Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome

PLoS ONE

Volumn 3, Issue 8, 2008, Pages

  Wallis, Robert H ^a   Collins, Stephan C ^a,b   Kaisaki, Pamela J ^a   Argoud, Karène ^a   Wilder, Steven P ^a   Wallace, Karin J ^a   Ria, Massimiliano ^a   Ktorza, Alain ^c,d   Rorsman, Patrik ^b   Bihoreau, Marie Thérèse ^a   Gauguier, Dominique ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c CNRS   (France)

^d INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; ARGININE; GLUCOSE; LIPID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMETABOLIC SYNDROME; CHROMOSOME 1; CONGENIC STRAIN; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GENOTYPE; GOTO KAKIZAKI RAT; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERTENSION; HYPERTRIGLYCERIDEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; KIDNEY; LIVER; MALE; METABOLIC SYNDROME X; NONHUMAN; OBESITY; PANCREAS; PATHOGENESIS; PATHOPHYSIOLOGY; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; RAT; RODENT; SINGLE NUCLEOTIDE POLYMORPHISM; SKELETAL MUSCLE; WHITE ADIPOSE TISSUE; ANIMAL; BASAL METABOLIC RATE; BLOOD; BLOOD PRESSURE; BODY WEIGHT; CHROMOSOME MAP; DISEASE MODEL; GENETICS; GLUCOSE BLOOD LEVEL; HYPERINSULINISM; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; RAT STRAIN; SECRETION;

ANIMALIA; RATTUS; RODENTIA;

ANIMALS; ARGININE; BASAL METABOLISM; BLOOD GLUCOSE; BLOOD PRESSURE; BODY WEIGHT; CHROMOSOME MAPPING; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GLUCOSE; HYPERGLYCEMIA; HYPERINSULINISM; INSULIN; ISLETS OF LANGERHANS; LIPIDS; OBESITY; QUANTITATIVE TRAIT LOCI; RATS; RATS, INBRED STRAINS;

EID: 51849114275     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002962     Document Type: Article

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