Mapping the dynamics of ligand reorganization via 13CH3 and 13CH2 relaxation dispersion at natural abundance

Journal of Biomolecular NMR

Volumn 45, Issue 1-2, 2009, Pages 171-183

  Peng, Jeffrey W ^a   Wilson, Brian D ^a   Namanja, Andrew T ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

Drug design; Dynamics; Ligand; Relaxation dispersion; Side chain

Indexed keywords

CARBON 13; METHYL GROUP; NEW DRUG; PEPTIDYLPROLYL ISOMERASE PIN1; PROTEIN TYROSINE PHOSPHATASE;

ARTICLE; CATALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISPERSION; DRUG CONFORMATION; DRUG DESIGN; DRUG RESEARCH; DRUG STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; BINDING SITES; CARBON ISOTOPES; HUMANS; LIGANDS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDYLPROLYL ISOMERASE; PHOSPHOPEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS;

EID: 69249208408     PISSN: 09252738     EISSN: 15735001     Source Type: Journal    
DOI: 10.1007/s10858-009-9349-4     Document Type: Article

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