Brain tumor development in rats is associated with changes in central nervous system cytokine and neuropeptide systems

Brain Research Bulletin

Volumn 48, Issue 4, 1999, Pages 363-373

  Ilyin, Sergey E ^a   Gayle, Dave ^a   González Gómez, Ignacio ^b   Miele, Mary E ^a   Plata Salamán, Carlos R ^a,c  

^a UNIVERSITY OF DELAWARE   (United States)

^b CHILDREN S HOSPITAL LOS ANGELES   (United States)

^c R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

Feeding; Growth factor; Hypothalamus; Interleukin; Tumor necrosis factor

Indexed keywords

CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; LEPTIN RECEPTOR; MESSENGER RNA; NEUROPEPTIDE; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; PROTEIN S 100; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; VIMENTIN;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN REGION; BRAIN TUMOR; CEREBELLUM; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEEDING BEHAVIOR; FOOD INTAKE; FRONTAL CORTEX; GENE EXPRESSION REGULATION; GLIOMA CELL; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR MODEL; NONHUMAN; PARIETAL LOBE; PRIORITY JOURNAL; RAT; RNA ANALYSIS; RNA TRANSCRIPTION;

ANIMALS; BRAIN NEOPLASMS; CENTRAL NERVOUS SYSTEM; CYTOKINES; GLIOMA; IMMUNOHISTOCHEMISTRY; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; MALE; NEUROPEPTIDES; RATS; RATS, WISTAR; RECEPTORS, INTERLEUKIN-1; RNA, MESSENGER; SIALOGLYCOPROTEINS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033103215     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(99)00005-2     Document Type: Article

References (50)

1. Baumann, H.; Morella, K. K.; White, D. W.; Dembski, M.; Bailon, P. S.; Kim, H.; Lai, C.-F.; Tartaglia, L. A. The full length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. Proc. Natl. Acad. Sci. USA 93:8374-8378; 1996.
2. Bernstein, J. J.; Woodard, C. A. Glioblastoma cells do not intravasate into blood vessels. Neurosurgery 36:124-132; 1995.
3. Bissonnette, E. Y.; Enciso, J. A.; Befus, A. D. TGF-β1 inhibits the release of histamine and tumor necrosis factor-α from mast cells through an autocrine pathway. Am. J. Respir. Cell. Mol. Biol. 16:275-282; 1997.
4. Chance, W. T.; Balasubramaniam, A.; Dayal, R.; Brown, J.; Fischer, J. E. Hypothalamic concentration and release of neuropeptide Y into microdialysates is reduced in anorectic tumor-bearing rats. Life Sci. 54:1869-1874; 1994.
5. Cremona, S.; Goujon, E.; Kelley, K. W.; Dantzer, R.; Parnet, P. Brain type I but not type II IL-1 receptors mediate the effects of IL-1β on behavior in mice. Am. J. Physiol. 274:R735-R740; 1998.
6. da Cunha, A.; Jefferson, J. J.; Tyor, W. R.; Glass, J. D.; Jannotta, F. S.; Cottrell, J. R.; Resau, J. H. Transforming growth factor-β1 in adult human microglia and its stimulated production by interleukin-1. J. Interf. Cytokine Res. 17:655-664; 1997.
7. Di Meco, F.; Benedetti, S.; Colombo, M. P.; Finocchiaro, G. Perspectives for the gene therapy of malignant gliomas by suicide gene transfer. J. Neurosurg. Sci. 41:227-234; 1997.
8. Dinarello, C. A. Biological basis for interleukin-1 in disease. Blood 87:2095-2147; 1996.
9. Fang, J. D.; Wang, Y.; Krueger, J. M. Effects of interleukin-1β on sleep are mediated by the type I receptor. Am. J. Physiol. 274:R655-R660; 1998.
10. Flynn, M. C.; Scott, T. R.; Pritchard, T. C.; Plata-Salamán, C. R. Mode of action of OB protein (leptin) on feeding. Am. J. Physiol. 275:R174-R179; 1998.
11. Gayle, D.; Ilyin, S. E.; Flynn, M. C.; Plata-Salamán, C. R. Lipopoly-saccharide (LPS)- and muramyl dipeptide (MDP)-induced anorexia during refeeding following acute fasting: Characterization of brain cytokine and neuropeptide systems mRNAs. Brain Res. 795:77-86; 1998.
12. Gayle, D.; Ilyin, S. E.; Plata-Salamán, C. R. Central nervous system IL-1β system and neuropeptide Y mRNAs during IL-1β-induced anorexia in rats. Brain Res. Bull. 44:311-317; 1997.
13. Gillespie, G. Y. Cytokines as modulators of malignant glioma progression. In: Ransohoff, R. M.; Benveniste, E. N., eds. Cytokines and the CNS. Boca Raton: CRC Press; 1996: 269-286.
14. Greenfeder, S. A.; Nunes, P.; Kwee, L.; Labow, M.; Chizzonite, R. A.; Ju, G. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270:13757-13765; 1995.
15. Herrlinger, U.; Buchholz, R.; Jachimczak, P.; Schabet, M. Intrathecal treatment of C6 glioma leptomeningeal metastasis in Wistar rats with interleukin-2. J. Neurooncol. 27:193-203; 1996.
16. Ilyin, S. E.; González-Gómez, I.; Gilles, F. H.; Plata-Salamán, C. R. Interleukin-1α (IL-lα), IL-1β, IL-1 receptor type I, IL-1 receptor antagonist and TGF-β1 mRNAs in pediatric astrocytomas, ependymomas and primitive neuroectodermal tumors. Mol. Chem. Neuropathol. 33:125-137; 1998.
17. Ilyin, S. E.; Gayle, D.; Flynn, M. C.; Plata-Salamán, C. R. Interleukin-1β system (ligand, receptor type I, receptor accessory protein and receptor antagonist), TNF-α, TGF-β1 and neuropeptide Y mRNAs in specific brain regions during bacterial LPS-induced anorexia. Brain Res. Bull. 45:507-515; 1998.
18. Ilyin, S. E.; Plata-Salamán, C. R. HIV-1 gp120 modulates hypothalamic cytokine mRNAs in vivo: Implications to cytokine feedback systems. Biochem. Biophys. Res. Commun. 231:514-518; 1997.
19. Izquierdo, M.; Cortes, M.; de Felipe, P.; Martin, V.; Diaz-Guerra, J.; Talavera, A.; Perez-Higueras, A. Long-term rat survival after malignant brain tumor regression by retroviral gene therapy. Gene Ther. 2:66-69; 1995.
20. Jevric-Causevic, A.; Diksic, M. The rate of valine incorporation into proteins with correction for valine recycling, measured in two brain tumor models and the cortex. J. Neurochem. 66:1574-1581; 1996.
21. Kitamura, I.; Kochi, M.; Matsumoto, Y.; Ueoka, R.; Kuratsu, J.; Ushio, Y. Intrathecal chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea encapsulated into hybrid liposomes for meningeal gliomatosis: An experimental study. Cancer Res. 56:3986-3992; 1996.
22. Liu, C.; Chalmers, D.; Maki, R.; De Souza, E. B. Rat homolog of mouse interleukin-1 receptor accessory protein: Cloning, localization and modulation studies. J. Neuroimmunol. 66:41-48; 1996.
23. Maron, A.; Gustin, T.; Le Roux, A.; Mottet, I.; Dedieu, J. F.; Brion, J. P.; Demeure, R.; Perricaudet, M.; Octave, J. N. Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: Long-term follow-up by magnetic resonance imaging. Gene Ther. 3:315-322; 1996.
24. Menei, P.; Boisdron-Celle, M.; Croue, A.; Guy, G.; Benoit, J. P. Effect of stereotactic implantation of biodegradable 5-fluorouracil-loaded microspheres in healthy and C6 glioma-bearing rats. Neurosurgery 39:117-123; 1996.
25. Mokry, J.; Nemecek, S.; Adler, J.; Dedic, K. Inoculation of C6 cell suspension into the brain of adult rats: Immunohistochemical study. Funct. Dev. Morphol. 3:175-180; 1993.
26. Morreale, V. M.; Herman, B. H.; Der Minassian, V.; Palkovits, M.; Klubes, P.; Perry, D.; Csiffary, A.; Lee, A. P. A brain-tumor model utilizing stereotactic implantation of a permanent cannula. J. Neurosurg. 78:959-965; 1993.
27. Nagano, N.; Sasaki, H.; Aoyagi, M.; Hirakawa, K. Invasion of experimental rat brain tumor: early morphological changes following microinjection of C6 glioma cells. Acta Neuropathol. (Berl.) 86:117-125; 1993.
28. Nieto-Sampedro, M.; Bailon, C.; Fernandez-Mayoralas, A.; Martin-Lomas, M.; Mellstrom, B.; Naranjo, J. R. Experimental brain glioma: Growth arrest and destruction by a blood-group-related tetrasaccharide. J. Neuropathol. Exp. Neurol. 55:169-177; 1996.
29. Ohshiro, S.; Inagawa, H.; Soma, G.; Fukushima, T.; Tomonaga, M. Antitumor effect of exogenous/endogenous TNF (EET) therapy with cyclophosphamide on C6 glioma in rat. Cancer Biother. 9:359-367; 1994.
30. Plata-Salamán, C. R. Anorexia induced by activators of the signal transducer gp 130. NeuroReport 7:841-844; 1996.
31. Plata-Salamán, C. R. Anorexia during acute and chronic disease. Nutrition 12:69-78; 1996.
32. Plata-Salamán, C. R.; Ilyin, S. E. IL-1β-induced modulation of the hypothalamic IL-1β system, TNF-α and TGF-β1 mRNAs in obese (fa/fa) and lean (Fa/Fa) Zucker rats: Implications to IL-1β feedback systems and cytokine-cytokine interactions. J. Neurosci. Res. 49:541-550; 1997.
33. Plata-Salamán, C. R.; Ilyin, S. E.; Gayle, D. Brain cytokine mRNAs in anorectic rats bearing prostate adenocarcinoma tumor cells. Am. J. Physiol. 275:R566-R573; 1998.
34. Plata-Salamán, C. R.; Ilyin, S. E.; Gayle, D.; Flynn, M. C. Gram-negative and Gram-positive bacterial products induce differential cytokine profiles in the brain: Analysis using an integrative molecular-behavioral in vivo Model. Int. J. Mol. Med. 1:387-397; 1998.
35. Plata-Salamán, C. R.; Sonti, G.; Borkoski, J. P.; Wilson, C. D.; ffrench-Mullen, J. M. H. Anorexia induced by chronic central administration of cytokines at estimated pathophysiological concentrations. Physiol. Behav. 60:867-875; 1996.
36. Politis, M. J.; Lindsay, J. K. Exogenous interleukin regulates growth of C6 tumors in vivo. Acta Neuropathol. (Berl.) 77:182-185; 1988.
37. Renner, U.; Pagotto, U.; Arzt, E.; Stalla, G. K. Autocrine and paracrine roles of polypeptide growth factors, cytokines and vasogenic substances in normal and tumorous pituitary function and growth: A review. Eur. J. Endocrinol. 135:515-532; 1996.
38. Sahu, A.; White, J. D.; Kalra, P. S.; Kalra, S. P. Hypothalamic neuropeptide Y gene expression in rats on scheduled feeding regimen. Mol. Brain Res. 15:15-18; 1992.
39. San-Galli, F.; Vrignaud, P.; Robert, J.; Coindre, J. M.; Cohadon, F. Assessment of the experimental model of transplanted C6 glioblastoma in Wistar rats. J. Neurooncol. 7:299-304; 1989.
40. Sims, J. E.; Gayle, M. A.; Slack, J. L.; Alderson, M. R.; Bird, T. A.; Giri, J. G.; Colotta, F.; Re, F.; Mantovani, A.; Shanebeck, K.; Grabstein, K. H.; Dower, S. D. Interleukin-1 signalling occurs exclusively via the type 1 receptor. Proc. Natl. Acad. Sci. USA 90:6155-6159; 1993.
41. Sonti, G.; Ilyin, S. E.; Plata-Salamán, C. R. Anorexia induced by cytokine interactions at pathophysiological concentrations. Am. J. Physiol. 270: R1394-R 1402; 1996.
42. Sonti, G.; Ilyin, S. E.; Plata-Salamán, C. R. Neuropeptide Y blocks and reverses interleukin-1β-induced anorexia in rats. Peptides 17:517-520; 1996.
43. Sonti, G.; Flynn, M. C.; Plata-Salamán, C. R. Interleukin-1 (IL-1) receptor type I mediates anorexia, but not adipsia induced by centrally administered IL-1β. Physiol. Behav. 62:1179-1183; 1997.
44. Taga, T.; Kishimoto, T. gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15:797-819; 1997.
45. Takeda, N.; Diksic, M.; Yamamoto, Y. L. The sequential changes in DNA synthesis, glucose utilization, protein synthesis, and peripheral benzodiazepine receptor density in C6 brain tumors after chemotherapy to predict the response of tumors to chemotherapy. Cancer 77:1167-1179; 1996.
46. Tamaki, M.; Aoyagi, M.; Morita, I.; Hirakawa, K.; Murota, S. Cell adhesion molecules acting between C6 glioma and endothelial cells. J. Neurooncol. 24:181-188; 1995.
47. Tseng, S. H.; Hwang, L. H.; Lin, S. M. Induction of antitumor immunity by intracerebrally implanted rat C6 glioma cells genetically engineered to secrete cytokines. J. Immunother. 20:334-342; 1997.
48. Whittle, I. R.; Marston, H. M. Progressive focal neurological dysfunction following experimental implantation glioma. Neuroreport 8:1149-1153; 1997.
49. Winkler, M. K.; Benveniste, E. N. Transforming growth factor-β inhibition of cytokine-induced vascular cell adhesion molecule-1 expression in human astrocytes. Glia 22:171-179; 1998.
50. Yoshida, T.; Shimizu, K.; Ushio, Y.; Hayakawa, T.; Arita, N.; Mogami, H. Development of experimental meningeal gliomatosis models in rats. J. Neurosurg. 65:503-507; 1986.