메뉴 건너뛰기




Volumn 34, Issue 22, 2006, Pages 6640-6652

Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN BAX; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BRN 3B PROTEIN; UNCLASSIFIED DRUG;

EID: 33845903036     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl878     Document Type: Article
Times cited : (31)

References (65)
  • 2
    • 0028344395 scopus 로고
    • Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes
    • Theil,T., Zechner,U., Klett,C., Adolph,S. and Moroy,T. (1994) Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes. Cytogenet. Cell Genet., 66, 267-271.
    • (1994) Cytogenet. Cell Genet. , vol.66 , pp. 267-271
    • Theil, T.1    Zechner, U.2    Klett, C.3    Adolph, S.4    Moroy, T.5
  • 3
  • 4
    • 0029764545 scopus 로고    scopus 로고
    • The functionally antagonistic POU family transcription factors Brn-3a and Brn-3b show opposite changes in expression during the growth arrest and differentiation of human neuroblastoma cells
    • Smith,M.D. and Latchman,D.S. (1996) The functionally antagonistic POU family transcription factors Brn-3a and Brn-3b show opposite changes in expression during the growth arrest and differentiation of human neuroblastoma cells. Int. J. Cancer, 67, 653-660.
    • (1996) Int. J. Cancer , vol.67 , pp. 653-660
    • Smith, M.D.1    Latchman, D.S.2
  • 5
    • 0028896677 scopus 로고
    • The levels of the antagonistic POU family transcription factors Brn-3a and Brn-3b in neuronal cells are regulated in opposite directions by serum growth factors
    • Budhram-Mahadeo,V., Lillycrop,K.A. and Latchman,D.S. (1995) The levels of the antagonistic POU family transcription factors Brn-3a and Brn-3b in neuronal cells are regulated in opposite directions by serum growth factors. Neurosci. Lett., 185, 48-51.
    • (1995) Neurosci. Lett. , vol.185 , pp. 48-51
    • Budhram-Mahadeo, V.1    Lillycrop, K.A.2    Latchman, D.S.3
  • 6
    • 0035899340 scopus 로고    scopus 로고
    • The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells
    • Dennis,J.H., Budhram-Mahadeo,V. and Latchman,D.S. (2001) The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells. Oncogene, 20, 4961-4971.
    • (2001) Oncogene , vol.20 , pp. 4961-4971
    • Dennis, J.H.1    Budhram-Mahadeo, V.2    Latchman, D.S.3
  • 7
    • 0033581874 scopus 로고    scopus 로고
    • The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells
    • Budhram-Mahadeo,V., Ndisang,D., Ward,T., Weber,B.L. and Latchman,D.S. (1999) The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells. Oncogene, 18, 6684-6691.
    • (1999) Oncogene , vol.18 , pp. 6684-6691
    • Budhram-Mahadeo, V.1    Ndisang, D.2    Ward, T.3    Weber, B.L.4    Latchman, D.S.5
  • 8
    • 2442706707 scopus 로고    scopus 로고
    • The Brn-3b transcription factor regulates the growth, behavior and invasiveness of human neuroblastoma cells in vitro and in vivo
    • Irshad,S., Pedley,R.B., Anderson,J., Latchman,D.S. and Budhram-Mahadeo,V. (2004) The Brn-3b transcription factor regulates the growth, behavior and invasiveness of human neuroblastoma cells in vitro and in vivo. J. Biol. Chem., 279, 21617-21627.
    • (2004) J. Biol. Chem. , vol.279 , pp. 21617-21627
    • Irshad, S.1    Pedley, R.B.2    Anderson, J.3    Latchman, D.S.4    Budhram-Mahadeo, V.5
  • 10
    • 0029863515 scopus 로고    scopus 로고
    • POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells
    • Gan,L., Xiang,M., Zhou,L., Wagner,D.S., Klein,W.H. and Nathans,J. (1996) POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells. Proc. Natl Acad. Sci. USA, 93, 3920-3925.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 3920-3925
    • Gan, L.1    Xiang, M.2    Zhou, L.3    Wagner, D.S.4    Klein, W.H.5    Nathans, J.6
  • 11
    • 0031012652 scopus 로고    scopus 로고
    • Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor
    • Smith,M.D., Dawson,S.J. and Latchman,D.S. (1997) Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor. J. Biol. Chem., 272, 1382-1388.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1382-1388
    • Smith, M.D.1    Dawson, S.J.2    Latchman, D.S.3
  • 13
    • 0029045854 scopus 로고
    • Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor
    • Lakin,N.D., Morris,P.J., Theil,T., Sato,T.N., Moroy,T., Wilson,M.C. and Latchman,D.S. (1995) Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor. J. Biol. Chem., 270, 15858-15863.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15858-15863
    • Lakin, N.D.1    Morris, P.J.2    Theil, T.3    Sato, T.N.4    Moroy, T.5    Wilson, M.C.6    Latchman, D.S.7
  • 16
    • 0031031287 scopus 로고    scopus 로고
    • The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins
    • Smith,M.D., Dawson,S.J. and Latchman,D.S. (1997) The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins. Mol. Cell Biol., 17, 345-354.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 345-354
    • Smith, M.D.1    Dawson, S.J.2    Latchman, D.S.3
  • 18
    • 16544373301 scopus 로고    scopus 로고
    • Activation of CDK4 Gene Expression in Human Breast Cancer Cells by the Brn-3b POU Family Transcription Factor
    • Samady,L., Dennis,J., Budhram-Mahadeo,V. and Latchman,D.S. (2004) Activation of CDK4 Gene Expression in Human Breast Cancer Cells by the Brn-3b POU Family Transcription Factor. Cancer Biol. Ther., 3, 317-323.
    • (2004) Cancer Biol. Ther. , vol.3 , pp. 317-323
    • Samady, L.1    Dennis, J.2    Budhram-Mahadeo, V.3    Latchman, D.S.4
  • 21
    • 0028950999 scopus 로고
    • Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression
    • Thompson,M.E., Jensen,R.A., Obermiller,P.S., Page,D.L. and Holt,J.T. (1995) Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nature Genet., 9, 444-450.
    • (1995) Nature Genet. , vol.9 , pp. 444-450
    • Thompson, M.E.1    Jensen, R.A.2    Obermiller, P.S.3    Page, D.L.4    Holt, J.T.5
  • 22
    • 0031906243 scopus 로고    scopus 로고
    • POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element
    • Budhram-Mahadeo,V., Parker,M. and Latchman,D.S. (1998) POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element. Mol. Cell Biol., 18, 1029-1041.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 1029-1041
    • Budhram-Mahadeo, V.1    Parker, M.2    Latchman, D.S.3
  • 23
    • 20244381126 scopus 로고    scopus 로고
    • Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in breast cancer biopsies and is required for maximal activation of the HSP-27 promoter
    • Lee,S.A., Ndisang,D., Patel,C., Dennis,J.H., Faulkes,D.J., D'Arrigo,C., Samady,L., Farooqui-Kabir,S., Heads,R.J., Latchman,D.S. et al. (2005) Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in breast cancer biopsies and is required for maximal activation of the HSP-27 promoter. Cancer Res, 65, 3072-3080.
    • (2005) Cancer Res , vol.65 , pp. 3072-3080
    • Lee, S.A.1    Ndisang, D.2    Patel, C.3    Dennis, J.H.4    Faulkes, D.J.5    D'Arrigo, C.6    Samady, L.7    Farooqui-Kabir, S.8    Heads, R.J.9    Latchman, D.S.10
  • 24
    • 0032212922 scopus 로고    scopus 로고
    • The Brn-3a transcription factor
    • Latchman,D.S. (1998) The Brn-3a transcription factor. Int. J. Biochem. Cell Biol., 30, 1153-1157.
    • (1998) Int. J. Biochem. Cell Biol. , vol.30 , pp. 1153-1157
    • Latchman, D.S.1
  • 25
    • 0033591217 scopus 로고    scopus 로고
    • p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor
    • Budhram-Mahadeo,V., Morris,P.J., Smith,M.D., Midgley,C.A., Boxer,L.M. and Latchman,D.S. (1999) p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor. J. Biol. Chem., 274, 15237-15244.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15237-15244
    • Budhram-Mahadeo, V.1    Morris, P.J.2    Smith, M.D.3    Midgley, C.A.4    Boxer, L.M.5    Latchman, D.S.6
  • 26
    • 10644277060 scopus 로고    scopus 로고
    • Coexpression of Brn-3a POU protein with p53 in a population of neuronal progenitor cells is associated with differentiation and protection against apoptosis
    • Hudson,C.D., Podesta,J., Henderson,D., Latchman,D.S. and Budhram-Mahadeo,V. (2004) Coexpression of Brn-3a POU protein with p53 in a population of neuronal progenitor cells is associated with differentiation and protection against apoptosis. J. Neurosci. Res., 78, 803-814.
    • (2004) J. Neurosci. Res. , vol.78 , pp. 803-814
    • Hudson, C.D.1    Podesta, J.2    Henderson, D.3    Latchman, D.S.4    Budhram-Mahadeo, V.5
  • 27
    • 0037112732 scopus 로고    scopus 로고
    • Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter
    • Perez-Sanchez,C., Budhram-Mahadeo,V.S. and Latchman,D.S. (2002) Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter. Nucleic Acids Res., 30, 4872-4880.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 4872-4880
    • Perez-Sanchez, C.1    Budhram-Mahadeo, V.S.2    Latchman, D.S.3
  • 29
    • 0033552641 scopus 로고    scopus 로고
    • The p53 gene family
    • Kaelin,W.G., Jr (1999) The p53 gene family. Oncogene, 18, 7701-7705.
    • (1999) Oncogene , vol.18 , pp. 7701-7705
    • Kaelin Jr., W.G.1
  • 30
    • 0031987277 scopus 로고    scopus 로고
    • Regulation of p53 downstream genes
    • El Deiry,W.S. (1998) Regulation of p53 downstream genes. Semin. Cancer Biol., 8, 345-357.
    • (1998) Semin. Cancer Biol. , vol.8 , pp. 345-357
    • El Deiry, W.S.1
  • 31
    • 0038075338 scopus 로고    scopus 로고
    • Decision making by p53: Life, death and cancer
    • Oren,M. (2003) Decision making by p53: Life, death and cancer. Cell Death Differ., 10, 431-442.
    • (2003) Cell Death Differ. , vol.10 , pp. 431-442
    • Oren, M.1
  • 35
    • 0035810054 scopus 로고    scopus 로고
    • Regulation of the G2/M transition by p53 3
    • Taylor,W.R. and Stark,G.R. (2001) Regulation of the G2/M transition by p53 3. Oncogene, 20, 1803-1815.
    • (2001) Oncogene , vol.20 , pp. 1803-1815
    • Taylor, W.R.1    Stark, G.R.2
  • 36
    • 15744381220 scopus 로고    scopus 로고
    • Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate
    • Hudson,C.D., Morris,P.J., Latchman,D.S. and Budhram-Mahadeo,V.S. (2005) Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate. J. Biol. Chem., 280, 11851-11858.
    • (2005) J. Biol. Chem. , vol.280 , pp. 11851-11858
    • Hudson, C.D.1    Morris, P.J.2    Latchman, D.S.3    Budhram-Mahadeo, V.S.4
  • 37
    • 0033757828 scopus 로고    scopus 로고
    • Development of sensory neurons in the absence of NGF/TrkA signaling in vivo 1
    • Patel,T.D., Jackman,A., Rice,F.L., Kucera,J. and Snider,W.D. (2000) Development of sensory neurons in the absence of NGF/TrkA signaling in vivo 1. Neuron, 25, 345-357.
    • (2000) Neuron , vol.25 , pp. 345-357
    • Patel, T.D.1    Jackman, A.2    Rice, F.L.3    Kucera, J.4    Snider, W.D.5
  • 38
    • 0032520195 scopus 로고    scopus 로고
    • Widespread elimination of naturally occurring neuronal death in Bax-deficient mice
    • White,F.A., Keller-Peck,C.R., Knudson,C.M., Korsmeyer,S.J. and Snider,W.D. (1998) Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J. Neurosci., 18, 1428-1439.
    • (1998) J. Neurosci. , vol.18 , pp. 1428-1439
    • White, F.A.1    Keller-Peck, C.R.2    Knudson, C.M.3    Korsmeyer, S.J.4    Snider, W.D.5
  • 39
    • 1642332256 scopus 로고    scopus 로고
    • Sensory neurons from mice lacking the Brn-3b POU family transcription factor are resistant to death-inducing stimuli both in vitro and in vivo
    • Ensor,E., Mathews,K., Payne,S. and Latchman,D.S. (2003) Sensory neurons from mice lacking the Brn-3b POU family transcription factor are resistant to death-inducing stimuli both in vitro and in vivo. Brain Res. Mol. Brain Res., 117, 206-212.
    • (2003) Brain Res. Mol. Brain Res. , vol.117 , pp. 206-212
    • Ensor, E.1    Mathews, K.2    Payne, S.3    Latchman, D.S.4
  • 40
    • 0035895956 scopus 로고    scopus 로고
    • The BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosis
    • Ensor,E., Smith,M.D. and Latchman,D.S. (2001) The BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosis. J. Biol. Chem., 276, 5204-5212.
    • (2001) J. Biol. Chem. , vol.276 , pp. 5204-5212
    • Ensor, E.1    Smith, M.D.2    Latchman, D.S.3
  • 41
    • 0032523801 scopus 로고    scopus 로고
    • Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors
    • Xiang,M. (1998) Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev.Biol., 197, 155-169.
    • (1998) Dev.Biol. , vol.197 , pp. 155-169
    • Xiang, M.1
  • 42
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • Vousden,K.H. and Lu,X. (2002) Live or let die: The cell's response to p53. Nature Rev. Cancer, 2, 594-604.
    • (2002) Nature Rev. Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 43
    • 0035156707 scopus 로고    scopus 로고
    • p53-dependent pathways of apoptosis
    • Benchimol,S. (2001) p53-dependent pathways of apoptosis. Cell Death Differ., 8, 1049-1051.
    • (2001) Cell Death Differ. , vol.8 , pp. 1049-1051
    • Benchimol, S.1
  • 44
    • 0034628848 scopus 로고    scopus 로고
    • Cell cycle. Piecing together the p53 puzzle
    • [comment]
    • Carr,A.M. (2000) Cell cycle. Piecing together the p53 puzzle [comment]. Science, 287, 1765-1766.
    • (2000) Science , vol.287 , pp. 1765-1766
    • Carr, A.M.1
  • 45
    • 0027938209 scopus 로고
    • Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age
    • Hunter,T. and Pines,J. (1994) Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell, 79, 573-582.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 46
    • 0029808591 scopus 로고    scopus 로고
    • Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons
    • McEvilly,R.J., Erkman,L., Luo,L., Sawchenko,P.E., Ryan,A.F. and Rosenfeld,M.G. (1996) Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature, 384, 574-577.
    • (1996) Nature , vol.384 , pp. 574-577
    • McEvilly, R.J.1    Erkman, L.2    Luo, L.3    Sawchenko, P.E.4    Ryan, A.F.5    Rosenfeld, M.G.6
  • 47
    • 0029964874 scopus 로고    scopus 로고
    • Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling
    • Xiang,M., Gan,L., Zhou,L., Klein,W.H. and Nathans,J. (1996) Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling. Proc. Natl Acad. Sci. USA, 93, 11950-11955.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 11950-11955
    • Xiang, M.1    Gan, L.2    Zhou, L.3    Klein, W.H.4    Nathans, J.5
  • 48
    • 0033564455 scopus 로고    scopus 로고
    • POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification
    • Gan,L., Wang,S.W., Huang,Z. and Klein,W.H. (1999) POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification. Dev. Biol., 210, 469-480.
    • (1999) Dev. Biol. , vol.210 , pp. 469-480
    • Gan, L.1    Wang, S.W.2    Huang, Z.3    Klein, W.H.4
  • 49
    • 0027221174 scopus 로고
    • Mutant p53 proteins have diverse intracellular abilities to oligomerize and activate transcription
    • Miller,C.W., Chumakov,A., Said,J., Chen,D.L., Aslo,A. and Koeffler,H.P. (1993) Mutant p53 proteins have diverse intracellular abilities to oligomerize and activate transcription. Oncogene, 8, 1815-1824.
    • (1993) Oncogene , vol.8 , pp. 1815-1824
    • Miller, C.W.1    Chumakov, A.2    Said, J.3    Chen, D.L.4    Aslo, A.5    Koeffler, H.P.6
  • 51
    • 0029767029 scopus 로고    scopus 로고
    • p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells
    • Eizenberg,O., Faber-Elman,A., Gottlieb,E., Oren,M., Rotter,V. and Schwartz,M. (1996) p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells. Mol. Cell Biol., 16, 5178-5185.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 5178-5185
    • Eizenberg, O.1    Faber-Elman, A.2    Gottlieb, E.3    Oren, M.4    Rotter, V.5    Schwartz, M.6
  • 52
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko,L.J. and Prives,C. (1996) p53: Puzzle and paradigm. Genes Dev., 10, 1054-1072.
    • (1996) Genes Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 54
    • 0030898680 scopus 로고    scopus 로고
    • Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice
    • Shindler,K.S., Latham,C.B. and Roth,K.A. (1997) Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice. J. Neurosci., 17, 3112-3119.
    • (1997) J. Neurosci. , vol.17 , pp. 3112-3119
    • Shindler, K.S.1    Latham, C.B.2    Roth, K.A.3
  • 55
    • 33645160453 scopus 로고    scopus 로고
    • Distinct susceptibility of developing neurons to death following Bax overexpression in the chicken embryo 1
    • Sato,N., Sakuma,C., Sato,Y., Gould,T.W., Oppenheim,R.W. and Yaginuma,H. (2006) Distinct susceptibility of developing neurons to death following Bax overexpression in the chicken embryo 1. Cell Death Differ., 13, 435-445.
    • (2006) Cell Death Differ. , vol.13 , pp. 435-445
    • Sato, N.1    Sakuma, C.2    Sato, Y.3    Gould, T.W.4    Oppenheim, R.W.5    Yaginuma, H.6
  • 57
    • 31544453355 scopus 로고    scopus 로고
    • The Brn-3b POU family transcription factor represses plakoglobin gene expression in human breast cancer cells
    • Samady,L., Faulkes,D.J., Budhram-Mahadeo,V., Ndisang,D., Potter,E., Brabant,G. and Latchman,D.S. (2005) The Brn-3b POU family transcription factor represses plakoglobin gene expression in human breast cancer cells. Int. J. Cancer, 187 (4), 869-878.
    • (2005) Int. J. Cancer , vol.187 , Issue.4 , pp. 869-878
    • Samady, L.1    Faulkes, D.J.2    Budhram-Mahadeo, V.3    Ndisang, D.4    Potter, E.5    Brabant, G.6    Latchman, D.S.7
  • 58
    • 1942517848 scopus 로고    scopus 로고
    • Myc: A weapon of mass destruction
    • Secombe,J., Pierce,S.B. and Eisenman,R.N. (2004) Myc: A weapon of mass destruction. Cell, 117, 153-156.
    • (2004) Cell , vol.117 , pp. 153-156
    • Secombe, J.1    Pierce, S.B.2    Eisenman, R.N.3
  • 59
    • 0028171968 scopus 로고
    • Mediation of c-Myc-induced apoptosis by p53
    • Hermeking,H. and Eick,D. (1994) Mediation of c-Myc-induced apoptosis by p53. Science, 265, 2091-2093.
    • (1994) Science , vol.265 , pp. 2091-2093
    • Hermeking, H.1    Eick, D.2
  • 63
    • 0028082927 scopus 로고
    • Cell cycle arrest and morphological differentiation can occur in the absence of apoptosis in a neuronal cell line
    • Budhram-Mahadeo,V., Lillycrop,K.A. and Latchman,D.S. (1994) Cell cycle arrest and morphological differentiation can occur in the absence of apoptosis in a neuronal cell line. Neurosci. Lett., 165, 18-22.
    • (1994) Neurosci. Lett. , vol.165 , pp. 18-22
    • Budhram-Mahadeo, V.1    Lillycrop, K.A.2    Latchman, D.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.