Endogenous and exogenous glucocorticoids prevent trimethyltin from causing neuronal degeneration of the mouse brain in vivo: Involvement of oxidative stress pathways

Journal of Pharmacological Sciences

Volumn 110, Issue 4, 2009, Pages 424-436

  Shuto, Makoto ^a,b   Higuchi, Kei ^a   Sugiyama, Chie ^a   Yoneyama, Masanori ^a   Kuramoto, Nobuyuki ^a   Nagashima, Reiko ^a   Kawada, Koichi ^a   Ogita, Kiyokazu ^a  

^a SETSUNAN UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Adrenalectomy; Dexamethasone; Neuronal degeneration; Oxidative stress; Trimethyltin

Indexed keywords

4 HYDROXYNONENAL; CALPAIN; CASPASE 3; DEXAMETHASONE; GLUCOCORTICOID; MIFEPRISTONE; STRESS ACTIVATED PROTEIN KINASE; TRIMETHYLTIN;

ADRENALECTOMY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN REGION; CELL DAMAGE; CONTROLLED STUDY; DENTATE GYRUS; DISEASE EXACERBATION; ENZYME ACTIVATION; IN VIVO STUDY; MALE; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; OLFACTORY BULB; OLFACTORY NUCLEUS; OXIDATIVE STRESS;

ADRENALECTOMY; ANIMALS; BRAIN; CALPAIN; CASPASE 3; DEXAMETHASONE; GLUCOCORTICOIDS; MALE; MICE; MIFEPRISTONE; NERVE DEGENERATION; NEUROTOXICITY SYNDROMES; OXIDATIVE STRESS; RABBITS; SIGNAL TRANSDUCTION; TRIMETHYLTIN COMPOUNDS;

EID: 68849103220     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.09107FP     Document Type: Article

References (35)

1. Bouldin TW, Goines ND, Bagnell RC, Krigman MR. Pathogenesis of trimethyltin neuronal toxicity. Ultrastructural and cytochemical observations. Am J Pathol. 1981;104:237-249.
2. Chang LW, Dyer RS. Early effects of trimethyltin on the dentate gyrus basket cells: a morphological study. J Toxicol Environ Health. 1985;16:641-653.
3. Oderfeld-Nowak B, Zaremba M. GM1 ganglioside potentiates trimethyltin-induced expression of interleukin-1 beta and the nerve growth factor in reactive astrocytes in the rat hippocampus: an immunocytochemical study. Neurochem Res. 1998;23:443-453. (Pubitemid 28109892)
4. Fiedorowicz A, Figiel I, Kaminska B, Zaremba M, Wilk S, Oderfeld-Nowak B. Dentate granule neuron apoptosis and glia activation in murine hippocampus induced by trimethyltin exposure. Brain Res. 2001;912:116-127. (Pubitemid 32800665)
5. Kawada K, Yoneyama M, Nagashima R, Ogita K. In vivo acute treatment with trimethyltin chloride causes neuronal degeneration in the murine olfactory bulb and anterior olfactory nucleus by different cascades in each region. J Neurosci Res. 2008;86:1635-1646.
6. Yoneyama M, Nishiyama N, Shuto M, Sugiyama C, Kawada K, Seko K, et al. In vivo depletion of endogenous glutathione facilitates trimethyltin-induced neuronal damage in the dentate gyrus of mice by enhancing oxidative stress. Neurochem Int. 2008;52:761-769.
7. Harry GJ, Sills R, Schlosser MJ, Maier WE. Neurodegeneration and glia response in rat hippocampus following nitro-L-arginine methyl ester (L-NAME). Neurotoxicol Res. 2001;3:307-319. (Pubitemid 32962893)
8. Viviani B, Corsini E, Pesenti M, Galli CL, Marinovich M. Trimethyltin- activated cyclooxygenase stimulates tumor necrosis factor-alpha release from glial cells through reactive oxygen species. Toxicol Appl Pharmacol. 2001;172:93-97. (Pubitemid 32373131)
9. Ogita K, Nitta Y, Watanabe Y, Nakatani Y, Nishiyama N, Sugiyama C, et al. In vivo activation of c-Jun N-terminal kinase signaling cascade prior to granule cell death induced by trimethyltin in the dentate gyrus of mice. Neuropharmacology. 2004;47:619-630.
10. Shuto M, Seko K, Kuramoto N, Sugiyama C, Kawada K, Yoneyama M, et al. Activation of c-Jun N-terminal kinase cascades is involved in part of the neuronal degeneration induced by trimethyltin in cortical neurons of mice. J Pharmacol Sci. 2008;109:60-70.
11. Geloso MC, Vercelli A, Corvino V, Repici M, Boca M, Haglid K, et al. Cyclooxygenase-2 and caspase-3 expression in trimethyltin-induced apoptosis in the mouse hippocampus. Exp Neurol. 2002;175:152-160. (Pubitemid 34507917)
12. Sapolsky RM. Glucocorticoid toxicity in the hippocampus: temporal aspects of neuronal vulnerability. Brain Research. 1985;359:300-305.
13. Conrad CD, McLaughlin KJ, Harman JS, Foltz C, Wieczorek L, Lightner E, et al. Chronic glucocorticoids increase hippocampal vulnerability to neurotoxicity under conditions that produce CA3 dendritic retraction but fail to impair spatial recognition memory. J Neurosci. 2007;27:8278-8285. (Pubitemid 47219614)
14. Imai H, Kabuto M, Takita M, Kato N. Interleukin-1 receptor antagonist inhibits transient increase of plasma corticosterone in the initial phase of trimethyltin-induced hippocampal necrosis. Neurotoxicology. 1998;19:163-166. (Pubitemid 28119876)
15. Tsutsumi S, Akaike M, Arimitsu H, Imai H, Kato N. Circulating corticosterone alters the rate of neuropathological and behavioral changes induced by trimethyltin in rats. Exp Neurol. 2002;173:86-94. (Pubitemid 34081728)
16. Imai H, Nishimura T, Sadamatsu M, Liu Y, Kabuto M, Kato N. Type II glucocorticoid receptors are involved in neuronal death and astrocyte activation induced by trimethyltin in the rat hippocampus. Exp Neurol. 2001;171:22-28. (Pubitemid 32848442)
17. Ogita K, Nishiyama N, Sugiyama C, Higuchi K, Yoneyama M, Yoneda Y. Regeneration of granule neurons after lesioning of hippocampal dentate gyrus: evaluation using adult mice treated with trimethyltin chloride as a model. J Neurosci Res. 2005;82:609-621. (Pubitemid 41740461)
18. Yoneyama M, Iwamoto N, Nagashima R, Sugiyama C, Kawada K, Kuramoto N, et al. Altered expression of heat shock protein 110 family members in mouse hippocampal neurons following trimethyltin treatment in vivo and in vitro. Neuropharmacology. 2008;55:693-703.
19. Nagai T, Yamada K, Kim HC, Kim YS, Noda Y, Imura A, et al. Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress. FASEB J. 2002;17:50-52.
20. Tang Y-P, Shimizu E, Dube GR, Rampon D, Kerchner FA, Zhuo M, et al. Genetic enhancement of learning and memory in mice. Nature. 1999;401:63-69. (Pubitemid 29418442)
21. Ogita K, Okuda H, Yamamoto Y, Nishiyama N, Yoneda Y. In vivo neuroprotective role of NMDA receptors against kainate-induced excitotoxicity in murine hippocampal pyramidal neurons. J Neurochem. 2003;85:1336-1346.
22. Yoneyama M, Seko K, Kawada K, Sugiyama C, Ogita K. High susceptibility of cortical neural progenitor cells to trimethyltin toxicity: involvement of both caspases and calpain in cell death. Neurochem Int. in press.
23. Wang KW. Calpain and caspase: can you tell the difference? Trends Neurosci. 2000;23:20-26.
24. Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell. 2000;103:239-252.
25. Shin EJ, Suh SK, Lim YK, Jhoo WK, Hjelle OP, Ottersen OP, et al. Ascorbate attenuates trimethyltin-induced oxidative burden and neuronal degeneration in the rat hippocampus by maintaining glutathione homeostasis. Neuroscience. 2005;133:715-727.
26. Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med. 1991;11:81-128. (Pubitemid 121003917)
27. Zarkovic K. 4-Hydroxynonenal and neurodegenerative diseases. Mol Aspects Med. 2003;24:293-303.
28. Herman JP, Patel PD, Akil H, Watson SJ. Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat. Mol Endocrinol. 1989;3:1886-1894. (Pubitemid 20003675)
29. De Kloet ER. Brain corticosteroid receptor balance and homeostatic control. Front Neuroendocrinol. 1991;12:95-164.
30. McEwen BS, Sapolsky RM. Stress and cognitive function. Curr Opin Neurobiol. 1995;5:205-216.
31. Sloviter RS, Valiquette G, Abrams GM, Ronk E, Sollas A, Paul LA, et al. Selective loss of hippocampal granule cells in the mature rat brain after adrenalectomy. Science. 1989;243:535-538. (Pubitemid 19048754)
32. Schmidt AJ, Krieg JC, Vedder H. Differential effects of glucocorticoids and gonadal steroids on glutathione levels in neuronal and glial cell systems. J Neurosci Res. 2002;67:544-550. (Pubitemid 34117124)
33. Kutuk O, Basaga H. Apoptosis signalling by 4-hydroxynonenal: a role for JNK-c-Jun/AP-1 pathway. Redox Rep. 2007;12:30-34. (Pubitemid 46210351)
34. Rabacchi SA, Friedman WJ, Shelanski ML, Troy CM. Divergence of the apoptotic pathways induced by 4-hydroxynonenal and amyloid beta-protein. Neurobiol Aging. 2004;25:1057-1066.
35. Peng ZF, Koh CH, Li QT, Manikandan J, Melendez AJ, Tang SY, et al. Deciphering the mechanism of HNE-induced apoptosis in cultured murine cortical neurons: transcriptional responses and cellular pathways. Neuropharmacology. 2007;53:687-698. (Pubitemid 47513174)