Antiretroviral therapy improves cognitive impairment in HIV+ individuals in sub-Saharan Africa

Neurology

Volumn 67, Issue 2, 2006, Pages 311-314

  Sacktor, N ^a,f   Nakasujja, N ^b   Skolasky, R ^a   Robertson, K ^c   Wong, M ^d   Musisi, S ^b   Ronald, A ^e   Katabira, E ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MAKERERE UNIVERSITY   (Uganda)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF VIRGINIA   (United States)

^e UNIVERSITY OF MANITOBA   (Canada)

^f JOHNS HOPKINS BAYVIEW MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; LAMIVUDINE; NEVIRAPINE; STAVUDINE; TENOFOVIR; ZIDOVUDINE;

ADULT; AFRICA; ANAMNESIS; ARTICLE; CD4 LYMPHOCYTE COUNT; CLINICAL ARTICLE; COGNITIVE DEFECT; DEMENTIA; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; FOLLOW UP; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KARNOFSKY PERFORMANCE STATUS; MALE; MENTAL PERFORMANCE; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; PSYCHOLOGIC TEST; PSYCHOMOTOR DEVELOPMENT; RATING SCALE; RESOURCE ALLOCATION; SCORING SYSTEM; UGANDA; VERBAL MEMORY; AFRICA SOUTH OF THE SAHARA; COMORBIDITY; METHODOLOGY; PREVALENCE; RISK ASSESSMENT; RISK FACTOR; STATISTICS; TREATMENT OUTCOME;

ADULT; AFRICA SOUTH OF THE SAHARA; ANTI-RETROVIRAL AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; COGNITION DISORDERS; COMORBIDITY; FEMALE; HIV INFECTIONS; HUMANS; MALE; PREVALENCE; RISK ASSESSMENT; RISK FACTORS; TREATMENT OUTCOME;

EID: 33747059622     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000225183.74521.72     Document Type: Article

References (17)

1. Sacktor N. The epidemiology of human immunodeficiency virus-associated neurological disease in the era of highly active antiretroviral therapy. J Neurovirol 2002;8(suppl 2):115-121.
2. Sacktor N, Skolasky RL, Lyles RH, et al. Improvement in HIV-associated motor slowing after antiretroviral therapy including protease inhibitors. J Neurovirol 2000;6:84-88.
3. Sacktor NC, Lyles RH, Skolasky RL, et al. Combination antiretroviral therapy including protease inhibitors improves HIV-associated cognitive impairment. Neurology 1999;52:1640-1647.
4. Robertson KR, Robertson WT, Ford S, et al. Highly active antiretroviral therapy improves neurocognitive functioning. J AIDS 2004;36:562-566.
5. Brodt HR, Kamps BS, Gute P, et al. Changing incidence of AIDS-defining illnesses in the era of antiretroviral combination therapy. AIDS 1997;11:1731-1738.
6. Sacktor N, Lyles RH, Skolasky R, et al. HIV-associated neurologic disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998. Neurology 2001;56:257-260.
7. Joint United Nations Program on HIV/AIDS.UN/AIDS and the World Health Organization. AIDS Epidemic Update, Dec. 2003.
8. Wong M, Robertson R, Nakasujja N, et al. HIV-associated neurological complications among HIV-seropositive individuals in Uganda. Neurology 2004;62:A444.
9. Quinn TC. The Academic Alliance for AIDS Care and Prevention in Africa. Hopkins HIV Report 2001;13:1-4.
10. Sacktor NC, Wong M, Nakasujja N, et al. The International HIV Dementia Scale: a new rapid screening test for HIV dementia. AIDS 2005;19:1367-1374.
11. Karnofsky DA, Abelman WH, Craver LF, et al. The use of nitrogen mustards in the palliative treatment of carcinoma. Cancer 1948;1:634-656.
12. Maj M, Satz P, Janssen R, et al. WHO Neuropsychiatric AIDS Study, cross-sectional Phase II. Neuropsychological and neurological findings. Arch Gen Psychiatry 1994;51:51-61.
13. Smith A. Symbol Digit Modalities test. Western Psychological Service 1982.
14. Zeger SL, Liang KY, Albert PS. Models for longitudinal data: a generalized estimating equation approach. Biometrics 1988;44:1049-1060.
15. Oyugi JH, Byakika-Tusiime J, Charlebois ED, et al. Multiple validated measures of adherence indicate high levels of adherence to generic HIV antiretroviral therapy in a resource-limited setting. J AIDS 2004;36:1100-1102.
16. Byanyima KR. Cranial CT findings in the HIV-1 infected patients with CNS symptoms at Mulago hospital. M Med dissertation. B99C Albert Cook Library Makerere University, 1998.
17. Wamala D. Brain infections in acquired immune deficiency syndrome due to human immune deficiency virus in Mulago Hospital. An autopsy study M Med dissertation. W18 Albert Cook Library Makerere University, 1998.