메뉴 건너뛰기




Volumn 17, Issue 1, 2009, Pages 62-69

Suppressive actions of Astragali Radix (AR) ethanol extract and isolated astragaloside I on HCL/ethanol-induced gastric lesions

Author keywords

Astragali Radix (AR); Astragaloside I; Astragalus membranaceus; Gastritis; Helicobacter pylori

Indexed keywords

ALCOHOL; AMPICILLIN; ASTRAGALI RADIX ETHANOL EXTRACT; ASTRAGALOSIDE I; ASTRAGALOSIDE IV; ASTRAGALUS EXTRACT; CHLORIDE; CIMETIDINE; DAUCOSTEROL; FORMONONETIN; HYDROTALCITE; SUCRALFATE; UNCLASSIFIED DRUG;

EID: 69549138020     PISSN: 19769148     EISSN: None     Source Type: Journal    
DOI: 10.4062/biomolther.2009.17.1.62     Document Type: Article
Times cited : (9)

References (37)
  • 1
    • 0033034804 scopus 로고    scopus 로고
    • In vitro anti- Helicobacter pylori activity of some flavonoids and their metabolites
    • Bae, E. A., Han M. J. and Kim, D. H. (1999). In vitro anti- Helicobacter pylori activity of some flavonoids and their metabolites. Planta. Med. 65, 442-443.
    • (1999) Planta. Med. , vol.65 , pp. 442-443
    • Bae, E.A.1    Han, M.J.2    Kim, D.H.3
  • 3
    • 34248369813 scopus 로고    scopus 로고
    • In vitro and in vivo anti-tumor effects of Astragalus membranaceus
    • DOI 10.1016/j.canlet.2006.12.001, PII S0304383506006665
    • Cho, W. C. S. and Leung, K. N. (2007a). In vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cancer. Lett. 252, 43-54. (Pubitemid 46734552)
    • (2007) Cancer Letters , vol.252 , Issue.1 , pp. 43-54
    • Cho, W.C.S.1    Leung, K.N.2
  • 4
    • 34447576629 scopus 로고    scopus 로고
    • In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus
    • DOI 10.1016/j.jep.2007.05.020, PII S0378874107002668
    • Cho, W. C. S. and Leung, K. N. (2007b). In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus. J. Ethnopharmacol. 113, 132-141. (Pubitemid 47077858)
    • (2007) Journal of Ethnopharmacology , vol.113 , Issue.1 , pp. 132-141
    • Cho, W.C.S.1    Leung, K.N.2
  • 5
    • 34548583151 scopus 로고    scopus 로고
    • Alleviation of osteoarthritis by calycosin- 7-O-beta-D-glucopyranoside (CG) isolated from Astragali radix (AR) in rabbit osteoarthritis (OA) model
    • Choi, S. I., Heo, T. R., Min, B. H., Cui, J. H., Choi, B. H. and Park, S. R. (2007). Alleviation of osteoarthritis by calycosin- 7-O-beta-D- glucopyranoside (CG) isolated from Astragali radix (AR) in rabbit osteoarthritis (OA) model. Osteoarthr. Cartil. 15, 1086-1092.
    • (2007) Osteoarthr. Cartil. , vol.15 , pp. 1086-1092
    • Choi, S.I.1    Heo, T.R.2    Min, B.H.3    Cui, J.H.4    Choi, B.H.5    Park, S.R.6
  • 6
    • 0031862831 scopus 로고    scopus 로고
    • Reactive oxygen species activity and lipid peroxidation in Helicobacter pylori associated gastritis: Relation to gastric mucosal ascorbic acid concentrations and effect of H. pylori eradication
    • Drake, I. M., Mapstone, N. P., Schorah, C. J., White, K. L., Chalmers, D. M., Dixon, M. F. and Axon, A. T. (1998). Reactive oxygen species activity and lipid peroxidation in Helicobacter pylori associated gastritis: relation to gastric mucosal ascorbic acid concentrations and effect of H. pylori eradication. Gut 42, 768-771.
    • (1998) Gut , vol.42 , pp. 768-771
    • Drake, I.M.1    Mapstone, N.P.2    Schorah, C.J.3    White, K.L.4    Chalmers, D.M.5    Dixon, M.F.6    Axon, A.T.7
  • 8
    • 33750148431 scopus 로고    scopus 로고
    • Helicobacter pylori and antimicrobial resistance: Molecular mechanisms and clinical implications
    • DOI 10.1016/S1473-3099(06)70627-2, PII S1473309906706272
    • Gerrits, M. M., van Vliet, A. H. M., Kuipers, E. J. and Kusters, J. G. (2006). Helicobacter pylori and antimicrobial resistance: molecular mechanisms and clinical implications. Lancet Infect. Dis. 6, 699-709. (Pubitemid 44601991)
    • (2006) Lancet Infectious Diseases , vol.6 , Issue.11 , pp. 699-709
    • Gerrits, M.M.1    Van Vliet, A.H.2    Kuipers, E.J.3    Kusters, J.G.4
  • 9
    • 29144460636 scopus 로고    scopus 로고
    • Effects and mechanisms of crude astragalosides fraction on liver fibrosis in rats
    • DOI 10.1016/j.jep.2005.07.025, PII S0378874105005155
    • Gui, S. Y., Wei, W., Wang, H., Wu, L., Sun, W. Y., Chen, W. B. and Wu, C. Y. (2006). Effects and mechanisms of crude astragalosides fraction on liver fibrosis in rats. J. Ethnopharmacol. 103, 154-159. (Pubitemid 41796911)
    • (2006) Journal of Ethnopharmacology , vol.103 , Issue.2 , pp. 154-159
    • Gui, S.-Y.1    Wei, W.2    Wang, H.3    Wu, L.4    Sun, W.-Y.5    Chen, W.-B.6    Wu, C.-Y.7
  • 10
    • 11844261473 scopus 로고    scopus 로고
    • Gastric mucosal protection: From prostaglandins to gene-therapy
    • Gyires, K. (2005). Gastric mucosal protection: from prostaglandins to gene-therapy. Curr. Med. Chem. 12, 203-215. (Pubitemid 40089834)
    • (2005) Current Medicinal Chemistry , vol.12 , Issue.2 , pp. 203-215
    • Gyires, K.1
  • 11
    • 0027977250 scopus 로고
    • Astragalosides from hairy root cultures of Astragalus membranaceus
    • DOI 10.1016/S0031-9422(00)89793-9
    • Hirotani, M., Zhou, Y., Rui, H. and Furuya, T. (1994). Astragalosides from hairy root cultures of Astragalus membranaceus. Phytochemistry 36, 665-670. (Pubitemid 2097623)
    • (1994) Phytochemistry , vol.36 , Issue.3 , pp. 665-670
    • Hirotani, M.1    Zhou, Y.2    Lui, H.3    Furuya, T.4
  • 12
    • 0037291541 scopus 로고    scopus 로고
    • The antioxidative and antihistaminic properties of quercetin in ethanol-induced gastric lesions
    • DOI 10.1016/S0300-483X(02)00514-0, PII S0300483X02005140
    • Kahraman, A., Erkasap, N., Koken, T., Serteser, M., Aktepe, F. and Erkasap, S. (2003). The antioxidative and antihistaminic properties of quercetin in ethanol-induced gastric lesions. Toxicology 183, 133-142. (Pubitemid 36007808)
    • (2003) Toxicology , vol.183 , Issue.1-3 , pp. 133-142
    • Kahraman, A.1    Erkasap, N.2    Koken, T.3    Serteser, M.4    Aktepe, F.5    Erkasap, S.6
  • 13
    • 0037506894 scopus 로고    scopus 로고
    • Mixed-infection of antibiotic susceptible and resistant Helicobacter pylori isolates in a single patient and underestimation of antimicrobial susceptibility testing
    • Kim, J. J., Kim, J. G. and Kwon, D. H. (2003). Mixed-infection of antibiotic susceptible and resistant Helicobacter pylori isolates in a single patient and underestimation of antimicrobial susceptibility testing. Helicobacter 8, 202-206.
    • (2003) Helicobacter , vol.8 , pp. 202-206
    • Kim, J.J.1    Kim, J.G.2    Kwon, D.H.3
  • 14
    • 0030440342 scopus 로고    scopus 로고
    • A study on the constituents from the roots of Astragalus membranaceus
    • Kim, J. S., Kim, Y. T. and Kim, C. S. (1996). A study on the constituents from the roots of Astragalus membranaceus. Kor. J. Pharmacogn. 27, 336-341.
    • (1996) Kor. J. Pharmacogn. , vol.27 , pp. 336-341
    • Kim, J.S.1    Kim, Y.T.2    Kim, C.S.3
  • 15
    • 0022486983 scopus 로고
    • A simple method for estimation of gastric mucus and effects of antiulcerogenic agents on the decrease in mucus during water-immersion stress in rats
    • Kitagawa, H., Takeda, F. and Kohei, H. (1986). A simple method for estimation of gastric mucus and effects of antiulcerogenic agents on the decrease in mucus during water-immersion stress in rats. Arzneimittel Forschung 36, 1240-1244. (Pubitemid 16035241)
    • (1986) Arzneimittel-Forschung/Drug Research , vol.36 , Issue.8 , pp. 1240-1244
    • Kitagawa, H.1    Takeda, F.2    Kohei, H.3
  • 16
    • 0033947733 scopus 로고    scopus 로고
    • Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions
    • La Casa, C., Villegas, I., Alarcón de la Lastra, C., Motilva, V. and Martín Calero, M. J. (2000). Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions. J. Ethnopharmacol. 71, 45-53.
    • (2000) J. Ethnopharmacol. , vol.71 , pp. 45-53
    • La Casa, C.1    Villegas, I.2    Alarcón De La Lastra, C.3    Motilva, V.4    Martín Calero, M.J.5
  • 17
    • 34247177491 scopus 로고    scopus 로고
    • Immunoregulatory activity by daucosterol, a β-sitosterol glycoside, induces protective Th1 immune response against disseminated Candidiasis in mice
    • Lee, J. H., Lee, J. Y., Park, J. H., Jung, H. S., Kim, J. S., Kang, S. S., Kim Y. S. and Han Y. M. (2007). Immunoregulatory activity by daucosterol, a β-sitosterol glycoside, induces protective Th1 immune response against disseminated Candidiasis in mice. Vaccine 25, 3834-3840.
    • (2007) Vaccine , vol.25 , pp. 3834-3840
    • Lee, J.H.1    Lee, J.Y.2    Park, J.H.3    Jung, H.S.4    Kim, J.S.5    Kang, S.S.6    Kim, Y.S.7    Han, Y.M.8
  • 20
    • 33847688982 scopus 로고    scopus 로고
    • The immunotherapeutic effects of Astragalus polysaccharide in type 1 diabetic mice
    • DOI 10.1248/bpb.30.470
    • Li, R. J., Qiu, S. D., Chen, H. X., Tian, H. and Wang, H. X. (2007). The Immunotherapeutic effects of Astragalus polysaccharide in type 1 diabetic mice. Biol. Pharm. Bull. 30, 470-476. (Pubitemid 46355927)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.3 , pp. 470-476
    • Li, R.-J.1    Qiu, S.-D.2    Chen, H.-X.3    Tian, H.4    Wang, H.-X.5
  • 21
    • 2942596217 scopus 로고    scopus 로고
    • Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia
    • DOI 10.1016/j.neulet.2004.03.036, PII S0304394004003362
    • Luo, Y., Qin, Z., Hong, Z., Zhang, X., Ding, D., Fu, J. H., Zhang, W. D. and Chen, J. (2004). Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia. Neurosci. Lett. 363, 218-223. (Pubitemid 38746516)
    • (2004) Neuroscience Letters , vol.363 , Issue.3 , pp. 218-223
    • Luo, Y.1    Qin, Z.2    Hong, Z.3    Zhang, X.4    Ding, D.5    Fu, J.-H.6    Zhang, W.-D.7    Chen, J.8
  • 22
    • 33645963448 scopus 로고    scopus 로고
    • Helicobacter pylori infection and gastric cancer
    • Matysiak-Budnik, T. and Megraud, F. (2006). Helicobacter pylori infection and gastric cancer. Eur. J. Cancer 42, 708-716.
    • (2006) Eur. J. Cancer , vol.42 , pp. 708-716
    • Matysiak-Budnik, T.1    Megraud, F.2
  • 23
    • 0020503472 scopus 로고
    • Effect of polyamines on acidified ethanol-induced gastric lesion in rats
    • Mizui, T. and Dodeuchi, M. (1983). Effect of polyamines on acidified ethanol-induced gastric lesion in rats. Jpn. J. Pharmacol. 33, 939-945.
    • (1983) Jpn. J. Pharmacol. , vol.33 , pp. 939-945
    • Mizui, T.1    Dodeuchi, M.2
  • 24
    • 22844435412 scopus 로고    scopus 로고
    • Gastroprotective effect of Astragaloside IV: Role of prostaglandins, sulfhydryls and nitric oxide
    • DOI 10.1211/0022357056659
    • Navarrete, A., Arrieta, J., Terrones, L., Abou-Gazar, H. and Calis, I. (2005). Gastroprotective effect of Astragaloside IV: role of prostaglandins, sulfhydryls and nitric oxide. J. Pharm. Pharmacol. 57, 1059-1064. (Pubitemid 41039842)
    • (2005) Journal of Pharmacy and Pharmacology , vol.57 , Issue.8 , pp. 1059-1064
    • Navarrete, A.1    Arrieta, J.2    Terrones, L.3    Abou-Gazar, H.4    Calis, I.5
  • 27
    • 0030797894 scopus 로고    scopus 로고
    • A review of the pharmacology and toxicology of Astragalus
    • Ríos, J. L. and Waterman, P. G. (1997). A review of the pharmacology and toxicology of Astragalus. Phytother. Res. 11, 411-418.
    • (1997) Phytother. Res. , vol.11 , pp. 411-418
    • Ríos, J.L.1    Waterman, P.G.2
  • 29
    • 3142684519 scopus 로고    scopus 로고
    • A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb
    • DOI 10.1016/j.bbrc.2004.06.065, PII S0006291X04013129
    • Shao, B. M., Xu, W., Dai, H., Tu, P., Li, Z. and Gao, X. M. (2004). A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. Biochem. Biophys. Res. Commun. 320, 1103-1111. (Pubitemid 38916657)
    • (2004) Biochemical and Biophysical Research Communications , vol.320 , Issue.4 , pp. 1103-1111
    • Shao, B.-M.1    Xu, W.2    Dai, H.3    Tu, P.4    Li, Z.5    Gao, X.-M.6
  • 30
    • 0002370577 scopus 로고
    • A simple method for the uniform production of gastric ulceration in the rat
    • Shay, H., Komarov, S. A., Fels, S. S. and Meranze, D. (1945). A simple method for the uniform production of gastric ulceration in the rat. Gastroenterology 4, 43-61.
    • (1945) Gastroenterology , vol.4 , pp. 43-61
    • Shay, H.1    Komarov, S.A.2    Fels, S.S.3    Meranze, D.4
  • 31
    • 34247122414 scopus 로고    scopus 로고
    • Screening of the antioxidative properties and total phenolic contents of three endemic Tanacetum subspecies from Turkish flora
    • DOI 10.1016/j.biortech.2006.10.019, PII S0960852406005748
    • Tepe, B. and Sokmen, A. (2007). Screening of the antioxidative properties and total phenolic contents of three endemic Tanacetum subspecies from Turkish flora. Bioresour. Technol. 98, 3076-3079. (Pubitemid 46603260)
    • (2007) Bioresource Technology , vol.98 , Issue.16 , pp. 3076-3079
    • Tepe, B.1    Sokmen, A.2
  • 32
    • 34447345960 scopus 로고    scopus 로고
    • Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft
    • DOI 10.1093/carcin/bgl238
    • Tin, M. M. Y., Cho, C. H., Chan, K., James, A. E. and Ko, J. K. S. (2007). Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft. Carcinogenesis 28, 1347-1355. (Pubitemid 47062696)
    • (2007) Carcinogenesis , vol.28 , Issue.6 , pp. 1347-1355
    • Tin, M.M.Y.1    Cho, C.2    Chan, K.3    James, A.E.4    Ko, J.K.S.5
  • 33
    • 33750459861 scopus 로고    scopus 로고
    • Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus
    • DOI 10.1038/sj.bjp.0706865, PII 0706865
    • Tohda, C., Tamura, T., Matsuyama, S. and Komatsu, K. (2006). Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus. Br. J. Pharmacol. 149, 532-541. (Pubitemid 44658514)
    • (2006) British Journal of Pharmacology , vol.149 , Issue.5 , pp. 532-541
    • Tohda, C.1    Tamura, T.2    Matsuyama, S.3    Komatsu, K.4
  • 34
    • 0025817861 scopus 로고
    • Cell mediated cytotoxicity against U 937 cells by human monocytes and macrophages in a modified colorimetric MTT assay. A methodological study
    • van de Loosdrecht, A. A., Nennie, E., Ossenkoppele, G. J., Beelen, R. H. and Langenhuijsen, M. M. (1991). Cell mediated cytotoxicity against U 937 cells by human monocytes and macrophages in a modified colorimetric MTT assay. A methodological study. J. Immunol. Methods 141, 15-22.
    • (1991) J. Immunol. Methods , vol.141 , pp. 15-22
    • Van De Loosdrecht, A.A.1    Nennie, E.2    Ossenkoppele, G.J.3    Beelen, R.H.4    Langenhuijsen, M.M.5
  • 35
    • 32644451004 scopus 로고    scopus 로고
    • Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro
    • DOI 10.1055/s-2005-873126
    • Zhang, W. D., Chen, H., Zhang, C., Liu, R. H., Li, H. L. and Chen, H. Z. (2006a). Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro. Planta Med. 72, 4-8. (Pubitemid 43241585)
    • (2006) Planta Medica , vol.72 , Issue.1 , pp. 4-8
    • Zhang, W.-D.1    Chen, H.2    Zhang, C.3    Liu, R.-H.4    Li, H.-L.5    Chen, H.-Z.6
  • 36
    • 33745663269 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics and tissue distribution of a natural cardioprotective agent astragaloside IV in rats and dogs
    • DOI 10.1016/j.lfs.2006.02.032, PII S0024320506002098
    • Zhang, W. D., Zhang, C., Liu, R. H., Li, H. L., Zhang, J. T., Mao, C., Moran, S. and Chen, C. L. (2006b). Preclinical pharmacokinetics and tissue distribution of a natural cardioprotective agent astragaloside IV in rats and dogs. Life Sci. 79, 808-815. (Pubitemid 43975129)
    • (2006) Life Sciences , vol.79 , Issue.8 , pp. 808-815
    • Zhang, W.-D.1    Zhang, C.2    Liu, R.-H.3    Li, H.-L.4    Zhang, J.-T.5    Mao, C.6    Moran, S.7    Chen, C.-L.8
  • 37
    • 0242606426 scopus 로고    scopus 로고
    • Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression
    • Zhang, W. J., Hufnag, P., Binder, B. R. and Wojta, J. (2003). Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression. Thromb. Haemost. 90, 904-914.
    • (2003) Thromb. Haemost. , vol.90 , pp. 904-914
    • Zhang, W.J.1    Hufnag, P.2    Binder, B.R.3    Wojta, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.