Expression of leptin and its receptor in the murine ovary: Possible role in the regulation of oocyte maturation

Biology of Reproduction

Volumn 66, Issue 5, 2002, Pages 1548-1554

  Ryan, Natalie K ^a   Woodhouse, Carole M ^a   Van der Hoek, Kylie H ^a   Gilchrist, Robert B ^a   Armstrong, David T ^a   Norman, Robert J ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Cytokines; Leptin; Leptin receptor; Oocyte development

Indexed keywords

CYTOKINE; LEPTIN; LEPTIN RECEPTOR; PHOSPHODIESTERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CUMULUS OOPHORUS; FEMALE; GERMINAL VESICLE; IMMUNOHISTOCHEMISTRY; MEIOSIS; MOUSE; NONHUMAN; OOCYTE DEVELOPMENT; OOCYTE MATURATION; OVARY; OVARY FOLLICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; THECA CELL;

ANIMALIA; MURINAE;

EID: 0036240470     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod66.5.1548     Document Type: Article

References (32)

1. Positional cloning of the mouse obese gene and its human homologue
2. Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats
3. Human obese gene expression: Adipocyte-specific expression and regional differences in the adipose tissue
4. Overexpression of the obese (ob) gene in adipose tissue of human obese subjects
5. Increased obese mRNA expression in omental fat cells from massively obese humans
6. Identification and expression cloning of a leptin receptor, OB-R
7. The expression of leptin and its receptors in pre-ovulatory human follicles
8. Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction
9. Expression of functional leptin receptors in the human ovary
10. Obese and diabetes: Two mutant genes causing diabetesobesity syndromes in mice
11. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
12. Leptin antagonizes the insulin-like growth factor-I augmentation of steroidogenesis in granulosa and theca cells of the human ovary
13. Leptin inhibits gonadotrophinstimulated granulosa cell progesterone production by antagonizing insulin action
14. Adipose obese gene product, leptin, inhibits bovine ovarian thecal cell steroidogenesis
15. The adipose obese gene product, leptin: Evidence of a direct inhibitory role in ovarian function
16. Direct intraovarian effects of leptin: Impairment of the synergistic action of insulin-like growth factor-I on follicle-stimulating hormone-dependent estradiol-17 beta production by rat ovarian granulosa cells
17. The in vivo and in vitro effects of exogenous leptin on ovulation in the rat
18. Effect of fasting and refeeding on plasma and follicular fluid leptin levels in prepubertal gilts
19. Tyrosine phosphorylation of STAT3 by leptin through leptin receptor in mouse metaphase 2 stage oocyte
20. Leptin inhibits insulin secretion by activation of phosphodiesterase 3B
21. Leptin induces insulin-like signaling that antagonizes cAMP elevation by glucagon in hepatocytes
22. Oocyte maturation involves compartmentalization and opposing changes of cAMP levels in follicular somatic and germ cells: Studies using selective phosphodiesterase inhibitors
23. Regulation of mouse oocyte meiotic maturation: Implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis
24. Lack of ovarian responsiveness to gonadotropic hormones in infantile rats sterilized with busulfan
25. Standardization of the chloramine-T method of protein iodination
26. The hypothalamic-pituitary axis in genetically obese (ob/ob) mice: Response to luteinizing hormone-releasing hormone
27. Oocyte influences on early development: The regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo
28. Effects of follicular cells on oocyte maturation. I: Effects of follicular hemisections on bovine oocyte maturation in vitro
29. Concentration of cyclic AMP during the maturation of pig oocytes in vivo and in vitro
30. Meiosis activating sterols (MAS) and fertility in mammals and man
31. Leptin signalling in pancreatic islets and clonal insulin-secreting cells
32. PD 98059 prevents establishment of the spindle assembly checkpoint and inhibits the G2-M transition in meiotic but not mitotic cell cycles in Xenopus