Abnormal Shh and FOXC2 expression correlates with aberrant lymphatic development in human fetuses with increased nuchal translucency

Prenatal Diagnosis

Volumn 29, Issue 9, 2009, Pages 840-846

  De Mooij, Yolanda M ^a,b   Van Den Akker, Nynke M S ^a,c   Bekker, Mireille N ^b   Bartelings, Margot M ^a   Wisse, Lambertus J ^a   Van Vugt, John M G ^b   Gittenberger de Groot, Adriana C ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

FOXC2; Jugular lymphatic sac; Lymphatic development; Nuchal translucency; Shh

Indexed keywords

PLATELET DERIVED GROWTH FACTOR B; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR FOXC2; VASCULOTROPIN A;

ARTICLE; BLOOD VESSEL WALL; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FETUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHANGIOGENESIS; LYMPHOCYTE; NUCHAL TRANSLUCENCY MEASUREMENT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; TRISOMY 21; UPREGULATION;

BIOLOGICAL MARKERS; BLOOD VESSELS; DOWN SYNDROME; ENDOTHELIAL CELLS; FEMALE; FETAL DEVELOPMENT; FETAL HEART; FETUS; FORKHEAD TRANSCRIPTION FACTORS; HEDGEHOG PROTEINS; HUMANS; LYMPHATIC SYSTEM; LYMPHATIC VESSELS; NECK; NUCHAL TRANSLUCENCY MEASUREMENT; PREGNANCY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ERINACEIDAE;

EID: 69749098035     PISSN: 01973851     EISSN: 10970223     Source Type: Journal    
DOI: 10.1002/pd.2316     Document Type: Article

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