-
1
-
-
43949133356
-
The genetics of essential metal homeostasis during development
-
Kambe, T., Weaver, B. P. and Andrews, G. K. (2008) The genetics of essential metal homeostasis during development. Genesis, 46, 214-228.
-
(2008)
Genesis
, vol.46
, pp. 214-228
-
-
Kambe, T.1
Weaver, B.P.2
Andrews, G.K.3
-
2
-
-
0035713724
-
The "metal transcription factor" MTF-1: Biological facts and medical implications
-
Lichtlen, P. and Schaffner, W. (2001) The "metal transcription factor" MTF-1: biological facts and medical implications. Swiss Med Wkly, 131, 647-652. (Pubitemid 34150440)
-
(2001)
Swiss Medical Weekly
, vol.131
, Issue.45-46
, pp. 647-652
-
-
Lichtlen, P.1
Schaffner, W.2
-
3
-
-
34047217992
-
Mechanism of metallothionein gene activation mediated by heavy-metal dependent transcription factor MTF-1
-
DOI 10.1248/yakushi.127.675
-
Otsuka, F., Ohno, S., Suzuki, K., Takahashi, K., Ohsawa, M. and Koizumi, S. (2007) Mechanism of metallothionein gene activation mediated by heavymetal dependent transcription factor MTF-1. Yakugaku Zasshi, 127, 675-684. (Pubitemid 46536540)
-
(2007)
Yakugaku Zasshi
, vol.127
, Issue.4
, pp. 675-684
-
-
Otsuka, F.1
Ohno, S.2
Suzuki, K.3
Takahashi, K.4
Ohsawa, M.5
Koizumi, S.6
-
4
-
-
34447105299
-
Understanding the mechanisms of zinc-sensing by metal-response element binding transcription factor-1 (MTF-1)
-
Laity, J. H. and Andrews, G. K. (2007) Understanding the mechanisms of zinc-sensing by metal-response element binding transcription factor-1 (MTF-1). Arch. Biochem. Biophys., 463, 201-210.
-
(2007)
Arch. Biochem. Biophys.
, vol.463
, pp. 201-210
-
-
Laity, J.H.1
Andrews, G.K.2
-
5
-
-
0028358324
-
The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression
-
Heuchel, R., Radtke, F., Georgiev, O., Stark, G., Aguet, M. and Schaffner, W. (1994) The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression. EMBO J., 13, 2870-2875. (Pubitemid 24191697)
-
(1994)
EMBO Journal
, vol.13
, Issue.12
, pp. 2870-2875
-
-
Heuchel, R.1
Radtke, F.2
Georgiev, O.3
Stark, G.4
Aguet, M.5
Schaffner, W.6
-
6
-
-
0029985755
-
Transgenic mice that overexpress metallothionein-I resist dietary zinc deficiency
-
Dalton, T., Fu, K., Palmiter, R. D. and Andrews G. K. (1996) Transgenic mice that overexpress metallothionein-I resist dietary zinc deficiency. J. Nutr., 126, 825-833.
-
(1996)
J. Nutr.
, vol.126
, pp. 825-833
-
-
Dalton, T.1
Fu, K.2
Palmiter, R.D.3
Andrews, G.K.4
-
7
-
-
0029987684
-
Metallothionein I and II protect against zinc deficiency and zinc toxicity in mice
-
Kelly, E. J., Quaife, C. J., Froelick, G. J. and Palmiter, R. D. (1996) Metallothionein I and II protect against zinc deficiency and zinc toxicity in mice. J. Nutr., 126, 1782-1790.
-
(1996)
J. Nutr.
, vol.126
, pp. 1782-1790
-
-
Kelly, E.J.1
Quaife, C.J.2
Froelick, G.J.3
Palmiter, R.D.4
-
8
-
-
0027955113
-
Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium
-
Masters, B. A., Kelly, E. J., Quaife, C. J., Brinster, R. L. and Palmiter, R. D. (1994) Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proc. Natl. Acad. Sci. U.S.A., 91, 584-588.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 584-588
-
-
Masters, B.A.1
Kelly, E.J.2
Quaife, C.J.3
Brinster, R.L.4
Palmiter, R.D.5
-
10
-
-
0031903927
-
Metallothionein transgenic and knock-out mouse models in the study of cadmium toxicity
-
Klaassen, C. D. and Liu, J. (1998) Metallothionein transgenic and knock-out mouse models in the study of cadmium toxicity. J. Toxicol. Sci., 23(Suppl 2), 97-102. (Pubitemid 28385008)
-
(1998)
Journal of Toxicological Sciences
, vol.23
, Issue.SUPPL. 2
, pp. 97-102
-
-
Klaassen, C.D.1
Liu, J.2
-
11
-
-
0034602175
-
The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene
-
Langmade, S. J., Ravindra, R., Daniels, P. J. and Andrews, G. K. (2000) The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene. J. Biol. Chem., 275, 34803-34809. (Pubitemid 30819261)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.44
, pp. 34803-34809
-
-
Langmade, S.J.1
Ravindra, R.2
Daniels, P.J.3
Andrews, G.K.4
-
12
-
-
0021986710
-
Building ametal-responsive promoter with synthetic regulatory elements
-
Searle, P. F., Stuart, G.W. and Palmiter, R. D. (1985) Building ametal-responsive promoter with synthetic regulatory elements. Mol. Cell. Biol., 5, 1480-1489.
-
(1985)
Mol. Cell. Biol.
, vol.5
, pp. 1480-1489
-
-
Searle, P.F.1
Stuart, G.W.2
Palmiter, R.D.3
-
13
-
-
0022410464
-
Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences
-
Stuart, G.W., Searle, P. F. and Palmiter, R. D. (1985) Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences. Nature, 317, 828-831.
-
(1985)
Nature
, vol.317
, pp. 828-831
-
-
Stuart, G.W.1
Searle, P.F.2
Palmiter, R.D.3
-
14
-
-
0024550092
-
Fine mapping of a mouse metallothionein gene metal response element
-
Culotta, V. C. and Hamer, D. H. (1989) Fine mapping of a mouse metallothionein gene metal response element. Mol. Cell. Biol., 9, 1376-1380.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 1376-1380
-
-
Culotta, V.C.1
Hamer, D.H.2
-
15
-
-
0033083839
-
Transcriptional activity and regulatory protein binding of metal- Responsive elements of the human metallothionein-IIA gene
-
DOI 10.1046/j.1432-1327.1999.00069.x
-
Koizumi, S., Suzuki, K., Ogra, Y., Yamada, H. and Otsuka, F. (1999) Transcriptional activity and regulatory protein binding of metal-responsive elements of the human metallothionein-IIA gene. Eur. J. Biochem., 259, 635-642. (Pubitemid 29075489)
-
(1999)
European Journal of Biochemistry
, vol.259
, Issue.3
, pp. 635-642
-
-
Koizumi, S.1
Suzuki, K.2
Ogra, Y.3
Yamada, H.4
Otsuka, F.5
-
16
-
-
4344586103
-
Metal-responsive transcription factor-1 (MTF-1) selects different types of metal response elements at low vs. high zinc concentration
-
DOI 10.1515/BC.2004.077
-
Wang, Y., Lorenzi, I., Georgiev, O. and Schaffner, W. (2004) Metal-responsive transcription factor-1 (MTF-1) selects different types of metal response elements at low vs. high zinc concentration. Biol. Chem., 385, 623-632. (Pubitemid 39144944)
-
(2004)
Biological Chemistry
, vol.385
, Issue.7
, pp. 623-632
-
-
Wang, Y.1
Lorenzi, I.2
Georgiev, O.3
Schaffner, W.4
-
17
-
-
33646935780
-
Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1
-
DOI 10.1093/emboj/17.10.2846
-
Gunes, C., Heuchel, R., Georgiev, O., Muller, K. H., Lichtlen, P., Bluthmann, H., Marino, S., Aguzzi, A. and Schaffner, W. (1998) Embryonic lethality and liver degeneration in mice lacking the metalresponsive transcriptional activator MTF-1. EMBO J., 17, 2846-2854. (Pubitemid 28227131)
-
(1998)
EMBO Journal
, vol.17
, Issue.10
, pp. 2846-2854
-
-
Gunes, C.1
Heuchel, R.2
Georgiev, O.3
Muller, K.-H.4
Lichtlen, P.5
Bluthmann, H.6
Marino, S.7
Aguzzi, A.8
Schaffner, W.9
-
18
-
-
26944485546
-
Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione
-
DOI 10.1093/nar/gki881
-
Wimmer, U., Wang, Y., Georgiev, O. and Schaffner, W. (2005) Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. Nucleic. Acids Res., 33, 5715-5727. (Pubitemid 41742592)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.18
, pp. 5715-5727
-
-
Wimmer, U.1
Wang, Y.2
Georgiev, O.3
Schaffner, W.4
-
19
-
-
0030909001
-
Reversible activation of mouse metal response element-binding transcription factor 1 DNA binding involves zinc interaction with the zinc finger domain
-
Dalton, T. P., Bittel, D. and Andrews, G. K. (1997) Reversible activation of mouse metal response element-binding transcription factor 1 DNA binding involves zinc interaction with the zinc finger domain. Mol. Cell. Biol., 17, 2781-2789. (Pubitemid 27175161)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.5
, pp. 2781-2789
-
-
Dalton, T.P.1
Bittel, D.2
Andrews, G.K.3
-
20
-
-
0032549517
-
The DNA binding activity of metal response element-binding transcription factor-1 is activated in vivo and in vitro by zinc, but not by other transition metals
-
DOI 10.1074/jbc.273.12.7127
-
Bittel, D., Dalton, T., Samson, S. L., Gedamu, L. and Andrews, G. K. (1998) The DNA binding activity of metal response element-binding transcription factor-1 is activated in vivo and in vitro by zinc, but not by other transition metals. J. Biol. Chem., 273, 7127-7133. (Pubitemid 28160385)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.12
, pp. 7127-7133
-
-
Bittel, D.1
Dalton, T.2
Samson, S.L.-A.3
Gedamu, L.4
Andrews, G.K.5
-
21
-
-
0037100631
-
Mammalian metal response element-binding transcription factor-1 functions as a zinc sensor in yeast, but not as a sensor of cadmium or oxidative stress
-
Daniels, P. J., Bittel, D., Smirnova, I. V., Winge, D. R. and Andrews, G. K. (2002) Mammalian metal response element-binding transcription factor-1 functions as a zinc sensor in yeast, but not as a sensor of cadmium or oxidative stress. Nucleic. Acids Res., 30, 3130-3140. (Pubitemid 34846177)
-
(2002)
Nucleic Acids Research
, vol.30
, Issue.14
, pp. 3130-3140
-
-
Daniels, P.J.1
Bittel, D.2
Smirnova, I.V.3
Winge, D.R.4
Andrews, G.K.5
-
22
-
-
0242637400
-
2 in vitro is modulated by metallothionein
-
2 in vitro is modulated by metallothionein. Mol. Cell. Biol., 23, 8471-8485.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8471-8485
-
-
Zhang, B.1
Georgiev, O.2
Hagmann, M.3
Gunes, C.4
Cramer, M.5
Faller, P.6
Vasak, M.7
Schaffner, W.8
-
23
-
-
49049109504
-
Regulation of ZIP and ZnT zinc transporters in zebrafish gill: Zinc repression of ZIP10 transcription by an intronic MRE cluster
-
Zheng, D., Feeney, G. P., Kille, P. and Hogstrand, C. (2008) Regulation of ZIP and ZnT zinc transporters in zebrafish gill: zinc repression of ZIP10 transcription by an intronic MRE cluster. Physiol. Genomics, 34, 205-214.
-
(2008)
Physiol. Genomics
, vol.34
, pp. 205-214
-
-
Zheng, D.1
Feeney, G.P.2
Kille, P.3
Hogstrand, C.4
-
24
-
-
0029009956
-
Functional domains of the heavy metal-responsive transcription regulator MTF-1
-
Radtke, F., Georgiev, O., Muller, H. P., Brugnera, E. and Schaffner, W. (1995) Functional domains of the heavy metal-responsive transcription regulator MTF-1. Nucleic. Acids Res., 23, 2277-2286.
-
(1995)
Nucleic. Acids Res.
, vol.23
, pp. 2277-2286
-
-
Radtke, F.1
Georgiev, O.2
Muller, H.P.3
Brugnera, E.4
Schaffner, W.5
-
25
-
-
0027329028
-
Distinct metal binding configurations in ACE1
-
Dameron, C. T., George, G. N., Arnold, P., Santhanagopalan, V. and Winge, D. R. (1993) Distinct metal binding configurations in ACE1. Bio-chemistry, 32, 7294-7301. (Pubitemid 23223135)
-
(1993)
Biochemistry
, vol.32
, Issue.28
, pp. 7294-7301
-
-
Dameron, C.T.1
George, G.N.2
Arnold, P.3
Santhanagopalan, V.4
Winge, D.R.5
-
26
-
-
0031961714
-
Copper-regulatory domain involved in gene expression
-
Winge, D. R. (1998) Copper-regulatory domain involved in gene expression. Prog. Nucleic. Acid Res. Mol. Biol., 58, 165-195.
-
(1998)
Prog. Nucleic. Acid Res. Mol. Biol.
, vol.58
, pp. 165-195
-
-
Winge, D.R.1
-
27
-
-
0037150092
-
Structures of the cuprous-thiolate clusters of the Mac1 and Ace1 transcriptional activators
-
Brown, K. R., Keller, G. L., Pickering, I. J., Harris, H. H., George, G. N. and Winge, D. R. (2002) Structures of the cuprous-thiolate clusters of the Mac1 and Ace1 transcriptional activators. Biochemistry, 41, 6469-6476.
-
(2002)
Biochemistry
, vol.41
, pp. 6469-6476
-
-
Brown, K.R.1
Keller, G.L.2
Pickering, I.J.3
Harris, H.H.4
George, G.N.5
Winge, D.R.6
-
28
-
-
0032508398
-
Structural and functional heterogeneity among the zinc fingers of human MRE-binding transcription factor-1
-
DOI 10.1021/bi980843r
-
Chen, X., Agarwal, A. and Giedroc, D. P. (1998) Structural and functional heterogeneity among the zinc fingers of human MRE-binding transcription factor-1. Biochemistry, 37, 11152-11161. (Pubitemid 28394863)
-
(1998)
Biochemistry
, vol.37
, Issue.32
, pp. 11152-11161
-
-
Chen, X.1
Agarwal, A.2
Giedroc, D.P.3
-
29
-
-
23344449523
-
The six zinc fingers of metal-responsive element binding transcription factor-1 form stable and quasi-ordered structures with relatively small differences in zinc affinities
-
DOI 10.1074/jbc.M505217200
-
Potter, B. M., Feng, L. S., Parasuram, P., Matskevich, V. A., Wilson, J. A., Andrews, G. K. and Laity, J. H. (2005) The six zinc fingers of metalresponsive element binding transcription factor-1 form stable and quasi-ordered structures with relatively small differences in zinc affinities. J. Biol. Chem., 280, 28529-28540. (Pubitemid 41105753)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.31
, pp. 28529-28540
-
-
Potter, B.M.1
Feng, L.S.2
Parasuram, P.3
Matskevichi, V.A.4
Wilson, J.A.5
Andrews, G.K.6
Laity, J.H.7
-
30
-
-
0033613267
-
MRE-binding transcription factor-1: Weak zinc-binding finger domains 5 and 6 modulate the structure, affinity, and specificity of the metal-response element complex
-
Chen, X., Chu, M. and Giedroc, D. P. (1999) MRE-binding transcription factor-1: weak zinc-binding finger domains 5 and 6 modulate the structure, affinity, and specificity of the metal-response element complex. Biochemistry, 38, 12915-12925. (Pubitemid 129515590)
-
(1999)
Biochemistry
, vol.38
, Issue.39
, pp. 12915-12925
-
-
Chen, X.1
Chu, M.2
Giedroc, D.P.3
-
31
-
-
0034711238
-
Functional heterogeneity in the zinc fingers of metalloregulatory protein metal response element-binding transcription factor-1
-
DOI 10.1074/jbc.M003863200
-
Bittel, D. C., Smirnova, I. V. and Andrews, G. K. (2000) Functional heterogeneity in the zinc fingers of metalloregulatory protein metal response element-binding transcription factor-1. J. Biol. Chem., 275, 37194-37201. (Pubitemid 32002139)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.47
, pp. 37194-37201
-
-
Bittel, D.C.1
Smirnova, I.V.2
Andrews, G.K.3
-
32
-
-
0033769166
-
Roles of zinc fingers and other regions of the transcription factor human MTF-1 in zinc-regulated DNA binding
-
DOI 10.1002/1097-4652(200012)185:3<464::AID-JCP18>3.0.CO;2-4
-
Koizumi, S., Suzuki, K., Ogra, Y., Gong, P. and Otuska, F. (2000) Roles of zinc fingers and other regions of the transcription factor human MTF-1 in zinc-regulated DNA binding. J. Cell. Physiol., 185, 464-472. (Pubitemid 30824253)
-
(2000)
Journal of Cellular Physiology
, vol.185
, Issue.3
, pp. 464-472
-
-
Koizumi, S.1
Suzuki, K.2
Ogra, Y.3
Gong, P.4
Otuska, F.5
-
33
-
-
2442425377
-
Metal ion affinities of the zinc finger domains of the metal responsive element-binding transcription factor-1 (MTF1)
-
Guerrerio, A. L. and Berg, J. M. (2004) Metal ion affinities of the zinc finger domains of the metal responsive element-binding transcription factor-1 (MTF1). Biochemistry, 43, 5437-5444.
-
(2004)
Biochemistry
, vol.43
, pp. 5437-5444
-
-
Guerrerio, A.L.1
Berg, J.M.2
-
34
-
-
23144453499
-
NMR assignment of the six zinc fingers of MTF-1 in the free and DNA-bound states
-
Potter, B. M., Knudsen, N. A., Feng, L. S., Matskevich, V. A., Wilson, J. A., Andrews, G. K. and Laity, J. H. (2005) NMR assignment of the six zinc fingers of MTF-1 in the free and DNA-bound states. J. Biomol. NMR, 32, 94.
-
(2005)
J. Biomol. NMR
, vol.32
, pp. 94
-
-
Potter, B.M.1
Knudsen, N.A.2
Feng, L.S.3
Matskevich, V.A.4
Wilson, J.A.5
Andrews, G.K.6
Laity, J.H.7
-
35
-
-
33746485592
-
The zinc-sensing mechanism of mouse MTF-1 involves linker peptides between the zinc fingers
-
DOI 10.1128/MCB.00471-06
-
Li, Y., Kimura, T., Laity, J. H. and Andrews, G. K. (2006) The zinc-sensing mechanism ofmouseMTF-1 involves linker peptides between the zinc fingers. Mol. Cell. Biol., 26, 5580-5587. (Pubitemid 44134316)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.15
, pp. 5580-5587
-
-
Li, Y.1
Kimura, T.2
Laity, J.H.3
Andrews, G.K.4
-
36
-
-
1042289756
-
A Novel Cysteine Cluster in Human Metal-responsive Transcription Factor 1 Is Required for Heavy Metal-induced Transcriptional Activation in Vivo
-
DOI 10.1074/jbc.M308924200
-
Chen, X., Zhang, B., Harmon, P. M., Schaffner, W., Peterson, D. O. and Giedroc, D. P. (2004) A novel cysteine cluster in human metal-responsive transcription factor 1 is required for heavy metalinduced transcriptional activation in vivo. J. Biol. Chem., 279, 4515-4522. (Pubitemid 38199042)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4515-4522
-
-
Chen, X.1
Zhang, B.2
Harmon, P.M.3
Schaffner, W.4
Peterson, D.O.5
Giedroc, D.P.6
-
37
-
-
44349173738
-
Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster
-
DOI 10.1093/nar/gkn103
-
Chen, X., Hua, H., Balamurugan, K., Kong, X., Zhang, L., George, G. N., Georgiev, O., Schaffner, W. and Giedroc, D. P. (2008) Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster. Nucleic. Acids Res., 36, 3128-3138. (Pubitemid 351737204)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.9
, pp. 3128-3138
-
-
Chen, X.1
Hua, H.2
Balamurugan, K.3
Kong, X.4
Zhang, L.5
George, G.N.6
Georgiev, O.7
Schaffner, W.8
Giedroc, D.P.9
-
38
-
-
0031583990
-
Metal-induced metallothionein gene expression can be inactivated by protein kinase C inhibitor
-
DOI 10.1016/S0014-5793(97)01489-0, PII S0014579397014890
-
Yu, C. W., Chen, J. H. and Lin, L. Y. (1997) Metalinduced metallothionein gene expression can be in-activated by protein kinase C inhibitor. FEBS Lett., 420, 69-73. (Pubitemid 28037202)
-
(1997)
FEBS Letters
, vol.420
, Issue.1
, pp. 69-73
-
-
Yu, C.-W.1
Chen, J.-H.2
Lin, L.-Y.3
-
39
-
-
0035834763
-
Phosphorylation Is Involved in the Activation of Metal-regulatory Transcription Factor I in Response to Metal Ions
-
DOI 10.1074/jbc.M108313200
-
LaRochelle, O., Gagne, V., Charron, J., Soh, J. W. and Seguin, C. (2001) Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions. J. Biol. Chem., 276, 41879-41888. (Pubitemid 37371086)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.45
, pp. 41879-41888
-
-
Larochelle, O.1
Gagne, V.2
Charron, J.3
Soh, J.-W.4
Seguin, C.5
-
40
-
-
0035816670
-
Nucleo-cytoplasmic Trafficking of Metal-regulatory Transcription Factor 1 is Regulated by Diverse Stress Signals
-
DOI 10.1074/jbc.M009154200
-
Saydam, N., Georgiev, O., Nakano, M. Y., Greber, U. F. and Schaffner, W. (2001) Nucleo-cytoplasmic trafficking of metal-regulatory transcription factor 1 is regulated by diverse stress signals. J. Biol. Chem., 276, 25487-25495. (Pubitemid 37413038)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.27
, pp. 25487-25495
-
-
Saydam, N.1
Georgiev, O.2
Nakano, M.Y.3
Greber, U.F.4
Schaffner, W.5
-
41
-
-
0036805109
-
Activation of gene expression by metal-responsive signal transduction pathways
-
Adams, T. K., Saydam, N., Steiner, F., Schaffner, W. and Freedman, J. H. (2002) Activation of gene expression by metal-responsive signal transduction pathways. Environ. Health Perspect., 110(Suppl 5), 813-817. (Pubitemid 35276872)
-
(2002)
Environmental Health Perspectives
, vol.110
, Issue.SUPPL. 5
, pp. 813-817
-
-
Adams, T.K.1
Saydam, N.2
Steiner, F.3
Schaffner, W.4
Freedman, J.H.5
-
42
-
-
4344716723
-
Gene- And cell-type-specific effects of signal transduction cascades on metal-regulated gene transcription appear to be independent of changes in the phosphorylation of metal-response-element-binding transcription factor-1
-
DOI 10.1042/BJ20040504
-
Jiang, H., Fu, K. and Andrews, G. K. (2004) Geneand cell-type-specific effects of signal transduction cascades on metal-regulated gene transcription appear to be independent of changes in the phosphorylation of metal-response-element-binding transcription factor-1. Biochem. J., 382, 33-41. (Pubitemid 39141563)
-
(2004)
Biochemical Journal
, vol.382
, Issue.1
, pp. 33-41
-
-
Jiang, H.1
Fu, K.2
Andrews, G.K.3
-
43
-
-
0021112017
-
Mouse hepatic metallothionein-I gene cleavage by micrococcal nuclease is enhanced after induction by cadmium
-
Koropatnick, J., Andrews, G., Duerksen, J. D., Varshney, U. and Gedamu, L. (1983) Mouse hepatic metallothionein-I gene cleavage by micrococcal nuclease is enhanced after induction by cadmium. Nucleic. Acids Res., 11, 3255-3267.
-
(1983)
Nucleic. Acids Res.
, vol.11
, pp. 3255-3267
-
-
Koropatnick, J.1
Andrews, G.2
Duerksen, J.D.3
Varshney, U.4
Gedamu, L.5
-
44
-
-
14544308853
-
Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes
-
DOI 10.1016/j.bbaexp.2004.10.005, PII S0167478104002349
-
Mohrmann, L. and Verrijzer, C. P. (2005) Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes. Biochim. Biophys. Acta, 1681, 59-73. (Pubitemid 41071379)
-
(2005)
Biochimica et Biophysica Acta - Gene Structure and Expression
, vol.1681
, Issue.2-3
, pp. 59-73
-
-
Mohrmann, L.1
Verrijzer, C.P.2
-
45
-
-
0034068906
-
Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene
-
DOI 10.1128/MCB.20.8.2839-2851.2000
-
de La Serna, I. L., Carlson, K. A., Hill, D. A., Guidi, C. J., Stephenson, R. O., Sif, S., Kingston, R. E. and Imbalzano, A. N. (2000) Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene. Mol. Cell. Biol., 20, 2839-2851. (Pubitemid 30183503)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.8
, pp. 2839-2851
-
-
De La Serna, I.L.1
Carlson, K.A.2
Hill, D.A.3
Guidi, C.J.4
Stephenson, R.O.5
Sif, S.6
Kingston, R.E.7
Imbalzano, A.N.8
-
46
-
-
33750308605
-
BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress
-
DOI 10.1128/MCB.00700-06
-
Zhang, J., Ohta, T., Maruyama, A., Hosoya, T., Nishikawa, K., Maher, J. M., Shibahara, S., Itoh, K. and Yamamoto, M. (2006) BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress. Mol. Cell. Biol., 26, 7942-7952. (Pubitemid 44630994)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.21
, pp. 7942-7952
-
-
Zhang, J.1
Ohta, T.2
Maruyama, A.3
Hosoya, T.4
Nishikawa, K.5
Maher, J.M.6
Shibahara, S.7
Itoh, K.8
Yamamoto, M.9
-
47
-
-
0036889153
-
Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure
-
DOI 10.1128/MCB.22.23.8302-8319.2002
-
Ghoshal, K., Datta, J., Majumder, S., Bai, S., Dong, X., Parthun, M. and Jacob, S. T. (2002) Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factorMTF- 1 and forming an open chromatin structure. Mol. Cell. Biol., 22, 8302-8319. (Pubitemid 35304062)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.23
, pp. 8302-8319
-
-
Ghoshal, K.1
Datta, J.2
Majumder, S.3
Bai, S.4
Dong, X.5
Parthun, M.6
Jacob, S.T.7
-
48
-
-
33646819033
-
A folate- And methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats
-
Majumder, S., Kutay, H., Datta, J., Summers, D., Jacob, S. T. and Ghoshal, K. (2006) Epigenetic regulation of metallothionein-I gene expression: differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins. J. Cell. Biochem., 97, 1300-1316. (Pubitemid 43765356)
-
(2006)
Journal of Nutrition
, vol.136
, Issue.6
, pp. 1522-1527
-
-
Ghoshal, K.1
Li, X.2
Datta, J.3
Bai, S.4
Pogribny, I.5
Pogribny, M.6
Huang, Y.7
Young, D.8
Jacob, S.T.9
-
49
-
-
43749091982
-
Nuclear factor-1 and metal transcription factor-1 synergistically activate the mouse metallothionein-1 gene in response to metal ions
-
LaRochelle, O., Labbe, S., Harrisson, J. F., Simard, C., Tremblay, V., St-Gelais, G., Govindan, M. V. and Seguin, C. (2008) Nuclear factor-1 and metal transcription factor-1 synergistically activate the mouse metallothionein-1 gene in response to metal ions. J. Biol. Chem., 283, 8190-8201.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 8190-8201
-
-
LaRochelle, O.1
Labbe, S.2
Harrisson, J.F.3
Simard, C.4
Tremblay, V.5
St-Gelais, G.6
Govindan, M.V.7
Seguin, C.8
-
50
-
-
34047263219
-
Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade
-
DOI 10.1158/0008-5472.CAN-06-4433
-
Datta, J., Majumder, S., Kutay, H., Motiwala, T., Frankel,W., Costa, R., Cha, H. C., MacDougald, O. A., Jacob, S. T. and Ghoshal, K. (2007) Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade. Cancer Res., 67, 2736-2746. (Pubitemid 46548962)
-
(2007)
Cancer Research
, vol.67
, Issue.6
, pp. 2736-2746
-
-
Datta, J.1
Majumder, S.2
Kutay, H.3
Motiwala, T.4
Frankel, W.5
Costa, R.6
Cha, H.C.7
MacDougald, O.A.8
Jacob, S.T.9
Ghoshal, K.10
-
51
-
-
40949105551
-
Metallothionein induction by hypoxia involves cooperative interactions between metal-responsive transcription factor-1 and hypoxia-inducible transcription factor-1alpha
-
Murphy, B. J., Kimura, T., Sato, B. G., Shi, Y. and Andrews, G. K. (2008) Metallothionein induction by hypoxia involves cooperative interactions between metal-responsive transcription factor-1 and hypoxia-inducible transcription factor-1alpha. Mol. Cancer Res., 6, 483-490.
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 483-490
-
-
Murphy, B.J.1
Kimura, T.2
Sato, B.G.3
Shi, Y.4
Andrews, G.K.5
-
52
-
-
0042858186
-
Heat and heavy metal stress synergize to mediate transcriptional hyperactivation by metal-responsive transcription factor MTF-1
-
DOI 10.1074/jbc.M302138200
-
Saydam, N., Steiner, F., Georgiev, O. and Schaffner, W. (2003) Heat and heavy metal stress synergize to mediate transcriptional hyperactivation by metalresponsive transcription factor MTF-1. J. Biol. Chem., 278, 31879-31883. (Pubitemid 37048372)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.34
, pp. 31879-31883
-
-
Saydam, N.1
Steiner, F.2
Georgiev, O.3
Schaffner, W.4
-
53
-
-
32344444550
-
Cross talk of heat shock and heavy metal regulatory pathways
-
DOI 10.1016/j.bbrc.2006.01.066, PII S0006291X06001525
-
Uenishi, R., Gong, P., Suzuki, K. and Koizumi, S. (2006) Cross talk of heat shock and heavy metal regulatory pathways. Biochem. Biophys. Res. Commun., 341, 1072-1077. (Pubitemid 43221775)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.341
, Issue.4
, pp. 1072-1077
-
-
Uenishi, R.1
Gong, P.2
Suzuki, K.3
Koizumi, S.4
-
54
-
-
0035844286
-
Negative Regulatory Role of Sp1 in Metal Responsive Element-mediated Transcriptional Activation
-
DOI 10.1074/jbc.M100570200
-
Ogra, Y., Suzuki, K., Gong, P., Otsuka, F. and Koizumi, S. (2001) Negative regulatory role of Sp1 in metal responsive element-mediated transcriptional activation. J. Biol. Chem., 276, 16534-16539. (Pubitemid 37391704)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.19
, pp. 16534-16539
-
-
Ogra, Y.1
Suzuki, K.2
Gong, P.3
Otsuka, F.4
Koizumi, S.5
-
55
-
-
0345531101
-
Dynamics of the metal-dependent transcription factor complex in vivo at themousemetallothionein-I promoter
-
Daniels, P. J. and Andrews, G. K. (2003) Dynamics of the metal-dependent transcription factor complex in vivo at themousemetallothionein-I promoter. Nucleic. Acids Res., 31, 6710-6721.
-
(2003)
Nucleic. Acids Res.
, vol.31
, pp. 6710-6721
-
-
Daniels, P.J.1
Andrews, G.K.2
-
56
-
-
0035283151
-
The transcription factors MTF-1 and USF1 cooperate to regulate mouse metallothionein-I expression in response to the essential metal zinc in visceral endoderm cells during early development
-
DOI 10.1093/emboj/20.5.1114
-
Andrews, G. K., Lee, D. K., Ravindra, R., Lichtlen, P., Sirito, M., Sawadogo, M. and Schaffner, W. (2001) The transcription factors MTF-1 and USF1 cooperate to regulate mouse metallothionein-I expression in response to the essential metal zinc in visceral endoderm cells during early development. EMBO J., 20, 1114-1122. (Pubitemid 32186801)
-
(2001)
EMBO Journal
, vol.20
, Issue.5
, pp. 1114-1122
-
-
Andrews, G.K.1
Lee, D.K.2
Ravindra, R.3
Lichtlen, P.4
Sirito, M.5
Sawadogo, M.6
Schaffner, W.7
-
57
-
-
26844516068
-
NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells
-
DOI 10.1515/BC.2005.101
-
Cramer, M., Nagy, I., Murphy, B. J., Gassmann, M., Hottiger, M. O., Georgiev, O. and Schaffner, W. (2005) NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells. Biol. Chem., 386, 865-872. (Pubitemid 41448142)
-
(2005)
Biological Chemistry
, vol.386
, Issue.9
, pp. 865-872
-
-
Cramer, M.1
Nagy, I.2
Murphy, B.J.3
Gassmann, M.4
Hottiger, M.O.5
Georgiev, O.6
Schaffner, W.7
-
58
-
-
46149123860
-
Zinc-induced formation of a coactivator complex containing the zinc-sensing transcription factor MTF-1, p300/CBP, and Sp1
-
DOI 10.1128/MCB.00369-08
-
Li, Y., Kimura, T., Huyck, R. W., Laity, J. H. and Andrews, G. K. (2008) Zinc-induced formation of a co-activator complex containing the zincsensing transcription factor MTF-1, p300/CBP and Sp1. Mol. Cell. Biol., 28, 4275-4284. (Pubitemid 351904950)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.13
, pp. 4275-4284
-
-
Li, Y.1
Kimura, T.2
Huyck, R.W.3
Laity, J.H.4
Andrews, G.K.5
-
59
-
-
33744821893
-
Coactivator cross-talk specifies transcriptional output
-
Marr, M. T., 2nd, Isogai, Y., Wright, K. J. and Tjian, R. (2006) Coactivator cross-talk specifies transcriptional output. Genes Dev., 20, 1458-1469.
-
(2006)
Genes Dev.
, vol.20
, pp. 1458-1469
-
-
Marr II, M.T.1
Isogai, Y.2
Wright, K.J.3
Tjian, R.4
-
60
-
-
0034916613
-
p300/CBP proteins: HATs for transcriptional bridges and scaffolds
-
Chan, H. M. and La Thangue, N. B. (2001) p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J. Cell Sci., 114, 2363-2373.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2363-2373
-
-
Chan, H.M.1
La Thangue, N.B.2
-
61
-
-
0029910072
-
Oxidative stress activates metal-responsive transcription factor-1 binding activity. Occupancy in vivo of metal response elements in the metallothionein-I gene promoter
-
DOI 10.1074/jbc.271.42.26233
-
Dalton, T. P., Li, Q., Bittel, D., Liang, L. and Andrews, G. K. (1996) Oxidative stress activates metal-responsive transcription factor-1 binding activity. Occupancy in vivo of metal response elements in the metallothionein-I gene promoter. J. Biol. Chem., 271, 26233-26241. (Pubitemid 26347472)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.42
, pp. 26233-26241
-
-
Dalton, T.P.1
Li, Q.2
Bittel, D.3
Liang, L.4
Andrews, G.K.5
-
62
-
-
0033990794
-
Regulation of metallothionein gene expression by oxidative stress and metal ions
-
Andrews, G. K. (2000) Regulation of metallothionein gene expression by oxidative stress and metal ions. Biochem. Pharmacol., 59, 95-104.
-
(2000)
Biochem. Pharmacol.
, vol.59
, pp. 95-104
-
-
Andrews, G.K.1
-
63
-
-
0033559578
-
Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1
-
Murphy, B. J., Andrews, G. K., Bittel, D., Discher, D. J., McCue, J., Green, C. J., Yanovsky, M., Giaccia, A., Sutherland, R. M., Laderoute, K. R. and Webster, K. A. (1999) Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1. Cancer Res., 59, 1315-1322. (Pubitemid 29136264)
-
(1999)
Cancer Research
, vol.59
, Issue.6
, pp. 1315-1322
-
-
Murphy, B.J.1
Andrews, G.K.2
Bittel, D.3
Discher, D.J.4
McCue, J.5
Green, C.J.6
Yanovsky, M.7
Giaccia, A.8
Sutherland, R.M.9
Laderoute, K.R.10
Webster, K.A.11
-
64
-
-
60549113516
-
Metal response element-binding transcription factor-1 is activated by degradation of metallothionein
-
Kimura, T., Okumura, F., Oguro, I., Nakanishi, T., Sone, T., Isobe, M., Tanaka, K. and Itoh, N. (2009) Metal response element-binding transcription factor-1 is activated by degradation of metallothionein. J. Health Sci., 55, 1-5.
-
(2009)
J. Health Sci.
, vol.55
, pp. 1-5
-
-
Kimura, T.1
Okumura, F.2
Oguro, I.3
Nakanishi, T.4
Sone, T.5
Isobe, M.6
Tanaka, K.7
Itoh, N.8
-
65
-
-
0035312722
-
Target gene search for the metal-responsive transcription factor MTF-1
-
Lichtlen, P., Wang, Y., Belser, T., Georgiev, O., Certa, U., Sack, R. and Schaffner, W. (2001) Target gene search for the metal-responsive transcription factor MTF-1. Nucleic. Acids Res., 29, 1514-1523. (Pubitemid 32288499)
-
(2001)
Nucleic Acids Research
, vol.29
, Issue.7
, pp. 1514-1523
-
-
Lichtlen, P.1
Wang, Y.2
Belser, T.3
Georgiev, O.4
Certa, U.5
Sack, R.6
Schaffner, W.7
-
66
-
-
3042738968
-
Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver
-
DOI 10.1096/fj.03-1282com
-
Wang, Y., Wimmer, U., Lichtlen, P., Inderbitzin, D., Stieger, B., Meier, P. J., Hunziker, L., Stallmach, T., Forrer, R., Rulicke, T., Georgiev, O. and Schaffner, W. (2004) Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxifica tion in the adult liver. FASEB J., 18, 1071-1079. (Pubitemid 38859215)
-
(2004)
FASEB Journal
, vol.18
, Issue.10
, pp. 1071-1079
-
-
Wang, Y.1
Wimmer, U.2
Lichtlen, P.3
Inderbitzin, D.4
Stieger, B.5
Meier, P.J.6
Hunziker, L.7
Stallmach, T.8
Forrer, R.9
Rulicke, T.10
Georgiev, O.11
Schaffner, W.12
-
67
-
-
33748930954
-
Role of metal-responsive transcription factor-1 (MTF-1) in EGF-dependent DNA synthesis in primary hepatocytes
-
DOI 10.1002/jcb.20948
-
Kimura, T., Itoh, N., Sone, T., Kondoh, M., Tanaka, K. and Isobe, M. (2006) Role of metal-responsive transcription factor-1 (MTF-1) in EGF-dependent DNA synthesis in primary hepatocytes. J. Cell. Biochem., 99, 485-494. (Pubitemid 44435565)
-
(2006)
Journal of Cellular Biochemistry
, vol.99
, Issue.2
, pp. 485-494
-
-
Kimura, T.1
Itoh, N.2
Sone, T.3
Kondoh, M.4
Tanaka, K.5
Isobe, M.6
-
68
-
-
3442900447
-
Loss of metal transcription factor-1 suppresses tumor growth through enhanced matrix deposition
-
DOI 10.1096/fj.03-1205com
-
Haroon, Z. A., Amin, K., Lichtlen, P., Sato, B., Huynh, N. T., Wang, Z., Schaffner, W. and Murphy, B. J. (2004) Loss of metal transcription factor-1 suppresses tumor growth through enhanced matrix deposition. FASEB J., 18, 1176-1184. (Pubitemid 39006879)
-
(2004)
FASEB Journal
, vol.18
, Issue.11
, pp. 1176-1184
-
-
Haroon, Z.A.1
Amin, K.2
Lichtlen, P.3
Sato, B.4
Huynh, N.T.5
Wang, Z.6
Schaffner, W.7
Murphy, B.J.8
-
69
-
-
19944433274
-
Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1)
-
DOI 10.1038/sj.onc.1208197
-
Tamura, Y., Maruyama, M., Mishima, Y., Fujisawa, H., Obata, M.,Kodama, Y.,Yoshikai, Y., Aoyagi, Y., Niwa, O., Schaffner, W. and Kominami, R. (2005) Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1). Oncogene, 24, 399-406. (Pubitemid 40188588)
-
(2005)
Oncogene
, vol.24
, Issue.3
, pp. 399-406
-
-
Tamura, Y.1
Maruyama, M.2
Mishima, Y.3
Fujisawa, H.4
Obata, M.5
Kodama, Y.6
Yoshikai, Y.7
Aoyagi, Y.8
Niwa, O.9
Schaffner, W.10
Kominami, R.11
-
70
-
-
58149152752
-
Chromium(VI) inhibits mouse metallothionein-I gene transcription by preventing the zinc-dependent formation of an MTF-1-p300 complex
-
Kimura, T., Li, Y., Okumura, F., Itoh, N., Nakanishi, T., Sone, T., Isobe, M. and Andrews, G. K. (2008) Chromium(VI) inhibits mouse metallothionein-I gene transcription by preventing the zinc-dependent formation of an MTF-1-p300 complex. Biochem. J., 415, 477-482.
-
(2008)
Biochem. J.
, vol.415
, pp. 477-482
-
-
Kimura, T.1
Li, Y.2
Okumura, F.3
Itoh, N.4
Nakanishi, T.5
Sone, T.6
Isobe, M.7
Andrews, G.K.8
|