Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus

BMC Medical Genomics

Volumn 2, Issue , 2009, Pages

  Hu, Yaomin ^a   Kaisaki, Pamela J ^a   Argoud, Karène ^a   Wilder, Steven P ^a   Wallace, Karin J ^a   Woon, Peng Y ^a   Blancher, Christine ^a   Tarnow, Lise ^b   Groop, Per Henrik ^c   Hadjadj, Samy ^d   Marre, Michel ^e   Parving, Hans Henrik ^f   Farrall, Martin ^a   Cox, Roger D ^g   Lathrop, Mark ^h   Vionnet, Nathalie ⁱ   Bihoreau, Marie Thérèse ^a   Gauguier, Dominique ^a,j  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b STENO DIABETES CENTER   (Denmark)

^c UNIVERSITY OF HELSINKI   (Finland)

^d POITIERS UNIVERSITY HOSPITAL   (France)

^e BICHAT HOSPITAL   (France)

^f University of Copenhagen   (Denmark)

^g MRC Radiation/Genome Stability Unit   (United Kingdom)

^h CENTRE NATIONAL DE GÉNOTYPAGE   (France)

ⁱ INSERM   (France)

^j CENTRE DE RECHERCHE DES CORDELIERS   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; GENE EXPRESSION PROFILING; GENE LOCUS; GENETIC SUSCEPTIBILITY; GOTO KAKIZAKI RAT; HYPERGLYCEMIA; INSULIN RESISTANCE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; WISTAR KYOTO RAT;

ANIMALIA; RATTUS;

EID: 68749084951     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/1755-8794-2-41     Document Type: Article

References (52)

1. New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology. G Wolf, Eur J Clin Invest 2004 34 12 785 796 10.1111/j.1365-2362.2004.01429.x 15606719 (Pubitemid 39657924)
2. Prediction, progression and prevention of diabetic nephropathy. The Minkowski Lecture 2005. P Rossing, Diabetologia 2006 49 1 11 19 10.1007/s00125-005-0077-3 16341685 (Pubitemid 43151607)
3. Clustering of long-term complications in families with diabetes in the diabetes control and complications trial. Group TDCaCTR, Diabetes 1997 46 11 1829 1839 10.2337/diabetes.46.11.1829 9356033 (Pubitemid 27456418)
4. Genetics of diabetic nephropathy: evidence for major and minor gene effects. AS Krolewski, Kidney Int 1999 55 4 1582 1596 10.1046/j.1523-1755.1999. 00371.x 10201028 (Pubitemid 29157162)
5. Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy. ER Seaquist FC Goetz S Rich J Barbosa, N Engl J Med 1989 320 18 1161 1165 2710189 (Pubitemid 19124296)
6. Segregation analysis of diabetic nephropathy in Pima Indians. G Imperatore WC Knowler DJ Pettitt S Kobes PH Bennett RL Hanson, Diabetes 2000 49 6 1049 1056 10.2337/diabetes.49.6.1049 10866059 (Pubitemid 30349429)
7. Genetics of diabetic nephropathy. JD Rippin A Patel SC Bain, Best Pract Res Clin Endocrinol Metab 2001 15 3 345 358 10.1053/beem.2001.0150 11554775 (Pubitemid 32916266)
8. Major susceptibility locus for nephropathy in type 1 diabetes on chromosome 3q: results of novel discordant sib-pair analysis. DK Moczulski JJ Rogus A Antonellis JH Warram AS Krolewski, Diabetes 1998 47 7 1164 1169 10.2337/diabetes.47.7.1164 9648845 (Pubitemid 28294564)
9. Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy. DW Bowden M Sale TD Howard A Qadri BJ Spray CB Rothschild G Akots SS Rich BI Freedman, Diabetes 1997 46 5 882 886 10.2337/diabetes.46.5.882 9133559 (Pubitemid 27188268)
10. Sib-pair linkage analysis for susceptibility genes for microvascular complications among Pima Indians with type 2 diabetes. Pima Diabetes Genes Group. G Imperatore RL Hanson DJ Pettitt S Kobes PH Bennett WC Knowler, Diabetes 1998 47 5 821 830 10.2337/diabetes.47.5.821 9588456 (Pubitemid 28201814)
11. Gene for susceptibility to diabetic nephropathy in type 2 diabetes maps to 18q22.3-23. I Vardarli LJ Baier RL Hanson I Akkoyun C Fischer P Rohmeiss A Basci CR Bartram FJ Van Der Woude B Janssen, Kidney Int 2002 62 6 2176 2183 10.1046/j.1523-1755.2002.00663.x 12427143 (Pubitemid 35366173)
12. Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). SK Iyengar HE Abboud KA Goddard MF Saad SG Adler NH Arar DW Bowden R Duggirala RC Elston RL Hanson, Diabetes 2007 56 6 1577 1585 10.2337/db06-1154 17363742 (Pubitemid 46842614)
13. Assessment of 115 candidate genes for diabetic nephropathy by transmission/disequilibrium test. KG Ewens RA George K Sharma FN Ziyadeh RS Spielman, Diabetes 2005 54 11 3305 3318 10.2337/diabetes.54.11.3305 16249459 (Pubitemid 43336530)
14. The functional landscape of mouse gene expression. W Zhang QD Morris R Chang O Shai MA Bakowski N Mitsakakis N Mohammad MD Robinson R Zirngibl E Somogyi, J Biol 2004 3 5 21 15588312 10.1186/jbiol16 (Pubitemid 46424438)
15. Transcriptome analysis and kidney research: toward systems biology. M Liang AW Cowley Jr MJ Hessner J Lazar DP Basile JL Pietrusz, Kidney Int 2005 67 6 2114 2122 10.1111/j.1523-1755.2005.00315.x 15882254 (Pubitemid 41623373)
16. Global analysis of gene expression in mammalian kidney. O Soutourina L Cheval A Doucet, Pflugers Arch 2005 450 1 13 25 10.1007/s00424-004-1368-0 15611884 (Pubitemid 40558528)
17. Genomic strategies for diabetic nephropathy. K Susztak K Sharma M Schiffer P McCue E Ciccone EP Bottinger, J Am Soc Nephrol 2003 14 8 Suppl 3 S271 278 10.1097/01.ASN.0000078035.81397.8A 12874445 (Pubitemid 36903939)
18. Rodent models of nephropathy associated with type II diabetes. U Janssen AO Phillips J Floege, J Nephrol 1999 12 3 159 172 10440513 (Pubitemid 29370823)
19. Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. D Gauguier P Froguel V Parent C Bernard MT Bihoreau B Portha MR James L Penicaud M Lathrop A Ktorza, Nat Genet 1996 12 1 38 43 10.1038/ng0196-38 8528248 (Pubitemid 26011317)
20. Association of prolonged hyperglycemia with glomerular hypertrophy and renal basement membrane thickening in the Goto Kakizaki model of non-insulin-dependent diabetes mellitus. AO Phillips K Baboolal S Riley H Grone U Janssen R Steadman J Williams J Floege, Am J Kidney Dis 2001 37 2 400 410 10.1053/ajkd.2001.21322 11157383 (Pubitemid 32116034)
21. Late onset of diabetic nephropathy in spontaneously diabetic GK rats. N Sato K Komatsu H Kurumatani, Am J Nephrol 2003 23 5 334 342 10.1159/000072915 12920324 (Pubitemid 37116933)
22. Impact of genetic background on nephropathy in diabetic mice. SB Gurley SE Clare KP Snow A Hu TW Meyer TM Coffman, Am J Physiol Renal Physiol 2006 290 1 F214 222 10.1152/ajprenal.00204.2005 16118394
23. Rodent models of streptozotocin-induced diabetic nephropathy. GH Tesch TJ Allen, Nephrology 2007 12 3 261 266 10.1111/j.1440-1797.2007.00796.x 17498121 (Pubitemid 46718209)
24. Comparative analysis of methods for gene transcription profiling data derived from different microarray technologies in rat and mouse models of diabetes. SP Wilder PJ Kaisaki K Argoud J Ragoussis MT Bihoreau D Gauguier, BMC Genomics 2009 10 63 19196459 10.1186/1471-2164-10-63
25. Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice. AA Toye ME Dumas C Blancher AR Rothwell JF Fearnside SP Wilder MT Bihoreau O Cloarec I Azzouzi S Young, Diabetologia 2007 50 9 1867 1879 10.1007/s00125-007-0738-5 17618414 (Pubitemid 47222857)
26. From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines. BF Schrijvers AS De Vriese A Flyvbjerg, Endocr Rev 2004 25 6 971 1010 10.1210/er.2003-0018 15583025 (Pubitemid 39657775)
27. Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1. B Janssen D Hohenadel P Brinkkoetter V Peters N Rind C Fischer I Rychlik M Cerna M Romzova E de Heer, Diabetes 2005 54 8 2320 2327 10.2337/diabetes.54.8.2320 16046297 (Pubitemid 41134258)
28. Analysis of 14 candidate genes for diabetic nephropathy on chromosome 3q in European populations: strongest evidence for association with a variant in the promoter region of the adiponectin gene. N Vionnet D Tregouet G Kazeem I Gut PH Groop L Tarnow HH Parving S Hadjadj C Forsblom M Farrall, Diabetes 2006 55 11 3166 3174 10.2337/db06-0271 17065357 (Pubitemid 44923657)
29. Integration of the Rat Recombination and EST Maps in the Rat Genomic Sequence and Comparative Mapping Analysis With the Mouse Genome. SP Wilder MT Bihoreau K Argoud TK Watanabe M Lathrop D Gauguier, Genome Res 2004 14 4 758 765 15060020 10.1101/gr.2001604 (Pubitemid 38500250)
30. Progression of diabetic nephropathy. Insights from cell culture studies and animal models. AO Phillips U Janssen J Floege, Kidney Blood Press Res 1999 22 12 81 97 10.1159/000025912 10352411 (Pubitemid 29243450)
31. Molecular profiling of diabetic mouse kidney reveals novel genes linked to glomerular disease. K Susztak E Bottinger A Novetsky D Liang Y Zhu E Ciccone D Wu S Dunn P McCue K Sharma, Diabetes 2004 53 3 784 794 10.2337/diabetes.53.3. 784 14988265 (Pubitemid 38270650)
32. Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome. RH Wallis SC Collins PJ Kaisaki K Argoud SP Wilder KJ Wallace M Ria A Ktorza P Rorsman MT Bihoreau, PLoS ONE 2008 3 8 e2962 18698428 10.1371/journal.pone.0002962
33. Sequence polymorphisms cause many false cis eQTLs. R Alberts P Terpstra Y Li R Breitling JP Nap RC Jansen, PLoS ONE 2007 2 7 e622 17637838 10.1371/journal.pone.0000622 (Pubitemid 351279929)
34. Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats. JM Seubert F Xu JP Graves JB Collins SO Sieber RS Paules DL Kroetz DC Zeldin, Am J Physiol Renal Physiol 2005 289 3 F552 561 10.1152/ajprenal.00354.2004 15798089 (Pubitemid 41208470)
35. Initial characterization of a rat model of diabetic nephropathy. MA Nobrega S Fleming RJ Roman M Shiozawa N Schlick J Lazar HJ Jacob, Diabetes 2004 53 3 735 742 10.2337/diabetes.53.3.735 14988259 (Pubitemid 38270644)
36. Endothelial dysfunction and salt-sensitive hypertension in spontaneously diabetic Goto-Kakizaki rats. ZJ Cheng T Vaskonen I Tikkanen K Nurminen H Ruskoaho H Vapaatalo D Muller JK Park FC Luft EM Mervaala, Hypertension 2001 37 2 Part 2 433 439 11230314 (Pubitemid 32199007)
37. Animal models of diabetes mellitus. DA Rees JC Alcolado, Diabet Med 2005 22 4 359 370 10.1111/j.1464-5491.2005.01499.x 15787657 (Pubitemid 40516231)
38. Insulin resistance in insulin-dependent diabetic patients with microalbuminuria. J Yip MB Mattock A Morocutti M Sethi R Trevisan G Viberti, Lancet 1993 342 8876 883 887 10.1016/0140-6736(93)91943-G 8105164 (Pubitemid 23291590)
39. Tissue-specific transcriptome responses in rats with early streptozotocin-induced diabetes. KE Knoll JL Pietrusz M Liang, Physiol Genomics 2005 21 2 222 229 10.1152/physiolgenomics.00231.2004 15713786 (Pubitemid 40898482)
40. Gene expression profile in streptozotocin-induced diabetic mice kidneys undergoing glomerulosclerosis. J Wada H Zhang Y Tsuchiyama K Hiragushi K Hida K Shikata YS Kanwar H Makino, Kidney Int 2001 59 4 1363 1373 10.1046/j.1523-1755. 2001.0590041363.x 11260397 (Pubitemid 32281224)
41. Defining human diabetic nephropathy on the molecular level: integration of transcriptomic profiles with biological knowledge. S Martini F Eichinger V Nair M Kretzler, Rev Endocr Metab Disord 2008 9 4 267 274 10.1007/s11154-008- 9103-3 18704688
42. Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy. HJ Baelde M Eikmans PP Doran DW Lappin E de Heer JA Bruijn, Am J Kidney Dis 2004 43 4 636 650 10.1053/j.ajkd.2003.12.028 15042541 (Pubitemid 38401879)
43. Gremlin: an example of the re-emergence of developmental programmes in diabetic nephropathy. DW Lappin R McMahon M Murphy HR Brady, Nephrol Dial Transplant 2002 17 Suppl 9 65 67 10.1093/ndt/17.suppl-9.65 12386293
44. Trefoil factors: initiators of mucosal healing. D Taupin DK Podolsky, Nat Rev Mol Cell Biol 2003 4 9 721 732 10.1038/nrm1203 14506475 (Pubitemid 37082187)
45. The bone morphogenetic proteins (BMPs). Their role in renal fibrosis and renal function. S Klahr, J Nephrol 2003 16 2 179 185 12768064 (Pubitemid 37304073)
46. Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis. S Gupta MR Clarkson J Duggan HR Brady, Kidney Int 2000 58 4 1389 1399 10.1046/j.1523-1755.2000.00301.x 11012874 (Pubitemid 30739645)
47. Glutathione transferases. JD Hayes JU Flanagan IR Jowsey, Annu Rev Pharmacol Toxicol 2005 45 51 88 10.1146/annurev.pharmtox.45.120403.095857 15822171 (Pubitemid 40261798)
48. Genomic organization of the mammalian SLC14a2 urea transporter genes. CP Smith RA Fenton, J Membr Biol 2006 212 2 109 117 10.1007/s00232-006-0870-z 17264986 (Pubitemid 46292326)
49. Disease-associated mutations affect intracellular traffic and paracellular Mg2+ transport function of Claudin-16. PJ Kausalya S Amasheh D Gunzel H Wurps D Muller M Fromm W Hunziker, J Clin Invest 2006 116 4 878 891 16528408 10.1172/JCI26323
50. Transgenic RNAi depletion of claudin-16 and the renal handling of magnesium. J Hou Q Shan T Wang AS Gomes Q Yan DL Paul M Bleich DA Goodenough, J Biol Chem 2007 282 23 17114 17122 10.1074/jbc.M700632200 17442678 (Pubitemid 47093227)
51. Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy. DM Sadlier SB Connolly NE Kieran S Roxburgh DP Brazil L Kairaitis Y Wang DC Harris P Doran HR Brady, J Biol Chem 2004 279 28 29670 29680 10.1074/jbc.M313408200 15033991 (Pubitemid 38915850)
52. The Kruppel-like zinc-finger gene ZNF236 is alternatively spliced and excluded as susceptibility gene for diabetic nephropathy. N Halama A Yard-Breedijk I Vardarli I Akkoyun B Yard B Janssen FJ van der Woude, Genomics 2003 82 3 406 411 10.1016/S0888-7543(03)00120-4 12906866 (Pubitemid 36952312)