Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 31, 2009, Pages 12765-12770

  Naylor, Maria L ^a   Li, Ju Mei ^a   Osborn, Alex J ^b   Elledge, Stephen J ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Checkpoint; DNA damage; Replication stress response; S phase

Indexed keywords

CHEA KINASE; CHECKPOINT KINASE 2; DNA; MEC1 SENSOR KINASE; MEDIATOR OF REPLICATION CHECKPOINT 1; REPLISOME; UNCLASSIFIED DRUG; CDC45 PROTEIN, S CEREVISIAE; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; MEC1 PROTEIN, S CEREVISIAE; MRC1 PROTEIN, S CEREVISIAE; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; RAD53 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE S PHASE; CELL VIABILITY; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME STABILITY; FLUORESCENCE ACTIVATED CELL SORTING; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; YEAST; CHEMISTRY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

SACCHAROMYCETALES;

CELL CYCLE PROTEINS; DNA REPLICATION; DNA-BINDING PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; S PHASE; SACCHAROMYCES CEREVISIAE PROTEINS; STRESS, PHYSIOLOGICAL;

EID: 69149108736     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904623106     Document Type: Article

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