Increase in decorin and biglycan in Duchenne muscular dystrophy: Role of fibroblasts as cell source of these proteoglycans in the disease

Journal of Cellular and Molecular Medicine

Volumn 10, Issue 3, 2006, Pages 758-769

  Fadic, Ricardo ^a   Mezzano, Valeria ^b   Alvarez, Karin ^b   Cabrera, Daniel ^b   Holmgren, Jenny ^c   Brandan, Enrique ^b  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c Dirección de Investigación y Desarrollo Instituto Teletón   (Chile)

Author keywords

Biglycan; Decorin; Duchenne muscular dystrophy; Interstitial fibrosis; Proteoglycans

Indexed keywords

BIGLYCAN; DECORIN; PROTEOGLYCAN; SCLEROPROTEIN;

ARTICLE; BIOPSY; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; CHILD; DUCHENNE MUSCULAR DYSTROPHY; FIBROBLAST; FIBROSIS; GENE EXPRESSION REGULATION; HUMAN; INTESTINE; MALE; METABOLISM; MUSCLE; PATHOLOGY; PRESCHOOL CHILD; SKELETAL MUSCLE;

BIOPSY; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; HUMANS; INTESTINES; MALE; MUSCLE, SKELETAL; MUSCLES; MUSCULAR DYSTROPHY, DUCHENNE; PROTEOGLYCANS;

EID: 33845308607     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2006.tb00435.x     Document Type: Article

References (54)

1. Bogdanovich S, Perkins KJ, Krag TO, Khurana TS. Therapeutics for Duchenne muscular dystrophy: current approaches and future directions. J Mol Med. 2004; 82: 102-15.
2. Monaco AP, Bertelson CJ, Middlesworth W, Colletti CA, Aldridge J, Fischbeck KH, Bartlett R, Pericak-Vance MA, Roses AD, Kunkel LM. Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment. Nature 1985; 316: 842-5.
3. van Deutekom JC, van Ommen GJ. Advances in Duchenne muscular dystrophy gene therapy. Nat Rev Genet. 2003; 4: 774-83.
4. Dubowitz V. Current and future therapy in muscular dystrophy; need for a common language between basic scientists and clinicians. Acta Myol. 2004; 23: V-IX.
5. Blake DJ. Dystrobrevin dynamics in muscle-cell signalling: a possible target for therapeutic intervention in Duchenne muscular dystrophy? Neuromuscul Disord. 2002; 12: 5110-7.
6. Matsumura K, Tome FM, Collin H, Leturcq F, Jeanpierre M, Kaplan JC, Fardeau M, Campbell KP. Expression of dystrophin-associated proteins in dystrophin-positive muscle fibers (revenants) in Duchenne muscular dystrophy. Neuromuscul Disord. 1994; 4: 115-20.
7. Bulfield G, Siller W, Wight P, Moore K. X chromosome-linked muscular dystrophy (mdx) in the mouse. Proc Natl Acad Sci USA. 1984; 81: 1189-92.
8. Rampoldi E, Meola G, Conti A, Velicogna M, Larizza L. A comparative analysis of collagen III, IV, laminin and fibronectin in Duchenne muscular dystrophy biopsies and cell cultures. Eur J Cell Biol. 1986; 42: 27-34.
9. Osses N, Brandan E. ECM is required for skeletal muscle differentiation independently of muscle regulatory factor expression. Am J Physiol Cell Physiol 2002; 282: C383-94.
10. Larrain J, Carey DJ, Brandan E. Syndecan-1 expression inhibits myoblast differentiation through a basic fibroblast growth factor-dependent mechanism. J Biol Chem. 1998; 273: 32288-96.
11. Fuentealba L, Carey DJ, Brandan E. Antisense inhibition of syndecan-3 expression during skeletal muscle differentiation accelerates myogenesis through a basic fibroblast growth factor-dependent mechanism. J Biol Chem. 1999; 274: 37876-84.
12. Caceres S, Cuellar C, Casar JC, Garrido J, Schaefer L, Kresse H, Brandan E. Synthesis of proteoglycans is augmented in dystrophic mdx mouse skeletal muscle. Eur J Cell Biol. 2000; 79: 173-81.
13. Iozzo RV. The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins. J Biol Chem. 1999; 274: 18843-6.
14. Gosselin LE, Williams JE, Decring M, Brazeau D, Koury S, Martinez DA. Localization and early time course of TGF-beta 1 mRNA expression in dystrophic muscle. Muscle Nerve 2004; 30: 645-53.
15. Bianco P, Fisher LW, Young MF, Termine JD, Robey PG. Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues. J Histochem Cytochem. 1990; 38: 1549-63.
16. Riquelme C, Larrain J, Schonherr E, Henriquez JP, Kresse H, Brandan E. Antisense inhibition of decorin expression in myoblasts decreases cell responsiveness to transforming growth factor beta and accelerates skeletal muscle differentiation. J Biol Chem. 2001; 276: 3589-96.
17. Bowe M, Mendis D, Fallon J. The small leucine-rich repeat proteoglycan biglycan binds to alpha-dystroglycan and is upregulated in dystrophic muscle. J Cell Biol. 2000; 148: 801-10.
18. Casar JC, McKechnie BA, Fallon JR, Young MF, Brandan E. Transient up-regulation of biglycan during skeletal muscle regeneration: delayed fiber growth along with decorin increase in biglycan-deficient mice. Dev Biol. 2004; 268: 358-71.
19. Suzuki K, Wang R, Kubota H, Shibuya H, Saegusa J, Sato T. Kinetics of biglycan, decorin and thrombospondin-1 in mercuric chloride-induced renal tubulointerstitial fibrosis. Exp Mol Pathol. 2005; 79: 68-73.
20. Kolb M, Margetts PJ, Sime PJ, Gauldie J. Proteoglycans decorin and biglycan differentially modulate TGF-beta- mediated fibrotic responses in the lung. Am J Physiol Lung Cell Mol Physiol. 2001; 280: L1327-34.
21. McCroskery S, Thomas M, Platt L, Hennebry A, Nishimura T, McLeay L, Sharma M, Kambadur R. Improved muscle healing through enhanced regeneration and reduced fibrosis in myostatin-null mice. J Cell Sci. 2005; 118: 3531-411.
22. Shimizu-Hirota R, Sasamura H, Kuroda M, Kobayashi E, Hayashi M, Saruta T. Extracellular matrix glycoprotein biglycan enhances vascular smooth muscle cell proliferation and migration. Circ Res. 2004; 94: 1067-74.
23. Haslett JN, Sanoudou D, Kho AT, Bennett RR, Greenberg SA, Kohane IS, Beggs AH, Kunkel LM. Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle. Proc Natl Acad Sci USA. 2002; 99: 15000-5.
24. Brandan E, Inestrosa NC. Isolation of the heparan sulfate proteoglycans from the extracellular matrix of rat skeletal muscle. J Neurobiol. 1987; 18: 271-82.
25. Brandan E, Fuentes ME, Andrade W. The proteoglycan decorin is synthesized and secreted by differentiated myotubes. Eur J Cell Biol. 1991; 55: 209-16.
26. rd, Young MF. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl. 1995;266:61-5.
27. Melone MA, Peluso G, Galderisi U, Petillo O, Cotrufo R. Increased expression of IGF-binding protein-5 in Duchenne muscular dystrophy (DMD) fibroblasts correlates with the fibroblast-induced downregulation of DMD myoblast growth: an in vitro analysis. J Cell Physiol. 2000; 185: 143-53.
28. Brandan E, Fuentes ME, Andrade W. Decorin, a chondroitin/dermatan sulfate proteoglycan is under neural control in rat skeletal muscle. J Neurosci Res. 1992; 32: 51-9.
29. Kinsella MG, Bressler SL, Wight TN. The regulated synthesis of versican, decorin, and biglycan: extracellular matrix proteoglycans that influence cellular phenotype. Clin Rev Eukaryot Gene Expr. 2004; 14: 203-34.
30. Higuchi I, Fukunaga H, Matsumura K, Inose M, Izumi K, Okubo R, Nakagawa M, Shimizu T, Osame M. Abnormal expression of heparin sulfate proteoglycan on basal lamina of muscle fibers in two Japanese patients with adhalin deficiency. Neuromuscul Disord. 1995; 5: 467-74.
31. Winokur ST, Barrett K, Martin JH, Forrester JR, Simon M, Tawil R, Chung SA, Masny PS, Figlewicz DA. Facioscapulohumeral muscular dystrophy (FSHD)-myoblasts demonstrate increased susceptibility to oxidative stress. Neuromuscul Disord. 2003; 13: 322-33.
32. Al Haj Zen A, Caligiuri G, Sainz J, Lemitre M, Demerens C, Lafont A. Decorin overexpression reduces atherosclerosis development in apolipoprotein E-deficient mice. Atherosclerosis 2005; In Press.
33. Weis SM, Zimmerman SD, Shah M, Covell JW, Omens JH, Ross J Jr, Dalton N, Jones Y, Reed CC, Iozzo RV, McCulloch AD. A role for decorin in the remodeling of myocardial infarction. Matrix Biol. 2005; 24: 313-24.
34. Grisanti S, Szurman P, Warga M, Kaczmarck R, Ziemssen F, Tatar O, Bartz-Schmidt KU. Decorin modulates wound healing in experimental glaucoma filtration surgery: a pilot study. Invest Ophthalmol Vis Sci. 2005; 46: 191-6.
35. Schaefer L, Macakova K, Raslik I, Micegova M, Grone HJ, Schonherr E, Robenck H, Echtermeyer FG, Grassel S, Bruckner P, Schaefer RM, Iozzo RV, Kresse H. Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction. Am J Pathol. 2002; 160: 1181-91.
36. Ishitobi M, Haginoya K, Zhao Y, Ohnuma A, Minato J, Yanagisawa T, Tanabu M, Kikuchi M, Iinuma K. Elevated plasma levels of transforming growth factor beta1 in patients with muscular dystrophy. Neuroreport 2000; 11: 4033-5.
37. Bernasconi P, Di Blasi C, Mora M, Morandi L, Galbiati S, Confalonieri P, Cornelio F, Mantegazza R. Transforming growth factor-beta1 and fibrosis in congenital muscular dystrophies. Neuromuscul Disord. 1999; 9: 28-33.
38. Droguett R, Cabello-Verrugio C, Riquelme C, Brandan E. Extracellular proteoglycans modifies TGF-beta bioavailability attenuating its signaling during skeletal muscle differentiation. Matrix Biol. 2006; In Press.
39. Hosaka Y, Kirisawa R, Mafune N, Takehana K. Downregulation of decorin and transforming growth factor-beta1 by decorin gene suppression in tendinocytes. Connect Tissue Res. 2005; 46: 18-26.
40. Li Y, Foster W, Deasy BM, Chan Y, Prisk V, Tang Y, Cummins J, Huard J. Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesis. Am J Pathol. 2004; 164: 1007-19.
41. Fukushima K, Badlani N, Usas A, Riano F, Fu F, Huard J. The use of an antifibrosis agent to improve muscle recovery after laceration. Am J Sports Med. 2001; 29: 394-402.
42. Sato K, Li Y, Foster W, Fukushima K, Badlani N, Adachi N, Usas A, Fu FH, Huard J. Improvement of muscle healing through enhancement of muscle regeneration and prevention of fibrosis. Muscle Nerve 2003; 28: 365-72.
43. Melone MA, Peluso G, Petillo O, Galderisi U, Cotrufo R. Defective growth in vitro of Duchenne Muscular Dystrophy myoblasts: the molecular and biochemical basis. J Cell Biochem. 1999; 76: 118-32.
44. Gosselin LE, McCormick KM. Targeting the immune system to improve ventilatory function in muscular dystrophy. Med Sci Sports Exerc. 2004; 36: 44-51.
45. Hogemann B, Edel G, Schwarz K, Krech R, Kresse H. Expression of biglycan, decorin and proteoglycan-100/CSF-1 in normal and fibrotic human liver. Pathol Res Pract. 1997; 193: 747-51.
46. Krull NB, Zimmermann T, Gressner AM. Spatial and temporal patterns of gene expression for the proteoglycans biglycan and decorin and for transforming growth factor-beta 1 revealed by in situ hybridization during experimentally induced liver fibrosis in the rat. Hepatology 1993; 18: 581-9.
47. Stokes MB, Holler S, Cui Y, Hudkins KL, Eitner F, Fogo A, Alpers CE. Expression of decorin, biglycan, and collagen type I in human renal fibrosing disease. Kidney Int. 2000; 57: 487-98.
48. Tufvesson E, Westergren-Thorsson G. Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migration. J Cell Sci. 2003; 116:4857-64.
49. Junghans U, Koops A, Westmeyer A, Kapplrr J, Meyer HE, Muller HW. Purification of a meningeal cell-derived chondroitin sulphate proteoglycan with neurotrophic activity for brain neurons and its identification as biglycan. Eur J Neurosci. 1995; 7: 2341-50.
50. Tiede K, Stoter K, Petrik C, Chen WB, Ungefroren H, Kruse ML, Stoll M, Unger T, Fischer JW. Angiotensin II AT(1)-receptor induces biglycan in neonatal cardiac fibroblasts via autocrine release of TGFbeta in vitro. Cardiovasc Res. 2003; 60: 538-46.
51. Kahari VM, Larjava H, Uitto J. Differential regulation of extracellular matrix proteoglycan (PG) gene expression. Transforming growth factor-beta 1 up-regulates biglycan (PGI), and versican (large fibroblast PG) but down-regulates decorin (PGII) mRNA levels in human fibroblasts in culture. J Biol Chem. 1991; 266: 10608-15.
52. Alvarez K, Fadic R, Brandan E. Augmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophy. J Cell Biochem. 2002; 85: 703-13.
53. Larrain J, Alvarez J, Hassell JR, Brandan E. Expression of perlecan, a proteoglycan that binds myogenic inhibitory basic fibroblast growth factor, is down regulated during skeletal muscle differentiation. Exp Cell Res. 1997; 234: 405-12.
54. Brandan E, Carey DJ, Larrain J, Melo F, Campos A. Synthesis and processing of glypican during differentiation of skeletal muscle cells. Eur J Cell Biol. 1996; 71: 170-6.