Artificial β-defensin based on a minimal defensin template

Biochemical Journal

Volumn 421, Issue 3, 2009, Pages 435-447

  Antcheva, Nikolinka ^a   Morgera, Francesca ^a   Creatti, Luisa ^a   Vaccari, Lisa ^b   Pag, Ulrike ^c   Pacor, Sabrina ^a   Shai, Yechiel ^d   Sahl, Hans Georg ^c   Tossi, Alessandro ^a   Sha, Hans Georg ^c   Shai, Hans Georgy ^c  

^a UNIVERSITY OF TRIESTE   (Italy)

^b SINCROTRONE TRIESTE   (Italy)

^c UNIVERSITY OF BONN   (Germany)

^d WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

defensin; Antimicrobial peptide; Chemotaxis; Host defence peptide; Innate immunity

Indexed keywords

ANTI-MICROBIAL ACTIVITY; ANTIMICROBIAL PEPTIDE; BIOLOGICAL ACTIVITIES; CHEMOTACTIC ACTIVITY; CHEMOTAXIS; COMPARATIVE ANALYSIS; CORE STRUCTURE; DEFENSINS; DENDRITIC CELLS; DIFFERENT MODES; DISULFIDE BRIDGE; HOST CELLS; HOST DEFENCE PEPTIDE; INNATE IMMUNITY; MODE OF ACTION; NATURALLY OCCURRING; ORTHOLOGUES; SALT-SENSITIVE; STRUCTURAL FEATURE; STRUCTURE ACTIVITY RELATIONSHIPS;

BIOCHEMISTRY; DENDRIMERS; PEPTIDES;

AMINES;

BETA DEFENSIN; CYSTEINE; SERINE;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BETA SHEET; BINDING AFFINITY; BURKHOLDERIA CEPACIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DENDRITIC CELL; DIMERIZATION; DRUG POTENCY; ESCHERICHIA COLI; HOST CELL; HUMAN; IMMUNOMODULATION; MALE; MINIMUM INHIBITORY CONCENTRATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SEQUENCE ALIGNMENT; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; ANIMAL; BACTERIUM; CHEMISTRY; DRUG EFFECT; IMMUNOLOGY; INNATE IMMUNITY; MICROBIOLOGICAL EXAMINATION; MOLECULAR GENETICS; PRIMATE; SYNTHESIS;

PRIMATES;

AMINO ACID SEQUENCE; ANIMALS; BACTERIA; BETA-DEFENSINS; DIMERIZATION; HUMANS; IMMUNITY, INNATE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PRIMATES; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 69249244285     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20082242     Document Type: Article

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