Leptin and Soluble Leptin Receptor in Follicular Fluid

Journal of Assisted Reproduction and Genetics

Volumn 20, Issue 12, 2003, Pages 495-501

  Welt, Corrine K ^a   Schneyer, Alan L ^a   Heist, Kathleen ^b   Mantzoros, Christos S ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Activin; Estradiol; Follistatin; Leptin; Oocyte

Indexed keywords

ACTIVIN A; ANDROSTENEDIONE; ESTRADIOL; INHIBIN A; INHIBIN B; LEPTIN; LEPTIN RECEPTOR; PROGESTERONE;

ADULT; ANDROSTENEDIONE BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; ESTRADIOL BLOOD LEVEL; FEMALE; FERTILIZATION IN VITRO; HUMAN; INFERTILITY; OOCYTE MATURATION; OVARY FOLLICLE; OVARY FOLLICLE FLUID; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; RADIOIMMUNOASSAY;

BODY MASS INDEX; BODY WEIGHT; FEMALE; FOLLICULAR FLUID; HUMANS; LEPTIN; RECEPTORS, CELL SURFACE; REPRODUCTIVE TECHNIQUES, ASSISTED;

FALLOPIA;

EID: 1542318275     PISSN: 10580468     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JARG.0000013649.38415.2a     Document Type: Article

References (34)

1. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S, Kern PA, Friedman JM: Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995;1:1155-1161
2. Sinha MK, Opentanova I, Ohannesian JP, Kolaczynski JW, Helman ML, Hale J, Becker GW, Bowsher RR, Stephens TW, Caro JF: Evidence of free and bound leptin in human circulation: Studies in lean and obese subjects and during short-term fasting. J Clin Invest 1996;98:1277-1282
3. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 1995;269:540-543
4. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM: Weight-reducing effects of the plasma protein encoded by the obese gene. Science 1995;269:543-546
5. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 1995;269:546-549
6. Tartaglia LA: The leptin receptor. J Biol Chem 1997;272:6093-6096
7. Lee G, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM: Abnormal splicing of the leptin receptor in diabetic mice. Nature 1996;379:632-635
8. Lammert A, Kiess W, Bottner A, Glasow A, Kratsch J: Soluble leptin receptor represents the main leptin binding activity in human blood. Biochem Biophys Res Commun 2001;283:982-988
9. Liu C, Liu X, Barry G, Ling N, Maki RA, DeSouza EB: Expression and characterization of a putative high affinity human soluble leptin receptor. Endocrinology 1997;138:3548-3554
10. Huang L, Wang Z, Li C: Modulation of circulating leptin levels by its soluble receptor. J Biol Chem 2001;276:6343-6349
11. Karlsson C, Lindell K, Svensson E, Bergh C, Lind P, Billig H, Carlsson LMS, Carlsson B: Expression of functional leptin receptors in the human ovary. J Clin Endocrinol Metab 1997;82:4144-4148
12. Cioffi JA, Van Blerkom J, Antczak M, Shafer A, Wittmer S, Snodgrass HR: The expression of leptin and its receptors in pre-ovulatory human follicles. Mol Hum Reprod 1997;3:467-472
13. Agarwal SK, Vogel K, Weitsman SR, Magoffin DA: Leptin antagonizes the insulin-like growth factor-I augmentation of steroidogenesis in granulosa and theca cells of the human ovary. J Clin Endocrinol Metab 1999;84:1072-1076
14. Brannian JD, Zhao Y, McElroy M: Leptin inhibits gonadotrophin-stimulated granulosa cell progesterone production by antagonizing insulin action. Hum Reprod 1999;14:1445-1448
15. Mantzoros CS, Cramer DW, Liberman RF, Barbieri RL: Predictive value of serum and follicular fluid leptin concentrations during assisted reproductive cycles in normal women and in women with polycystic ovarian syndrome. Hum Reproc 2000;15:539-544
16. Butzow TL, Moilanen JM, Lehtovirta M, Tuomi T, Hovatta O, Siegberg R, Nilsson C, Apter D: Serum and follicular fluid leptin during in vitro fertilization: Relationship among leptin increase, body fat mass, and reduced ovarian response. J Clin Endocrinol Metab 1999;84:3135-3139
17. Brannian JD, Schmidt SM, Kreger DO, Hansen KA: Baseline non-fasting serum leptin concentration to body mass index ratio is predictive of IVF outcome. Hum Reprod 2001;16:1819-1826
18. Fedorcsak P, Storeng R, Dale PO, Tanbo T, Torjesen P, Urbancsek J, Abyholm T: Leptin and leptin binding activity in the preovulatory follicle of polycystic ovary syndrome patients. Scand J Clin Lab Invest 2000;60:649-655
19. Kado N, Kitawaki J, Koshiba H, Ishihara H, Kitaoka Y, Teramoto M, Honjo HJ: Relationships between the serum levels of soluble leptin receptor and free and bound leptin in non-pregnant women of reproductive age and women undergoing controlled ovarian hyperstimulation. Hum Reprod 2003;18:715-720
20. Veeck L: Oocyte assessment and biological performance. Ann NY Acad Sci 1988;541:259-274
21. Lambert-Messerlian G, Taylor A, Leykin L, Isaacson K, Toth T, Chang Y, Schneyer A: Characterization of intrafollicular steroid hormones, inhibin, and follistatin in women with and without polycystic ovarian syndrome following gonadotropin hyperstimulation. Biol Reprod 1997;57:1211-1216
22. Fujiwara T, Lambert-Messerlian G, Sidis Y, Leykin L, Isaacson K, Toth T, Schneyer A: Analysis of follicular fluid hormone concentrations and granulosa cell mRNA levels for the inhibin-activin-follistatin system: Relationship to oocyte and embryo characteristics. Fertil Steril 2002;74:348-355
23. McConnell D, Wang QF, Sluss PM, Bolf N, Khoury RH, Schneyer AL, Midgley AR Jr, Reame NE, Crowley WF Jr, Padmanabhan V: A two site chimiluminescent assay for activin-free follistatin reveals that most follistatin circulating in men and normal cycling women is in an activin-bound state. J Clin Endocrinol Metab 2002;83:851-858
24. Chan JL, Bluher S, Yiannakouris N, Suchard MA, Kratzsch J, Mantzoros CS: Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: Observational and interventional studies in humans. Diabetes 2002;51:2105-2112
25. Lavoie HB, Taylor AE, Sharpless JL, Anderson EJ, Strauss CC, Hall JE: Effects of short-term hormone replacement on serum leptin levels in postmenopausal women. Clin Endocrinol (Oxf) 1999;51:415-422
26. Yoneda N, Saito S, Kimura M, Yamada M, Iida M, Murakami T, Irahara M, Shima K, Aono T: The influence of ovariectomy on ob gene expression in rats. Horm Metab Res 1998;30:263-265
27. Shimizu H, Shimomura Y, Nakanishi Y, Futawatari T, Ohtani K, Sato N, Mori M: Estrogen increases in vivo leptin production in rats and human subjects. J Endocrinol 1997;154:285-292
28. Machinal-Quelin F, Dieudonne MN, Pecquery R, Leneveu MC, Giudicelli Y: Direct in vitro effects of androgens and estrogens on ob gene expression and leptin secretion in human adipose tissue. Endocrine 2002;18:179-184
29. Casabiell X, Pineiro V, Peino R, Lage M, Camina J, Gallego R, Vallejo LG, Dieguez C, Casanueva FF: Gender differences in both spontaneous and stimulated leptin secretion by human omental adipose tissue in vitro: Dexamethasone and estradiol stimulate leptin release in women, but not in men. J Clin Endocrinol Metab 1998;83:2149-2155
30. Messinis IE, Kariotis I, Milingos S, Kollios J, Seferiadis K: Treatment of normal women with oestradiol plus progesterone prevents the decrease of leptin concentrations induced by ovariectomy. Hum Reprod 2000;15:2383-2387
31. Messinis IE, Papageoriou I, Milingos S, Asprodini E, Kollios J, Seferiadis K: Oestradiol plus progesterone treatment increases serum leptin concentrations in normal women. Hum Reprod 2001;16:1827-1832
32. Findlay JK: An update on the roles of inhibin, activin and follistatin as local regulators of folliculogenesis. Biol Reprod 1993;48:15-23
33. Hall JE, Welt CK, Cramer DW: Inhibin A and inhibin B reflect ovarian function in assisted reproduction but are less useful at predicting outcome. Hum Reprod 1998;14:409-415
34. Franchimont P, Hazee-Hagelstein MT, Charlet-Renard C, Jaspar JM, Hazout A, Salat-Baroux J, Schatz B, Demerle F: Correlation between follicualr fluid content and the results of in vitro fertilization and embryo transfer. II: Inhibin and aromatase inhibitor activity. J Clin Endocrinol Metab 1990;71:748-754