Dynasore inhibits removal of wild-type and ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) from the plasma membrane

Biochemical Journal

Volumn 421, Issue 3, 2009, Pages 377-385

  Young, Andrew ^a   Gentzsch, Martina ^b   Abban, Cynthia Y ^a   Jia, Ying ^a   Meneses, Patricio I ^a   Bridges, Robert J ^a   Bradbury, Neil A ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Cystic fibrosis transmembrane conductance regulator (CFTR); Dynamin; Dynasore; Endocytosis; Small interfering RNA (siRNA)

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR); DYNAMIN; DYNASORE; ENDOCYTOSIS; SMALL INTERFERING RNA (SIRNA);

BIOCHEMISTRY; BIOSYNTHESIS; NUCLEIC ACIDS; RNA;

CELL MEMBRANES;

CORR 4; DYNAMIN; DYNASORE; FORSKOLIN; MUTANT PROTEIN; PROTEIN INHIBITOR; SMALL INTERFERING RNA; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG; HYDRAZONE DERIVATIVE; N' (3,4 DIHYDROXYBENZYLIDENE) 3 HYDROXY 2 NAPHTHAHYDRAZIDE; N'-(3,4-DIHYDROXYBENZYLIDENE)-3-HYDROXY-2-NAPHTHAHYDRAZIDE;

ARTICLE; CELL MEMBRANE; COATED PIT; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG TARGETING; ENDOCYTOSIS; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; PROTEIN EXPRESSION; THERMOSTABILITY; WILD TYPE; DOWN REGULATION; DRUG EFFECT; GENETICS; HELA CELL; METABOLISM; PROTEIN TRANSPORT;

CELL MEMBRANE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DOWN-REGULATION; ENDOCYTOSIS; HELA CELLS; HUMANS; HYDRAZONES; PROTEIN TRANSPORT;

EID: 69249227507     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090389     Document Type: Article

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