Optimization of d-amino acid oxidase for low substrate concentrations - Towards a cancer enzyme therapy

FEBS Journal

Volumn 276, Issue 17, 2009, Pages 4921-4932

  Rosini, Elena ^a   Pollegioni, Loredano ^a   Ghisla, Sandro ^a   Orru, Roberto ^a   Molla, Gianluca ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Cancer therapy; Cell death; Hydrogen peroxide; Kinetics; Oxygen reactivity

Indexed keywords

DEXTRO AMINO ACID OXIDASE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ALANINE; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; D-AMINO-ACID OXIDASE; DRUG SCREENING ASSAYS, ANTITUMOR; FUNGAL PROTEINS; HUMANS; HYDROGEN PEROXIDE; KINETICS; MICE; MODELS, MOLECULAR; MUTATION; OXYGEN; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 68849129382     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07191.x     Document Type: Article

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