Genome wide analysis of human genes transcriptionally and post-transcriptionally regulated by the HTLV-I protein p30

BMC Genomics

Volumn 10, Issue , 2009, Pages

  Taylor, John M ^a   Ghorbel, Sofiane ^a   Nicot, Christophe ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; CD53 ANTIGEN; COMPLEMENT FACTOR I; CONTACTIN; CONTACTIN 1; CYCLIN DEPENDENT KINASE 3; GLYCOGENIN; GLYCOGENIN 2; HEAT SHOCK TRANSCRIPTION FACTOR 1; HISTONE DEACETYLASE 3; HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEIN P30; LAMININ; LAMININ BETA 1; MESSENGER RNA; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE 1; PEROXIREDOXIN; PEROXIREDOXIN 3; PROTEIN P30; RIBOSOMAL PROTEIN L1; STEROID RECEPTOR COACTIVATOR 3; THYMOPOIETIN; UNCLASSIFIED DRUG; URIDINE KINASE; URIDINE KINASE 1; VIRUS PROTEIN; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 24; ZINC FINGER PROTEIN 31; ZINC FINGER PROTEIN 37A; CORE PROTEIN;

ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; REGULATORY MECHANISM; RNA PROCESSING; RNA TRANSCRIPTION; TRANSCRIPTION REGULATION; UPREGULATION; ACTIVE TRANSPORT; CELL LINE; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN T CELL LEUKEMIA VIRUS 1; METABOLISM; MONONUCLEAR CELL; T CELL LEUKEMIA;

HUMAN T-LYMPHOTROPIC VIRUS 1;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL LINE; DOWN-REGULATION; GENE EXPRESSION REGULATION; GENOME-WIDE ASSOCIATION STUDY; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; LEUKEMIA-LYMPHOMA, ADULT T-CELL; LEUKOCYTES, MONONUCLEAR; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; TRANSCRIPTION, GENETIC; UP-REGULATION; VIRAL CORE PROTEINS;

EID: 68649116289     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-10-311     Document Type: Article

References (57)

1. Poiesz BJ Ruscetti FW Reitz MS Kalyanaraman VS Gallo RC Isolation of a new type C retrovirus (HTLV) in primary uncultured cells of a patient with Sezary T-cell leukaemia Nature 1981, 294(5838):268-271 10.1038/ 294268a0 6272125
2. Miyoshi I Kubonishi I Yoshimoto S Akagi T Ohtsuki Y Shiraishi Y Nagata K Hinuma Y Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells Nature 1981, 294(5843):770-771 10.1038/294770a0 6275274
3. Yoshida M Seiki M Yamaguchi K Takatsuki K Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease Proc Natl Acad Sci USA 1984, 81(8):2534-2537 345097 6326131 10.1073/pnas.81.8.2534
4. Arisawa K Soda M Endo S Kurokawa K Katamine S Shimokawa I Koba T Takahashi T Saito H Doi H et al Evaluation of adult T-cell leukemia/ lymphoma incidence and its impact on non-Hodgkin lymphoma incidence in southwestern Japan Int J Cancer 2000, 85(3):319-324 10.1002/ (SICI)1097-0215(20000201)85:3<319::AID-IJC4>3.0.CO;2-B 10652420
5. Zhao LJ Giam CZ Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer Proc Natl Acad Sci USA 1991, 88(24):11445-11449 53152 1763059 10.1073/ pnas.88.24.11445
6. Zhao LJ Giam CZ Human T-cell lymphotropic virus type I(HTLV-I) transcriptional activator, Tax, enhances CREB binding toHTLV-I 21-base-pair repeats by protein-protein interaction Proc Natl Acad Sci USA 1992, 89(15):7070-7074 49647 1386673 10.1073/pnas.89.15.7070
7. Harrod R Kuo YL Tang Y Yao Y Vassilev A Nakatani Y Giam CZ p300 and p300/ cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complex J Biol Chem 2000, 275(16):11852-11857 10.1074/jbc.275.16.11852 10766811
8. Harrod R Tang Y Nicot C Lu HS Vassilev A Nakatani Y Giam CZ An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300 Mol Cell Biol 1998, 18(9):5052-5061 109090 9710589
9. Jiang H Lu H Schiltz RL Pise-Masison CA Ogryzko VV Nakatani Y Brady JN PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner Mol Cell Biol 1999, 19(12):8136-8145 84898 10567539
10. Lenzmeier BA Giebler HA Nyborg JK Human T-cell leukemia virus type 1 Tax requires direct access to DNA for recruitment of CREB binding protein to the viral promoter Mol Cell Biol 1998, 18(2):721-731 108783 9447968
11. Kwok RP Laurance ME Lundblad JR Goldman PS Shih H Connor LM Marriott SJ Goodman RH Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP Nature 1996, 380(6575):642-646 10.1038/380642a0 8602268
12. Seiki M Inoue J Hidaka M Yoshida M Two cis-acting elements responsible for posttranscriptional trans-regulation of gene expression of human T-cell leukemia virus type I Proc Natl Acad Sci USA 1988, 85(19):7124-7128 282136 3174625 10.1073/pnas.85.19.7124
13. Hakata Y Umemoto T Matsushita S Shida H Involvement of human CRM1 (exportin 1) in the export and multimerization of the Rex protein of human T-cell leukemia virus type 1 J Virol 1998, 72(8):6602-6607 109841 9658105
14. Hidaka M Inoue J Yoshida M Seiki M Post-transcriptional regulator (rex) of HTLV-1 initiates expression of viral structural proteins but suppresses expression of regulatory proteins Embo J 1988, 7(2):519-523 454349 2835230
15. Satou Y Yasunaga J Yoshida M Matsuoka M HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells Proc Natl Acad Sci USA 2006, 103(3):720-725 1334651 16407133 10.1073/ pnas.0507631103
16. Gaudray G Gachon F Basbous J Biard-Piechaczyk M Devaux C Mesnard JM The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription J Virol 2002, 76(24):12813-12822 136662 12438606 10.1128/ JVI.76.24.12813-12822.2002
17. Nicot C Dundr M Johnson JM Fullen JR Alonzo N Fukumoto R Princler GL Derse D Misteli T Franchini G HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication Nat Med 2004, 10(2):197-201 10.1038/nm984 14730358
18. Younis I Khair L Dundr M Lairmore MD Franchini G Green PL Repression of human T-cell leukemia virus type 1 and type 2 replication by a viral mRNA-encoded posttranscriptional regulator J Virol 2004, 78(20):11077-11083 521841 15452228 10.1128/JVI.78.20.11077-11083.2004
19. Ghorbel S Sinha-Datta U Dundr M Brown M Franchini G Nicot C Human T-cell leukemia virus type I p30 nuclear/nucleolar retention is mediated through interactions with RNA and a constituent of the 60 S ribosomal subunit J Biol Chem 2006, 281(48):37150-37158 10.1074/jbc.M603981200 17008317
20. Sinha-Datta U Datta A Ghorbel S Dodon MD Nicot C Human T-cell Lymphotrophic Virus Type I Rex and p30 Interactions Govern the Switch between Virus Latency and Replication J Biol Chem 2007, 282(19):14608-14615 10.1074/jbc.M611219200 17360706
21. Datta A Silverman L Phipps AJ Hiraragi H Ratner L Lairmore MD Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival Retrovirology 2007, 4:49 1937004 17634129 10.1186/1742-4690-4-49
22. Datta A Sinha-Datta U Dhillon NK Buch S Nicot C The HTLV-I p30 interferes with TLR4 signaling and modulates the release of pro- and anti-inflammatory cytokines from human macrophages J Biol Chem 2006, 281(33):23414-23424 10.1074/jbc.M600684200 16785240
23. Michael B Nair AM Hiraragi H Shen L Feuer G Boris-Lawrie K Lairmore MD Human T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes Retrovirology 2004, 1:39 538277 15560845 10.1186/1742-4690-1-39
24. Silverman LR Phipps AJ Montgomery A Ratner L Lairmore MD Human T-cell lymphotropic virus type 1 open reading frame II-encoded p30II is required for in vivo replication: Evidence of in vivo reversion J Virol 2004, 78(8):3837-3845 374265 15047799 10.1128/JVI.78.8.3837-3845.2004
25. Bartoe JT Albrecht B Collins ND Robek MD Ratner L Green PL Lairmore MD Functional role of pX open reading frame II of human T-lymphotropic virus type 1 in maintenance of viral loads in vivo J Virol 2000, 74(3):1094-1100 111443 10627519 10.1128/JVI.74.3.1094-1100.2000
26. Mori N Fujii M Cheng G Ikeda S Yamasaki Y Yamada Y Tomonaga M Yamamoto N Human T-cell leukemia virus type I tax protein induces the expression of anti-apoptotic gene Bcl-xL in human T-cells through nuclear factor-kappaB and c-AMP responsive element binding protein pathways Virus Genes 2001, 22(3):279-287 10.1023/A:1011158021749 11450946
27. Tsukahara T Kannagi M Ohashi T Kato H Arai M Nunez G Iwanaga Y Yamamoto N Ohtani K Nakamura M et al Induction of Bcl-x(L) expression by human T-cell leukemia virus type 1 Tax through NF-kappaB in apoptosis-resistant T-cell transfectants with Tax J Virol 1999, 73(10):7981-7987 112812 10482545
28. Taylor JM Nicot C HTLV-1 and apoptosis: Role in cellular transformation and recent advances in therapeutic approaches Apoptosis 2008, 13(6):733-747 2633601 18421579 10.1007/s10495-008-0208-7
29. Yang HS Jansen AP Nair R Shibahara K Verma AK Cmarik JL Colburn NH A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation Oncogene 2001, 20(6):669-676 10.1038/sj.onc.1204137 11314000
30. Chen Y Knosel T Kristiansen G Pietas A Garber ME Matsuhashi S Ozaki I Petersen I Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis J Pathol 2003, 200(5):640-646 10.1002/ path.1378 12898601
31. Gupta S Singh R Datta P Zhang Z Orr C Lu Z Dubois G Zervos AS Meisler MH Srinivasula SM et al The C-terminal tail of presenilin regulates Omi/ HtrA2 protease activity J Biol Chem 2004, 279(44):45844-45854 10.1074/ jbc.M404940200 15294909
32. Liu Y Wang Y Yamakuchi M Masuda S Tokioka T Yamaoka S Maruyama I Kitajima I Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax Oncogene 2001, 20(20):2514-2526 10.1038/sj.onc.1204364 11420661
33. Jeong SJ Pise-Masison CA Radonovich MF Park HU Brady JN Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells Oncogene 2005, 24(44):6719-6728 10.1038/ sj.onc.1208825 16007163
34. Tsukasaki K Tanosaki S DeVos S Hofmann WK Wachsman W Gombart AF Krebs J Jauch A Bartram CR Nagai K et al Identifying progression-associated genes in adult T-cell leukemia/lymphoma by using oligonucleotide microarrays Int J Cancer 2004, 109(6):875-881 10.1002/ijc.20028 15027121
35. Hayashi H Sano H Seo S Kume T The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression J Biol Chem 2008, 283(35):23791-23800 10.1074/jbc.M800190200 18579532
36. de La Fuente C Deng L Santiago F Arce L Wang L Kashanchi F Gene expression array of HTLV type 1-infected T cells: Up-regulation of transcription factors and cell cycle genes AIDS Res Hum Retroviruses 2000, 16(16):1695-1700 10.1089/08892220050193164 11080812
37. Ng PW Iha H Iwanaga Y Bittner M Chen Y Jiang Y Gooden G Trent JM Meltzer P Jeang KT Genome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-kappaB activation Oncogene 2001, 20(33):4484-4496 10.1038/ sj.onc.1204513 11494144
38. Pines J Hunter T Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport J Cell Biol 1991, 115(1):1-17 2289910 1717476 10.1083/jcb.115.1.1
39. Hsu YT Wolter KG Youle RJ Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis Proc Natl Acad Sci USA 1997, 94(8):3668-3672 20498 9108035 10.1073/pnas.94.8.3668
40. Migliorini D Lazzerini Denchi E Danovi D Jochemsen A Capillo M Gobbi A Helin K Pelicci PG Marine JC Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development Mol Cell Biol 2002, 22(15):5527-5538 133932 12101245 10.1128/ MCB.22.15.5527-5538.2002
41. Nomura J Matsumoto K Iguchi-Ariga SM Ariga H Mitochondria-independent induction of Fas-mediated apoptosis by MSSP Oncol Rep 2005, 14(5):1305-1309 16211301
42. Li J Wang J Nawaz Z Liu JM Qin J Wong J Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3 Embo J 2000, 19(16):4342-4350 302030 10944117 10.1093/emboj/19.16.4342
43. Guenther MG Lane WS Fischle W Verdin E Lazar MA Shiekhattar R A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness Genes Dev 2000, 14(9):1048-1057 316569 10809664
44. Chen L Fischle W Verdin E Greene WC Duration of nuclear NF-kappaB action regulated by reversible acetylation Science 2001, 293(5535):1653-1657 10.1126/science.1062374 11533489
45. Gregoire S Xiao L Nie J Zhang X Xu M Li J Wong J Seto E Yang XJ Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2 Mol Cell Biol 2007, 27(4):1280-1295 1800729 17158926 10.1128/MCB.00882-06
46. Chuang HC Chang CW Chang GD Yao TP Chen H Histone deacetylase 3 binds to and regulates the GCMa transcription factor Nucleic Acids Res 2006, 34(5):1459-1469 1401512 16528103 10.1093/nar/gkl048
47. Narita N Fujieda S Tokuriki M Takahashi N Tsuzuki H Ohtsubo T Matsumoto H Inhibition of histone deacetylase 3 stimulates apoptosis induced by heat shock under acidic conditions in human maxillary cancer Oncogene 2005, 24(49):7346-7354 10.1038/sj.onc.1208879 16044157
48. Doye V Wepf R Hurt EC A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution Embo J 1994, 13(24):6062-6075 395584 7813444
49. Cheng KW Lahad JP Gray JW Mills GB Emerging role of RAB GTPases in cancer and human disease Cancer Res 2005, 65(7):2516-2519 10.1158/ 0008-5472.CAN-05-0573 15805241
50. Kim JH Yang CK Heo K Roeder RG An W Stallcup MR CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes Mol Cell 2008, 31(4):510-519 2562329 18722177 10.1016/ j.molcel.2008.08.001
51. Zhang W Nisbet JW Albrecht B Ding W Kashanchi F Bartoe JT Lairmore MD Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300 J Virol 2001, 75(20):9885-9895 114560 11559821 10.1128/JVI.75.20.9885-9895.2001
52. Zhang W Nisbet JW Bartoe JT Ding W Lairmore MD Human T-lymphotropic virus type 1 p30(II) functions as a transcription factor and differentially modulates CREB-responsive promoters J Virol 2000, 74(23):11270-11277 113231 11070026 10.1128/JVI.74.23.11270-11277.2000
53. Itoh M Inoue J Toyoshima H Akizawa T Higashi M Yoshida M HTLV-1 rex and HIV-1 rev act through similar mechanisms to relieve suppression of unspliced RNA expression Oncogene 1989, 4(11):1275-1279 2682457
54. Hanly SM Rimsky LT Malim MH Kim JH Hauber J Duc Dodon M Le SY Maizel JV Cullen BR Greene WC Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements Genes Dev 1989, 3(10):1534-1544 10.1101/gad.3.10.1534 2482226
55. Naldini L Blomer U Gallay P Ory D Mulligan R Gage FH Verma IM Trono D In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector Science 1996, 272(5259):263-267 10.1126/ science.272.5259.263 8602510
56. Brazma A Hingamp P Quackenbush J Sherlock G Spellman P Stoeckert C Aach J Ansorge W Ball CA Causton HC et al Minimum information about a microarray experiment (MIAME)-toward standards for microarray data Nat Genet 2001, 29(4):365-371 10.1038/ng1201-365 11726920
57. Dennis G Jr Sherman BT Hosack DA Yang J Gao W Lane HC Lempicki RA DAVID: Database for Annotation, Visualization, and Integrated Discovery Genome Biol 2003, 4(5):P3 10.1186/gb-2003-4-5-p3 12734009