Signal-transducing mechanisms of ketamine-caused inhibition of interleukin-1β gene expression in lipopolysaccharide-stimulated murine macrophage-like Raw 264.7 cells

Toxicology and Applied Pharmacology

Volumn 240, Issue 1, 2009, Pages 15-25

  Chen, Ta Liang ^a   Chang, Chia Chen ^b   Lin, Yi Ling ^a,b   Ueng, Yune Fang ^b,c   Chen, Ruei Ming ^a,b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

IL 1 ; Ketamine; Macrophages; Signal transducing mechanisms; Toll like receptor 4

Indexed keywords

CYTOKINE; DNA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; KETAMINE; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE 1; RAF PROTEIN; RAS PROTEIN; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BINDING AFFINITY; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG EXPOSURE; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; IMMUNOBLOTTING; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CELL SURVIVAL; DOWN-REGULATION; INTERLEUKIN-1BETA; KETAMINE; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

MURINAE;

EID: 69549086363     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.06.013     Document Type: Article

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