Modeling the G-protein-coupled neuropeptide Y Y1 receptor agonist and antagonist binding sites

Protein Engineering

Volumn 10, Issue 2, 1997, Pages 109-117

  Du, Ping ^a   Salon, John A ^a   Tamm, Joseph A ^a   Hou, Cuifen ^a,c   Cui, Weili ^a   Walker, Mary W ^a   Adham, Nika ^a   Dhanoa, Daljit S ^a,d   Islam, Imadul ^a,e   Vaysse, Pierre J J ^a   Dowling, Barbara ^a   Shifman, Yelena ^a   Boyle, Noel ^a   Rueger, Heinrich ^b   Schmidlin, Tibur ^b   Yamaguchi, Yashuchika ^b   Branchek, Theresa A ^a   Weinshank, Richard L ^a   Gluchowski, Charles ^a  

^a H LUNDBECK A S   (Denmark)

^b CIBA GEIGY LTD   (Switzerland)

^c JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^d Alanex Corporation   (United States)

^e BAYER AG   (Germany)

Author keywords

Agonist; Antagonist; Model; Mutagenesis; Neuropeptide

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROXYL GROUP; MUTANT PROTEIN; NALPHA (DIPHENYLACETYL) N (4 HYDROXYBENZYL) DEXTRO ARGININAMIDE; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR AGONIST; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y1 RECEPTOR; RECEPTOR SUBTYPE;

ARTICLE; BINDING SITE; COMPUTER MODEL; HYDROGEN BOND; MOLECULAR MODEL; MUTAGENESIS; PRIORITY JOURNAL; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

EID: 0031042157     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/10.2.109     Document Type: Article

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