Imatinib attenuates skeletal muscle dystrophy in mdx mice

FASEB Journal

Volumn 23, Issue 8, 2009, Pages 2539-2548

  Huang, Ping ^a   Zhao, Xinyu S ^a   Fields, Matthew ^a   Ransohoff, Richard M ^a   Zhou, Lan ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

c abl; Fibrosis; Inflammation; Necrosis; PDGF; TGF

Indexed keywords

ABELSON KINASE; CD45 ANTIGEN; COLLAGEN TYPE 3; CREATINE KINASE; FIBRONECTIN; IMATINIB; INTERLEUKIN 1BETA; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN TYROSINE KINASE; SMAD2 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; MESSENGER RNA; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE; SMAD2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIAPHRAGM; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; DUCHENNE MUSCULAR DYSTROPHY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; FIBROBLAST; GENE EXPRESSION; GRIP STRENGTH; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOUSE; MUSCLE FUNCTION; MUSCLE NECROSIS; MYOFIBROSIS; MYOSITIS; NONHUMAN; PERITONEUM MACROPHAGE; PERITONITIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; WESTERN BLOTTING; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE; ANIMAL; ANIMAL MUSCULAR DYSTROPHY; BLOOD; C57BL MOUSE; GENETICS; IN VITRO STUDY; INFLAMMATION; METABOLISM; MUSCLE STRENGTH; NECROSIS; NUCLEOTIDE SEQUENCE; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; SKELETAL MUSCLE;

ANIMALIA; MUS;

ANIMALS; BASE SEQUENCE; CREATINE KINASE; DIAPHRAGM; GENE EXPRESSION; INFLAMMATION; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MUSCLE STRENGTH; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; NECROSIS; PHOSPHORYLATION; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-ABL; PYRIMIDINES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RNA, MESSENGER; SMAD2 PROTEIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 68849130956     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-129833     Document Type: Article

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