The binding affinity of HMG1 protein to DNA modified by cis-platin and its analogs correlates with their antitumor activity

International Journal of Biochemistry and Cell Biology

Volumn 34, Issue 1, 2002, Pages 87-92

  Pasheva, Evdokia A ^a   Ugrinova, Iva ^a   Spassovska, Nadejda C ^a   Pashev, Iliya G ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY   (Bulgaria)

Author keywords

Antitumor activity; Cis platin analogs; Cis platin damaged DNA; HMG1 protein

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISAMMINE(CYCLOHEXANECARBOXYLIC ACID HYDRAZIDE)DICHLOROPLATINUM 2; CISAMMINE(CYCLOPENTANECARBOXYLIC ACID HYDRAZIDE)DICHLOROPLATINUM 2; CISPLATIN; CISPLATIN DERIVATIVE; DNA; HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP PROTEIN; PLATINUM COMPLEX; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CORRELATION FUNCTION; DISSOCIATION CONSTANT; DNA ADDUCT; DNA PROBE; DNA REPAIR; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG SCREENING; GEL MOBILITY SHIFT ASSAY; NONHUMAN; PROTEIN DNA BINDING;

ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; CISPLATIN; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; DRUG SCREENING ASSAYS, ANTITUMOR; HMGB1 PROTEIN; KINETICS; PROTEIN BINDING;

EID: 0036133706     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(01)00096-6     Document Type: Article

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