Voltage-gated sodium channels in nociception and their potential as targets for new drugs in treatment of chronic neuropathic pain

Current Anaesthesia and Critical Care

Volumn 20, Issue 5-6, 2009, Pages 204-208

  Lees, George ^a   Shipton, Edward ^b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Analgesic; Inflammatory pain; Ion channels; Neuropathic pain; Voltage gated sodium channel (VGSC)

Indexed keywords

AMITRIPTYLINE; ANALGESIC AGENT; ANTICONVULSIVE AGENT; CARBAMAZEPINE; CONOTOXIN; GABAPENTIN; HARKOSERIDE; LAMOTRIGINE; MESSENGER RNA; MU CONOTOXIN; NARCOTIC ANALGESIC AGENT; OMEGA CONOTOXIN MVIIA; SODIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.3; SODIUM CHANNEL NAV1.4; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL NAV1.6; SODIUM CHANNEL NAV1.7; SODIUM CHANNEL NAV1.8; SODIUM CHANNEL NAV1.9; TRAMADOL; UNCLASSIFIED DRUG; VALPROIC ACID; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; CHRONIC PAIN; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; DRUG SELECTIVITY; DRUG TARGETING; DYSESTHESIA; GENE EXPRESSION; GENE MUTATION; HUMAN; HYPOTENSION; NERVE CONDUCTION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

EID: 69649093196     PISSN: 09537112     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cacc.2009.06.002     Document Type: Article

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