Leptin and ObRa/MEK signalling in mouse oocyte maturation and preimplantation embryo development

Reproductive BioMedicine Online

Volumn 19, Issue 2, 2009, Pages 181-190

  Ye, Yinghui ^a,c   Kawamura, Kazuhiro ^a   Sasaki, Mitsue ^a   Kawamura, Nanami ^a,b   Groenen, Peter ^d   Sollewijn Gelpke, Maarten D ^d   Kumagai, Jin ^a   Fukuda, Jun ^a   Tanaka, Toshinobu ^a  

^a Department of Obstetrics and Gynecology ^*  (China)

^b AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d NV ORGANON   (Netherlands)

Author keywords

Leptin; Leptin receptor; Oocyte maturation; Signal transduction

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CHORIONIC GONADOTROPIN; LEPTIN; LEPTIN RECEPTOR; LEPTIN RECEPTOR A; LEPTIN RECEPTOR B; LUTEINIZING HORMONE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CUMULUS CELL; EMBRYO; EMBRYO DEVELOPMENT; FERTILIZATION IN VITRO; GERMINAL VESICLE; GRANULOSA CELL; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OOCYTE MATURATION; OVARY FOLLICLE; PARACRINE SIGNALING; PREIMPLANTATION EMBRYO; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; THECA CELL; TISSUE DISTRIBUTION;

EID: 69249093090     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-6483(10)60070-3     Document Type: Article

References (58)

1. Abir R, Ao A, Jin S et al. 2005 Leptin and its receptors in human fetal and adult ovaries. Fertility and Sterility 84, 1779-1782. (Pubitemid 41785690)
2. Antczak M, Van Blerkom J 1997 Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. Molecular Human Reproduction 3, 1067-1086. (Pubitemid 127509913)
3. Archanco M, Muruzabal FJ, Llopiz D et al. 2003 Leptin expression in the rat ovary depends on estrous cycle. Journal of Histochemistry and Cytochemistry 51, 1269-1277. (Pubitemid 37187578)
4. Asimakopoulos B, Abu-Hassan D, Metzen E et al. 2008 The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection. Fertility and Sterility 90, 60-64. (Pubitemid 351885179)
5. Asimakopoulos B, Nikolettos N, Papachristou DN et al. 2005 Follicular fluid levels of vascular endothelial growth factor and leptin are associated with pregnancy outcome of normal women participating in intracytoplasmic sperm injection cycles. Physiological Research 54, 263-270. (Pubitemid 40956768)
6. Barroso G, Barrionuevo M, Rao P et al. 1999 Vascular endothelial growth factor, nitric oxide, and leptin follicular fluid levels correlate negatively with embryo quality in IVF patients. Fertility and Sterility 72, 1024-1026.
7. Boelhauve M, Sinowatz F, Wolf E, Paula-Lopes FF 2005 Maturation of bovine oocytes in the presence of leptin improves development and reduces apoptosis of in vitro-produced blastocysts. Biology of Reproduction 73, 737-744. (Pubitemid 41356133)
8. Borsuk E, Milik E 2005 Fully grown mouse oocyte contains transcription inhibiting activity which acts through histone deacetylation. Molecular Reproduction and Development 71, 509-515. (Pubitemid 40923518)
9. Bouniol-Baly C, Hamraoui L, Guibert J et al. 1999 Differential transcriptional activity associated with chromatin configuration in fully grown mouse germinal vesicle oocytes. Biology of Reproduction 60, 580-587. (Pubitemid 29102386)
10. Brannian JD, Schmidt SM, Kreger D, O'Hansen KA 2001 Baseline non-fasting serum leptin concentration to body mass index ratio is predictive of IVF outcomes. Human Reproduction 16, 1819-1826. (Pubitemid 32916206)
11. Cervero A, Horcajadas JA, Dominguez F et al. 2005 Leptin system in embryo development and implantation: a protein in search of a function. Reproductive BioMedicine Online 10, 217-223. (Pubitemid 40246637)
12. Cioffi JA, Van Blerkom J, Antczak M et al. 1997 The expression of leptin and its receptors in pre-ovulatory human follicles. Molecular Human Reproduction 3, 467-472. (Pubitemid 127509365)
13. Craig J, Zhu H, Dyce PW et al. 2004 Leptin enhances oocyte nuclear and cytoplasmic maturation via the mitogen-activated protein kinase pathway. Endocrinology 145, 5355-5363. (Pubitemid 39551157)
14. De Placido G, Alviggi C, Clarizia R et al. 2006 Intra-follicular leptin concentration as a predictive factor for in vitro oocyte fertilization in assisted reproductive techniques. Journal of Endocrinological Investigation 29, 719-726. (Pubitemid 44756177)
15. Dorn C, Reinsberg J, Kupka M et al. 2003 Leptin, VEGF, IGF-1, and IGFBP-3 concentrations in serum and follicular fluid of women undergoing in vitro fertilization. Archives of Gynecology and Obstetrics 268, 187-193. (Pubitemid 36988455)
16. Eppig JJ 1996 Coordination of nuclear and cytoplasmic oocyte maturation in eutherian mammals. Reproduction, Fertility, and Development 8, 485-489.
17. Fan H-Y, Sun Q-Y 2004 Involvement of mitogen-activated protein kinase cascade during oocyte maturation and fertilization in mammals. Biology of Reproduction 70, 535-547. (Pubitemid 38233690)
18. Fan H-Y, Huo L-J, Chen D-Y et al. 2004 Protein kinase C and mitogen-activated protein kinase cascade in mouse cumulus cells: cross talk and effect on meiotic resumption of oocyte. Biology of Reproduction 70, 1178-1187.
19. Fruhbeck G 2006 Intracellular signalling pathways activated by leptin. Biochemical Journal 393, 7-20. (Pubitemid 43049298)
20. Fulka J, First NL, Moor RM 1998 Nuclear and cytoplasmic determinants involved in the regulation of mammalian oocyte maturation. Molecular Human Reproduction 4, 41-49. (Pubitemid 28109159)
21. Goumenou AG, Matalliotakis IM, Koumantakis GE, Panidis DK 2003 The role of leptin in fertility. European Journal of Obstetrics and Gynecology and Reproductive Biology 106, 118-124.
22. Hamm ML, Bhat GK, Thompson WE, Mann DR 2004 Folliculogenesis is impaired and granulosa cell apoptosis is increased in leptin-deficient mice. Biology of Reproduction 71, 66-72.
23. Han DC, Isono M, Chen S et al. 2001 Leptin stimulates type I collagen production in db/db mesangial cells: glucose uptake and TGF-beta type II receptor expression. Kidney International 59, 1315-1323. (Pubitemid 32281219)
24. Hegyi K, Fulop K, Kovacs K et al. 2004 Leptin-induced signal transduction pathways. Cell Biology International 28, 159-169.
25. Hill MJ, Uyehara CF, Hashiro GM, Frattarelli JL 2007 The utility of serum leptin and follicular fluid leptin, estradiol, and progesterone levels during an in vitro fertilization cycle. Journal of Assisted Reproduction and Genetics 24, 183-188.
26. Hosoi T, Okuma Y, Nomura Y 2002 Leptin regulates interleukin-1 beta expression in the brain via the STAT3-independent mechanisms. Brain Research 949, 139-146. (Pubitemid 35246186)
27. Ihle JN 1995 Cytokine receptor signalling. Nature 377, 591-594.
28. Kawamura K, Kawamura N, Mulders SM el al. 2005 Ovarian brain-derived neurotrophic factor (BDNF) promotes the development of oocytes into preimplantation embryos. Proceedings of the National Academy of Sciences of the USA 102, 9206-9211.
29. Kawamura K, Kumagai J, Sudo S et al. 2004 Paracrine regulation of mammalian oocyte maturation and male germ cell survival. Proceedings of the National Academy of Sciences of the USA 101, 7323-7328. (Pubitemid 38638031)
30. Kawamura K, Sato N, Fukuda J et al. 2002 Leptin promotes the development of mouse preimplantation embryos in vitro. Endocrinology 143, 1922-1931. (Pubitemid 34415908)
31. Konstantinides S, Schafer K, Neels JG et al. 2004 Inhibition of endogenous leptin protects mice from arterial and venous thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology 24, 2196-2201. (Pubitemid 39482452)
32. Kun Z, Shaohua W, Yufang M et al. 2007 Effects of leptin supplementation in in vitro maturation medium on meiotic maturation of oocytes and preimplantation development of parthenogenetic and cloned embryos in pigs. Animal Reproduction Science 101, 85-96. (Pubitemid 46964835)
33. LaRosa C, Downs SM 2005 MEK inhibitors block AICAR-induced maturation in mouse oocytes by a MAPK-independent mechanism. Molecular Reproduction and Development 70, 235-245.
34. Li MG, Ding GL, Chen XJ et al. 2007 Association of senim and follicular fluid leptin concentrations with granulosa cell phosphorylated signal transducer and activator of transcription 3 expression in fertile patients with polycystic ovarian syndrome. Journal of Clinical Endocrinology and Metabolism 92, 4771-4776.
35. Lo K-M, Zhang J, Sun Y et al. 2005 Engineering a pharmacologically superior form of leptin for the treatment of obesity. Protein Engineering, Design and Selection 18, 1-10. (Pubitemid 40516986)
36. Loffler S, Aust G, Kohler U, Spanel-Borowski K 2001 Evidence of leptin expression in normal and polycystic human ovaries. Molecular Human Reproduction 7, 1143-1149. (Pubitemid 33150209)
37. Mantzoros CS, Cramer DW, Liberman RF, Barbieri RL 2000 Predictive value of serum and follicular fluid leptin concentrations during assisted reproductive cycles in normal women and in women with the polycystic ovarian syndrome. Human Reproduction 15, 539-544.
38. Marin Bivens CL, Grondahl C, Murray A et al. 2004 Meiosis-activating sterol promotes the metaphase I to metaphase II transition and preimplantation developmental competence of mouse oocytes maturing in vitro. Biology of Reproduction 70, 1458-1464. (Pubitemid 38509694)
39. Matsuoka T, Tahara M, Yokoi T et al. 1999 Tyrosine phosphorylation of STAT3 by leptin through leptin receptor in mouse metaphase 2 stage oocyte. Biochemical and Biophysical Research Communications 256, 480-484. (Pubitemid 29301131)
40. Myers MG 2004 Leptin receptor signaling and the regulation of mammalian physiology. Recent Progress in Hormone Research 59, 287-304.
41. Nakano H, Kubo H 2001 Rescue of mouse embryos from 2-cell blocks by microinjection of maturation promoting factor. Fertility and Sterility 75, 1194-1197. (Pubitemid 32522619)
42. Nebreda AR, Ferby I 2000 Regulation of the meiotic cell cycle in oocytes. Current Opinion in Cell Biology 12, 666-675. (Pubitemid 30947600)
43. Nikolettos N, Asimakopoulos B, Nicolettos N et al. 2004 Evaluation of leptin, interleukin-1 beta, tumor necrosis factor-alpha and vascular endothelial growth factor in serum and follicular fluids of women undergoing controlled ovarian hyperstimulation as prognostic markers of ICSI outcome. In Vivo 18, 667-673. (Pubitemid 39409646)
44. Park J-Y, Su Y-Q, Ariga M et al. 2004 EGF-like growth factors as mediators of LH action in the ovulatory follicle. Science 303, 682-684. (Pubitemid 38141636)
45. Paula-Lopes FF, Boelhauve M, Habermann FA et al. 2007 Leptin promotes meiotic progression and developmental capacity of bovine oocytes via cumulus cell-independent and -dependent mechanisms. Biology of Reproduction 76, 532-541. (Pubitemid 46311040)
46. Peng XR, Hsueh AJ, LaPolt PS et al. 1991 Localization of luteinizing hormone receptor messenger ribonucleic acid expression in ovarian cell types during follicle development and ovulation. Endocrinology 129, 3200-3207.
47. Ryan NK, Van der Hoek KH, Robertson SA, Norman RJ 2003 Leptin and leptin receptor expression in the rat ovary. Endocrinology 144, 5006-5013. (Pubitemid 37378416)
48. Ryan NK, Woodhouse CM, Van der Hoek KH et al. 2002 Expression of leptin and its receptor in the murine ovary: possible role in the regulation of oocyte maturation. Biology of Reproduction 66, 1548-1554.
49. Sahai A, Malladi P, Pan X et al. 2004 Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. American Journal of Physiology Gastrointestinal and Liver Physiology 287, G1035-G1043. (Pubitemid 39423696)
50. Swain JE, Dunn RL, McConnell D et al. 2004 Direct effects of leptin on mouse reproductive function: regulation of follicular, oocyte, and embryo development. Biology of Reproduction 71, 1446-1452. (Pubitemid 39403237)
51. Sweeney G 2002 Leptin signalling. Cellular Signalling 14, 655-663.
52. Tanghe S, Van Soom A, Nauwynck H et al. 2002 Minireview: functions of the cumulus oophorus during oocyte maturation, ovulation, and fertilization. Molecular Reproduction and Development 61, 414-424. (Pubitemid 34117059)
53. Truchet S, Chebrout M, Djediat C et al. 2004 Presence of permanently activated signal transducers and activators of transcription in nuclear interchromatin granules of unstimulated mouse oocytes and preimplantation embryos. Biology of Reproduction 71, 1330-1339. (Pubitemid 39249820)
54. Tsafriri A, Chun SY, Zhang R et al. 1996 Oocyte maturation involves compartmentalization and opposing changes of cAMP levels in follicular somatic and germ cells: studies using selective phosphodiesterase inhibitors. Developmental Biology 178, 393-402. (Pubitemid 26365046)
55. Tsai EM, Yang CH, Chen SC et al. 2002 Leptin affects pregnancy outcome of in vitro fertilization and steroidogenesis of human granulosa cells. Journal of Assisted Reproduction and Genetics 19, 169-176.
56. Welt CK, Schneyer AL, Heist K, Mantzoros CS 2003 Leptin and soluble leptin receptor in follicular fluid. Journal of Assisted Reproduction and Genetics 20, 495-501. (Pubitemid 38294922)
57. Wunder DM, Kretschmer R, Bersinger NA 2005 Concentrations of leptin and C-reactive protein in serum and follicular fluid during assisted reproductive cycles. Human Reproduction 20, 1266-1271. (Pubitemid 40790251)
58. Yokoo M, Sato E 2004 Cumulus-oocyte complex interactions during oocyte maturation. International Review of Cytology 235, 251-291. (Pubitemid 38879432)