2′-Epi-2′-O-acetylthevetin B induces apoptosis partly via Ca2+-mediated mitochondrial pathway in human hepatocellular carcinoma HepG2 cells

Cell Biology International

Volumn 33, Issue 9, 2009, Pages 918-925

  Feng, Bo ^a   Huang, Cai Guo ^a   Chen, Ruo Hua ^c   Guo, Yue Wei ^b   Jiao, Bing Hua ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

2 Epi 2 O acetylthevetin B(GHSC 74); Apoptosis; Bcl 2; Ca2+; HepG2; Mitochondrial membrane potential ( m)

Indexed keywords

2' EPI 2' O ACETYLTHEVETIN B; CALCIUM CHELATING AGENT; CALCIUM ION; CARDIAC GLYCOSIDE; EGTAZIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GHSC 74; HOE 33342; LIPOCORTIN 5; PROTEIN BCL 2; UNCLASSIFIED DRUG; 1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER; 1,2-BIS(2-AMINOPHENOXY)ETHANE N,N,N',N'-TETRAACETIC ACID ACETOXYMETHYL ESTER; 2'-EPI-2'-O-ACETYLTHEVETIN B; ANTINEOPLASTIC AGENT; CALCIUM; CHELATING AGENT; DRUG DERIVATIVE; ENZYME INHIBITOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING ASSAY; CALCIUM CELL LEVEL; CELL DEATH; CELL STIMULATION; CELL STRAIN 3T3; CELL STRAIN HEPG2; CELL VIABILITY; CERBERA MANGHAS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; FIBROBLAST; HUMAN; HUMAN CELL; ISOLATION PROCEDURE; LIVER CELL; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PLANT; PLANT SEED; STAINING; ANIMAL; APOCYNACEAE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MITOCHONDRION; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CERBERA MANGHAS;

3T3 CELLS; ANIMALS; ANTICARCINOGENIC AGENTS; APOCYNACEAE; APOPTOSIS; CALCIUM; CARDIAC GLYCOSIDES; CELL LINE, TUMOR; CHELATING AGENTS; EGTAZIC ACID; ENZYME INHIBITORS; FIBROBLASTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 68949197993     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2009.06.013     Document Type: Article

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