Co-treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells

Cell Proliferation

Volumn 42, Issue 5, 2009, Pages 701-709

  Fujii, K ^a   Luo, Y ^a   Sasahira, T ^a   Denda, A ^a   Ohmori, H ^a   Kuniyasu, H ^a  

^a NARA MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; DEOXYCHOLIC ACID; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE H4; MESSENGER RNA;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL LINE; CELL NUCLEUS; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; INTESTINE EPITHELIUM CELL; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN LOCALIZATION; PROTEIN SECRETION; RAT; UPREGULATION;

ACETYLATION; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; AZOXYMETHANE; CARCINOGENS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CHOLAGOGUES AND CHOLERETICS; COLON; DEOXYCHOLIC ACID; ENZYME INHIBITORS; EPITHELIAL CELLS; FATTY ACIDS, UNSATURATED; HISTONES; HMGB1 PROTEIN; HYDROXAMIC ACIDS; INTESTINAL MUCOSA; MALE; RATS; RATS, INBRED F344; RNA, MESSENGER; UP-REGULATION;

EID: 69549112973     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2009.00624.x     Document Type: Article

References (48)

1. Goodwin GH, Sanders C, Johns EW (1973) A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur. J. Biochem. 38, 14 19.
2. Pasheva EA, Ugrinova I, Spassovska N, Pashev IG (2002) The binding affinity of HMG1 protein to DNA modified by cis-platin and its analogs correlates with their antitumor activity. Int. J. Biochem. Cell Biol. 34, 87 92.
3. Stros M, Ozaki T, Bacikova A, Kageyama H, Nakagawara A (2002) HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoter. J. Biol. Chem. 277, 7157 7164.
4. Ugrinova I, Pasheva EA, Armengaud J, Pashev IG (2001) In vivo acetylation of HMG1 protein enhances its binding affinity to distorted DNA structures. Biochemistry 40, 14655 14660.
5. Poser I, Golob M, Buettner R, Bosserhoff AK (2003) Upregulation of HMG1 leads to melanoma inhibitory activity expression in malignant melanoma cells and contributes to their malignancy phenotype. Mol. Cell. Biol. 23, 2991 2998.
6. Sasahira T, Kirita T, Oue N, Bhawal UK, Yamamoto K, Fujii K, Ohmori H, Luo Y, Yasui W, Bosserhoff AK, Kuniyasu H (2008) High mobility group box-1-inducible melanoma inhibitory activity is associated with nodal metastasis and lymphangiogenesis in oral squamous cell carcinoma. Cancer Sci. 99, 1806 1812.
7. Calogero S, Grassi F, Aguzzi A, Voigtlander T, Ferrier P, Ferrari S, Bianchi ME (1999) The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice. Nat. Genet. 22, 276 280.
8. Huttunen HJ, Kuja-Panula J, Sorci G, Agneletti AL, Donato R, Rauvala H (2000) Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation. J. Biol. Chem. 275, 40096 40105.
9. Parkkinen J, Raulo E, Merenmies J, Nolo R, Kajander EO, Baumann M, Rauvala H (1993) Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation. J. Biol. Chem. 268, 19726 19738.
10. Andersson U, Erlandsson-Harris H, Yang H, Tracey KJ (2002) HMGB1 as a DNA-binding cytokine. J. Leukoc Biol. 72, 1084 1091.
11. Kim JY, Park JS, Strassheim D, Douglas I, Diaz del Valle F, Asehnoune K, Mitra S, Kwak SH, Yamada S, Maruyama I, Ishizaka A, Abraham E (2005) HMGB1 contributes to the development of acute lung injury after hemorrhage. Am. J. Physiol. Lung Cell. Mol. Physiol. 288, L958 L965.
12. Yang H, Wang H, Tracey KJ (2001) HMG-1 rediscovered as a cytokine. Shock 15, 247 253.
13. Yang H, Wang H, Czura CJ, Tracey KJ (2002) HMGB1 as a cytokine and therapeutic target. J. Endotoxin Res. 8, 469 472.
14. Tang D, Shi Y, Jang L, Wang K, Xiao W, Xiao X (2005) Heat shock response inhibits release of high mobility group box 1 protein induced by endotoxin in murine macrophages. Shock 23, 434 440.
15. Watanabe T, Kubota S, Nagaya M, Ozaki S, Nagafuchi H, Akashi K, Taira Y, Tsukikawa S, Oowada S, Nakano S (2005) The role of HMGB-1 on the development of necrosis during hepatic ischemia and hepatic ischemia/reperfusion injury in mice. J. Surg. Res. 124, 59 66.
16. Bhawal UK, Ozaki Y, Nishimura M, Sugiyama M, Sasahira T, Nomura Y, Sato F, Fujimoto K, Sasaki N, Ikeda M, Tsuji K, Kuniyasu H, Kato Y (2005) Association of expression of receptor for advanced glycation end products and invasive activity of oral squamous cell carcinoma. Oncology 69, 246 255.
17. Kuniyasu H, Oue N, Wakikawa A, Shigeishi H, Matsutani N, Kuraoka K, Ito R, Yokozaki H, Yasui W (2002) Expression of receptors for advanced glycation end-products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer. J. Pathol. 196, 163 170.
18. Kuniyasu H, Chihara Y, Takahashi T (2003) Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer. Oncol. Rep. 10, 445 448.
19. Kuniyasu H, Sasaki T, Sasahira T, Ohmori H, Takahashi T (2004) Depletion of tumor-infiltrating macrophages is associated with amphoterin expression in colon cancer. Pathobiology 71, 129 136.
20. Sasahira T, Akama Y, Fujii K, Kuniyasu H (2005) Expression of receptor for advanced glycation end products and HMGB1/amphoterin in colorectal adenomas. Virchows Arch. 446, 411 415. (Pubitemid 40674848)
21. Sasahira T, Sasaki T, Kuniyasu H (2005) Interleukin-15 and transforming growth factor alpha are associated with depletion of tumor-associated macrophages in colon cancer. J. Exp. Clin. Cancer Res. 24, 69 74.
22. Sasahira T, Kirita T, Bhawal UK, Yamamoto K, Kuniyasu H (2007) Receptor for advanced glycation end products (RAGE) is important in the prediction of recurrence in human oral squamous cell carcinoma. Histopathology 51, 166 172. (Pubitemid 47083983)
23. Kuniyasu H, Yano S, Sasaki T, Sasahira T, Sone S, Ohmori H (2005) Colon cancer cell-derived high mobility group 1/amphoterin induces growth inhibition and apoptosis in macrophages. Am. J. Pathol. 166, 751 760.
24. Andersson U, Erlandsson-Harris H (2004) HMGB1 is a potent trigger of arthritis. J. Intern. Med. 255, 344 350.
25. Huttunen HJ, Rauvala H (2004) Amphoterin as an extracellular regulator of cell motility: from discovery to disease. J. Intern. Med. 255, 351 366.
26. Wang H, Yang H, Tracey KJ (2004) Extracellular role of HMGB1 in inflammation and sepsis. J. Intern. Med. 255, 320 331.
27. Czura CJ, Wang H, Tracey KJ (2001) Dual roles for HMGB1: DNA binding and cytokine. J. Endotoxin Res. 7, 315 321.
28. Bonaldi T, Talamo F, Scaffidi P, Ferrera D, Porto A, Bachi A, Rubartelli A, Agresti A, Bianchi ME (2003) Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J. 22, 5551 5560.
29. Gardella S, Andrei C, Ferrera D, Lotti LV, Torrisi MR, Bianchi ME, Rubartelli A (2002) The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway. EMBO Rep. 3, 995 1001.
30. Kuniyasu H, Yasui W, Shinohara H, Yano S, Ellis LM, Wilson MR, Bucana CD, Rikita T, Tahara E, Fidler IJ (2000) Induction of angiogenesis by hyperplastic colonic mucosa adjacent to colon cancer. Am. J. Pathol. 157, 1523 1535.
31. Feinberg A, Zedeck MS (1980) Production of a highly reactive alkylating agent from the organospecific carcinogen methylazoxymethanol by alcohol dehydrogenase. Cancer Res. 40, 4446 4450.
32. Sohn OS, Ishizaki H, Yang CS, Fiala ES (1991) Metabolism of azoxymethane, methylazoxymethanol and N-nitrosodimethylamine by cytochrome P450IIE1. Carcinogenesis 12, 127 131.
33. Sasaki T, Yoshida K, Shimura H, Ichiba M, Sasahira T, Shimomoto T, Denda A, Kuniyasu H (2006b) Inhibitory effect of linoleic acid on transformation of IEC6 intestinal cells by in vitro azoxymethane treatment. Int. J. Cancer 118, 593 599.
34. Bartram HP, Scheppach W, Schmid H, Hofmann A, Dusel G, Richter F, Richter A, Kasper H (1993) Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenesis: effects of butyrate, deoxycholate, calcium, ammonia, and pH. Cancer Res. 53, 3283 3288.
35. Narisawa T, Magadia NE, Weisburger JH, Wynder EL (1974) Promoting effect of bile acids on colon carcinogenesis after intrarectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine in rats. J. Natl. Cancer Inst. 53, 1093 1097.
36. Peiffer LP, Peters DJ, McGarrity TJ (1997) Differential effects of deoxycholic acid on proliferation of neoplastic and differentiated colonocytes in vitro. Dig. Dis. Sci. 42, 2234 2240.
37. Reddy BS, Watanabe K, Weisburger JH, Wynder EL (1977) Promoting effect of bile acids in colon carcinogenesis in germ-free and conventional F344 rats. Cancer Res. 37, 3238 3242. (Pubitemid 8169906)
38. Sasaki T, Sasahira T, Shimura H, Ikeda S, Kuniyasu H (2005) High concentration of deoxycholic acid abrogates in vitro transformation of IEC6 intestinal cells by azoxymethane. J. Exp. Clin. Cancer Res. 24, 207 213.
39. Sutherland LA, Bird RP (1994) The effect of chenodeoxycholic acid on the development of aberrant crypt foci in the rat colon. Cancer Lett. 76, 101 107.
40. Conteas CN, Majumdar AP (1987) The effects of gastrin, epidermal growth factor, and somatostatin on DNA synthesis in a small intestinal crypt cell line (IEC-6). Proc. Soc. Exp. Biol. Med. 184, 307 311.
41. Quaroni A, Isselbacher KJ, Ruoslahti E (1978) Fibronectin synthesis by epithelial crypt cells of rat small intestine. Proc. Natl. Acad. Sci. USA 75, 5548 5552.
42. Kuniyasu H, Yasui W, Kitahara K, Naka K, Yokozaki H, Akama Y, Hamamoto T, Tahara H, Tahara E (1997) Growth inhibitory effect of interferon-beta is associated with the induction of cyclin-dependent kinase inhibitor p27Kip1 in a human gastric carcinoma cell line. Cell Growth Differ. 8, 47 52.
43. Sasaki T, Fujii K, Yoshida K, Shimura H, Sasahira T, Ohmori H, Kuniyasu H (2006) Peritoneal metastasis inhibition by linoleic acid with activation of PPARγ in human gastrointestinal cancer cells. Virchows Arch. 448, 422 427.
44. Lange SS, Mitchell DL, Vasquez KM (2008) High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage. Proc. Natl. Acad. Sci. USA 105, 10320 10325.
45. Scaffidi P, Misteli T, Bianchi ME (2002) Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418, 191 195.
46. Liu S, Stolz DB, Sappington PL, Macias CA, Killeen ME, Tenhunen JJ, Delude RL, Fink MP (2006) HMGB1 is secreted by immunostimulated enterocytes and contributes to cytomix-induced hyperpermeability of Caco-2 monolayers. Am. J. Physiol. Cell Physiol. 290, C990 C999.
47. Cheng BQ, Jia CQ, Liu CT, Lu XF, Zhong N, Zhang ZL, Fan W, Li YQ (2008) Serum high mobility group box chromosomal protein 1 is associated with clinicopathologic features in patients with hepatocellular carcinoma. Dig. Liver Dis. 40, 446 452.
48. Meyer A, Staratschek-Jox A, Springwald A, Wenk H, Wolf J, Wickenhauser C, Bullerdiek J (2008) Non-Hodgkin lymphoma expressing high levels of the danger-signalling protein HMGB1. Leuk. Lymphoma. 49, 1184 1189.