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Volumn 7, Issue 8, 2009, Pages 1408-1415

NGFI-B nuclear orphan receptor Nurr1 interacts with p53 and suppresses its transcriptional activity

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; NUCLEAR RECEPTOR NUR77; NUCLEAR RECEPTOR RELATED FACTOR 1; PROTEIN BAX; PROTEIN P53;

EID: 69449092501     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-08-0533     Document Type: Article
Times cited : (41)

References (45)
  • 1
    • 0027074637 scopus 로고
    • Identification of a new brain-specific transcription factor, NURR1
    • Law SW, Conneely OM, DeMayo FJ, O'Malley BW. Identification of a new brain-specific transcription factor, NURR1. Mol Endocrinol 1992;6:2129-2135
    • (1992) Mol Endocrinol , vol.6 , pp. 2129-2135
    • Law, S.W.1    Conneely, O.M.2    DeMayo, F.J.3    O'Malley, B.W.4
  • 2
    • 0028080267 scopus 로고
    • NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3
    • DOI 10.1210/me.8.11.1583
    • Mages HW, Rilke O, Bravo R, Senger G, Kroczek RA. NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3. Mol Endocrinol 1994;8:1583-1591 (Pubitemid 24370207)
    • (1994) Molecular Endocrinology , vol.8 , Issue.11 , pp. 1583-1591
    • Mages, H.W.1    Rilke, O.2    Bravo, R.3    Senger, G.4    Kroczek, R.A.5
  • 3
    • 0035100243 scopus 로고    scopus 로고
    • Parathyroid hormone induces expression of the nuclear orphan receptor Nurr1 in bone cells
    • DOI 10.1210/en.142.2.663
    • Tetradis S, Bezouglaia O, Tsingotjidou A. Parathyroid hormone induces expression of the nuclear orphan receptor Nurr1 in bone cells. Endocrinology 2001;142:663-670 (Pubitemid 32222415)
    • (2001) Endocrinology , vol.142 , Issue.2 , pp. 663-670
    • Tetradis, S.1    Bezouglaia, O.2    Tsingotjidou, A.3
  • 5
    • 0031018683 scopus 로고    scopus 로고
    • Differential expression of NGFI-B and RNR-1 genes in various tissues and developing brain of the rat: Comparative study by quantitative reverse transcription-polymerase chain reaction
    • DOI 10.1046/j.1365-2826.1997.00571.x
    • Bandoh S, Tsukada T, Maruyama K, Ohku ra N, Yamaguchi K. Differential expression of NGFI-B and RNR-1 genes in various tissues and developing brain of the rat: comparative study by quantitative reverse transcription-polymerase chain reaction. J Neuroendocrinol 1997;9:3-8. (Pubitemid 27042853)
    • (1997) Journal of Neuroendocrinology , vol.9 , Issue.1 , pp. 3-8
    • Bandoh, S.1    Tsukada, T.2    Maruyama, K.3    Ohkura, N.4    Yamaguchi, K.5
  • 6
    • 0032874648 scopus 로고    scopus 로고
    • Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain
    • Sakurada K, Ohshima-Sakurada M, Palmer TD, Gage FH. Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development 1999;126:4017-4026 (Pubitemid 29481559)
    • (1999) Development , vol.126 , Issue.18 , pp. 4017-4026
    • Sakurada, K.1    Ohshima-Sakurada, M.2    Palmer, T.D.3    Gage, F.H.4
  • 7
    • 0033380674 scopus 로고    scopus 로고
    • 4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors
    • DOI 10.1016/S0169-328X(99)00234-X, PII S0169328X9900234X
    • Schimmel JJ, Crews L, Roffler-Tarlov S, Chikaraishi DM. 4.5 kb of the rat tyrosine hydroxylase 5′ flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors. Brain Res Mol Brain Res 1999;74:1-14. (Pubitemid 30038174)
    • (1999) Molecular Brain Research , vol.74 , Issue.1-2 , pp. 1-14
    • Schimmel, J.J.1    Crews, L.2    Roffler-Tarlov, S.3    Chikaraishi, D.M.4
  • 8
    • 0037660209 scopus 로고    scopus 로고
    • Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell-specific manner
    • Kim KS, Kim CH, Hwang DY, et al. Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell-specific manner. J Neurochem 2003;85:622-634
    • (2003) J Neurochem , vol.85 , pp. 622-634
    • Kim, K.S.1    Kim, Ch.2    Hwang, D.Y.3
  • 10
    • 0033402407 scopus 로고    scopus 로고
    • Characterization of the 5'-flanking region of the human dopamine transporter gene
    • DOI 10.1016/S0169-328X(99)00275-2, PII S0169328X99002752
    • Sacchetti P, Brownschidle LA, Granneman JG, Bannon MJ. Characterization of the 5′-flanking region of the human dopamine transporter gene. Brain Res Mol Brain Res 1999;74:167-174 (Pubitemid 30038190)
    • (1999) Molecular Brain Research , vol.74 , Issue.1-2 , pp. 167-174
    • Sacchetti, P.1    Brownschidle, L.A.2    Granneman, J.G.3    Bannon, M.J.4
  • 12
    • 0037144591 scopus 로고    scopus 로고
    • Defining requirements for heterodimerization between the retinoid X receptor and the orphan nuclear receptor Nurr1
    • DOI 10.1074/jbc.M201707200
    • Aarnisalo P, Kim CH, Lee JW, Perlmann T. Defining requirements for heterodimerization between the retinoid X receptor and the orphan nuclear receptor Nurr1. J Biol Chem 2002;277:35118-35123 (Pubitemid 35052408)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.38 , pp. 35118-35123
    • Aarnisalo, P.1    Kim, C.-H.2    Lee, J.W.3    Perlmann, T.4
  • 13
    • 0028946634 scopus 로고
    • A novel pathway for vitamin a signaling mediated by RXR heterodimerization with NGFI-B and NURR1
    • Perlmann T, Jansson L. A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev 1995;9:769-782
    • (1995) Genes Dev , vol.9 , pp. 769-782
    • Perlmann, T.1    Jansson, L.2
  • 14
    • 0027976193 scopus 로고
    • Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate- Early gene nur77
    • Liu ZG, Smith SW, McLaughlin KA, Schwartz LM, Osborne BA. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate- early gene nur77. Nature 1994;367:281-284
    • (1994) Nature , vol.367 , pp. 281-284
    • Liu, Z.G.1    Smith, S.W.2    McLaughlin, K.A.3    Schwartz, L.M.4    Osborne, B.A.5
  • 15
    • 0028008513 scopus 로고
    • Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas
    • DOI 10.1038/367277a0
    • Woronicz JD, Calnan B, Ngo V, Winoto A. Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas. Nature 1994;367:277-281 (Pubitemid 24051144)
    • (1994) Nature , vol.367 , Issue.6460 , pp. 277-281
    • Woronicz, J.D.1    Calnan, B.2    Ngo, V.3    Winoto, A.4
  • 16
    • 0032723235 scopus 로고    scopus 로고
    • Nur77 transcription activity correlates with its apoptotic function in vivo
    • DOI 10.1002/(SICI)1521-4141(199911)29:11<3722::AID-IMMU3722>3.0. CO;2-N
    • Kuang AA, Cado D, Winoto A. Nur77 transcription activity correlates with its apoptotic function in vivo. Eur J Immunol 1999;29:3722-3728 (Pubitemid 29527821)
    • (1999) European Journal of Immunology , vol.29 , Issue.11 , pp. 3722-3728
    • Kuang, A.A.1    Cado, D.2    Winoto, A.3
  • 17
    • 0033915552 scopus 로고    scopus 로고
    • Transcriptional induction of Nur77 by indomethacin that results in apoptosis of colon cancer cells
    • Kang HJ, Song MJ, Choung SY, Kim SJ, Le MO. Transcriptional induction of Nur77 by indomethacin that results in apoptosis of colon cancer cells. Biol Pharm Bull 2000;23:815-819
    • (2000) Biol Pharm Bull , vol.23 , pp. 815-819
    • Kang, H.J.1    Song, M.J.2    Choung, S.Y.3    Kim, S.J.4    Le, M.O.5
  • 19
    • 21644456253 scopus 로고    scopus 로고
    • Activation of Nur77 by selected 1,1-bis(3′-indolyl)-1-(p- substituted phenyl)methanes induces apoptosis through nuclear pathways
    • DOI 10.1074/jbc.M500107200
    • Chintharlapalli S, Burghardt R, Papineni S, Ramaiah S, Yoon K, Safe S. Activation of Nur77 by selected 1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways. J Biol Chem 2005;280:24903-24914 (Pubitemid 40934582)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.26 , pp. 24903-24914
    • Chintharlapalli, S.1    Burghardt, R.2    Papineni, S.3    Ramaiah, S.4    Yoon, K.5    Safe, S.6
  • 20
    • 1342306819 scopus 로고    scopus 로고
    • Conversion of Bcl-2 from Protector to Killer by Interaction with Nuclear Orphan Receptor Nur77/TR3
    • DOI 10.1016/S0092-8674(04)00162-X
    • Lin B, Kolluri SK, Lin F, et al. Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 2004;116:527-540 (Pubitemid 38264430)
    • (2004) Cell , vol.116 , Issue.4 , pp. 527-540
    • Lin, B.1    Kolluri, S.K.2    Lin, F.3    Liu, W.4    Han, Y.-H.5    Cao, X.6    Dawson, M.I.7    Reed, J.C.8    Zhang, X.-K.9
  • 22
    • 0342265117 scopus 로고    scopus 로고
    • Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells
    • Bras A, Albar JP, Leonardo E, de Buitrago GG, Martinez AC. Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells. Cell Death Differ 2000;7:262-271 (Pubitemid 30192975)
    • (2000) Cell Death and Differentiation , vol.7 , Issue.3 , pp. 262-271
    • Bras, A.1    Albar, J.P.2    Leonardo, E.3    Gonzalez De Buitrago, G.4    Martinez-A, C.5
  • 23
    • 30844460373 scopus 로고    scopus 로고
    • Inhibition of apoptosis by Nur77 through NF-κB activity modulation
    • DOI 10.1038/sj.cdd.4401737, PII 4401737
    • de Leseleuc L, Denis F. Inhibition of apoptosis by Nur77 through NF-κB activity modulation. Cell Death Differ 2006;13:293-300. (Pubitemid 43102212)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.2 , pp. 293-300
    • De Leseleuc, L.1    Denis, F.2
  • 25
    • 33646348742 scopus 로고    scopus 로고
    • 2 regulates the nuclear receptor NR4A2 in colorectal cancer
    • DOI 10.1074/jbc.M507752200
    • Holla VR, Mann JR, Shi Q, DuBois RN. Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer. J Biol Chem 2006;281:2676-2682 (Pubitemid 43845730)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.5 , pp. 2676-2682
    • Holla, V.R.1    Mann, J.R.2    Shi, Q.3    Dubois, R.N.4
  • 26
    • 0032740490 scopus 로고    scopus 로고
    • Stabilization and reactivation of the p53 tumor suppressor protein in nontumorigenic revertants of HeLa cervical cancer cells
    • Athanassiou M, Hu Y, Jing L, Houle B, Zarbl H, Mikheev AM. Stabilization and reactivation of the p53 tumor suppressor protein in nontumorigenic revertants of HeLa cervical cancer cells. Cell Growth Differ 1999;10:729-737
    • (1999) Cell Growth Differ , vol.10 , pp. 729-737
    • Athanassiou, M.1    Hu, Y.2    Jing, L.3    Houle, B.4    Zarbl, H.5    Mikheev, A.M.6
  • 27
    • 1642545618 scopus 로고    scopus 로고
    • A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation
    • DOI 10.1093/carcin/bgg190
    • Mikheev AM, Mikheeva SA, Liu B, Cohen P, Zarbl H. A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation. Carcinogenesis 2004;25:47-59. (Pubitemid 38128618)
    • (2004) Carcinogenesis , vol.25 , Issue.1 , pp. 47-59
    • Mikheev, A.M.1    Mikheeva, S.A.2    Liu, B.3    Cohen, P.4    Zarbl, H.5
  • 28
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995;80:293-299
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 29
    • 0035837241 scopus 로고    scopus 로고
    • The role of tetramerization in p53 function
    • Chene P. The role of tetramerization in p53 function. Oncogene 2001;20:2611-2617
    • (2001) Oncogene , vol.20 , pp. 2611-2617
    • Chene, P.1
  • 31
    • 0000190727 scopus 로고    scopus 로고
    • Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system
    • DOI 10.1016/0169-328X(96)00074-5
    • Zetterstrom RH, Williams R, Perlmann T, Olson L. Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system. Brain Res Mol Brain Res 1996;41:111-120 (Pubitemid 26288151)
    • (1996) Molecular Brain Research , vol.41 , Issue.1-2 , pp. 111-120
    • Zetterstrom, R.H.1    Williams, R.2    Perlmann, T.3    Olson, L.4
  • 33
    • 4344592679 scopus 로고    scopus 로고
    • Induction of orphan nuclear receptor Nur77 gene expression and its role in cadmium-induced apoptosis in lung
    • Shin HJ, Lee BH, Yeo MG, et al. Induction of orphan nuclear receptor Nur77 gene expression and its role in cadmium-induced apoptosis in lung. Carcinogenesis 2004;25:1467-1475
    • (2004) Carcinogenesis , vol.25 , pp. 1467-1475
    • Shin, H.J.1    Lee, B.H.2    Yeo, M.G.3
  • 35
    • 33846909753 scopus 로고    scopus 로고
    • Microarray analyses support a role for Nurr1 in resistance to oxidative stress and neuronal differentiation in neural stem cells
    • DOI 10.1634/stemcells.2006-0238
    • Sousa KM, Mira H, Hall AC, Jansson-Sjostrand L, Kusakabe M, Arenas E. Microarray analyses support a role for Nurr1 in resistance to oxidative stress and neuronal differentiation in neural stem cells. Stem Cells 2007;25:511-519 (Pubitemid 46232807)
    • (2007) Stem Cells , vol.25 , Issue.2 , pp. 511-519
    • Sousa, K.M.1    Mira, H.2    Hall, A.C.3    Jansson-Sjostrand, L.4    Kusakabe, M.5    Arenas, E.6
  • 36
    • 51449083112 scopus 로고    scopus 로고
    • SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria,as well as increases FOXO3a dependent gene expression
    • Jacobs KM, Pennington JD, Bisht KS, et al. SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria,as well as increases FOXO3a dependent gene expression. Int J Biol Sci 2008;4:291-299
    • (2008) Int J Biol Sci , vol.4 , pp. 291-299
    • Jacobs, K.M.1    Pennington, J.D.2    Bisht, K.S.3
  • 37
    • 55249085401 scopus 로고    scopus 로고
    • Yoon JH. cAMP-responding element-binding protein and c-Ets1 interact in the regulation of ATP-dependent MUC5AC gene expression
    • Song KS, Lee TJ, Kim K, Chung KC, Yoon JH. cAMP-responding element-binding protein and c-Ets1 interact in the regulation of ATP-dependent MUC5AC gene expression. J Biol Chem 2008;283:26869-26878
    • (2008) J Biol Chem , vol.283 , pp. 26869-26878
    • Song, K.S.1    Lee, T.J.2    Kim, K.3    Chung, K.C.4
  • 40
    • 34547830362 scopus 로고    scopus 로고
    • The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor
    • DOI 10.1093/nar/gkm476
    • Lee J, Beliakoff J, Sun Z. The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor. Nucleic Acids Res 2007;35:4523-4534 (Pubitemid 47244603)
    • (2007) Nucleic Acids Research , vol.35 , Issue.13 , pp. 4523-4534
    • Lee, J.1    Beliakoff, J.2    Sun, Z.3
  • 41
    • 15744381220 scopus 로고    scopus 로고
    • Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate
    • Hudson CD, Morris PJ, Latchman DS, Budhram-Mahadeo VS. Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate. J Biol Chem 2005;280:11851-11858
    • (2005) J Biol Chem , vol.280 , pp. 11851-11858
    • Hudson, C.D.1    Morris, P.J.2    Latchman, D.S.3    Budhram-Mahadeo, V.S.4
  • 42
    • 33845903036 scopus 로고    scopus 로고
    • Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression
    • DOI 10.1093/nar/gkl878
    • Budhram-Mahadeo VS, Bowen S, Lee S, et al. Brn-3b enhances the proapoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression. Nucleic Acids Res 2006;34:6640-6652 (Pubitemid 46017957)
    • (2006) Nucleic Acids Research , vol.34 , Issue.22 , pp. 6640-6652
    • Budhram-Mahadeo, V.S.1    Bowen, S.2    Lee, S.3    Perez-Sanchez, C.4    Ensor, E.5    Morris, P.J.6    Latchman, D.S.7
  • 44
    • 0030249597 scopus 로고    scopus 로고
    • Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity
    • Trimmer PA, Smith TS, Jung AB, Bennett JP, Jr. Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity. Neurodegeneration 1996;5:233-239
    • (1996) Neurodegeneration , vol.5 , pp. 233-239
    • Trimmer, P.A.1    Smith, T.S.2    Jung, A.B.3    Bennett Jr., J.P.4
  • 45
    • 40849138195 scopus 로고    scopus 로고
    • DJ-1 decreases Bax expression through repressing p53 transcriptional activity
    • Fan J, Ren H, Jia N, et al. DJ-1 decreases Bax expression through repressing p53 transcriptional activity. J Biol Chem 2008;283:4022-4030
    • (2008) J Biol Chem , vol.283 , pp. 4022-4030
    • Fan, J.1    Ren, H.2    Jia, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.