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Volumn 4, Issue 3, 2009, Pages 317-327

4-aminopyridine improves spatial memory in a murine model of HIV-1 encephalitis

Author keywords

4 aminopyridine; EPSP; Hippocampal slice; HIV 1 encephalitis; Learning and memory; Voltage gated K+ channels

Indexed keywords

4 AMINOPYRIDINE;

EID: 68749108090     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-009-9161-7     Document Type: Article
Times cited : (20)

References (61)
  • 2
    • 0037426575 scopus 로고    scopus 로고
    • Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis
    • DOI 10.1016/S0306-4522(02)00925-9
    • ER Anderson J Boyle WE Zink Y Persidsky HE Gendelman H Xiong 2003 Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis Neuroscience 118 359 369 10.1016/S0306-4522(02)00925-9 (Pubitemid 36423251)
    • (2003) Neuroscience , vol.118 , Issue.2 , pp. 359-369
    • Anderson, E.R.1    Boyle, J.2    Zink, W.E.3    Persidsky, Y.4    Gendelman, H.E.5    Xiong, H.6
  • 3
    • 4143125610 scopus 로고    scopus 로고
    • Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis
    • DOI 10.1523/JNEUROSCI.1933-04.2004
    • ER Anderson HE Gendelman H Xiong 2004 Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis J Neurosci 24 7194 7198 10.1523/JNEUROSCI.1933-04.2004 (Pubitemid 39096385)
    • (2004) Journal of Neuroscience , vol.24 , Issue.32 , pp. 7194-7198
    • Anderson, E.R.1    Gendelman, H.E.2    Xiong, H.3
  • 7
    • 0028332038 scopus 로고
    • The current status of studies of aminopyridines in patients with multiple sclerosis
    • DOI 10.1002/ana.410360728
    • CT Bever Jr 1994 The current status of studies of aminopyridines in patients with multiple sclerosis Ann Neurol 36 Suppl S118 S121 10.1002/ana.410360728 (Pubitemid 24220857)
    • (1994) Annals of Neurology , vol.36 , Issue.SUPPL.
    • Bever Jr., C.T.1
  • 9
    • 0035863725 scopus 로고    scopus 로고
    • New insights into endotoxin-induced activation of macrophages: Involvement of a K+ channel in transmembrane signaling
    • R Blunck O Scheel M Muller K Brandenburg U Seitzer U Seydel 2001 New insights into endotoxin-induced activation of macrophages: involvement of a K+ channel in transmembrane signaling J Immunol 166 1009 1015
    • (2001) J Immunol , vol.166 , pp. 1009-1015
    • Blunck, R.1    Scheel, O.2    Muller, M.3    Brandenburg, K.4    Seitzer, U.5    Seydel, U.6
  • 11
    • 0025253455 scopus 로고
    • Orally administered 4-aminopyridine improves clinical signs in multiple sclerosis
    • 10.1002/ana.410270215
    • FA Davis D Stefoski J Rush 1990 Orally administered 4-aminopyridine improves clinical signs in multiple sclerosis Ann Neurol 27 186 192 10.1002/ana.410270215
    • (1990) Ann Neurol , vol.27 , pp. 186-192
    • Davis, F.A.1    Stefoski, D.2    Rush, J.3
  • 13
    • 0032895217 scopus 로고    scopus 로고
    • Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center
    • IP Everall RK Heaton TD Marcotte RJ Ellis JA McCutchan JH Atkinson I Grant M Mallory E Masliah 1999 Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center Brain Pathol 9 209 217
    • (1999) Brain Pathol , vol.9 , pp. 209-217
    • Everall, I.P.1    Heaton, R.K.2    Marcotte, T.D.3    Ellis, R.J.4    Atkinson, J.H.5    Grant, I.6    Mallory, M.7    Masliah, E.8
  • 14
    • 0030660352 scopus 로고    scopus 로고
    • Neurodegeneration of somatostatin-immunoreactive neurons in HIV encephalitis
    • 10.1097/00005072-199704000-00004
    • L Fox M Alford C Achim M Mallory E Masliah 1997 Neurodegeneration of somatostatin-immunoreactive neurons in HIV encephalitis J Neuropathol Exp Neurol 56 360 368 10.1097/00005072-199704000-00004
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 360-368
    • Fox, L.1    Alford, M.2    Achim, C.3    Mallory, M.4    Masliah, E.5
  • 15
    • 0025884390 scopus 로고
    • Ion channels in leukocytes
    • EK Gallin 1991 Ion channels in leukocytes Physiol Rev 71 775 811
    • (1991) Physiol Rev , vol.71 , pp. 775-811
    • Gallin, E.K.1
  • 19
    • 0031887635 scopus 로고    scopus 로고
    • Influence of potassium channel modulators on cognitive processes in mice
    • 10.1038/sj.bjp. 0701709
    • C Ghelardini N Galeotti A Bartolini 1998 Influence of potassium channel modulators on cognitive processes in mice Br J Pharmacol 123 1079 1084 10.1038/sj.bjp. 0701709
    • (1998) Br J Pharmacol , vol.123 , pp. 1079-1084
    • Ghelardini, C.1    Galeotti, N.2    Bartolini, A.3
  • 20
    • 0032456841 scopus 로고    scopus 로고
    • Reduced K+ channel inactivation, spike broadening, and after-hyperpolarization in Kvbeta1.1-deficient mice with impaired learning
    • KP Giese JF Storm D Reuter NB Fedorov LR Shao T Leicher O Pongs AJ Silva 1998 Reduced K+ channel inactivation, spike broadening, and after- hyperpolarization in Kvbeta1.1-deficient mice with impaired learning Learn Mem 5 257 273
    • (1998) Learn Mem , vol.5 , pp. 257-273
    • Giese, K.P.1    Storm, J.F.2    Reuter, D.3    Fedorov, N.B.4    Shao, L.R.5    Leicher, T.6    Pongs, O.7    Silva, A.J.8
  • 21
    • 0034821027 scopus 로고    scopus 로고
    • Modulation of excitability as a learning and memory mechanism: A molecular genetic perspective
    • DOI 10.1016/S0031-9384(01)00517-0, PII S0031938401005170
    • KP Giese M Peters J Vernon 2001 Modulation of excitability as a learning and memory mechanism: a molecular genetic perspective Physiol Behav 73 803 810 10.1016/S0031-9384(01)00517-0 (Pubitemid 32885568)
    • (2001) Physiology and Behavior , vol.73 , Issue.5 , pp. 803-810
    • Giese, K.P.1    Peters, M.2    Vernon, J.3
  • 22
    • 0027436791 scopus 로고
    • Clinical neuropathologic correlation in HIV-associated dementia
    • JD Glass SL Wesselingh OA Selnes JC McArthur 1993 Clinical neuropathologic correlation in HIV-associated dementia Neurology 43 2230 2237
    • (1993) Neurology , vol.43 , pp. 2230-2237
    • Glass, J.D.1    Wesselingh, S.L.2    Selnes, O.A.3
  • 23
    • 0028808135 scopus 로고
    • Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia
    • 10.1002/ana.410380510
    • JD Glass H Fedor SL Wesselingh JC McArthur 1995 Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia Ann Neurol 38 755 762 10.1002/ana.410380510
    • (1995) Ann Neurol , vol.38 , pp. 755-762
    • Glass, J.D.1    Fedor, H.2    Wesselingh, S.L.3
  • 25
    • 0027069591 scopus 로고
    • Membrane potential modulates release of tumor necrosis factor in lipopolysaccharide-stimulated mouse macrophages
    • A Haslberger C Romanin R Koerber 1992 Membrane potential modulates release of tumor necrosis factor in lipopolysaccharide-stimulated mouse macrophages Mol Biol Cell 3 451 460
    • (1992) Mol Biol Cell , vol.3 , pp. 451-460
    • Haslberger, A.1    Romanin, C.2    Koerber, R.3
  • 26
    • 68749121632 scopus 로고    scopus 로고
    • Macrophage activates delayed-rectifier type K+ channels in cultured rat hippocampal neurons
    • Nov 3 to 7, San Diego, California
    • Hu D, Liu J, Xiong H (2007) Macrophage activates delayed-rectifier type K+ channels in cultured rat hippocampal neurons. The 37th Annual Meeting of the Society for Neuroscience, Nov 3 to 7, San Diego, California
    • (2007) The 37th Annual Meeting of the Society for Neuroscience
    • Hu, D.1    Liu, J.2    Xiong, H.3
  • 27
    • 34547655633 scopus 로고    scopus 로고
    • Voltage-gated potassium channel modulation of neurotoxic activity in human immunodeficiency virus type-1(HIV-1)-infected macrophages
    • 10.1007/s11481-007-9072-4
    • E Irvine J Keblesh J Liu H Xiong 2007 Voltage-gated potassium channel modulation of neurotoxic activity in human immunodeficiency virus type-1(HIV-1)-infected macrophages J Neuroimmune Pharmacol 2 265 269 10.1007/s11481-007-9072-4
    • (2007) J Neuroimmune Pharmacol , vol.2 , pp. 265-269
    • Irvine, E.1    Keblesh, J.2    Liu, J.3    Xiong, H.4
  • 28
    • 0037246672 scopus 로고    scopus 로고
    • Assessing the efficacy of highly active antiretroviral therapy in the brain
    • A Kandanearatchi B Williams IP Everall 2003 Assessing the efficacy of highly active antiretroviral therapy in the brain Brain Pathol 13 104 110
    • (2003) Brain Pathol , vol.13 , pp. 104-110
    • Kandanearatchi, A.1    Williams, B.2    Everall, I.P.3
  • 29
    • 0035912198 scopus 로고    scopus 로고
    • Pathways to neuronal injury and apoptosis in HIV-associated dementia
    • DOI 10.1038/35073667
    • M Kaul GA Garden SA Lipton 2001 Pathways to neuronal injury and apoptosis in HIV-associated dementia Nature 410 988 994 10.1038/35073667 (Pubitemid 32335850)
    • (2001) Nature , vol.410 , Issue.6831 , pp. 988-994
    • Kaul, M.1    Garden, G.A.2    Lipton, S.A.3
  • 30
    • 0344406085 scopus 로고    scopus 로고
    • Changing patterns in the neuropathogenesis of HIV during the HAART era
    • TD Langford SL Letendre GJ Larrea E Masliah 2003 Changing patterns in the neuropathogenesis of HIV during the HAART era Brain Pathol 13 195 210
    • (2003) Brain Pathol , vol.13 , pp. 195-210
    • Langford, T.D.1    Letendre, S.L.2    Larrea, G.J.3    Masliah, E.4
  • 31
    • 0027511788 scopus 로고
    • Quantal analysis and synaptic anatomy - Integrating two views of hippocampal plasticity
    • DOI 10.1016/0166-2236(93)90122-3
    • JE Lisman KM Harris 1993 Quantal analysis and synaptic anatomy-integrating two views of hippocampal plasticity Trends Neurosci 16 141 147 10.1016/0166-2236(93)90122-3 (Pubitemid 23085470)
    • (1993) Trends in Neurosciences , vol.16 , Issue.4 , pp. 141-147
    • Lisman, J.E.1    Harris, K.M.2
  • 33
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: An embarrassment of riches
    • DOI 10.1016/j.neuron.2004.09.012, PII S0896627304006087
    • RC Malenka MF Bear 2004 LTP and LTD: an embarrassment of riches Neuron 44 5 21 10.1016/j.neuron.2004.09.012 (Pubitemid 39348827)
    • (2004) Neuron , vol.44 , Issue.1 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 35
    • 0026475876 scopus 로고
    • Selective neuronal vulnerability in HIV encephalitis
    • 10.1097/00005072-199211000-00003
    • E Masliah N Ge C Achim L Hansen C Wiley 1992 Selective neuronal vulnerability in HIV encephalitis J Neuropathol Exp Neurol 51 585 593 10.1097/00005072-199211000-00003
    • (1992) J Neuropathol Exp Neurol , vol.51 , pp. 585-593
    • Masliah, E.1    Ge, N.2    Achim, C.3    Hansen, L.4    Wiley, C.5
  • 37
    • 0038475861 scopus 로고    scopus 로고
    • Human immunodeficiency virus-associated dementia: An evolving disease
    • 10.1080/713831484
    • JC McArthur N Haughey S Gartner K Conant C Pardo A Nath N Sacktor 2003 Human immunodeficiency virus-associated dementia: an evolving disease J Neurovirol 9 205 221 10.1080/713831484
    • (2003) J Neurovirol , vol.9 , pp. 205-221
    • Haughey, N.1    Gartner, S.2    Conant, K.3    Pardo, C.4    Nath, A.5    Sacktor, N.6
  • 38
    • 23744505999 scopus 로고    scopus 로고
    • Neurological complications of HIV infection
    • DOI 10.1016/S1474-4422(05)70165-4, PII S1474442205701654
    • JC McArthur BJ Brew A Nath 2005 Neurological complications of HIV infection Lancet Neurol 4 543 555 10.1016/S1474-4422(05)70165-4 (Pubitemid 41139976)
    • (2005) Lancet Neurology , vol.4 , Issue.9 , pp. 543-555
    • McArthur, J.C.1    Brew, B.J.2    Nath, A.3
  • 39
    • 34248512907 scopus 로고    scopus 로고
    • HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients
    • DOI 10.1097/QAD.0b013e3280ef6acd, PII 0000203020070531000004
    • JA McCutchan JW Wu K Robertson SL Koletar RJ Ellis S Cohn M Taylor S Woods R Heaton J Currier PL Williams 2007 HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients AIDS 21 1109 1117 10.1097/QAD.0b013e3280ef6acd (Pubitemid 46763281)
    • (2007) AIDS , vol.21 , Issue.9 , pp. 1109-1117
    • McCutchan, J.A.1    Wu, J.W.2    Robertson, K.3    Koletar, S.L.4    Ellis, R.J.5    Cohn, S.6    Taylor, M.7    Woods, S.8    Heaton, R.9    Currier, J.10    Williams, P.L.11
  • 40
    • 0025855788 scopus 로고
    • Effect of apamin, a toxin that inhibits Ca(2+)-dependent K+ channels, on learning and memory processes
    • 10.1016/0006-8993(91)90950-Z
    • C Messier C Mourre B Bontempi J Sif M Lazdunski C Destrade 1991 Effect of apamin, a toxin that inhibits Ca(2+)-dependent K+ channels, on learning and memory processes Brain Res 551 322 326 10.1016/0006-8993(91)90950-Z
    • (1991) Brain Res , vol.551 , pp. 322-326
    • Messier, C.1    Mourre, C.2    Bontempi, B.3    Sif, J.4    Lazdunski, M.5    Destrade, C.6
  • 41
    • 0032880444 scopus 로고    scopus 로고
    • Pathobiology of human immunodeficiency virus dementia
    • 10.1055/s-2008-1040830
    • A Nath 1999 Pathobiology of human immunodeficiency virus dementia Semin Neurol 19 113 127 10.1055/s-2008-1040830
    • (1999) Semin Neurol , vol.19 , pp. 113-127
    • Nath, A.1
  • 44
    • 0030838827 scopus 로고    scopus 로고
    • Development of laboratory and animal model systems for HIV-1 encephalitis and its associated dementia
    • Y Persidsky HE Gendelman 1997 Development of laboratory and animal model systems for HIV-1 encephalitis and its associated dementia J Leukoc Biol 62 100 106
    • (1997) J Leukoc Biol , vol.62 , pp. 100-106
    • Persidsky, Y.1    Gendelman, H.E.2
  • 46
    • 0029065185 scopus 로고
    • Evidence of apoptotic cell death in HIV encephalitis
    • CK Petito B Roberts 1995 Evidence of apoptotic cell death in HIV encephalitis Am J Pathol 146 1121 1130
    • (1995) Am J Pathol , vol.146 , pp. 1121-1130
    • Petito, C.K.1    Roberts, B.2
  • 47
    • 0036378395 scopus 로고    scopus 로고
    • A potassium ion channel is involved in cytokine production by activated human macrophages
    • 10.1046/j.1365-2249.2002.01965.x
    • MR Qiu TJ Campbell SN Breit 2002 A potassium ion channel is involved in cytokine production by activated human macrophages Clin Exp Immunol 130 67 74 10.1046/j.1365-2249.2002.01965.x
    • (2002) Clin Exp Immunol , vol.130 , pp. 67-74
    • Qiu, M.R.1    Campbell, T.J.2    Breit, S.N.3
  • 49
    • 0346727499 scopus 로고    scopus 로고
    • Activation of K+ channels: An essential pathway in programmed cell death
    • 10.1152/ajplung.00041.2003
    • CV Remillard JX Yuan 2004 Activation of K+ channels: an essential pathway in programmed cell death Am J Physiol Lung Cell Mol Physiol 286 L49 L67 10.1152/ajplung.00041.2003
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286
    • Remillard, C.V.1    Yuan, J.X.2
  • 52
    • 0036948147 scopus 로고    scopus 로고
    • The epidemiology of human immunodeficiency virus-associated neurological disease in the era of highly active antiretroviral therapy
    • DOI 10.1080/13550280290101094
    • N Sacktor MP McDermott K Marder G Schifitto OA Selnes JC McArthur Y Stern S Albert D Palumbo K Kieburtz JA De Marcaida B Cohen L Epstein 2002 HIV-associated cognitive impairment before and after the advent of combination therapy J Neurovirol 8 136 142 10.1080/13550280290101094 (Pubitemid 36097787)
    • (2002) Journal of NeuroVirology , vol.8 , Issue.SUPPL. 2 , pp. 115-121
    • Sacktor, N.1
  • 53
    • 33747059622 scopus 로고    scopus 로고
    • Antiretroviral therapy improves cognitive impairment in HIV+ individuals in sub-Saharan Africa
    • DOI 10.1212/01.wnl.0000225183.74521.72, PII 0000611420060725000030
    • N Sacktor N Nakasujja R Skolasky K Robertson M Wong S Musisi A Ronald E Katabira 2006 Antiretroviral therapy improves cognitive impairment in HIV+ individuals in sub-Saharan Africa Neurology 67 311 314 10.1212/01.wnl. 0000225183.74521.72 (Pubitemid 44305421)
    • (2006) Neurology , vol.67 , Issue.2 , pp. 311-314
    • Sacktor, N.1    Nakasujja, N.2    Skolasky, R.3    Robertson, K.4    Wong, M.5    Musisi, S.6    Ronald, A.7    Katabira, E.8
  • 54
    • 37349048549 scopus 로고    scopus 로고
    • Cognitive dysfunction in HIV encephalitic SCID mice correlates with levels of Interferon-α in the brain
    • DOI 10.1097/QAD.0b013e3282f08c2f, PII 0000203020071018000004
    • AR Sas HA Bimonte-Nelson WR Tyor 2007 Cognitive dysfunction in HIV encephalitic SCID mice correlates with levels of interferon-alpha in the brain AIDS 21 2151 2159 10.1097/QAD.0b013e3282f08c2f (Pubitemid 350287212)
    • (2007) AIDS , vol.21 , Issue.16 , pp. 2151-2159
    • Sas, A.R.1    Bimonte-Nelson, H.A.2    Tyor, W.R.3
  • 56
    • 0023134727 scopus 로고
    • 4-Aminopyridine improves clinical signs in multiple sclerosis
    • DOI 10.1002/ana.410210113
    • D Stefoski FA Davis M Faut CL Schauf 1987 4-Aminopyridine improves clinical signs in multiple sclerosis Ann Neurol 21 71 77 10.1002/ana.410210113 (Pubitemid 17004147)
    • (1987) Annals of Neurology , vol.21 , Issue.1 , pp. 71-77
    • Stefoski, D.1    Davis, F.A.2    Faut, M.3    Schauf, C.L.4
  • 59
    • 0028024080 scopus 로고
    • Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome
    • DOI 10.1002/ana.410360422
    • CA Wiley C Achim 1994 Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome Ann Neurol 36 673 676 10.1002/ana.410360422 published erratum appears in Ann Neurol 1995 Jan;37(1):140 (Pubitemid 24309385)
    • (1994) Annals of Neurology , vol.36 , Issue.4 , pp. 673-676
    • Wiley, C.A.1    Achim, C.2
  • 60
    • 0032905090 scopus 로고    scopus 로고
    • Unraveling the mechanisms of neurotoxicity in HIV type 1-associated dementia: Inhibition of neuronal synaptic transmission by macrophage secretory products
    • DOI 10.1089/088922299311718
    • H Xiong J Zheng M Thylin HE Gendelman 1999 Unraveling the mechanisms of neurotoxicity in HIV type 1-associated dementia: inhibition of neuronal synaptic transmission by macrophage secretory products AIDS Res Hum Retroviruses 15 57 63 10.1089/088922299311718 (Pubitemid 29038325)
    • (1999) AIDS Research and Human Retroviruses , vol.15 , Issue.1 , pp. 57-63
    • Xiong, H.1    Zheng, J.2    Thylin, M.3    Gendelman, H.E.4
  • 61
    • 0141852939 scopus 로고    scopus 로고
    • Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses
    • DOI 10.1016/S0896-6273(03)00543-9
    • SS Zakharenko SL Patterson I Dragatsis SO Zeitlin SA Siegelbaum ER Kandel A Morozov 2003 Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses Neuron 39 975 990 10.1016/S0896-6273(03)00543-9 (Pubitemid 37130213)
    • (2003) Neuron , vol.39 , Issue.6 , pp. 975-990
    • Zakharenko, S.S.1    Patterson, S.L.2    Dragatsis, I.3    Zeitlin, S.O.4    Siegelbaum, S.A.5    Kandel, E.R.6    Morozov, A.7


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