Inhibition of metalloproteinase-9 activity and gene expression by polyphenolic compounds isolated from the bark of Tristaniopsis calobuxus (Myrtaceae)

Cellular and Molecular Life Sciences

Volumn 60, Issue 7, 2003, Pages 1440-1448

  Bellosta, S ^a   Dell'Agli, M ^a   Canavesi, M ^a   Mitro, N ^a   Monetti, M ^a   Crestani, M ^a   Verotta, L ^a   Fuzzati, N ^b   Bernini, F ^c   Bosisio, E ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b INDENA S P A   (Italy)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

(+) gallocatechin; ( ) epigallocatechin; ( ) gallocatechin; Ellagic acid; Gene expression; Metalloproteinase 9; Plant polyphenols; Secretion; Tristaniopsis calobuxus

Indexed keywords

ELLAGIC ACID; EPIGALLOCATECHIN; GALLOCATECHIN; GELATINASE B; GLYCOSIDE; MESSENGER RNA; PLANT EXTRACT; POLYPHENOL DERIVATIVE; TRISTANIOPSIS CALOBUXUS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARTILAGE DEGENERATION; CONCENTRATION RESPONSE; DERIVATIZATION; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOUSE; MYRTACEAE; NONHUMAN; PERITONEUM MACROPHAGE; PROMOTER REGION; VASCULAR SMOOTH MUSCLE;

ANIMALS; FLAVONOIDS; GENE EXPRESSION REGULATION; GENES, REPORTER; KINETICS; MACROPHAGES, PERITONEAL; MAGNETIC RESONANCE SPECTROSCOPY; MATRIX METALLOPROTEINASE 9; MICE; MYRTACEAE; PHENOLS; PLANT BARK; PLANT EXTRACTS; POLYMERS; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; RNA, MESSENGER; SIMIAN VIRUS 40; TRANSFECTION;

ANIMALIA; EUKARYOTA; MYRTACEAE; TRISTANIOPSIS;

EID: 0042869970     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-3119-3     Document Type: Article

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