance to chemotherapy- induced apoptosis through the repression of CD95 (Fas/APO-1) expression. Exp Cell Res 2004; 300:354-364 (Pubitemid 39314425)
    • (2004) Experimental Cell Research , vol.300 , Issue.2 , pp. 354-364
    • Beurel, E.1    Kornprobst, M.2    Blivet-Van Eggelpoel, M.-J.3    Ruiz-Ruiz, C.4    Cadoret, A.5    Capeau, J.6    Desbois-Mouthon, C.7
  • 20
    • 10944237268 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase
    • DOI 10.1074/jbc.M408607200
    • Liu S, Yu S, Hasegawa Y, Lapushin R, Xu HJ, Woodgett JR, et al. Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase. J Biol Chem 2004; 279:51075-51081 (Pubitemid 40017849)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.49 , pp. 51075-51081
    • Liu, S.1    Yu, S.2    Hasegawa, Y.3    Lapushin, R.4    Xu, H.-J.5    Woodgett, J.R.6    Mills, G.B.7    Fang, X.8
  • 21
    • 34247623111 scopus 로고    scopus 로고
    • Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3b/NAG-1 pathway
    • DOI 10.1016/j.canlet.2006.11.032, PII S0304383506006604
    • Pang RP, Zhou JG, Zeng ZR, Li XY, Chen W, Chen MH, Hu PJ. Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3b/NAG-1 pathway. Cancer Letters 2007; 251:268-277 (Pubitemid 46671612)
    • (2007) Cancer Letters , vol.251 , Issue.2 , pp. 268-277
    • Pang, R.-P.1    Zhou, J.-G.2    Zeng, Z.-R.3    Li, X.-Y.4    Chen, W.5    Chen, M.-H.6    Hu, P.-J.7
  • 22
    • 17544374351 scopus 로고    scopus 로고
    • T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3
    • DOI 10.1074/jbc.271.19.11410
    • Welsh GI, Miyamoto S, Price NT, Safer B, Proud CG. T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3. J Biol Chem 1996; 271:11410-11413 (Pubitemid 26155980)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.19 , pp. 11410-11413
    • Welsh, G.I.1    Miyamoto, S.2    Priced, N.T.3    Safer, B.4    Proud, C.G.5
  • 23
    • 34248152731 scopus 로고    scopus 로고
    • Unrestrained glycogen synthase kinase-3beta activity leads to activated T cell death and can be inhibited by natural adjuvant
    • Sengupta S, Jayaraman P, Chilton PM, Casella CR, Mitchell TC. Unrestrained Glycogen Synthase Kinase-3beta Activity Leads to Activated T Cell Death and Can Be Inhibited by Natural Adjuvant. J Immunol 2007; 178:6083-6091 (Pubitemid 46717388)
    • (2007) Journal of Immunology , vol.178 , Issue.10 , pp. 6083-6091
    • Sengupta, S.1    Jayaraman, P.2    Chilton, P.M.3    Casella, C.R.4    Mitchell, T.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.