Intermediate filament transcription in astrocytes is repressed by proteasome inhibition

FASEB Journal

Volumn 23, Issue 8, 2009, Pages 2710-2726

  Middeldorp, Jinte ^a   Kamphuis, Willem ^a   Sluijs, Jacqueline A ^a   Achoui, Dalila ^a   Leenaars, Cathalijn H C ^a   Feenstra, Matthijs G P ^a   Van Tijn, Paula ^a,e   Fischer, David F ^b   Berkers, Celia ^c   Ovaa, Huib ^c   Quinlan, Roy A ^d   Hol, Elly M ^a  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b BioFocus DPI   (United Kingdom)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d DURHAM UNIVERSITY   (United Kingdom)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Astrogliosis; Glial fibrillary acidic protein; Neurodegenerative diseases; Protein degradation

Indexed keywords

DIMETHYL SULFOXIDE; EPOXOMICIN; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERMEDIATE FILAMENT PROTEIN; LUCIFERASE; MESSENGER RNA; PROTEASOME; TRANSCRIPTION FACTOR; VIMENTIN; NERVE PROTEIN; NESTIN; OLIGOPEPTIDE; PROTEINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; ASTROCYTOSIS; BRAIN; BRAIN DISEASE; BRAIN INJURY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CELL LINE; CELL SURVIVAL; CYTOLOGY; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; HELA CELL; INTERMEDIATE FILAMENT; METABOLISM; PHYSIOLOGICAL STRESS; WISTAR RAT;

RATTUS;

ANIMALS; ASTROCYTES; BRAIN; CELL LINE; CELL SURVIVAL; DOWN-REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; HELA CELLS; HUMANS; INTERMEDIATE FILAMENT PROTEINS; INTERMEDIATE FILAMENTS; MALE; NERVE TISSUE PROTEINS; OLIGOPEPTIDES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, WISTAR; RNA, MESSENGER; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; VIMENTIN;

EID: 68849107085     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-127696     Document Type: Article

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