HPV16 and BPV1 infection can be blocked by the dynamin inhibitor dynasore

American Journal of Therapeutics

Volumn 15, Issue 4, 2008, Pages 304-311

  Abban, Cynthia Y ^a   Bradbury, Neil A ^a,b   Meneses, Patricio I ^a,b  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

Dynamin inhibitor; Dynamin mediated endocytosis; Dynasore; Papillomavirus antiviral; Papillomavirus endocytosis; Viral infection

Indexed keywords

ANTIVIRUS AGENT; DYNAMIN; DYNASORE; GUANOSINE TRIPHOSPHATASE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; HYDRAZONE DERIVATIVE;

ARTICLE; BOVINE PAPILLOMAVIRUS TYPE 1; CELL STRAIN HEK293; CONCENTRATION RESPONSE; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME INHIBITION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; PRIORITY JOURNAL; VIRUS ENTRY; CELL LINE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG DELIVERY SYSTEM; DRUG EFFECT; PATHOGENICITY; TIME;

ANTIVIRAL AGENTS; BOVINE PAPILLOMAVIRUS 1; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; DYNAMINS; GTP PHOSPHOHYDROLASES; HUMAN PAPILLOMAVIRUS 16; HUMANS; HYDRAZONES; TIME FACTORS;

EID: 51649111041     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/MJT.0b013e3181754134     Document Type: Article

References (24)

1. Ehrlich M, Boll W, Van Oijen A, et al. Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell. 2004;118:591-605.
2. Gaidarov I, Santini F, Warren RA, et al. Spatial control of coated-pit dynamics in living cells. Nat Cell Biol. 1999;1:1-7.
3. Mayor S, Pagano RE. Pathways of clathrin-independent endocytosis. Nat Rev Mol Cell Biol. 2007;8:603-612.
4. Pelkmans L, Helenius A. Insider information: what viruses tell us about endocytosis. Curr Opin Cell Biol. 2003;15:414-422.
5. van der Goot FG, Gruenberg J. Intra-endosomal membrane traffic. Trends Cell Biol. 2006;16:514-521.
6. Lajoie P, Nabi IR. Regulation of raft-dependent endocytosis. J Cell Mol Med. 2007;11:644-653.
7. Ungewickell EJ, Hinrichsen L. Endocytosis: clathrin-mediated membrane budding. Curr Opin Cell Biol. 2007; 19:417-425.
8. Liu J, Kaksonen M, Drubin DG, et al. Endocytic vesicle scission by lipid phase boundary forces. Proc Natl Acad Sci USA. 2006;103:10277-10282.
9. Roux A, Cuvelier D, Nassoy P, et al. Role of curvature and phase transition in lipid sorting and fission of membrane tubules. Embo J. 2005;24:1537-1545.
10. Roux A, Uyhazi K, Frost A, et al. GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission. Nature. 2006;441528-531.
11. Damke H, Baba T, Warnock DE, et al. Induction of mutant dynamin specifically blocks endocytic coated vesicle formation. J Cell Biol. 1994;127:915-934.
12. Muro S, Wiewrodt R, Thomas A, et al. A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1. J Cell Sci. 2003;116:1599-1609.
13. Schlunck G, Damke H, Kiosses WB, et al. Modulation of Rac localization and function by dynamin. Mol Biol Cell. 2004;15:256-267.
14. Macia E, Ehrlich M, Massol R, et al. Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell. 2006;10:839-850.
15. Newton AJ, Kirchhausen T, Murthy VN. Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis. Proc Natl Acad Sci USA 2006;103: 17955-17960.
16. Campo MS. Animal models of papillomavirus pathogenesis. Virus Res. 2002;89:249-261.
17. Howley P, Lowy P. Papillomavirus and their replication. Fundam Virol. 2001;4:1019-1052.
18. Meneses P, Robertson E. Papillomavirus biology and therapeutic approaches. Gene Ther Mol Biol. 2005; 9: 217-228.
19. Day PM, Lowy DR, Schiller JT. Papillomaviruses infect cells via a clathrin-dependent pathway. Virology. 2003; 307:1-11.
20. Hindmarsh PL, Laimins LA. Mechanisms regulating expression of the HPV 31 L1 and L2 capsid proteins and pseudovirion entry. Virol J. 2007;4:19.
21. Smith JL, Campos SK, Ozbun MA. Human papillomavirus type 31 uses a caveolin 1-and dynamin 2-mediated entry pathway for infection of human keratinocytes. J Virol 2007;81:9922-9931.
22. Merrifield C J, Feldman ME, Wan L, et al. Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits. Nat Cell Biol. 2002;4:691-698.
23. Pelkmans L, Helenius A. Endocytosis via caveolae. Traffic. 2002; 3:311-320.
24. Buck GB, Pastrana DV, Lowy DR, et al. Efficient intracellular assembly of papillomaviral vectors. J Virol. 2004;78:751-757.