Non-Hodgkin lymphoma expressing high levels of the danger-signalling protein HMGB1

Leukemia and Lymphoma

Volumn 49, Issue 6, 2008, Pages 1184-1189

  Meyer, Anke ^a   Staratschek Jox, Andrea ^b   Springwald, Anette ^a   Wenk, Heiner ^c   Wolf, Jurgen ^b   Wickenhauser, Claudia ^b   Bullerdiek, Jorn ^a,d  

^a UNIVERSITY OF BREMEN   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c Clinical Center Bremen Nord   (Germany)

^d UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Angiogenesis; HMGB1; Non Hodgkin lymphoma; Quantitative real time RT PCR

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; MESSENGER RNA;

ARTICLE; CANCER GRADING; CELL GROWTH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHANGIOGENESIS; LYMPHOMA CELL LINE; NONHODGKIN LYMPHOMA; NUCLEOTIDE SEQUENCE; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR VASCULARIZATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; FEMALE; HMGB1 PROTEIN; HUMANS; LYMPH NODES; LYMPHOMA, NON-HODGKIN; MALE; MIDDLE AGED; NECROSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TUMOR CELLS, CULTURED;

EID: 46749122352     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190802064909     Document Type: Article

References (26)

1. Goodwin, G. H., Sanders, C. and Johns, E. W. (1973) A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur J Biochem, 38, pp. 14-19.
2. Parkkinen, J., Raulo, E., Merenmies, J., Nolo, R., Kajander, E. O., Baumann, M. and Rauvala, H. (1993) Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation. J Biol Chem, 268, pp. 19726-19738.
3. Degryse, B., Bonaldi, T., Scaffidi, P., Muller, S., Resnati, M. Sanvito, F. et al. (2001) The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J Cell Biol, 152, pp. 1197-1206.
4. Wang, H., Bloom, O., Zhang, M., Vishnubhakat, J. M., Ombrellino, M. Che, J. et al. (1999) HMG-1 as a late mediator of endotoxin lethality in mice. Science, 285, pp. 248-251.
5. Gratzinger, D., Zhao, S., Marinelli, R. J., Kapp, A. V., Tibshirani, R. J. Hammer, A. S. et al. (2007) Microvessel density and expression of vascular endothelial growth factor and its receptors in diffuse large B-cell lymphoma subtypes. Am J Pathol, 170, pp. 1362-1369.
6. Schlueter, C., Weber, H., Meyer, B., Rogalla, P., Roser, K., Hauke, S. and Bullerdiek, J. (2005) Angiogenetic signaling through hypoxia: HMGB1: an angiogenetic switch molecule. Am J Pathol, 166, pp. 1259-1263.
7. Mitola, S., Belleri, M., Urbinati, C., Coltrini, D., Sparatore, B. Pedrazzi, M. et al. (2006) Cutting edge: Extracellular high mobility group box-1 protein is a proangiogenic cytokine. J Immunol, 176, pp. 12-15.
8. Kuniyasu, H., Yano, S., Sasaki, T., Sasahira, T., Sone, S. and Ohmori, H. (2005) Colon cancer cell-derived high mobility group 1/amphoterin induces growth inhibition and apoptosis in macrophages. Am J Pathol, 166, pp. 751-760.
9. Taguchi, A., Blood, D. C., del Toro, G, Canet, A., Lee, D. C. Qu, W. et al. (2000) Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases. Nature, 405, pp. 354-360.
10. Zeh 3rd, H. J. and Lotze, M. T. (2005) Addicted to death: Invasive cancer and the immune response to unscheduled cell death. J Immunother, 28, pp. 1-9.
11. Antonov, J., Goldstein, D. R., Oberli, A., Baltzer, A., Pirotta, M. Fleischmann, A. et al. (2005) Reliable gene expression measurements from degraded RNA by quantitative real-time PCR depend on short amplicons and a proper normalization. Lab Invest, 85, pp. 1040-1050.
12. Rogalla, P., Kazmierczak, B., Flohr, A. M., Hauke, S. and Bullerdiek, J. (2000) Back to the roots of a new exon-the molecular archaeology of a SP100 splice variant. Genomics, 63, pp. 117-122.
13. Strichman-Almashanu, L. Z., Bustin, M. and Landsman, D. (2003) Retroposed copies of the HMG genes: A window to genome dynamics. Genome Res, 13, pp. 800-812.
14. Rauvala, H., Huttunen, H. J., Fages, C., Kaksonen, M., Kinnunen, T. Imai, S. et al. (2000) Heparin-binding proteins HB-GAM (pleiotrophin) and amphoterin in the regulation of cell motility. Matrix Biol, 19, pp. 377-387.
15. van Beijnum, J. R., Dings, R. P., van der Linden, E., Zwaans, B. M., Ramaekers, F. C. Mayo, K. H. et al. (2006) Gene expression of tumor angiogenesis dissected: Specific targeting of colon cancer angiogenic vasculature. Blood, 108, pp. 2339-2348.
16. Volp, K., Brezniceanu, M. L., Bosser, S., Brabletz, T., Kirchner, T. Gottel, D. et al. (2006) Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas. Gut, 55, pp. 234-242.
17. Yu, J., Mallon, M. A., Zhang, W., Freimuth, R. R., Marsh, S. Watson, M. A. et al. (2006) DNA repair pathway profiling and microsatellite instability in colorectal cancer. Clin Cancer Res, 12, pp. 5104-5111.
18. Xiang, Y. Y., Wang, D. Y., Tanaka, M., Suzuki, M., Kiyokawa, E. Igarashi, H. et al. (1997) Expression of high-mobility group-1 mRNA in human gastrointestinal adenocarcinoma and corresponding non-cancerous mucosa. Int J Cancer, 74, pp. 1-6.
19. Oue, N., Aung, P. P., Mitani, Y., Kuniyasu, H., Nakayama, H. and Yasui, W. (2005) Genes involved in invasion and metastasis of gastric cancer identified by array-based hybridization and serial analysis of gene expression. Oncology, 69, pp. 17-22.
20. Flohr, A. M., Rogalla, P., Meiboom, M., Borrmann, L., Krohn, M. Thode-Halle, B. et al. (2001) Variation of HMGB1 expression in breast cancer. Anticancer Res, 21, pp. 3881-3885.
21. Brezniceanu, M. L., Volp, K., Bosser, S., Solbach, C., Lichter, P. Joos, S. et al. (2003) HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma. Faseb J, 17, pp. 1295-1297.
22. Kawahara, N., Tanaka, T., Yokomizo, A., Nanri, H., Ono, M. Wada, M. et al. (1996) Enhanced coexpression of thioredoxin and high mobility group protein 1 genes in human hepatocellular carcinoma and the possible association with decreased sensitivity to cisplatin. Cancer Res, 56, pp. 5330-5333.
23. Kuniyasu, H., Chihara, Y., Kondo, H., Ohmori, H. and Ukai, R. (2003) Amphoterin induction in prostatic stromal cells by androgen deprivation is associated with metastatic prostate cancer. Oncol Rep, 10, pp. 1863-1868.
24. Poser, I., Golob, M., Buettner, R. and Bosserhoff, A. K. (2003) Upregulation of HMG1 leads to melanoma inhibitory activity expression in malignant melanoma cells and contributes to their malignancy phenotype. Mol Cell Biol, 23, pp. 2991-2998.
25. Scaffidi, P., Misteli, T. and Bianchi, M. E. (2002) Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature, 418, pp. 191-195.
26. Zhang, C. L., Shu, M. G., Qi, H. W. and Li, L. W. (2008) Inhibition of tumor angiogenesis by HMGB1 A box peptide. Med Hypotheses, 70, pp. 343-345.